Hjem
Lars A. Akslens bilde

Lars A. Akslen

Professor, Leder for CCBIO
  • E-postLars.Akslen@uib.no
  • Telefon+47 55 97 31 82
  • Besøksadresse
    Patologisk avdeling, Sentralblokka 2 etg., Haukeland Universitetssjukehus (HUS)
    evt. CCBIO, Sentralblokka 2 etg., HUS
  • Postadresse
    Postboks 7804
    5020 Bergen

Akslen er en sertifisert spesialist i kirurgisk patologi og leder forskningsgruppen Tumor Biology Research Group (etablert i 1995) ved Klinisk Institutt 1, Universitetet i Bergen. Siden 2013 har Akslen vært senterleder for Centre for Cancer Biomarkers CCBIO. Akslens gruppe og CCBIO arbeider med translasjonell kreftforskning med fokus på nye kreftmarkører og målrettet behandling og særlig mekanismer knyttet til hvordan kreftceller påvirkes av mikromiljøet i svulstene, og den betydning dette har for kreftspredning og dårlig prognose. Gruppen har prosjekter på ulike kreftformer, som brystkreft, ondartet melanom, prostatakreft og gynekologisk kreft. Gruppen kombinerer studier av humane tumorprøver med eksperimentelle celle- og dyremodeller. Det overordnede målet er å finne nye biomarkører som kan hjelpe oss til å forutse hvordan aggressive svulster vil utvikle seg og dermed bedre kunne skreddersy behandling.

Vitenskapelig artikkel
  • Hofvind, Solveig; Holen, åsne Sørlien; Roman, Martha; Sebuødegård, Sofie; Puig-Vives, M; Akslen, Lars A. 2016. Mode of detection: an independent prognostic factor for women with breast cancer. Journal of Medical Screening. 89-97.
  • Nygård, Yngve; Haukaas, Svein Andreas; Eide, Geir Egil; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2015. Prostate cancer antigen-3 (PCA3) and PCA3-based nomograms in the diagnosis of prostate cancer: an external validation of Hansen's nomogram on a Norwegian cohort. Scandinavian journal of urology. 8-15.
  • Kraby, Maria Ryssdal; Krüger, Kristi; Opdahl, Signe; Vatten, Lars Johan; Akslen, Lars A.; Bofin, Anna M. 2015. Microvascular proliferation in luminal A and basal-like breast cancer subtypes. Journal of Clinical Pathology. 891-897.
  • Ahmed, Lavina; Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Micklem, David Robert; Akslen, Lars A. 2015. Increased tumor cell expression of Axl is a marker of aggressive features in breast cancer among African women. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 688-696.
  • Stefansson, Ingunn; Ræder, Maria B; Wik, Elisabeth; Mannelqvist, Monica; Kusonmano, Kanthida; Knutsvik, Gøril; Haldorsen, Ingfrid S.; Trovik, Jone; Øyan, Anne Margrete; Kalland, Karl-Henning; Staff, Anne Cathrine; Salvesen, Helga; Akslen, Lars A. 2015. Increased angiogenesis is associated with a 32-gene expression signature and 6p21 amplification in aggressive endometrial cancer. OncoTarget. 10634-10645.
  • Barrett, Jennifer H.; Taylor, John C.; Bright, C; Harland, Mark; Dunning, Alison M; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brossard, Myriam; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Molven, Anders; Novakovic, Srdjan; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; van der Stoep, Nienke; van Doorn, Remco; van Workum, Wilberg; Goldstein, Alisa M.; Kanetsky, Peter A.; Pharoah, Paul D.P.; Demenais, Florence; Hayward, Nicholas K.; Bishop, Julia A. Newton; Bishop, D. Timothy; Iles, Mark M. 2015. Fine mapping of genetic susceptibility loci for melanoma reveals a mixture of single variant and multiple variant regions. International Journal of Cancer. 1351-1360.
