Hjem
Jian Wangs bilde

Jian Wang

Professor
  • E-postJian.Wang@uib.no
  • Telefon+47 55 58 63 46
  • Besøksadresse
    Jonas Lies vei 91
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Vis forfatter(e) 2021. miR-6858 plays a key role in the process of melatonin inhibition of the malignant biological behavior of glioma. Journal of clinical neuroscience. 137-146.
  • Vis forfatter(e) 2020. Ursodeoxycholic Acid Inhibits Glioblastoma Progression via Endoplasmic Reticulum Stress Related Apoptosis and Synergizes with the Proteasome Inhibitor Bortezomib. ACS Chemical Neuroscience. 1337-1346.
  • Vis forfatter(e) 2020. Trifluoperazine prolongs the survival of experimental brain metastases by STAT3-dependent lysosome membrane permeabilization. . American Journal of Cancer Research. 545-563.
  • Vis forfatter(e) 2020. TRIM22 activates NF-κB signaling in glioblastoma by accelerating the degradation of IκBα. . Cell Death and Differentiation. 367-381.
  • Vis forfatter(e) 2020. LncRNAs Predicted to Interfere With the Gene Regulation Activity of miR-637 and miR-196a-5p in GBM. Frontiers in Oncology. 1-10.
  • Vis forfatter(e) 2020. Identification of immune-related genes contributing to the development of glioblastoma using weighted gene co-expression network analysis. . Frontiers in Immunology.
  • Vis forfatter(e) 2020. Glioblastoma Therapy Using Codelivery of Cisplatin and Glutathione Peroxidase Targeting siRNA from Iron Oxide Nanoparticles. ACS Applied Materials & Interfaces.
  • Vis forfatter(e) 2020. Disulfiram, a ferroptosis inducer, triggers lysosomal membrane permeabilization by up-regulating ros in glioblastoma. OncoTargets and Therapy. 10631-10640.
  • Vis forfatter(e) 2019. Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma. EMBO Molecular Medicine.
  • Vis forfatter(e) 2019. The Natural Flavonoid Galangin Elicits Apoptosis, Pyroptosis, and Autophagy in Glioblastoma. Frontiers in Oncology.
  • Vis forfatter(e) 2019. Reduced expression of proteolipid protein 2 increases ER stress-induced apoptosis and autophagy in glioblastoma. Journal of Cellular and Molecular Medicine.
  • Vis forfatter(e) 2019. RNA splicing factor USP39 promotes glioma progression by inducing TAZ mRNA maturation. Oncogene.
  • Vis forfatter(e) 2019. PMEPA1 isoform a drives progression of glioblastoma by promoting protein degradation of the Hippo pathway kinase LATS1. Oncogene. 1-15.
  • Vis forfatter(e) 2019. Melatonin enhances proliferation and modulates differentiation of neural stem cells via autophagy in hyperglycemia. Stem Cells. 504-515.
  • Vis forfatter(e) 2019. Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-kappa B Signaling. Clinical Cancer Research. 6868-6881.
  • Vis forfatter(e) 2019. Interfering with long non-coding RNA MIR22HG processing inhibits glioblastoma progression through suppression of Wnt/β-catenin signalling. Brain. 512-530.
  • Vis forfatter(e) 2019. Immune checkpoint molecule herpes virus entry mediator is overexpressed and associated with poor prognosis in human glioblastoma. EBioMedicine. 159-170.
  • Vis forfatter(e) 2019. Hypoxic glioma-derived exosomes deliver microRNA-1246 to induce M2 macrophage polarization by targeting TERF2IP via the STAT3 and NF-κB pathways. Oncogene. 428-442.
  • Vis forfatter(e) 2018. YM155 decreases radiation-induced invasion and reverses epithelial–mesenchymal transition by targeting STAT3 in glioblastoma. Journal of Translational Medicine. 1-11.
  • Vis forfatter(e) 2018. Thioridazine inhibits autophagy and sensitizes glioblastoma cells to temozolomide. International Journal of Cancer. 1735-1745.
