Hjem
Lars A. Akslens bilde

Lars A. Akslen

Professor, Leder for CCBIO
  • E-postLars.Akslen@uib.no
  • Telefon+47 55 97 31 82
  • Besøksadresse
    Patologisk avdeling, Sentralblokka 2 etg., Haukeland Universitetssjukehus (HUS)
    evt. CCBIO, Sentralblokka 2 etg., HUS
  • Postadresse
    Postboks 7804
    5020 Bergen

Akslen er en sertifisert spesialist i kirurgisk patologi og leder forskningsgruppen Tumor Biology Research Group (etablert i 1995) ved Klinisk Institutt 1, Universitetet i Bergen. Siden 2013 har Akslen vært senterleder for Centre for Cancer Biomarkers CCBIO. Akslens gruppe og CCBIO arbeider med translasjonell kreftforskning med fokus på nye kreftmarkører og målrettet behandling og særlig mekanismer knyttet til hvordan kreftceller påvirkes av mikromiljøet i svulstene, og den betydning dette har for kreftspredning og dårlig prognose. Gruppen har prosjekter på ulike kreftformer, som brystkreft, ondartet melanom, prostatakreft og gynekologisk kreft. Gruppen kombinerer studier av humane tumorprøver med eksperimentelle celle- og dyremodeller. Det overordnede målet er å finne nye biomarkører som kan hjelpe oss til å forutse hvordan aggressive svulster vil utvikle seg og dermed bedre kunne skreddersy behandling.

Vitenskapelig artikkel
  • Ramnefjell, Maria; Aamelfot, Christina; Helgeland, Lars; Akslen, Lars A. 2017. Vascular invasion is an adverse prognostic factor in resected non?small-cell lung cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 197-206.
  • Klingen, Tor Audun; Chen, Ying; Aas, Hans; Wik, Elisabeth; Akslen, Lars A. 2017. Tumor-associated macrophages are strongly related to vascular invasion, non-luminal subtypes, and interval breast cancer. Human Pathology. 72-80.
  • Kraby, Maria Ryssdal; Opdahl, Signe; Akslen, Lars A.; Bofin, Anna M. 2017. Quantifying tumour vascularity in non-luminal breast cancers. Journal of Clinical Pathology. 766-774.
  • Berg, Anna; Gulati, Ankush; Ytre-Hauge, Sigmund; Fasmer, Kristine Eldevik; Mauland, Karen Klepsland; Høivik, Erling Andre; Husby, Jenny Hild Aase; Tangen, Ingvild Løberg; Trovik, Jone; Halle, Mari Kyllesø; Stefansson, Ingunn; Akslen, Lars A.; Woie, Kathrine; Bjørge, Line; Salvesen, Helga; Salvesen, Øyvind; Werner, Henrica Maria Johanna; Haldorsen, Ingfrid S.; Krakstad, Camilla. 2017. Preoperative imaging markers and PDZ-binding kinase tissue expression predict low-risk disease in endometrial hyperplasias and low grade cancers. OncoTarget. 68530-68541.
  • Pilskog, Martin; Beisland, Christian; Akslen, Lars A.; Bostad, Leif; Haug, Åse; Heinrich, Daniel; Hjelle, Karin Margrethe; Straume, Oddbjørn. 2017. Predictive value of C-reactive protein in patients treated with sunitinib for metastatic clear cell renal cell carcinoma. BMC Urology. 1-11.
  • Reisæter, Lars Anders Rokne; Futterer, Jürgen J.; Losnegård, Are; Nygård, Yngve; Monssen, Jan Anker; Gravdal, Karsten; Halvorsen, Ole Johan; Akslen, Lars A.; Biermann, Martin; Haukaas, Svein Andreas; Rørvik, Jarle; Beisland, Christian. 2017. Optimising preoperative risk stratification tools for prostate cancer using mpMRI. European Radiology. 1016-1026.
  • Ramnefjell, Maria; Aamelfot, Christina; Helgeland, Lars; Akslen, Lars A. 2017. Low expression of SerpinB2 is associated with reduced survival in lung adenocarcinomas. OncoTarget. 90706-90718.
  • Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. 2017. FGD5 amplification in breast cancer patients is associated with tumor proliferation and a poorer prognosis. Breast Cancer Research and Treatment. 243-253.
  • Aziz, Sura Mohammed; Wik, Elisabeth; Knutsvik, Gøril; Klingen, Tor Audun; Chen, Ying; Davidsen, Benedicte; Aas, Hans; Aas, Turid; Akslen, Lars A. 2017. Extra-nodal extension is a significant prognostic factor in lymph node positive breast cancer. PLOS ONE. 1-15.
  • Tangen, Ingvild Løberg; Venereis, Jennifer Taylor; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Trovik, Jone; Akslen, Lars A.; Salvesen, Helga; Conzen, Suzanne D.; Fleming, Gini F.; Krakstad, Camilla. 2017. Expression of glucocorticoid receptor is associated with aggressive primary endometrial cancer and increases from primary to metastatic lesions. Gynecologic Oncology. 672-677.
  • Krüger, Kristi; Wik, Elisabeth; Knutsvik, Gøril; Nalwoga, Hawa; Klingen, Tor Audun; Arnes, Jarle; Chen, Ying; Mannelqvist, Monica; Dimitrakopoulou, Konstantina; Stefansson, Ingunn; Birkeland, Even; Aas, Turid; Tobin, Nicholas P.; Jonassen, Inge; Bergh, Jonas; Foulkes, William D; Akslen, Lars A. 2017. Expression of Nestin associates with BRCA1 mutations, a basal-like phenotype and aggressive breast cancer. Scientific Reports. 1-12.
  • Fonnes, Tina; Berg, Hege Fredriksen; Onyango, Therese Bredholt; Edquist, Per-Henrik D.; Sortland, Kristina; Berg, Anna; Salvesen, Helga; Akslen, Lars A.; Werner, Henrica Maria Johanna; Trovik, Jone; Tangen, Ingvild Løberg; Krakstad, Camilla. 2017. Asparaginase-like protein 1 is an independent prognostic marker in primary endometrial cancer, and is frequently lost in metastatic lesions. Gynecologic Oncology. 197-203.
  • Knutsvik, Gøril; Collett, Karin; Arnes, Jarle; Akslen, Lars A.; Stefansson, Ingunn. 2016. QSOX1 expression is associated with aggressive tumor features and reduced survival in breast carcinomas. Modern Pathology. 1485-1491.
  • Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe. 2016. Molecular subtypes of breast cancer: Long-term incidence trends and prognostic differences. Cancer Epidemiology, Biomarkers and Prevention. 1625-1634.
  • Helsing, Per; Robsahm, Trude Eid; Vos, Linda; Rizvi, Syed Mohammad H.; Akslen, Lars A.; Veierød, Marit Bragelien. 2016. Cutaneous head and neck melanoma (CHNM): A population-based study of the prognostic impact of tumor location. Journal of American Academy of Dermatology. 975-982.
  • Mauland, Karen Klepsland; Wik, Elisabeth; Høivik, Erling Andre; Kusonmano, Kanthida; Halle, Mari Kyllesø; Berg, Anna; Haugland, Hans Kristian; Øyan, Anne Margrete; Kalland, Karl-Henning; Stefansson, Ingunn; Akslen, Lars A.; Krakstad, Camilla; Trovik, Jone; Werner, Henrica Maria Johanna; Salvesen, Helga. 2016. Aneuploidy related transcriptional changes in endometrial cancer link low expression of chromosome 15q genes to poor survival. OncoTarget. 9696-9707.
  • Moshina, Nataliia; Ursin, Giske; Hoff, Solveig Roth; Akslen, Lars A.; Roman, Martha; Sebuødegård, Sofie; Hofvind, Solveig. 2015. Mammographic density and histopathologic characteristics of screen-detected tumors in the Norwegian Breast Cancer Screening Program. Acta radiologica open.