  • Reisæter, Lars Anders Rokne; Fütterer, Jurgen; Halvorsen, Ole Johan; Nygård, Yngve; Biermann, Martin; Andersen, Erling; Gravdal, Karsten; Haukaas, Svein Andreas; Monssen, Jan Anker; Huisman, Henkjan J; Akslen, Lars A.; Beisland, Christian; Rørvik, Jarle. 2015. 1.5-T multiparametric MRI using PI-RADS: a region by region analysis to localize the index-tumor of prostate cancer in patients undergoing prostatectomy. Acta Radiologica. 500-511.
  • Iles, Mark M.; Bishop, D. Timothy; Taylor, John C.; Hayward, Nicholas K.; Brossard, Myriam; Cust, Anne E.; Dunning, Alison M.; Lee, Jeffrey E.; Moses, Eric K.; Akslen, Lars A.; Andresen, Per Arne; Avril, Marie-Francoise; Azizi, Esther; Scarra, Giovanna Bianchi; Brown, Kevin M.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Harland, Mark; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Ingvar, Christian; Kanetsky, Peter A.; Landi, Maria Teresa; Lang, Julie L.; Lathrop, G. Mark; Lubinski, Jan; Mackie, Rona M.; Martin, Nicholas G.; Molven, Anders; Montgomery, Grant W.; Novakovic, Srdian; Olsson, Håkan; Puig, Susana; Puig-Butille, Joan Anton; Radford-Smith, Graham L.; Randerson-Moor, Juliette; Study Group, SDH; van der Stoep, Nienke; van Doorn, Remco; Whiteman, David C.; MacGregor, Stuart; Pooley, Karen A.; Ward, Sarah V.; Mann, Graham J.; Amos, Christopher I.; Pharoah, Paul D.P.; Demenais, Florence; Law, Matthew H.; Bishop, Julia A. Newton; Barrett, Jennifer H. 2014. The effect on melanoma risk of genes previously associated with telomere length. Journal of the National Cancer Institute.
  • Tangen, Ingvild Løberg; Krakstad, Camilla; Halle, Mari Kyllesø; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Rodriguez, Antoni Hurtado; Salvesen, Helga Birgitte. 2014. Switch in FOXA1 status associates with endometrial cancer progression. PLOS ONE.
  • Werner, Henrica Maria Johanna; Trovik, Jone; Halle, Mari Kyllesø; Wik, Elisabeth; Akslen, Lars A.; Birkeland, Even; Bredholt, Therese; Tangen, Ingvild Løberg; Krakstad, Camilla; Salvesen, Helga Birgitte. 2014. Stathmin Protein Level, a Potential Peredictive Marker for Taxane Treatment Response in Endometrial Cancer. PLOS ONE.
  • Rogers, Michael S.; Novak, Katherine; Zurakowski, David; Cryan, Lorna M.; Blois, Anna; Lifshits, Eugene; Bø, Trond; Øyan, Anne Margrete; Bender, Elise R.; Lampa, Michael; Kang, Soo-Young; Naxerova, Kamila; Kalland, Karl-Henning; Straume, Oddbjørn; Akslen, Lars A.; Watnick, Randolph S.; Folkman, Judah; Naumov, George N. 2014. Spontaneous reversion of the angiogenic phenotype to a nonangiogenic and dormant state in human tumors. Molecular Cancer Research. 754-764.
  • Shahrabi-Farahani, Shokoufeh; Wang, Lili; Zwaans, Bernadette MM; Santana, Jeans M; Shimizu, Akio; Takashima, Seiji; Kreuter, Michael; Coultas, Leigh; D'Amore, Patricia A; Arbeit, Jeffrey M.; Akslen, Lars A.; Bielenberg, Diane R. 2014. Neuropilin 1 expression correlates with differentiation status of epidermal cells and cutaneous squamous cell carcinomas. Laboratory Investigation. 752-765.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2014. Nestin expression is associated with aggressive cutaneous melanoma of the nodular type. Modern Pathology. 396-401.