  • Vis forfatter(e) 2018. Six-Transmembrane Epithelial Antigen of Prostate 3 Predicts Poor Prognosis and Promotes Glioblastoma Growth and Invasion. Neoplasia. 543-554.
  • Vis forfatter(e) 2018. Matrine induces senescence of human glioblastoma cells through suppression of the IGF1/PI3K/AKT/p27 signaling pathway. Cancer Medicine. 4729-4748.
  • Vis forfatter(e) 2018. Inhibition of glioma growth by flavokawain B is mediated through endoplasmic reticulum stress induced autophagy. Autophagy. 2007-2022.
  • Vis forfatter(e) 2018. Glioma exosomes mediate the expansion and function of myeloid‐derived suppressor cells through microRNA‐29a/Hbp1 and microRNA‐92a/Prkar1a pathways. International Journal of Cancer. 3111-3126.
  • Vis forfatter(e) 2018. Actin like-6A promotes glioma progression through stabilization of transcriptional regulators YAP/TAZ article. Cell Death & Disease.
  • Vis forfatter(e) 2017. Tumour-associated glial host cells display a stem-like phenotype with a distinct gene expression profile and promote growth of GBM xenografts. BMC Cancer. 1-13.
  • Vis forfatter(e) 2017. Trifluoperazine, a novel autophagy inhibitor, increases radiosensitivity in glioblastoma by impairing homologous recombination. Journal of Experimental & Clinical Cancer Research. 1-13.
  • Vis forfatter(e) 2017. The combination of db-cAMP and ChABC with poly(propylene carbonate) microfibers promote axonal regenerative sprouting and functional recovery after spinal cord hemisection injury. Biomedicine and Pharmacotherapy. 354-362.
  • Vis forfatter(e) 2017. TGF-β2 initiates autophagy via Smad and non-Smad pathway to promote glioma cells' invasion. Journal of Experimental & Clinical Cancer Research.
  • Vis forfatter(e) 2017. TAGLN2 is a candidate prognostic biomarker promoting tumorigenesis in human gliomas. Journal of Experimental & Clinical Cancer Research.
  • Vis forfatter(e) 2017. Surgical debulking promotes recruitment of macrophages and triggers glioblastoma phagocytosis in combination with CD47 blocking immunotherapy. OncoTarget. 12145-12157.
  • Vis forfatter(e) 2017. Procollagen-lysine 2-oxoglutarate 5-dioxygenase 2 promotes hypoxia-induced glioma migration and invasion. OncoTarget. 23401-23413.
  • Vis forfatter(e) 2017. PDGFA/PDGFRα-regulated GOLM1 promotes human glioma progression through activation of AKT. Journal of Experimental & Clinical Cancer Research. 1-17.
  • Vis forfatter(e) 2017. Macrophage migration inhibitory factor promotes vasculogenic mimicry formation induced by hypoxia via CXCR4/AKT/EMT pathway in human glioblastoma cells. OncoTarget. 80358-80372.
  • Vis forfatter(e) 2017. Increased NG2 AND SOX2 expression is associated with high-grade choroid plexus tumors. Oncology Letters. 1802-1806.
  • Vis forfatter(e) 2017. Impact of VEGFA polymorphisms on glioma risk in Chinese. OncoTarget. 83712-83722.
  • Vis forfatter(e) 2017. High expression of RAB43 predicts poor prognosis and is associated with epithelial-mesenchymal transition in gliomas. Oncology Reports. 903-912.
  • Vis forfatter(e) 2017. Coiled-coil domain containing 109B is a HIF1?-regulated gene critical for progression of human gliomas. Journal of Translational Medicine.
  • Vis forfatter(e) 2017. Change in the relationship between the Australian summer monsoon circulation and boreal summer precipitation over Central China in the late 1990s. Meteorology and atmospheric physics (Print). 1-9.