  • Knappskog, Stian; Berge, Elisabet Ognedal; Chrisanthar, Ranjan; Geisler, Stephanie; Staalesen, Vidar; Leirvaag, Beryl; Yndestad, Synnøve; de Faveri, Elise Norheim; Karlsen, Bård Ove; Wedge, David C.; Akslen, Lars A.; Lilleng, Peer Kåre; Løkkevik, Erik; Lundgren, Steinar; Østenstad, Bjørn; Risberg, Terje; Mjaaland, Ingvil; Aas, Turid; Lønning, Per Eystein. 2015. Concomitant inactivation of the p53- and pRB- functional pathways predicts resistance to DNA damaging drugs in breast cancer in vivo. Molecular Oncology. 1553-1564.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2014. Nestin expression is associated with aggressive cutaneous melanoma of the nodular type. Modern Pathology. 396-401.
  • Mackay, Helen; Eisenhauer, Elizabeth A.; Kamel-Reid, Suzanne; Tsao, Ming-Sound; Clarke, Blaise; Karakasis, Katherine; Werner, Henrica Maria Johanna; Trovik, Jone; Akslen, Lars A.; Salvesen, Helga Birgitte; Dongsheng, Tu; Oza, Amit M. 2014. Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer. Cancer. 603-610.
  • Ojesina, Akinyemi; Lichtenstein, Lee; Freeman, Samuel S.; Pedamallu, Chandra Sekhar ; Imaz-Rosshandler, I; Pugh, Trevor J.; Cherniack, Andrew D.; Ambrogio, Lauren; Cibulskis, Kristian; Bertelsen, Bjørn; Romero-Cordoba, S; Treviño, Victor; Vazquez-Santillan, K; Guadarrama, Alberto Salido; Wright, Alexi A.; Rosenberg, Mara W.; Duke, Fujiko; Kaplan, Bethany; Wang, Rui; Nickerson, Elizabeth; Walline, Heather M; Lawrence, Michael S.; Stewart, Chip; Carter, Scott L.; McKenna, Aaron; Rodriguez-Sanchez, Iram P.; Espinosa-Castilla, Magali; Woie, Kathrine; Bjørge, Line; Wik, Elisabeth; Halle, Mari Kyllesø; Høivik, Erling Andre; Krakstad, Camilla; Gabiño, Nayeli Belem; Gómez-Macías, Gabriela; Valdez-Chapa, Lezmes D.; Garza-Rodríguez, Maria Lourdes; Maytorena, German; Vazquez, Jorge; Rodea, Carlos; Cravioto, Adrian; Cortes, Maria L.; Greulich, Heidi; Crum, Christopher P.; Neuberg, Donna S.; Hidalgo-Miranda, Alfredo; Escareno, Claudia Rangel; Akslen, Lars A.; Carey, Thomas E.; Vintermyr, Olav Karsten; Gabriel, Stacey B.; Barrera-Saldana, Hugo A.; Melendez-Zajgla, Jorge; Getz, Gad; Salvesen, Helga Birgitte; Meyerson, Matthew. 2014. Landscape of genomic alterations in cervical carcinomas. Nature. 371-375.
  • Haldorsen, Ingfrid S.; Stefansson, Ingunn; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Taxt, Torfinn; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas. British Journal of Cancer. 107-114.
  • Lia, Wenliang; Ai, Nanping; Wang, Suming; Bhattacharya, Nandita; Vrbanac, Vladimir; Collins, Michael; Signoretti, Sabina; Hu, Yanhui; Boyce, Frederick M.; Gravdal, Karsten; Halvorsen, Ole Johan; Nalwoga, Hawa; Akslen, Lars A.; Harlow, Ed; Watnick, Randolph S. 2014. GRK3 is essential for metastatic cells and promotes prostate tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 1521-1526.
  • Nygård, Yngve; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2014. A positive real-time elastography is an independent marker for detection of high-risk prostate cancers in the primary biopsy setting. BJU International. E90-E97.
  • Hoem, Dag; Straume, Oddbjørn; Immervoll, Heike ; Akslen, Lars A.; Molven, Anders. 2013. Vascular proliferation is associated with survival in pancreatic ductal adenocarcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 1037-1046.
  • Ozhand, Ali; Lee, Eunjung; Wu, Anna H.; Ellingjord-Dale, Merete; Akslen, Lars A.; McKean-Cowdin, Roberta; Ursin, Giske. 2013. Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55. PLOS ONE. 8 sider.
  • Arnesen, Thomas; Glomnes, Nina; Strømsøy, Siri S.; Knappskog, Stian; Heie, Anette; Akslen, Lars A.; Grytaas, Marianne Aardal; Varhaug, Jan Erik; Gimm, Oliver; Brauckhoff, Michael. 2013. Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway. Langenbeck's archives of surgery (Print). 869-874.
  • Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. 2013. Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients. Breast Cancer Research and Treatment. 463-473.
  • Puntervoll, Hanne Eknes; Yang, Xiaohong R.; Vetti, Hildegunn Høberg; Bachmann, Ingeborg M.; Avril, Marie Françoise; Benfodda, Meriem; Catricala, Caterina; Dalle, Stéphane; Duval-Modeste, Anne B.; Ghiorzo, Paola; Grammatico, Paola; Harland, Mark; Hayward, Nicholas K.; Hu, Hui-Han; Jouary, Thomas; Martin-Denavit, Tanguy; Ozola, Aija; Palmer, Jane M.; Pastorino, Lorenza; Pjanova, Dace; Soufir, Nadem; Steine, Solrun; Stratigos, Alexander J.; Thomas, Luc; Tinat, Julie; Tsao, Hensin; Veinalde, Rūta; Tucker, Margaret A.; Bressac-de Paillerets, Brigitte B.D.; Newton-Bishop, Julia A.; Goldstein, Alisa M.; Akslen, Lars A.; Molven, Anders. 2013. Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants. Journal of Medical Genetics. 264-U82.
  • Wik, Elisabeth; Ræder, Maria B; Krakstad, Camilla; Trovik, Jone; Birkeland, Even; Høivik, Erling Andre; Mjøs, Siv; Werner, Henrica Maria Johanna; Mannelqvist, Monica; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Lack of estrogen receptor-alpha is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma. Clinical Cancer Research. 1094-1105.
  • Ræder, Maria B; Birkeland, Even; Trovik, Jone; Krakstad, Camilla; Shehata, Shyemaa; Schumacher, Steven; Zack, Travis I.; Krohn, Antje; Werner, Henrica Maria Johanna; Moody, Susan E.; Wik, Elisabeth; Stefansson, Ingunn Marie; Holst, Frederik; Øyan, Anne Margrete; Tamayo, Pablo; Mesirov, Jill P.; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Beroukhim, Rameen; Salvesen, Helga Birgitte. 2013. Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. PLOS ONE. 9 sider.
  • Trovik, Jone; Wik, Elisabeth; Werner, Henrica Maria Johanna; Krakstad, Camilla; Helland, Harald; Vandenput, Ingrid; Njølstad, Tormund Salvesen; Stefansson, Ingunn; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial. European Journal of Cancer. 3431-3441.
  • Garcia-Dios, Diego A; Lambrechts, Diether; Coenegrachts, Lieve; Vandenput, Ingrid; Capoen, An; Webb, Penelope M.; Ferguson, Kaltin; Akslen, Lars A.; Claes, Bart; Vergote, Ignace; Moerman, Philippe; Robays, Johan Van; Marcickiewicz, Janusz; Salvesen, Helga Birgitte; Spurdle, Amanda B; Amant, Frédéric. 2013. High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma. Gynecologic Oncology. 327-334.
  • Wik, Elisabeth; Birkeland, Even; Trovik, Jone; Werner, Henrica Maria Johanna; Høivik, Erling Andre; Mjøs, Siv; Krakstad, Camilla; Kusonmano, Kanthida; Mauland, Karen Klepsland; Stefansson, Ingunn Marie; Holst, Frederik; Petersen, Kjell; Øyan, Anne Margrete; Simon, Roland; Kalland, Karl-Henning; Ricketts, William; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. High phospho-stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition. Clinical Cancer Research. 2331-2341.
  • Klingen, Tor Audun; Chen, Ying; Suhrke, Pål; Stefansson, Ingunn Marie; Gundersen, Marian D.; Akslen, Lars A. 2013. Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas. Diagnostic Pathology.
  • Pedersen, Torbjørn Østvik; Blois, Anna; Xing, Zhe; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Akslen, Lars A.; Lorens, James; Leknes, Knut N.; Fristad, Inge; Mustafa, Kamal Babikeir Eln. 2013. Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs. Stem Cell Research & Therapy. 10 sider.