  • Mackay, Helen; Eisenhauer, Elizabeth A.; Kamel-Reid, Suzanne; Tsao, Ming-Sound; Clarke, Blaise; Karakasis, Katherine; Werner, Henrica Maria Johanna; Trovik, Jone; Akslen, Lars A.; Salvesen, Helga Birgitte; Dongsheng, Tu; Oza, Amit M. 2014. Molecular determinants of outcome with mammalian target of rapamycin inhibition in endometrial cancer. Cancer. 603-610.
  • Ojesina, Akinyemi; Lichtenstein, Lee; Freeman, Samuel S.; Pedamallu, Chandra Sekhar ; Imaz-Rosshandler, I; Pugh, Trevor J.; Cherniack, Andrew D.; Ambrogio, Lauren; Cibulskis, Kristian; Bertelsen, Bjørn; Romero-Cordoba, S; Treviño, Victor; Vazquez-Santillan, K; Guadarrama, Alberto Salido; Wright, Alexi A.; Rosenberg, Mara W.; Duke, Fujiko; Kaplan, Bethany; Wang, Rui; Nickerson, Elizabeth; Walline, Heather M; Lawrence, Michael S.; Stewart, Chip; Carter, Scott L.; McKenna, Aaron; Rodriguez-Sanchez, Iram P.; Espinosa-Castilla, Magali; Woie, Kathrine; Bjørge, Line; Wik, Elisabeth; Halle, Mari Kyllesø; Høivik, Erling Andre; Krakstad, Camilla; Gabiño, Nayeli Belem; Gómez-Macías, Gabriela; Valdez-Chapa, Lezmes D.; Garza-Rodríguez, Maria Lourdes; Maytorena, German; Vazquez, Jorge; Rodea, Carlos; Cravioto, Adrian; Cortes, Maria L.; Greulich, Heidi; Crum, Christopher P.; Neuberg, Donna S.; Hidalgo-Miranda, Alfredo; Escareno, Claudia Rangel; Akslen, Lars A.; Carey, Thomas E.; Vintermyr, Olav Karsten; Gabriel, Stacey B.; Barrera-Saldana, Hugo A.; Melendez-Zajgla, Jorge; Getz, Gad; Salvesen, Helga Birgitte; Meyerson, Matthew. 2014. Landscape of genomic alterations in cervical carcinomas. Nature. 371-375.
  • Haldorsen, Ingfrid S.; Stefansson, Ingunn; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Trovik, Jone; Taxt, Torfinn; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Increased microvascular proliferation is negatively correlated to tumour blood flow and is associated with unfavourable outcome in endometrial carcinomas. British Journal of Cancer. 107-114.
  • Lia, Wenliang; Ai, Nanping; Wang, Suming; Bhattacharya, Nandita; Vrbanac, Vladimir; Collins, Michael; Signoretti, Sabina; Hu, Yanhui; Boyce, Frederick M.; Gravdal, Karsten; Halvorsen, Ole Johan; Nalwoga, Hawa; Akslen, Lars A.; Harlow, Ed; Watnick, Randolph S. 2014. GRK3 is essential for metastatic cells and promotes prostate tumor progression. Proceedings of the National Academy of Sciences of the United States of America. 1521-1526.
  • Knutsvik, Gøril; Stefansson, Ingunn; Aziz, Sura Mohammed; Arnes, Jarle; Eide, Johan; Collett, Karin; Akslen, Lars A. 2014. Evaluation of Ki67 expression across distinct categories of breast cancer specimens: A Population-based study of matched surgical specimens, core needle biopsies and tissue microarrays. PLOS ONE.
  • Wik, Elisabeth; Trovik, Jone; Kusonmano, Kanthida; Birkeland, Even; Ræder, Maria B; Pashtan, I; Høivik, Erling Andre; Krakstad, Camilla; Werner, Henrica Maria Johanna; Holst, Frederik; Mjøs, Siv; Halle, Mari Kyllesø; Mannelqvist, Monica; Mauland, Karen Klepsland; Øyan, Anne Margrete; Stefansson, Ingunn; Petersen, Kjell; Simon, R; Cherniack, AD; Meyerson, M; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2014. Endometrial Carcinoma Recurrence Score (ECARS) validates to identify aggressive disease and associates with markers of epithelial-mesenchymal transition and PI3K alterations. Gynecologic Oncology. 599-606.