  • Vis forfatter(e) 2017. Bufalin enhances radiosensitivity of glioblastoma by suppressing mitochondrial function and DNA damage repair. Biomedicine and Pharmacotherapy. 627-635.
  • Vis forfatter(e) 2016. Role of medical thoracoscopy in the treatment of tuberculous pleural effusion. Journal of Thoracic Disease. 52-60.
  • Vis forfatter(e) 2016. Oleuropein inhibits the proliferation and invasion of glioma cells via suppression of the AKT signaling pathway. Oncology Reports. 2009-2016.
  • Vis forfatter(e) 2016. Nitidine chloride inhibits the malignant behavior of human glioblastoma cells by targeting the PI3K/AKT/mTOR signaling pathway. Oncology Reports. 2160-2168.
  • Vis forfatter(e) 2016. Local in vitro delivery of rapamycin from electrospun PEO/PDLLA nanofibers for glioblastoma treatment. Biomedicine and Pharmacotherapy. 1345-1352.
  • Vis forfatter(e) 2016. Hypoxia promotes glioma-associated macrophage infiltration via periostin and subsequent M2 polarization by upregulating TGF-beta and M-CSFR. OncoTarget. 80521-80542.
  • Vis forfatter(e) 2016. Human astrocytes secrete IL-6 to promote glioma migration and invasion through upregulation of cytomembrane MMP14. OncoTarget. 62425-62438.
  • Vis forfatter(e) 2016. Galunisertib inhibits glioma vasculogenic mimicry formation induced by astrocytes. Scientific Reports.
  • Vis forfatter(e) 2016. CREBRF is a potent tumor suppressor of glioblastoma by blocking hypoxia-induced autophagy via the CREB3/ATG5 pathway. International Journal of Oncology. 519-528.
  • Vis forfatter(e) 2016. Berberine induces autophagy in glioblastoma by targeting the AMPK/mTOR/ULK1-pathway. OncoTarget. 66944-66958.
  • Vis forfatter(e) 2016. Association of HOTAIR polymorphisms rs4759314 and rs920778 with cancer susceptibility on the basis of ethnicity and cancer type. OncoTarget. 38775-38784.
  • Vis forfatter(e) 2015. Drug repurposing: Sulfasalazine sensitizes gliomas to gamma knife radiosurgery by blocking cystine uptake through system Xc<sup>-</sup>, leading to glutathione depletion. Oncogene. 5951-5959.
  • Vis forfatter(e) 2014. Rapid adherence to collagen IV enriches for tumour initiating cells in oral cancer. European Journal of Cancer. 3262-3270.
  • Vis forfatter(e) 2014. Interrogation of gossypol therapy in glioblastoma implementing cell line and patient-derived tumour models. British Journal of Cancer. 2275-2286.
  • Vis forfatter(e) 2014. Dynamic contrast enhanced MRI detects early response to adoptive NK cellular immunotherapy targeting the NG2 proteoglycan in a rat model of glioblastoma. PLOS ONE.
  • Vis forfatter(e) 2014. Dynamic Contrast Enhanced MRI Detects Early Response to Adoptive NK Cellular Immunotherapy Targeting the NG2 Proteoglycan in a Rat Model of Glioblastoma. PLOS ONE. 12 sider.
  • Vis forfatter(e) 2014. A novel GFP nude rat model to investigate tumor-stroma interactions. Cancer Cell International.
  • Vis forfatter(e) 2014. A co-culture model with brain tumor-specific bioluminescence demonstrates astrocytes-induced drug resistance in glioblastoma. Journal of Translational Medicine.
  • Vis forfatter(e) 2013. Targeting glioblastoma with NK cells and mAb against NG2/CSPG4 prolongs animal survival. OncoTarget. 1527-1546.
  • Vis forfatter(e) 2013. Gamma knife surgery as monotherapy with clinically relevant doses prolongs survival in a Human GBM Xenograft Model. Biomedical Research. 9 sider.
  • Vis forfatter(e) 2013. Establishment of a novel dsRed NOD/Scid mouse strain to investigate the host and tumor cell compartments. Cancer Investigation. 221-230.
  • Vis forfatter(e) 2013. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. Acta Neuropathologica. 683-698.