  • Haldorsen, Ingfrid S.; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Stefansson, Ingunn Marie; Akslen, Lars A.; Trovik, Jone; Taxt, Torfinn; Salvesen, Helga Birgitte. 2013. Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence. European Radiology. 2916-2925.
  • Catena, Raúl; Bhattacharya, Nandita; El Rayes, Tina; Wang, Suming; Choi, Hyejin; Gao, Dingcheng; Ryu, Seongho; Joshi, Natasha; Bielenberg, Diane; Lee, Sharrell B.; Haukaas, Svein Andreas; Gravdal, Karsten; Halvorsen, Ole Johan; Akslen, Lars A.; Watnick, Randolph S.; Mittal, Vivek. 2013. Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discovery. 578-589.
  • Veinalde, Rūta; Ozola, Aija; Azarjana, Kristine; Molven, Anders; Akslen, Lars A.; Donina, Simona; Proboka, Guna; Cema, Ingrida; Baginskis, Ainars; Pjanova, Dace. 2013. Analysis of Latvian familial melanoma patients shows novel variants in the noncoding regions of CDKN2A and that the CDK4 mutation R24H is a founder mutation. Melanoma research. 221-226.
  • Werner, Henrica Maria Johanna; Berg, Anna; Wik, Elisabeth; Birkeland, Even; Krakstad, Camilla; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Øyan, Anne Margrete; Akslen, Lars A.; Trovik, Jone; Salvesen, Helga Birgitte. 2013. ARID1A loss is prevalent in endometrial hyperplasia with atypia and low-grade endometrioid carcinomas. Modern Pathology. 428-434.
  • Iles, Mark M.; Law, Matthew H.; Stacey, Simon N.; Han, Jiali; Fang, Shenying; Pfeiffer, Ruth; Harland, Mark; MacGregor, Stuart; Taylor, John C.; Aben, Katja K.; Akslen, Lars A.; Avril, Marie Françoise; Azizi, Esther; Bakker, Bert; Benediktsdottir, Kristun R.; Bergman, Wilma; Scarra, Giovanna Bianchi; Brown, Kevin M.; Calista, Donato; Chaudru, Valerie; Fargnoli, Marie Concetta; Cust, Anne E.; Demenais, Florence; de Waal, Anne C.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Hopper, John L.; Ingvar, Christian; Janssen, Marjolein; Jenkins, Mark A.; Kanetsky, Peter A.; Kiemeney, Lambertus A.; Lang, Julie L.; Lathrop, G. Mark; Leachman, Sancy; Lee, Jeffrey E.; Lubiński, Jan; Mackie, Rona M.; Mann, Graham J.; Martin, Nicholas G.; Mayordomo, Jose Ignacio; Molven, Anders; Mulder, Suzanne; Nagore, Eduardo; Novakovic, Srdjan; Okamoto, Ichiro; Olafsson, Jon H.; Olsson, Håkan; Pehamberger, Hubert; Peris, Ketty; Grasa, Maria Pilar; Planelles, Dolores; Puig, Susana; Puig-Butille, Joan Anton; Randerson-Moor, Juliette; Requena, Celia; Rivoltini, Licia; Rodolfo, Monica; Santinami, Mario; Sigurgeirsson, Bardur; Snowden, Helen; Song, Fengju; Sulem, Patrick; Thorisdottir, Kristin; Tuominen, Rainer; Van Belle, Patricia; van der Stoep, Nienke; van Rossum, Michelle M.; Wei, Qingyi; Wendt, Judith; Zelenika, Diane; Zhang, Mingfeng; Landi, Maria Teresa; Thorleifsson, Gudmar; Bishop, D. Timothy; Amos, Christopher I.; Hayward, Nicholas K.; Stefansson, Kari; Bishop, Julia A. Newton; Barrett, Jennifer H. 2013. A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics. 428-432.
  • Arnes, Jarle; Stefansson, Ingunn Marie; Straume, Oddbjørn; Baak, Jan P.A.; Lønning, Per Eystein; Foulkes, William D.; Akslen, Lars A. 2012. Vascular proliferation is a prognostic factor in breast cancer. Breast Cancer Research and Treatment. 501-510.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Tumor necrosis is a prognostic factor in thick cutaneous melanoma. American Journal of Surgical Pathology. 1477-1482.
  • Straume, Oddbjørn; Shimamura, Takeshi; Lampa, Michael J.G.; Carretero, Julian; Øyan, Anne Margrete; Jia, Di; Borgman, Christa L.; Soucheray, Margaret; Downing, Sean R.; Short, Sarah M.; Kang, Soo-Young; Wang, Suoming; Chen, Liang; Collett, Karin; Bachmann, Ingeborg M.; Wong, Kwok-Kin; Shapiro, Geoffrey I.; Kalland, Karl-Henning; Folkman, Judah; Watnick, Randolph S.; Akslen, Lars A.; Naumov, George N. 2012. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 8699-8704.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Prognostic Importance of the Mitotic Marker Phosphohistone H3 in Cutaneous Nodular Melanoma. Journal of Investigative Dermatology. 1247-1252.
  • Ellingjord-Dale, Merete; Lee, Eunjung; Couto, Elisabeth; Ozhand, Ali; Qureshi, Samera Azeem; Hofvind, Solveig; Van Den Berg, David J; Akslen, Lars A.; Grotmol, Tom; Ursin, Giske. 2012. Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users. Breast Cancer Research.
  • Krüger, Kristi; Stefansson, Ingunn Marie; Collett, Karin; Arnes, Jarle; Aas, Turid; Akslen, Lars A. 2012. Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer. Breast. 1-7.
  • Helsing, Per; Nymoen, Dag Andre; Rootwelt, Helge; Vårdal, Mari H; Akslen, Lars A.; Molven, Anders; Andresen, Per Arne. 2012. MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. Genes, Chromosomes and Cancer. 654-661.
  • Krakstad, Camilla; Trovik, Jone; Wik, Elisabeth; Engelsen, Ingeborg Bøe; Werner, Henrica Maria Johanna; Birkeland, Even; Ræder, Maria B; Øyan, Anne Margrete; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2012. Loss of GPER identifies new targets for therapy among a subgroup of ER alpha-positive endometrial cancer patients with poor outcome. British Journal of Cancer. 1682-1688.
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Wik, Elisabeth; Kusonmano, Kanthida; Ræder, Maria B; Øyan, Anne Margrete; Kalland, Karl-Henning; Moses, Marsha A.; Salvesen, Helga Birgitte; Akslen, Lars A. 2012. Lipocalin 2 expression is associated with aggressive features of endometrial cancer. BMC Cancer. 7 sider.
  • Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, R; Krakstad, Camilla; Salvesen, Helga Birgitte. 2012. KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer. British Journal of Cancer. 1997-2004.
  • Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita Maria; Bathen, Tone Frost; Nalwoga, Hawa; Krüger, Kristi; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebråten, Olav; Gribbestad, Ingrid S. 2012. In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts. Journal of Magnetic Resonance Imaging. 1098-1107.
  • Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug. 2012. Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 10 sider.
  • Lindholm, Evita Maria; Kristian, Alexandr; Nalwoga, Hawa; Kruger, Kristi; Nygård, Ståle; Akslen, Lars A.; Mælandsmo, Gunhild; Engebråten, Olav. 2012. Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal- and luminal-like breast cancer xenografts. Molecular Oncology. 418-427.
  • Nygård, Yngve; Haukaas, Svein Andreas; Waage, Jo Erling Riise; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2012. Combination of real-time elastography and urine prostate cancer gene 3 (PCA3) detects more than 97 % of significant prostate cancers. Scandinavian Journal of Urology and Nephrology. 211-216.
  • Schuster, Cornelia; Eikesdal, Hans Petter; Puntervoll, Hanne Eknes; Geisler, Jürgen; Geisler, Stephanie; Heinrich, Daniel; Molven, Anders; Lønning, Per Eystein; Akslen, Lars A.; Straume, Oddbjørn. 2012. Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension. PLOS ONE. 8 sider.
  • Nalwoga, Hawa; Arnes, Jarle; Stefansson, Ingunn Marie; Wabinga, Henry; Foulkes, William D.; Akslen, Lars A. 2011. Vascular proliferation is increased in basal-like breast cancer. Breast Cancer Research and Treatment. 1063-1071.
  • Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Njølstad, Tormund Salvesen; Vandenput, Ingrid; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte; Ellstrøm Engh, Marie; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik. 2011. Stathmin Overexpression Identifies High-Risk Patients and Lymph Node Metastasis in Endometrial Cancer. Clinical Cancer Research. 3368-3377.
  • Ke, Xisong; Li, Wencheng; Hovland, Randi; Qu, Yi; Liu, Run-hui; McCormack, Emmet Martin; Thorsen, Frits Alan; Olsen, Jan Roger; Molven, Anders; Kogan-Sakin, Ira; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2011. Reprogramming of cell junction modules during stepwise epithelial to mesenchymal transition and accumulation of malignant features in vitro in a prostate cell model. Experimental Cell Research. 234-247.
  • Myklebust, Line Merethe; Akslen, Lars A.; Varhaug, Jan Erik; Lillehaug, Johan R. 2011. Receptor for Activated Protein C Kinase 1 (RACK1) Is Overexpressed in Papillary Thyroid Carcinoma. Thyroid. 1217-1225.
  • Mauland, Karen Klepsland; Trovik, Jone; Wik, Elisabeth; Ræder, Maria B; Njølstad, Tormund Salvesen; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Bjørge, Tone; Akslen, Lars A.; Salvesen, Helga Birgitte. 2011. High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer. British Journal of Cancer. 921-926.
  • Akslen, Lars A.; Straume, Oddbjørn; Geisler, Stephanie; Sørlie, Therese; Chi, Jen-Tan Ashley; Aas, Turid; Børresen-Dale, Anne-Lise ; Lønning, Per Eystein. 2011. Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer. British Journal of Cancer. 9-12.
  • Barrett, Jennifer H.; Iles, MM; Harland, M; Taylor, JC; Aitken, JF; Andresen, Per Arne; Akslen, Lars A.; Armstrong, BK; Avril, MF; Azizi, E; Bakker, B; Bergman, W; Bianchi-Scarra, G; Bressac-de Paillerets, B; Calista, D; Cannon-Albright, LA; Corda, E; Cust, AE; Debniak, T; Duffy, D; Dunning, AM; Easton, DF; Friedman, E; Galan, P; Ghiorzo, P; Giles, GG; Hansson, J; Hocevar, M; Hoiom, V; Hopper, JL; Ingvar, C; Janssen, B; Jenkins, MA; Jonsson, G; Kefford, RF; Landi, G; Landi, MT; Lang, J; Lubinski, J; Mackie, R; Malvehy, J; Martin, NG; Molven, Anders; Montgomery, GW; van Nieuwpoort, FA; Novakovic, S; Olsson, H; Pastorino, L; Puig, S; Puig-Butille, JA; Randerson-Moor, J; Snowden, H; Tuominen, R; VanBelle, P; van der Stoep, N; Whiteman, DC; Zelenika, D; Han, JL; Fang, SY; Lee, JE; Wei, QY; Lathrop, GM; Gillanders, EM; Brown, KM; Goldstein, AM; Kanetsky, PA; Mann, GJ; MacGregor, S; Elder, DE; Amos, CI; Hayward, NK; Gruis, NA; Demenais, F; Bishop, JAN; Bishop, D. Timothy. 2011. Genome-wide association study identifies three new melanoma susceptibility loci. Nature Genetics. 1108-U98.
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Bredholt, Geir; Bø, Trond Hellem; Øyan, Anne Margrete; Jonassen, Inge; Kalland, Karl-Henning; Salvesen, Helga Birgitte; Akslen, Lars A. 2011. Gene Expression Patterns Related to Vascular Invasion and Aggressive Features in Endometrial Cancer. American Journal of Pathology. 861-871.
  • Vandenput, Ingrid; Trovik, Jone; Leunen, Karin; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Moerman, Philippe; Vergote, Ignace; Salvesen, Helga Birgitte; Amant, Frédéric. 2011. Evolution in endometrial cancer evidence from an immunohistochemical study. International Journal of Gynecological Cancer. 316-322.
  • Hegen, Anja; Blois, Anna; Tiron, Crina Elena; Hellesøy, Monica; Micklem, David Robert; Nör, Jacques E; Akslen, Lars A.; Lorens, James. 2011. Efficient in vivo vascularization of tissue-engineering scaffolds. Journal of Tissue Engineering and Regenerative Medicine. E52-E62.
  • Blows, Fiona M.; Driver, Kristy E.; Schmidt, Marjanka K.; Broeks, Annegien; van Leeuwen, Fllora E.; Wesseling, Jelle; Cheang, Maggie C.U. ; Gelmon, Karen; Nielsen, Torsten O.; Blomqvist, Carl; Heikkila, Päivi; Heikkinen, Tuomas; Nevanlinna, Heli; Akslen, Lars A.; Bégin, Louis R.; Foulkes, William D.; Couch, Fergus J.; Wang, Xianshu; Cafourek, Vicky; Olson, Janet E.; Baglietto, Laura; Giles, Graham G.; Severi, Gianluca; McLean, Catriona A.; Southey, Melissa C.; Rakha, Emad A.; Green, Andrew R.; Ellis, Ian O.; Sherman, Mark E.; Lissowska, Jolanta; Anderson, William F.; Cox, Angela; Cross, Simon S.; Reed, Malcolm W.R.; Provenzano, Elena; Dawson, Sarah-Jane; Dunning, Alison M.; Humphreys, Manjeet; Easton, Douglas F.; García-Closas, Montserrat; Caldas, Carlos; Pharoah, Paul D.; Huntsman, David G. 2010. Subtyping of breast cancer by immunohistochemistry to investigate a relationship between subtype and short and long term survival: a collaborative analysis of data for 10,159 cases from 12 studies. PLoS Medicine. 12 sider.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2010. Ki-67 expression is superior to mitotic count and novel proliferation markers PHH3, MCM4 and mitosin as a prognostic factor in thick cutaneous melanoma. BMC Cancer. 15 sider.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2010. Expression of aldehyde dehydrogenase a (ALDH1) is associated with basal-like markers and features of aggressive tumors in African breast cancer. British Journal of Cancer. 369-375.
  • Gjerdrum, Christine; Tiron, Crina Elena; Høiby, Torill; Stefansson, Ingunn Marie; Haugen, Hallvard; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2010. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proceedings of the National Academy of Sciences of the United States of America. 1124-1129.
  • Rakha, Emad A.; Elsheikh, Somaia E.; Aleskandarany, Muhammed A.; Habashi, Hany O.; Green, Andrew R.; Powe, Desmond G.; El-Sayed, Maysa E.; Benhasouna, Ahmed; Brunet, Jean-Sébastien; Akslen, Lars A.; Evans, Andy J.; Blamey, Roger; Reis-Filho, Jorge S.; Foulkes, William D.; Ellis, Ian O. 2009. Triple-Negative Breast Cancer: Distinguishing between Basal and Nonbasal Subtypes. Clinical Cancer Research. 2302-2310.
  • Rostad, Kari; Hellwinkel, Olaf JC; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Øyan, Anne Margrete; Haese, Alexander; Budäus, Lars; Albrecht, Heiko; Akslen, Lars A.; Schlomm, Thorsten; Kalland, Karl-Henning. 2009. TMPRSS2:ERG fusion transcripts in urine from prostate cancer patients correlate with a less favorable prognosis. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 575-582.
  • Klingen, Tor Audun; Klaasen, Herman; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 762-767.
  • Klingen, Tor A; Klaasen, Heman; Aas, Hans; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 762-767.
  • Kang, Soo-Young; Halvorsen, Ole Johan; Gravdal, Karsten; Bhattacharya, Nandita; Lee, Jung Min; Liu, Nathan W.; Johnston, Brian T.; Johnston, Adam B.; Haukaas, Svein Andreas; Aamodt, Kristie; Yoo, Sun; Akslen, Lars A.; Watnick, Randolph S. 2009. Prosaposin inhibits tumor metastasis via paracrine and endocrine stimulation of stromal p53 and Tsp-1. Proceedings of the National Academy of Sciences of the United States of America. 12115-12120.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progression in prostate cancer. Cancer Research. 4708-4715.