  • Chen, Ying; Klingen, Tor Audun; Wik, Elisabeth; Aas, Hans; Vigeland, Einar; Liestøl, Knut; Garred, Øystein; Mæhlen, Jan; Akslen, Lars A.; Lømo, Jon. 2014. Breast cancer stromal elastosis is associated with mammography screening detection, low Ki67 expression and favourable prognosis in a population-based study. Diagnostic Pathology. 8 sider.
  • Mannelqvist, Monica; Wik, Elisabeth; Stefansson, Ingunn; Akslen, Lars A. 2014. An 18-Gene signature for vascular invasion is associated with aggressive features and reduced survival in breast cancer. PLOS ONE.
  • Hellesøy, Monica; Blois, Anna; Tiron, Crina Elena; Mannelqvist, Monica; Akslen, Lars A.; Lorens, James. 2014. Akt1 activity regulates vessel maturation in a tissue engineering model of angiogenesis. Tissue Engineering. Part A. 2590-2603.
  • Nygård, Yngve; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2014. A positive real-time elastography is an independent marker for detection of high-risk prostate cancers in the primary biopsy setting. BJU International. E90-E97.
  • Hoem, Dag; Straume, Oddbjørn; Immervoll, Heike ; Akslen, Lars A.; Molven, Anders. 2013. Vascular proliferation is associated with survival in pancreatic ductal adenocarcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 1037-1046.
  • Ozhand, Ali; Lee, Eunjung; Wu, Anna H.; Ellingjord-Dale, Merete; Akslen, Lars A.; McKean-Cowdin, Roberta; Ursin, Giske. 2013. Variation in inflammatory cytokine/growth-factor genes and mammographic density in premenopausal women aged 50-55. PLOS ONE. 8 sider.
  • Arnesen, Thomas; Glomnes, Nina; Strømsøy, Siri S.; Knappskog, Stian; Heie, Anette; Akslen, Lars A.; Grytaas, Marianne Aardal; Varhaug, Jan Erik; Gimm, Oliver; Brauckhoff, Michael. 2013. Outcome after surgery for primary hyperaldosteronism may depend on KCNJ5 tumor mutation status: a population-based study from Western Norway. Langenbeck's archives of surgery (Print). 869-874.
  • Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. 2013. Molecular subtypes, histopathological grade and survival in a historic cohort of breast cancer patients. Breast Cancer Research and Treatment. 463-473.
  • Puntervoll, Hanne Eknes; Yang, Xiaohong R.; Vetti, Hildegunn Høberg; Bachmann, Ingeborg M.; Avril, Marie Françoise; Benfodda, Meriem; Catricala, Caterina; Dalle, Stéphane; Duval-Modeste, Anne B.; Ghiorzo, Paola; Grammatico, Paola; Harland, Mark; Hayward, Nicholas K.; Hu, Hui-Han; Jouary, Thomas; Martin-Denavit, Tanguy; Ozola, Aija; Palmer, Jane M.; Pastorino, Lorenza; Pjanova, Dace; Soufir, Nadem; Steine, Solrun; Stratigos, Alexander J.; Thomas, Luc; Tinat, Julie; Tsao, Hensin; Veinalde, Rūta; Tucker, Margaret A.; Bressac-de Paillerets, Brigitte B.D.; Newton-Bishop, Julia A.; Goldstein, Alisa M.; Akslen, Lars A.; Molven, Anders. 2013. Melanoma prone families with CDK4 germline mutation: phenotypic profile and associations with MC1R variants. Journal of Medical Genetics. 264-U82.
  • Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Bofin, Anna M.; Engebråten, Olav; Mælandsmo, Gunhild; Akslen, Lars A.; Gribbestad, Ingrid S. 2013. Low-molecular contrast agent DCE-MRI and DW-MRI in early assessment of bevacizumab treatment in breast cancer xenografts. Journal of Magnetic Resonance Imaging. 1043-1053.