  • Vis forfatter(e) 2013. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. PLOS ONE. e59773.
  • Vis forfatter(e) 2012. The CD47-signal regulatory protein alpha (SIRPa) interaction is a therapeutic target for human solid tumors. Proceedings of the National Academy of Sciences of the United States of America. 6662-6667.
  • Vis forfatter(e) 2012. Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 10 sider.
  • Vis forfatter(e) 2012. Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multimodal small-animal PET and MRI. Journal of Nuclear Medicine. 1135-1145.
  • Vis forfatter(e) 2011. Targeting the NG2/CSPG4 Proteoglycan Retards Tumour Growth and Angiogenesis in Preclinical Models of GBM and Melanoma. PLOS ONE. 14 sider.
  • Vis forfatter(e) 2011. Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. BMC Cancer.
  • Vis forfatter(e) 2011. Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 3749-3754.
  • Vis forfatter(e) 2011. A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. Neuropathology and Applied Neurobiology. 189-205.
  • Vis forfatter(e) 2010. alpha B-Crystallin Is Elevated in Highly Infiltrative Apoptosis-Resistant Glioblastoma Cells. American Journal of Pathology. 1618-1628.
  • Vis forfatter(e) 2010. Glioma cell populations grouped by different cell type markers drive brain tumor growth. Cancer Research. 4274-4279.
  • Vis forfatter(e) 2010. Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment. Gene Therapy. 202-216.
  • Vis forfatter(e) 2009. iTRAQ-based proteomics profiling reveals increased metabolic activity and cellular cross-talk in angiogenic compared with invasive glioblastoma phenotype. Molecular & Cellular Proteomics. 2595-2612.
  • Vis forfatter(e) 2009. Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. Neuropathology and Applied Neurobiology. 380-393.
  • Vis forfatter(e) 2009. Activated Platelets Provide a Functional Microenvironment for the Antiangiogenic Fragment of Histidine-Rich Glycoprotein. Molecular Cancer Research. 1792-1802.
  • Vis forfatter(e) 2009. A reproducible brain tumour model established from human glioblastoma biopsies. BMC Cancer.
  • Vis forfatter(e) 2008. Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. NMR in Biomedicine. 830-838.
  • Vis forfatter(e) 2008. The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene. 5182-5194.
  • Vis forfatter(e) 2008. Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma. Clinical Cancer Research. 1571-1580.
  • Vis forfatter(e) 2008. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. International Journal of Cancer. 761-768.
  • Vis forfatter(e) 2007. Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. Journal of Neuro-Oncology. 1-10.
  • Vis forfatter(e) 2006. Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Research. 9895-9902.
  • Vis forfatter(e) 2006. Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. Neuropathology and Applied Neurobiology. 419-427.
  • Vis forfatter(e) 2006. Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. Neuro-Oncology. 96-108.
  • Vis forfatter(e) 2006. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proceedings of the National Academy of Sciences of the United States of America. 16466-16471.
Mastergradsoppgave
  • Vis forfatter(e) 2021. Development of 3D in vitro Interaction Models for the Evaluation and Treatment of Brain Metastases.
Doktorgradsavhandling
  • Vis forfatter(e) 2016. Experimental modeling and therapeutic strategies in glioblastoma.