  • Bhriain, Hannah Ni; Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Salvesen, Helga Birgitte; Staff, Anne Cathrine. 2009. Plasma calprotectin concentrations in women with endometrial carcinoma. Gynecologic Oncology. 491-495.
  • Bruland, Ove; Fluge, Øystein; Akslen, Lars A.; Eiken, Hans Geir; Lillehaug, Johan R.; Varhaug, Jan Erik; Knappskog, Per Morten. 2009. Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas. BMC Cancer. 425.
  • Salvesen, Helga Birgitte; Carter, Scott L.; Mannelqvist, Monica; Dutt, Amit; Getz, Gad; Stefansson, Ingunn Marie; Ræder, Maria Therese Barøy; Sos, Martin L.; Engelsen, Ingeborg Bøe; Trovik, Jone; Wik, Elisabeth; Greulich, Heidi; Bø, Trond Hellem; Jonassen, Inge; Thomas, Roman K.; Zander, Tim; Garraway, Levi A.; Øyan, Anne Margrete; Sellers, William R.; Kalland, Karl-Henning; Meyerson, Matthew; Akslen, Lars A.; Beroukhim, Rameen. 2009. Integrated genomic profiling of endometrial carcinoma associates aggressive tumors with indicators of PI3 kinase activation. Proceedings of the National Academy of Sciences of the United States of America. 4834-4839.
  • Etemadmoghadam, Dariush; deFazio, Anna; Beroukhim, Rameen; Mermel, Craig; George, Joshy; Getz, Gad; Tothill, Richard; Okamoto, Aikou; Ræder, Maria Therese Barøy; Harnett, Paul; Lade, Stephen; Akslen, Lars A.; Tinker, Anna V.; Locandro, Bianca; Alsop, Kathryn; Chiew, Yoke-Eng; Traficante, Nadia; Fereday, Sian; Johnson, Daryl; Fox, Stephen; Sellers, William R.; Urashima, Mitsuyoshi; Salvesen, Helga Birgitte; Meyerson, Matthew; Bowtell, David. 2009. Integrated Genome-Wide DNA Copy Number and Expression Analysis Identifies Distinct Mechanisms of Primary Chemoresistance in Ovarian Carcinomas. Clinical Cancer Research. 1417-1427.
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Salvesen, Helga Birgitte; Akslen, Lars A. 2009. Importance of tumour cell invasion in blood and lymphatic vasculature among patients with endometrial carcinoma. Histopathology. 174-183.
  • Pjanova, Dace; Molven, Anders; Akslen, Lars A.; Engele, Ludmila; Streinerte, Baiba; Azarjana, Kristine; Heisele, Olita. 2009. Identification of a CDK4 R24H mutation-positive melanoma family by analysis of early-onset melanoma patients in Latvia. Melanoma research. 119-122.
  • Moen, Ingrid; Øyan, Anne Margrete; Kalland, Karl-Henning; Tronstad, Karl Johan; Akslen, Lars A.; Chekenya, Martha; Sakariassen, Per Øystein; Reed, Rolf K.; Stuhr, Linda Elin Birkhaug. 2009. Hyperoxic treatment induces mesenchymal to epithelial transition in a rat adenocarcinoma model. PLOS ONE.
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Li, Wen-Cheng; Lin, Biaoyang; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Jonassen, Inge; Petersen, Kjell; Goldfinger, Naomi; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. Genome-wide profiling of histone H3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis. PLOS ONE. 14 sider.
  • Arnes, Jarle; Begin, LR; Brunet, JS; Nielsen, TO; Foulkes, WD; Akslen, Lars A.; Akslen, LA. 2009. Expression of epidermal growth factor receptor in relation to BRCA1 status, basal-like markers and prognosis in breast cancer. Journal of Clinical Pathology. 139-146.
  • Fluge, Øystein; Gravdal, K; Carlsen, Erik; Vonen, Barthold; Kjellevold, K; Refsum, S; Lilleng, R; Eide, Tor J.; Halvorsen, TB; Tveit, Kjell Magne; Otte, AP; Akslen, LA; Dahl, O. 2009. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. British Journal of Cancer. 1282-1289.
  • Mæhle, Bjørn Ove; Collett, Karin; Tretli, Steinar; Akslen, Lars A.; Grotmol, Tom. 2009. Estrogen receptor β– an independent prognostic marker in estrogen receptor α and progesterone receptor-positive breast cancer? Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 644-650.
  • Wik, Elisabeth; Trovik, Jone; Iversen, Ole-Erik; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Vestrheim, LC; Haugland, Hans K.; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting. American Journal of Obstetrics and Gynecology. 603-607.
  • Naumov, George N.; Nilsson, Monique B.; Cascone, Tina; Briggs, Alexandra; Straume, Oddbjørn; Akslen, Lars A.; Lifshits, Eugene; Byers, Lauren Averett; Xu, Li; Wu, Hua-kang; Jänne, Pasi; Kobayashi, Susumu; Halmos, Balazs; Tenen, Daniel; Tang, Xi M.; Engelman, Jeffrey; Yeap, Beow; Folkman, Judah; Johnson, Bruce E.; Heymach, John V. 2009. Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clinical Cancer Research. 3484-3494.
  • Lin, Biaoyang; Utleg, Angelita G.; Gravdal, Karsten; White, James T.; Halvorsen, Ole Johan; Lu, Wei; True, Lawrence D.; Vessella, Robert; Lange, Paul H.; Nelson, Peter S.; Hood, Leroy; Kalland, Karl-Henning; Akslen, Lars A. 2008. WDR19 expression is increased in prostate cancer compared with normal cells, but low-intensity expression in cancers is associated with shorter time to biochemical failures and local recurrence. Clinical Cancer Research. 1397-1406.
  • Bachmann, Ingeborg M.; Ladstein, Rita Grude; Straume, Oddbjørn; Naumov, GN; Akslen, Lars A. 2008. Tumor necrosis is associated with increased alphavbeta3 integrin expression and poor prognosis in nodular cutaneous melanomas. BMC Cancer. 362-372.
  • Helsing, Per; Nyrnoen, Dag André; Ariansen, Sarah; Steine, Solrun; Mæhle, Lovise; Aamdal, Steinar; Langmark, Frøydis; Loeb, Mitchell; Akslen, Lars A.; Molven, Anders; Andresen, Per Arild Kjølseth. 2008. Population-based prevalence of CDKN2A and CDK4 mutations in patients with multiple primary melanomas. Genes, Chromosomes and Cancer. 175-184.
  • Akslen, Lars A.; Puntervoll, Hanne Eknes; Bachmann, Ingeborg M.; Straume, Oddbjørn; Vuhahula, Edda; Kumar, Rajiv; Molven, Anders. 2008. Mutation analysis of the EGFR-NRAS-BRAF pathway in melanomas from black Africans and other subgroups of cutaneous melanoma. Melanoma research. 29-35.
  • Engelsen, Ingeborg Bøe; Mannelqvist, Monica; Stefansson, Ingunn Marie; Carter, Scott L.; Beroukhim, Rameen; Øyan, Anne Margrete; Otte, Ariel P.; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2008. Low BMI-1 expression is associated with an activated BMI-1-driven signature, vascular invasion, and hormone receptor loss in endometrial carcinoma. British Journal of Cancer. 1662-1669.
  • Bachmann, Ingeborg M.; Puntervoll, Hanne Eknes; Otte, Arie P.; Akslen, Lars A. 2008. Loss of BMI-1 expression is associated with clinical progress of malignant melanoma. Modern Pathology. 583-590.
  • Arnes, Jarle; Collett, Karin; Akslen, Lars A. 2008. Lesson of the Month - Independent prognostic value of the basal-like phenotype of breast cancer and associations with EGFR and candidate stem cell marker BMI-1. Histopathology. 370-380.
  • Borkamo, Erling Dahl; Fluge, Øystein; Mella, Olav; Akslen, Lars A.; Bruland, Ove; Dahl, Olav. 2008. Hyperthermia improves the antitumour effect of metronomic cyclophosphamide in a rat transplantable brain tumour. Radiotherapy and Oncology. 435-442.
  • Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Beroukhim, Rameen; Sellers, William R.; Meyerson, Matthew; Akslen, Lars A.; Salvesen, Helga. 2008. HER-2/neu expression is associated with high tumor cell proliferation and aggressive phenotype in a population based patient series of endometrial carcinomas. International Journal of Oncology. 307-316.
  • Engelsen, Ingeborg Bøe; Stefansson, IM; Akslen, Lars A.; Salvesen, Helga Birgitte. 2008. GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival. American Journal of Obstetrics and Gynecology. e 1-7.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2008. Expression of EGFR and c-kit is associated with the basal-like phenotype in breast carcinomas of African women. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 515-525.
  • Ke, Xisong; Qu, Yi; Goldfinger, Naomi; Rostad, Kari; Hovland, Randi; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Epithelial to Mesenchymal Transition of a Primary Prostate Cell Line with Switches of Cell Adhesion Modules but without Malignant Transformation. PLOS ONE.
  • Dutt, Amit; Salvesen, Helga; Chent, Tzu-Hsiu; Ramos, Alex H.; Onofrio, Robert C.; Hatton, Charlie; Nicoletti, Richard; Winckler, Wendy; Grewal, Rupinder; Hanna, Megan; Wyhs, Nicolas; Ziaugra, Liuda; Richter, Daniel J.; Trovik, Jone; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Fennell, Tim; Cibulskis, Kristian; Zody, Michael C.; Akslen, Lars A.; Gabriel, Stacey; Wong, Kwok-Kin; Sellers, William R.; Meyerson, Matthew; Greulich, Heidi. 2008. Drug-sensitive FGFR2 mutations in endometrial carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 8713-8717.
  • Tischkowitz, Marc; Brunet, Jean-Sébastien; Bégin, Louis R.; Huntsman, David G.; Cheang, Maggie C.U. ; Akslen, Lars A.; Nielsen, Torsten O.; Foulkes, William D. 2007. Use of immunohistochemical markers can refine prognosis in triple negative breast cancer. BMC Cancer. 11 sider.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Puntervoll, Hanne Eknes; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2007. Increased expression of sim2-s protein is a novel marker of aggressive prostate cancer. Clinical Cancer Research. 892-897.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2007. Frequency of the basal-like phenotype in African breast cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 1391-1399.
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2007. ERG upregulation and related ETS transcription factors in prostate cancer. International Journal of Oncology. 19-32.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. A Switch from E-Cadherin to N-Cadherin Expression Indicates Epithelial to Mesenchymal Transition and Is of Strong and Independent Importance for the Progress of Prostate Cancer. Clinical Cancer Research. 7003-7011.
  • Naumov, George N.; Akslen, Lars A.; Folkman, Judah. 2006. Role of angiogenesis in human tumor dormancy - Animal models of the angiogenic switch. Cell Cycle. 1779-1787.
  • Sørlie, Therese; Perou, Charles M.; Fan, Cheng; Geisler, Stephanie; Aas, Turid; Nobel, Andrew; Anker, Gun; Akslen, Lars A.; Botstein, David; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 2006. Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer. Molecular Cancer Therapeutics. 2914-2918.
  • Bachmann, Ingeborg Margrethe; Halvorsen, Ole Johan; Collett, Karin; Stefansson, Ingunn Marie; Straume, Oddbjørn; Haukaas, Svein Andreas; Salvesen, Helga; Otte, Arie P.; Akslen, Lars A. 2006. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. Journal of Clinical Oncology. 268-273.
  • Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Skaane, P; Urdal, Petter; Berghagen, Hege; Jensen, Maianne; Kristiansen, Lena; Moen, Cecilie; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Sauer, Toril; Akslen, Lars A; Schlichting, Ellen; Børresen-Dale, Anne-Lise ; Lönneborg, Anders. 2005. Early detection of brest cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. R634-R644.
  • Akslen, Lars A.; Angelini, Sabrina; Straume, Oddbjørn; Molven, Anders; Bachmann, Ingeborg; Hemminki, Kari; Kumar, Rajiv. 2005. BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival. Journal of Investigative Dermatology. 312-317.
  • Molven, Anders; Grimstvedt, Magne B.; Steine, Solrun; Harland, Mark; Avril, Marie-Françoise; Hayward, Nicholas K.; Akslen, Lars A. 2005. A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation. Genes, Chromosomes and Cancer. 10-18.
  • Salvesen, Helga Birgitte; Akslen, Lars A. 2002. Molecular pathogenesis and prognostic factors in endometrial carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 673-689.
  • Fluge, Øystein; Haugen, Dagny R. Faksvåg; Akslen, Lars A.; Marstad, Anne; Santoro, Massimo; Fusco, Alfredo; Varhaug, Jan Erik; Lillehaug, Johan. 2001. Expression and alternative splicing of c-ret RNA in papillary thyroid carcinomas. Oncogene. 885-892.
  • Perou, CM; Sørlie, T; Eisen, MB; van de Rijn, M; Jeffrey, SS; Rees, CA; Pollack, JR; Ross, DT; Johnsen, H; Akslen, Lars A.; Fluge, Øystein; Pergamenschikov, A; Williams, C; Zhu, SX; Lønning, Per Eystein; Børresen-Dale, Anne-Lise; Brown, PO; Botstein, D. 2000. Molecular portraits of human breast tumours. Nature. 747-52.
  • Paulsen, Trond H; Aas, Turid; Børresen, Anne-Lise; Varhaug, Jan Erik; Lønning, Per Eystein; Akslen, Lars A. 1997. Angiogenesis does not predict clinical response to doxorubicin monotherapy in patients with locally advanced breast cancer. International Journal of Cancer. 138-140.
  • Akslen, Lars A. 1996. Thyroid carcinomas with tall-cell and columnar-cell features (letter). Current Diagnostic Pathology. 67.
  • Aas, T; Børresen, A-L; Geisler, D; Smidth-Sørensen, B; Johnsen, H; Varhaug, Jan Erik; Akslen, Lars A.; Lønning, Per Eystein. 1996. Spesific TP53 gene mutations are associated with de novo resistance to doxorubicin in breast cancer patients. Nature Medicine. 811-814.
  • Aas, T; Børresen, A-L; Geisler, Stephanie; Johnsen, H; Varhaug, Jan Erik; Akslen, Lars A.; Lønning, PE. 1996. Relationship between mutations in the TP53 gene and De Novo resistance and early relapse following treatment with doxorubicin in patients with breast cancer. Nature Medicine. 811-814.
  • Aas, Turid; Geisler, Stephanie; Paulsen, Trond H; Børresen, Anne-Lise; Varhaug, Jan Erik; Lønning, Per Eystein; Akslen, Lars A. 1996. Primary systemic treatment with weekly doxorubicin monotherapy in women with locally advanced breast cancer; Clinical experience and parameters predicting outcome. Acta Oncologica. 5-8.
  • Ness, G. O.; Bjerkvig, Rolf; Akslen, Lars A.; Lillehaug, Johan; Varhaug, Jan Erik. 1996. Primary organ-culture of non neoplastic and neoplastic thyroid tissue as multicellular spheroids. International Journal of Oncology. 1071-1078.
  • Straume, O; Akslen, Lars A. 1996. Independent prognostic importance of vascular invasion in nodular melanomas. Cancer. 1211-1219.
  • Akslen, Lars A. 1996. Incidence of thyroid cancer in New Caledonia, South Pacific, during 1985-1992 (letter). American Journal of Epidemiology. 1174.
  • Haugen, Dagny R. Faksvåg; Akslen, Lars A.; Varhaug, Jan Erik; Lillehaug, Johan. 1996. Expression of c-erbB-3 and c-erbB-4 proteins in papillary thyroid carcinomas. Cancer Research. 1184-1188.
  • Ness, GO; Haugen, Dagny F. Faksvåg; Varhaug, Jan Erik; Akslen, Lars A.; Lillehaug, Johan. 1996. Cytoplasmatic localization of EGF receptor in papillary thyroid carcinomas: Association with the 150-kDa receptor forms. International Journal of Cancer. 161-167.
  • Akslen, Lars A.; Mæhle, B.O.; Varhaug, Jan Erik. 1996. Aggressive thyroid carcinoma with predominant cribriform growth pattern. Pathology, Research and Practice.