  • Wik, Elisabeth; Ræder, Maria B; Krakstad, Camilla; Trovik, Jone; Birkeland, Even; Høivik, Erling Andre; Mjøs, Siv; Werner, Henrica Maria Johanna; Mannelqvist, Monica; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Lack of estrogen receptor-alpha is associated with epithelial-mesenchymal transition and PI3K alterations in endometrial carcinoma. Clinical Cancer Research. 1094-1105.
  • Ræder, Maria B; Birkeland, Even; Trovik, Jone; Krakstad, Camilla; Shehata, Shyemaa; Schumacher, Steven; Zack, Travis I.; Krohn, Antje; Werner, Henrica Maria Johanna; Moody, Susan E.; Wik, Elisabeth; Stefansson, Ingunn Marie; Holst, Frederik; Øyan, Anne Margrete; Tamayo, Pablo; Mesirov, Jill P.; Kalland, Karl-Henning; Akslen, Lars A.; Simon, Ronald; Beroukhim, Rameen; Salvesen, Helga Birgitte. 2013. Integrated genomic analysis of the 8q24 amplification in endometrial cancers identifies ATAD2 as essential to MYC-dependent cancers. PLOS ONE. 9 sider.
  • Trovik, Jone; Wik, Elisabeth; Werner, Henrica Maria Johanna; Krakstad, Camilla; Helland, Harald; Vandenput, Ingrid; Njølstad, Tormund Salvesen; Stefansson, Ingunn; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. Hormone receptor loss in endometrial carcinoma curettage predicts lymph node metastasis and poor outcome in prospective multicentre trial. European Journal of Cancer. 3431-3441.
  • Garcia-Dios, Diego A; Lambrechts, Diether; Coenegrachts, Lieve; Vandenput, Ingrid; Capoen, An; Webb, Penelope M.; Ferguson, Kaltin; Akslen, Lars A.; Claes, Bart; Vergote, Ignace; Moerman, Philippe; Robays, Johan Van; Marcickiewicz, Janusz; Salvesen, Helga Birgitte; Spurdle, Amanda B; Amant, Frédéric. 2013. High-throughput interrogation of PIK3CA, PTEN, KRAS, FBXW7 and TP53 mutations in primary endometrial carcinoma. Gynecologic Oncology. 327-334.
  • Wik, Elisabeth; Birkeland, Even; Trovik, Jone; Werner, Henrica Maria Johanna; Høivik, Erling Andre; Mjøs, Siv; Krakstad, Camilla; Kusonmano, Kanthida; Mauland, Karen Klepsland; Stefansson, Ingunn Marie; Holst, Frederik; Petersen, Kjell; Øyan, Anne Margrete; Simon, Roland; Kalland, Karl-Henning; Ricketts, William; Akslen, Lars A.; Salvesen, Helga Birgitte. 2013. High phospho-stathmin(Serine38) expression identifies aggressive endometrial cancer and suggests an association with PI3K inhibition. Clinical Cancer Research. 2331-2341.
  • Klingen, Tor Audun; Chen, Ying; Suhrke, Pål; Stefansson, Ingunn Marie; Gundersen, Marian D.; Akslen, Lars A. 2013. Expression of thyroid transcription factor-1 is associated with a basal-like phenotype in breast carcinomas. Diagnostic Pathology.
  • Pedersen, Torbjørn Østvik; Blois, Anna; Xing, Zhe; Xue, Ying; Sun, Yang; Finne-Wistrand, Anna; Akslen, Lars A.; Lorens, James; Leknes, Knut N.; Fristad, Inge; Mustafa, Kamal Babikeir Eln. 2013. Endothelial microvascular networks affect gene-expression profiles and osteogenic potential of tissue-engineered constructs. Stem Cell Research & Therapy. 10 sider.