  • Vis forfatter(e) 2008. Xenografted brain tumors for modelling glioma biology – a study of brain tumor initiating cells and phenotypic modulation in gliomas.
Sammendrag/abstract
  • Vis forfatter(e) 2013. EGFR wild-type amplification and activation promote invasion and development of glioblastoma independent of angiogenesis. Neuro-Oncology. 6-6.
  • Vis forfatter(e) 2012. Early MRI findings of targeting the NG2 proteoglycan in GBM. The FASEB Journal. 1 sider.
  • Vis forfatter(e) 2011. Separate analysis of the cancer and stroma cell populations from orthotopically implanted tumor biopsies in eGFP scid mice. Clinical and Experimental Metastasis. 203-203.
  • Vis forfatter(e) 2010. THERAPEUTIC TARGETING OF THE NG2 PROTEOGLYCAN WITH MAB 9.2.27 AND ADOPTIVELY TRANSFERRED NK CELLS LYSES HUMAN GLIOBLASTOMA MULTIFORME IN VIVO. Neuro-Oncology. 9-9.
  • Vis forfatter(e) 2010. SULFASALAZINE SENSITIZES GLIOBLASTOMA CELLS TO RADIATION TREATMENT. Neuro-Oncology. 109-109.
  • Vis forfatter(e) 2010. Rapid adherence to collagen IV enriches for tumour initiating cells. European Journal of Cancer. 124-124.
  • Vis forfatter(e) 2010. ANTI-ANGIOGENIC TREATMENT IN A CLINICALLY RELEVANT GLIOBLASTOMA MODEL REDUCES BLOOD FLOW AND INCREASES TUMOR CELL INVASION. Neuro-Oncology. 20-20.
  • Vis forfatter(e) 2009. Targeting the tumor stroma: a novel therapeutic strategy based on separate analysis of the malignant and stromal cell compartments in brain tumors. Neuro-Oncology. 221-222.
  • Vis forfatter(e) 2009. TARGETING THE TUMOR STROMA: A NOVEL THERAPEUTIC STRATEGY BASED ON SEPARATE ANALYSIS OF THE MALIGNANT AND STROMAL CELL COMPARTMENTS IN BRAIN TUMORS. Neuro-Oncology. 965-965.
  • Vis forfatter(e) 2009. PHENOTYPIC MODULATION OF EXPERIMENTAL GLIOMAS: PROGRESSION FROM GLIOMATOSIS CEREBRI-LIKE LESIONS TO GLIOBLASTOMA. Neuro-Oncology. 897-897.
  • Vis forfatter(e) 2009. PHENOTYPIC AND PHYSIOLOGIC EFFECTS OF BEVACIZUMAB IN A HIGHLY INFILTRATIVE AND ANGIOGENIC HUMAN GLIOBLASTOMA MODEL. Neuro-Oncology. 906-906.
  • Vis forfatter(e) 2009. MOLECULAR VARIATIONS IN TUMOR-HOST INTERACTIONS BETWEEN INVASIVE AND ANGIOGENIC PHENOTYPE IN HIGH-GRADE GLIOMAS. Neuro-Oncology. 961-961.
  • Vis forfatter(e) 2009. CD133-NEGATIVE GLIOMA SUBPOPULATIONS GROUPED BY DIFFERENT CELL TYPE MARKERS DISPLAY TUMORIGENICITY IN VIVO. Neuro-Oncology. 917-917.
  • Vis forfatter(e) 2008. Human glioblastoma tissue engraftment in immunocompetent rodent hosts. Neuro-Oncology. 815-815.
  • Vis forfatter(e) 2008. DEVELOPMENT OF A NEW BRAIN METASTASES MODEL IN IMMUNODEFICIENT ANIMALS. Neuro-Oncology. 854-854.
  • Vis forfatter(e) 2008. CD133-NEGATIVE GLIOMA SUBPOPULATIONS GROUPED BY DIFFERENT CELL TYPE MARKERS DISPLAY TUMORGENICITY IN VIVO. Neuro-Oncology. 778-778.
  • Vis forfatter(e) 2005. Bacitracin inhibits glioma cell migration and invasion in vitro. Neuro-Oncology. 357-357.
  • Vis forfatter(e) 2004. Forced differentiation suppresses the proliferative rate of cancer cells in brain tumours. Neuro-Oncology.
  • Vis forfatter(e) 2004. Angiogenesis-independent growth by brain tumor cells exhibiting cancer stem cell properties. Neuro-Oncology. 309-309.
Poster
  • Vis forfatter(e) 2009. Highly infiltrative brain tumors show reduced chemosensitivity associated with a stem cell-like phenotype.
Vitenskapelig oversiktsartikkel/review
  • Vis forfatter(e) 2018. Lysosomes contribute to radioresistance in cancer. Cancer Letters. 39-46.
  • Vis forfatter(e) 2018. Chemoresistance caused by the microenvironment of glioblastoma and the corresponding solutions. Biomedicine and Pharmacotherapy. 39-46.