  • Salvesen, Helga; Njølstad, Pål Rasmus; Akslen, Lars A.; Albrektsen, Grethe; Viste, Asgaut; Søreide, Odd; Varhaug, Jan Erik. 1992. Thyroid carcinoma. Results from surgical treatment in 211 consecutive patients. European Journal of Surgery. 521-526.
  • Akslen, Lars A.; Nilssen, S.; Kvåle, Gunnar. 1992. Reproductive factors and risk of thyroid cancer. A prospective study of 63090 women from Norway. British Journal of Cancer. 772-774.
  • Salvesen, Helga; Njølstad, Pål Rasmus; Akslen, Lars A.; Albrektsen, Grethe; Søreide, Odd; Varhaug, Jan Erik. 1992. Disease free and cause specific survival in patients with papillary thyroid carcinoma. A multifactorial analysis. European Journal of Surgery. 583-589.
  • Småland, Rune; Akslen, Lars A.; Tønder, Bjarne; Mehus, A.; Lote, K.; Albrektsen, Grethe. 1991. Radical radiation treatment of invasive and locally advanced bladder carcinoma in elderly patients. British Journal of Urology. 61-69.
  • Akslen, Lars A.; Myking, Andreas O; Mørkve, Odd; Gulsvik, Amund; Raithel, H. J.; Schaller, K. H. 1990. Increased content of chronium and nickel in lung tissues patients with bronchial carcinoma. Pathology, Research and Practice. 717-722.
  • Akslen, Lars A.; Andersen, Knut-Jan; Bjerkvig, Rolf. 1988. Characteristics of Human and Rat Glioma Cells Grown in a Defined Medium. Anticancer Research. 797-804.
Vitenskapelig foredrag
  • Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe. 2016. Molecular subtypes of breast cancer: long-term incidence trends and prognostic differences.
  • Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. 2016. FGD5 amplification in breast cancer patients is associated with tumour proliferation and a poorer prognosis.
  • Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. 2013. Molekylære subtyper og overlevelse ved brystkreft.
  • Engstrøm, Monica J; Opdahl, Signe; Hansen, Åse Kristin Skain; Romundstad, Pål Richard; Vatten, Lars Johan; Akslen, Lars A.; Hagen, Anne Irene; Haugen, Olav Anton; Bofin, Anna M. 2013. Molekylære subtyper og overlevelse ved brystkreft.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Haugland, Hans Kristian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2012. Multimodal imaging for suspected recurrent differentiated thyroid cancer (DTC): FDG-PET-CT, I-131-SPECT-CT, ultrasound (US) and US-guided fine needle biopsy (FNB).
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2011. Multimodal imaging for diagnosis and treatment of recurrent differentiated thyroid cancer (DTC)FDG-PET-CT, contrast-enhanced CT (CE-CT), I-131-SPECT-CT, ultrasound (US) and US-guided fine needle biopsy (FNB).
  • Huuse, Else Marie; Moestue, Siver Andreas; Bathen, Tone Frost; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebråten, Olav; Gribbestad, Ingrid S. 2011. In vivo Dynamic Contrast Enhanced MRI & Histopathological Assessment of Tumor Angiogenesis in Luminal-like and Basal-like Breast Cancer Xenografts.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2011. FDG-PET-CT, I-131-SPECT-CT, ultrasound (US) and US-guided fine needle biopsy (FNB) for recurrent differentiated thyroid cancer (DTC).
  • Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Akslen, Lars A.; Engebråten, Olav; Mælandsmo, Gunhild; Gribbestad, Ingrid S. 2011. Early vascular response to bevacizumab treatment measured by DCE-MRI in breast cancer xenografts.
  • Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Engebråten, Olav; Akslen, Lars A.; Mælandsmo, Gunhild; Gribbestad, Ingrid S. 2011. DCE-MRI for early therapy monitoring of anti-angiogenic therapy.
  • Nygård, Yngve; Waage, Jo Erling Riise; Halvorsen, Ole Johan; Gravdal, Karsten; Akslen, Lars A.; Frugård, Jannicke; Haukaas, Svein Andreas; Beisland, Christian. 2010. Real time elastografi ved cancer prostatae.
  • Nygård, Yngve; Halvorsen, Ole Johan; Gravdal, Karsten; Akslen, Lars A.; Frugård, Jannicke; Haukaas, Svein Andreas; Beisland, Christian. 2010. Preliminære resultater av PCA3 måling i urin hos pasienter med cancer prostatae.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2010. Multimodal imaging of differentiated thyroid cancer: FDG-PET-CT, I-131-SPECT-CT and ultrasound.
  • Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita; Bathen, Tone Frost; Nalvoga, Hawa; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebraaten, Olav; Gribbestad, Ingrid S. 2010. In vivo magnetic resonance imaging and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts.
  • Reisæter, Lars Anders; Nygård, Yngve; Halvorsen, Ole Johan; Gravdal, Karsten; Rawal, Ravi; Akslen, Lars A.; Haukaas, Svein Andreas; Rørvik, Jarle; Beisland, Christian. 2010. Er preoperativ MR-prostata nyttig for å avklare korrekt T-stadium forut for kirurgi?
  • Reisæter, Lars Anders; Wold, Tor; Haukaas, Svein Andreas; Rørvik, Jarle; Halvorsen, Ole Johan; Akslen, Lars A.; Beisland, Christian. 2010. Er MR-prostata nyttig for å avklare videre oppfølgningsbehov hos pasienter med 2 eller flere negative biopsiserier?
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Li, Wencheng; Lin, Biaoyang; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Jonassen, Inge; Petersen, Kjell; Goldfinger, Naomi; Rotter, Varder; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. Genome-wide profiling of histone H3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.
  • Ke, Xisong; Li, Wencheng; Qu, Yi; Hovland, Randi; Rostad, Kari; Thorsen, Frits Alan; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. EMT Promotes Malignant Transformation of Prostate Epithelial Cells in Culture.
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Goldfinger, Naomi; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Polycomb group target genes and bivalent H3K4 & K27me3 modifications in human embryonic cells were enriched among dysregulated genes in prostate cancer.
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Epithelial to mesenchymal transition of a primary, immortalized prostate cell line is associated with gene expression switches of entire cell attachment modules.
  • Ke, Xisong; Øyan, Anne Margrete; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2007. Functional oncogenomics and epigenomics analysis of prostate cancer.
  • Rostad, Kari; Schlomm, Thorsten; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Øyan, Anne Margrete; Ke, Xisong; Olsen, Sue; Hellwinkel, Olaf JC; Akslen, Lars A.; Kalland, Karl-Henning. 2007. Detection of TMPRSS2:ERG translocations in the urine of prostate cancer patients and identification of ERG target genes.
  • Kalland, Karl-Henning; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2006. Global gene expression analysis of transcription factors in prostate cancer and cell lines.
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2006. ERG upregulation and related transcription factors in prostate cancer.
  • Kalland, Karl-Henning; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Rostad, Kari; Olsen, Sue; Haukaas, Svein Andreas; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Hood, Leroy; Akslen, Lars A. 2004. Gene expression profiling in prostate cancer refined by pairwise comparisons of cDNA microarrays from benign and malignant tissue.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Lin, Biaoyang; Hood, Leroy; Olsen, Sue; Haukaas, Svein Andreas; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2004. Gene expression profiles in prostate cancer: identification of upregulated SIM2 gene validated in archival tissue, relation to histological grading and prognosis.
  • Molven, Anders; Immervold, H; Kugarajh, K; Steine, Solrun; Hoem, Dag; Straume, Oddbjørn; Akslen, Lars A. 2003. Mutation analysis of the RAS-RAF pathway in pancreatic adenocarcinomas and malignant melanomas.
  • Kalland, Karl-Henning; Halvorsen, Ole J.; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Rostad, Kari; Haukaas, Sven; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Jonasen, Inge; Akslen, Lars A.; Hood, Leroy. 2003. Global analysis of gene expression and regulatory patterns in urogenital tumours using DNA microarrays.
  • Kalland, Karl-Henning; Øyan, Anne Margrete; Akslen, Lars A.; Halvorsen, Ole Johan; Bakke, August; Haukaas, Svein Andreas; Bruserud, Øystein; Gjertsen, Bjørn Tore; Ulvestad, Elling; Hellem Bø, Trond; Jonassen, Inge; Hood, Leroy; Lin, Biaoyang; Dimitrov, Krassen; Marzolf, Bruz. 2003. Global analysis of gene expression and regulatory patterns in cancer.