  • Haldorsen, Ingfrid S.; Grüner, Renate; Husby, Jenny Hild Aase; Magnussen, Inger Johanne; Werner, Henrica Maria Johanna; Salvesen, Øyvind; Bjørge, Line; Stefansson, Ingunn Marie; Akslen, Lars A.; Trovik, Jone; Taxt, Torfinn; Salvesen, Helga Birgitte. 2013. Dynamic contrast-enhanced MRI in endometrial carcinoma identifies patients at increased risk of recurrence. European Radiology. 2916-2925.
  • Catena, Raúl; Bhattacharya, Nandita; El Rayes, Tina; Wang, Suming; Choi, Hyejin; Gao, Dingcheng; Ryu, Seongho; Joshi, Natasha; Bielenberg, Diane; Lee, Sharrell B.; Haukaas, Svein Andreas; Gravdal, Karsten; Halvorsen, Ole Johan; Akslen, Lars A.; Watnick, Randolph S.; Mittal, Vivek. 2013. Bone marrow-derived Gr1(+) cells can generate a metastasis-resistant microenvironment via induced secretion of thrombospondin-1. Cancer Discovery. 578-589.
  • Veinalde, Rūta; Ozola, Aija; Azarjana, Kristine; Molven, Anders; Akslen, Lars A.; Donina, Simona; Proboka, Guna; Cema, Ingrida; Baginskis, Ainars; Pjanova, Dace. 2013. Analysis of Latvian familial melanoma patients shows novel variants in the noncoding regions of CDKN2A and that the CDK4 mutation R24H is a founder mutation. Melanoma research. 221-226.
  • Werner, Henrica Maria Johanna; Berg, Anna; Wik, Elisabeth; Birkeland, Even; Krakstad, Camilla; Kusonmano, Kanthida; Petersen, Kjell; Kalland, Karl-Henning; Øyan, Anne Margrete; Akslen, Lars A.; Trovik, Jone; Salvesen, Helga Birgitte. 2013. ARID1A loss is prevalent in endometrial hyperplasia with atypia and low-grade endometrioid carcinomas. Modern Pathology. 428-434.
  • Iles, Mark M.; Law, Matthew H.; Stacey, Simon N.; Han, Jiali; Fang, Shenying; Pfeiffer, Ruth; Harland, Mark; MacGregor, Stuart; Taylor, John C.; Aben, Katja K.; Akslen, Lars A.; Avril, Marie Françoise; Azizi, Esther; Bakker, Bert; Benediktsdottir, Kristun R.; Bergman, Wilma; Scarra, Giovanna Bianchi; Brown, Kevin M.; Calista, Donato; Chaudru, Valerie; Fargnoli, Marie Concetta; Cust, Anne E.; Demenais, Florence; de Waal, Anne C.; Debniak, Tadeusz; Elder, David E.; Friedman, Eitan; Galan, Pilar; Ghiorzo, Paola; Gillanders, Elizabeth M.; Goldstein, Alisa M.; Gruis, Nelleke A.; Hansson, Johan; Helsing, Per; Hočevar, Marko; Höiom, Veronica; Hopper, John L.; Ingvar, Christian; Janssen, Marjolein; Jenkins, Mark A.; Kanetsky, Peter A.; Kiemeney, Lambertus A.; Lang, Julie L.; Lathrop, G. Mark; Leachman, Sancy; Lee, Jeffrey E.; Lubiński, Jan; Mackie, Rona M.; Mann, Graham J.; Martin, Nicholas G.; Mayordomo, Jose Ignacio; Molven, Anders; Mulder, Suzanne; Nagore, Eduardo; Novakovic, Srdjan; Okamoto, Ichiro; Olafsson, Jon H.; Olsson, Håkan; Pehamberger, Hubert; Peris, Ketty; Grasa, Maria Pilar; Planelles, Dolores; Puig, Susana; Puig-Butille, Joan Anton; Randerson-Moor, Juliette; Requena, Celia; Rivoltini, Licia; Rodolfo, Monica; Santinami, Mario; Sigurgeirsson, Bardur; Snowden, Helen; Song, Fengju; Sulem, Patrick; Thorisdottir, Kristin; Tuominen, Rainer; Van Belle, Patricia; van der Stoep, Nienke; van Rossum, Michelle M.; Wei, Qingyi; Wendt, Judith; Zelenika, Diane; Zhang, Mingfeng; Landi, Maria Teresa; Thorleifsson, Gudmar; Bishop, D. Timothy; Amos, Christopher I.; Hayward, Nicholas K.; Stefansson, Kari; Bishop, Julia A. Newton; Barrett, Jennifer H. 2013. A variant in FTO shows association with melanoma risk not due to BMI. Nature Genetics. 428-432.