Se fullstendig oversikt over publikasjoner i CRIStin.

1.         Poli A, Wang J, Domingues O, Yan T, Thuen M, Thorsen F, Rygh CB, McCormack E, Fischer W, Planaguma J, Hentges F, Pedersen PH, Zimmer J, Enger PØ, and Chekenya M. Targeting NG2 with mAb9.2.27 activated NK-cells promotes microglial cytotoxicity against GBM, prolonging survival in rats (Co-first author, Oncotarget. 2013 Sep;4(9):1527-46)

2.         Skeie BS, Wang J, Dodoo E, Heggdal JI, Grønli J, Sleire L, Bragstad S, Chekenya M, Mørk S, Pedersen PH, Enger PØ, and Ganz JC. Gamma Knife Surgery as monotherapy with clinically relevant doses Prolongs Survival in a Human GBM Xenograft Model. (Biomed Res Int. 2013;2013:139674. doi: 10.1155/2013/139674. Epub 2013 Nov 10).

3.         Talasila KM, Soentgerath A, Euskirchen P, Rosland GV, Wang J, Huszthy PC, Prestegarden L, Skaftnesmo KO, Brekka N, Nigro J, Lund-Johansen M, Mørk S, Enger PØ, Bjerkvig R and MiletiC H. EGFR activation promotes invasion and tumor development independent of angiogenesis. (Acta Neuropathologica, Epub 2013 Feb 22)

4.         Klink B, Miletic H, Stieber D, Huszthy P, Valenzuela JAC, Balss J, Wang J, Schubert M, Sakariassen PØ, Sundstrøm T, Torsvik A, Aarhus M, Mahesparan R, Deimling AV, Kaderali L, Niclou S, Schröck E, Bjerkvig R, Nigro J. A novel, diffusely infiltrative xenograft model of human anaplastic oligodendroglioma with mutations in FUBP1, CIC, and IDH1. (Plos one, Epub 2013 Mar 19)

5.         Jacobsen HK, Sleire L, Wang J, Netland IA, Mutlu E, Førde H, Pedersen PH, Gullberg Dand Enger PØ. Establishment of a novel dsRed NOD/Scid mouse strain to investigate the host and tumor cell compartments. (Cancer investigation, 2013 May;31(4):221-30)

6.         Kim DK, Wang J, Willingham SB, Martin R, Wernig G, and Weissman IL. Anti-CD47 antibodies promote phagocytosis and inhibit the growth of human myeloma cells. Leukemia. 2012 May 30. doi: 10.1038/leu.2012.140. [Epub ahead of print]

7.         Viel T, Talasila T, Talasila KM, Monfared P, Wang J, Jikeli JfF, Waerzeggers Y, Neumaier B, Backes H, Brekka N, Thorsen F, Stieber D, Niclou SP, Winkeler A, Tavitian B, Hoehn M, Bjerkvig R, Miletic H, and Jacobs A. Analysis of the growth dynamics of angiogenesis-dependent and -independent experimental glioblastomas by multi-modal µPET and µMRI. J Nucl Med. 2012 Jul;53(7):1135-45. Epub 2012 Jun 11.

8.         Willingham SB, Volkmer JP, Gentles AJ, Sahoo D, Dalerba P, Mitra SS, Wang J, Contreras-Trujillo H, Martin R, Cohen JD, Lovelace P, Scheeren FA, Chao MP, Weiskopf K, Tang C, Volkmer AK, Naik TJ, Storm TA, Mosley AR, Edris B, Schmid SM, Sun CK, Chua MS, Murillo O, Rajendran P, Cha AC, Chin RK, Kim D, Adorno M, Raveh T, Tseng D, Jaiswal S, Enger PO, Steinberg GK, Li G, So SK, Majeti R, Harsh GR, van de Rijn M, Teng NN, Sunwoo JB, Alizadeh AA, Clarke MF, Weissman IL. CD47 Is A Therapeutic Target On Human Solid Tumor Cells. Proc Natl Acad Sci U S A. 2012 Apr 24;109(17):6662-7. Epub 2012 Mar 26.

9.         Moen I, Jevne C, Wang J, Kalland KH, Chekenya M, Akslen LA, Sleire L, Enger PØ, Reed RK, Øyan AM and Stuhr L. Tumor-stroma interactions in red 4T1 mammary tumors in green mice with and without enhanced oxygenation. BMC Cancer. 2012 Jan 17;12:21.