  • Halvorsen, Ole Johan; Øyan, Anne Margrete; Hellem Bø, Trond; Olsen, Sue; Rostad, Kari; Haukaas, Svein Andreas; Bakke, August M; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Gene expression profiling in prostate cancer: cluster analysis and association with tumor differentation.
  • Halvorsen, Ole J.; Øyan, A M; Bø, TH; Olsen, S; Rostad, K; Haukaas, Sven; Bakke, August; Marzolf, B; Dimitrov, K; Lin, B; Jonassen, Inge; Hood, L; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Gene expression profiling in prostate cancer: Cluster analysis and association with tumor differentiation.
  • Halvorsen, Ole J.; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Rostad, Kari; Haukaas, Sven; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Jonasen, Inge; Hood, Leroy; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Gene expression profiling in prostate cancer.
  • Kalland, Karl-Henning; Akslen, Lars A.; Halvorsen, Ole J.; Øyan, A M; Bakke, August; Haukaas, Sven; Bruserud, Øystein; Gjertsen, BT; Ulvestad, Elling; Bø, TH; Jonassen, Inge; Hood, L; Lin, B; Dimitrov, K; Marzolf, B. 2003. DNA microarray studies of human cancer - pitfalls and outlook.
  • Olsen, Sue; Bø, Trond Hellem; Rostad, Kari; Halvorsen, Ole J.; Øyan, Anne Margrete; Haukaas, Sven; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Hood, Leroy; Jonasen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Comparison of DNA microarray and real time quantitative PCR for quantitation of gene expression of selected genes in prostate cancer.
  • Opsahl, EM; Aas, Turid; Paulsen, Trond Harder; Anker, G; Akslen, Lars A.; Eide, J; Varhaug, Jan Erik. 2002. Cancer mammae behandlet med brystbevarende kirurgi ved Haukeland sykehus 1984-1995.
  • Halvorsen, Ole J.; Haukaas, Sven; Høisæter, Per Åge; Akslen, Lars A. 2001. Prognostisk betydning av angiogenese (microvessel density - MVD) og proliferasjonsmarkøren Ki-67 ved lokalisert prostatacencer.
  • Halvorsen, OJ; Haukaas, Svein Andreas; Høisæter, PÅ; Akslen, Lars A. 1999. Prognostic importance of microvessel density (MVD) in clinically localized prostate cancer.
  • Halvorsen, OJ; Haukaas, Svein Andreas; Høisæter, PÅ; Akslen, Lars A. 1998. Prognostic importance of microvessel density (MVD) in clinically localized prostate cancer.
  • Varhaug, Jan Erik; Boman, Helge; Akslen, Lars A. 1998. Profylaktisk thyroidectomi hos barn - initial erfaring.
  • Hove, LM; Akslen, Lars A. 1998. Malignt melanom på hender.
  • Hove, LM; Akslen, Lars A. 1998. Malignant melanoma of the hand. A 25-year clinico-pathological study.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1997. Independent prognostic importance of microvessel density in endometrial carcinoma. [poster].
  • Rotevatn, S.; Akslen, Lars A.; Bjelke, Erik. 1989. Mortality form ischemic heart disease related to life-style differences among Norwegian men (Abstract).
Vitenskapelig antologi/Konferanseserie
  • Akslen, Lars A.; Watnick, Randolph S. 2017. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Springer.
Sammendrag/abstract
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and mitotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Modern Pathology. 50A-50A.
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and Mimtotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Laboratory Investigation. 50A-50A.
  • Tangen, Ingvild Løberg; Krakstad, Camilla; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Gilfillan, Siv ; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Hurtado, A; Salvesen, Helga Birgitte. 2013. FOXA1 LOSS IN ENDOMETRIAL CANCER IS ASSOCIATED WITH POOR PROGNOSIS AND ER ALPHA LOSS. International Journal of Gynecological Cancer. 1 sider.
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2012. Prognostic impact of proliferation markers Ki-67, PHH3 and mitotic count in breast carcinomas. Virchows Archiv. S5-S5.
  • Moestue, Siver Andreas; Flatabø, Silje; Huuse, Else Marie; Lindholm, Evita Maria; Engebraaten, Olav; Maelandsmo, Gunnhild M; Akslen, Lars A.; Gribbestad, Ingrid S. 2012. Metabolic Responses to VEGF Inhibition in Patient-derived Breast Cancer Xenografts. European Journal of Cancer. S32-S32.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2012. Expression of hypoxia-inducible factor-1a and associations with vascular endothelial growth factor expression, high microvessel density and features of aggressive tumors in African breast cancer. Virchows Archiv. S249-S249.
  • Wik, Elisabeth; Rader, Maria; Krakstad, Camilla; Trovik, Jone; Erling, Hoivik; Mjøs, Siv; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2012. Estrogen receptor a loss in endometrial carcinoma is associated with epithelial-to-mesenchymal transition and a potential for PI3Kinase inhibition. Virchows Archiv. S18-S18.
  • Tiron, Crina Elena; Gjerdrum, Christine; Høiby, Torill; Maugen, Hallvard; Stefansson, Ingunn Marie; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2011. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Clinical and Experimental Metastasis. 234-235.
  • Stefansson, Ingunn Marie; Mannelquist, M; Salvesen, HB; Akslen, Lars A. 2010. Prognostic importance of vascular proliferation and tumor cell invasion in blood and lymphatic vessels in endometrial carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 248-248.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2010. Multimodal imaging of differentiated thyroid cancer: FDG-PET-CT, I-131-SPECT-CT and ultrasound [Abstract]. European Journal of Nuclear Medicine and Molecular Imaging. S291-S291.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progress in prostate cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 233-233.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2008. Vascular proliferation by Nestin/Ki-67 is a novel predictor of the clinical progress of prostate cancer. Histopathology. 276-277.
  • Arnes, Jarle; Foulkes, William D.; Akslen, Lars A. 2008. Candidate stem cell marker ALDH1 expression and relationship with BRCA-mutations and basal-like differentiation in breast carcinoma. Histopathology. 25-25.
  • Bachmann, Ingeborg M.; Eknes, HE; Otte, Ariel P.; Akslen, Lars A. 2007. Loss of BMI-1 expression is associated with the clinical progress of malignant melanoma. Virchows Archiv. 452-452.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. Epithelial to mesenchymal transition is of strong prognostic importance in prostate cancer. Virchows Archiv. 344-344.
  • Nalwoga, H; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2007. Basal-like phenotype is frequent in invasive breast carcinoma from Ugandan Africans and is strongly associated with a high expression of EGFR/c-Kit and features of aggressive tumors. Virchows Archiv. 137-137.
  • Kalland, Karl-Henning; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2006. Global gene expression analysis of transcription factors in prostate cancer and cell lines. International Journal of Molecular Medicine. S27.
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Ulvestad, Elling; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2006. ERG upregulation in relation to other transcription factors in prostate cancer. NBS-nytt. 72.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2005. Single-minded 2 homolog gene is overexpressed in prostate cancer. Virchows Archiv. 432-432.
  • Kalland, Karl-Henning; Halvorsen, Ole Johan; Rostad, Kari; Mannelqvist, Monica; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2005. Overexpression of ERG and SIM2 transcription factors in prostate cancer. International Journal of Molecular Medicine. S76-S76.
Vitenskapelig oversiktsartikkel/review
  • Geisler, Jürgen; Bachmann, Ingeborg M.; Nyakas, Marta Sølvi; Helsing, Per; Fjøsne, Hans E.; Mæhle, Lovise Olaug; Aamdal, Steinar; Eide, Nils; Svendsen, Henrik Løvendahl; Straume, Oddbjørn; Robsahm, Trude Eid; Dolven-Jacobsen, Kari ; Akslen, Lars A. 2013. Malignt melanom – diagnostikk, behandling og oppfølging i Norge. 2154-2159.
  • Engelsen, Ingeborg Bøe; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Biologic markers in endometrial cancer treatment. 693-707.
  • Naumov, George N.; Folkman, Judah; Straume, Oddbjørn; Akslen, Lars A. 2008. Tumor-vascular interactions and tumor dormancy. 569-585.

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