10.       Yan T, Skaftnesmo KO, Leiss L, Sleire L, Wang J, Li XG, Enger PO. Neuronal markers are expressed in human gliomas and NSE knockdown sensitizes glioblastoma cells to radiotherapy and temozolomide. BMC Cancer. 2011 Dec 20;11:524.

11.       Wang J, Svendsen A, Kmiecik J, Miletic H, Immervoll H, Planaguma J, Bjerkvig R, Enger PØ, Rygh CB,  Chekenya M. Targeting the NG2 proteoglycan retards tumour growth and angiogenesis in preclinical models of GBM and melanoma. (PLoS One. 2011;6(7):e23062. Epub 2011 Jul 29).

12.       Keunen O, Johansson M, Oudin A, Sanzey M, Rahim SAA, Fack F, Thorsen F, Taxt T, Bartos M, Jirik R, Miletic H, Wang J, Stuhr L, Moen I, Brekke C, Bjerkvig B and Niclou1 SP. Bevacizumab reduces blood flow and increases tumor cell invasion in glioblastomas. Proc Natl Acad Sci U S A. 2011 Mar 1;108(9):3749-54.

13.       Wang J, Daphu I, Pedersen PH, Miletic H, Hovland R, Mørk S, Bjerkvig R, Tiron C, McCormack E, Micklem D, Lorens JB, Immervoll H, Thorsen F. A novel brain metastases model developed in immunodeficient rats closely mimics the growth of metastatic brain tumours in patients. Neuropathol Appl Neurobiol. 2011 Feb;37(2):189-205.

14.       Goplen D, Bougnaud S, Rajcevic U, Bøe SO, Skaftnesmo KO, Voges J, Enger PO, Wang J, Tysnes BB, Laerum OD, Niclou S, Bjerkvig R. {alpha}B-Crystallin is elevated in highly infiltrative apoptosis-resistant glioblastoma cells. Am J Pathol. 2010 Oct;177(4):1618-28. Epub 2010 Sep 2.

15.       Prestegarden L, Svendsen A, Wang J, Sleire L, Skaftnesmo KO, Bjerkvig R, Yan T, Askland L, Persson A, Sakariassen PØ, Enger PØ. Glioma cell populations grouped by different cell type markers drive brain tumor growth. Cancer Res. 2010 Jun 1; 70(11): 4274-9.

16.       Huszthy PC, Immervoll H, Wang J, Goplen D, Miletic H, Eide GE, Bjerkvig R. Cellular effects of oncolytic viral therapy on the glioblastoma microenvironment. Gene Ther. 2010 Feb; 17(2): 202-16.

17.       Wang J, Miletic H, Per Ø Sakariassen, Peter C Huszthy, Hege Jacobsen, Narve Brekka, Xingang Li, Peng Zhao, Sverre Mørk, Martha Chekenya, Rolf Bjerkvig and Per Ø Enger. A standardised brain tumor model established from the human glioblastoma multiforme biopsies. BMC Cancer. 2009 Dec 29; 9:465.

18.       Thulin Å, Ringvall M, Dimberg A, Kårehed K, Väisänen T, Väisänen MR, Hamad O, Wang J, Bjerkvig R, Nilsson B, Pihlajaniemi T, Åkerud H, Pietras K, Jahnen-Dechent W, Siegbahn A, Olsson AK. Activated platelets provide a functional microenvironment for the anti-angiogenic fragment of histidine-rich glycoprotein. Mol Cancer Res. 2009 Nov; 7(11): 1792-802. Epub 2009 Nov 10.

19.       Rajcevic U, Petersen K, Knol JC, Loos M, Bougnaud S, Klychnikov O, Li KW, Pham TV, Wang J, Miletic H, Peng Z, Bjerkvig R, Jimenez CR, Niclou SP. iTRAQ based proteomic profiling reveals increased metabolic activity and cellular crosstalk in angiogenic compared to invasive Glioblastoma phenotype. Mol Cell Proteomics. 2009 Nov;8(11): 2595-612. Epub 2009 Aug 12.

20.      Johannessen TC, Wang J, Skaftnesmo KO, Sakariassen PØ, Enger PØ, Petersen K, Øyan AM, Kalland KH, Bjerkvig R, Tysnes BB. Highly infiltrative brain tumours show reduced chemosensitivity associated with a stem cell-like phenotype. Neuropathol Appl Neurobiol. 2009 Aug; 35(4): 380-93.

21.       Thorsen F, Jirak D, Wang J, Sykova E, Bjerkvig R, Enger PØ, van der Kogel A, Hajek M. Two distinct tumor phenotypes isolated from glioblastomas show different MRS characteristics. NMR Biomed. 2008 Oct; 21(8): 830-8.

22.       Chekenya M, Krakstad C, Svendsen A, Netland IA, Staalesen V, Tysnes BB, Selheim F, Wang J, Sakariassen PØ, Sandal T, Lønning PE, Flatmark T, Enger PØ, Bjerkvig R, Sioud M, Stallcup WB. The progenitor cell marker NG2/MPG promotes chemoresistance by activation of integrin-dependent PI3K/Akt signaling. Oncogene. 2008 Sep 4; 27(39): 5182-94. Epub 2008 May 12.

23.       Huszthy PC, Goplen D, Thorsen F, Immervoll H, Wang J, Gutermann A, Miletic H, Bjerkvig R. Oncolytic herpes simplex virus type-1 therapy in a highly infiltrative animal model of human glioblastoma. Clin Cancer Res. 2008 Mar 1; 14 (5): 1571-80.

24.       Wang J, Sakariassen PØ, Tsinkalovsky O, Immervoll H, Bøe SO, Svendsen A, Prestegarden L, Røsland G, Thorsen F, Stuhr L, Molven A, Bjerkvig R, Enger PØ. CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. Int J Cancer. 2008 Feb 15; 122 (4):761-8.

25.       Sakariassen PØ, Prestegarden L, Wang J, Skaftnesmo KO, Mahesparan R, Molthoff C, Sminia P, Sundlisaeter E, Misra A, Tysnes BB, Chekenya M, Peters H, Lende G, Kalland KH, Øyan AM, Petersen K, Jonassen I, van der Kogel A, Feuerstein BG, Terzis AJ, Bjerkvig R, Enger PØ. Angiogenesis-independent tumor growth mediated by stem-like cancer cells. Proc Natl Acad Sci U S A. 2006 Oct 31;103 (44):16466-71. Epub 2006 Oct 20.

26.       Goplen D, Wang J, Enger PØ, Tysnes BB, Terzis AJ, Laerum OD, Bjerkvig R. Protein disulfide isomerase expression is related to the invasive properties of malignant glioma. Cancer Res. 2006 Oct 15; 66 (20): 9895-902.

27.       Thorsen F, Enger PØ, Wang J, Bjerkvig R, Pedersen PH. Human glioblastoma biopsy spheroids xenografted into the nude rat brain show growth inhibition after stereotactic radiosurgery. J Neurooncol. 2007 Mar; 82 (1): 1-10. Epub 2006 Sep 6.

28.       Sundlisaeter E, Wang J, Sakariassen PØ, Marie M, Mathisen JR, Karlsen BO, Prestegarden L, Skaftnesmo KO, Bjerkvig R, Enger PØ. Primary glioma spheroids maintain tumourogenicity and essential phenotypic traits after cryopreservation. Neuropathol Appl Neurobiol. 2006 Aug; 32 (4): 419-27.

29.       Piepoli T, Jakupoglu C, Gu W, Lualdi E, Suarez-Merino B, Poliani PL, Cattaneo MG, Ortino B, Goplen D, Wang J, Mola R, Inverardi F, Frassoni C, Bjerkvig R, Steinlein O, Vicentini LM, Brüstle O, Finocchiaro G. Expression studies in gliomas and glial cells do not support a tumor suppressor role for LGI1. Neuro Oncol. 2006 Apr; 8(2): 96-108. Epub 2006 Mar 2.

Book chapter: Wang, J. Terzis. A.J.A, Aboody, K. Enger, PO and Bjerkvig, R. Transplants for Glioblastoma In Cell Transplantation from Laboratory to Clinic, Elsevier Publishers, C. Halberstadt and D. Emerich eds. (2007)