  • Arnes, Jarle; Stefansson, Ingunn Marie; Straume, Oddbjørn; Baak, Jan P.A.; Lønning, Per Eystein; Foulkes, William D.; Akslen, Lars A. 2012. Vascular proliferation is a prognostic factor in breast cancer. Breast Cancer Research and Treatment. 501-510.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Tumor necrosis is a prognostic factor in thick cutaneous melanoma. American Journal of Surgical Pathology. 1477-1482.
  • Straume, Oddbjørn; Shimamura, Takeshi; Lampa, Michael J.G.; Carretero, Julian; Øyan, Anne Margrete; Jia, Di; Borgman, Christa L.; Soucheray, Margaret; Downing, Sean R.; Short, Sarah M.; Kang, Soo-Young; Wang, Suoming; Chen, Liang; Collett, Karin; Bachmann, Ingeborg M.; Wong, Kwok-Kin; Shapiro, Geoffrey I.; Kalland, Karl-Henning; Folkman, Judah; Watnick, Randolph S.; Akslen, Lars A.; Naumov, George N. 2012. Suppression of heat shock protein 27 induces long-term dormancy in human breast cancer. Proceedings of the National Academy of Sciences of the United States of America. 8699-8704.
  • Ladstein, Rita Grude; Bachmann, Ingeborg M.; Straume, Oddbjørn; Akslen, Lars A. 2012. Prognostic Importance of the Mitotic Marker Phosphohistone H3 in Cutaneous Nodular Melanoma. Journal of Investigative Dermatology. 1247-1252.
  • Ellingjord-Dale, Merete; Lee, Eunjung; Couto, Elisabeth; Ozhand, Ali; Qureshi, Samera Azeem; Hofvind, Solveig; Van Den Berg, David J; Akslen, Lars A.; Grotmol, Tom; Ursin, Giske. 2012. Polymorphisms in hormone metabolism and growth factor genes and mammographic density in Norwegian postmenopausal hormone therapy users and non-users. Breast Cancer Research.
  • Brauckhoff, Michael; Varhaug, Jan Erik; Hauptmann, Steffen; Akslen, Lars A.; Thanh, P. Nguyen; Viste, Asgaut; Heie, Anette; Dralle, Henning. 2012. Peritoneal carcinosis in apparently benign cortisol producing adrenal adenoma >= 5 cm in diameter: the need of regular postoperative surveillance. Experimental and clinical endocrinology & diabetes. 472-476.
  • Krüger, Kristi; Stefansson, Ingunn Marie; Collett, Karin; Arnes, Jarle; Aas, Turid; Akslen, Lars A. 2012. Microvessel proliferation by co-expression of endothelial nestin and Ki-67 is associated with a basal-like phenotype and aggressive features in breast cancer. Breast. 1-7.
  • Helsing, Per; Nymoen, Dag Andre; Rootwelt, Helge; Vårdal, Mari H; Akslen, Lars A.; Molven, Anders; Andresen, Per Arne. 2012. MC1R, ASIP, TYR, and TYRP1 gene variants in a population-based series of multiple primary melanomas. Genes, Chromosomes and Cancer. 654-661.
  • Krakstad, Camilla; Trovik, Jone; Wik, Elisabeth; Engelsen, Ingeborg Bøe; Werner, Henrica Maria Johanna; Birkeland, Even; Ræder, Maria B; Øyan, Anne Margrete; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga Birgitte. 2012. Loss of GPER identifies new targets for therapy among a subgroup of ER alpha-positive endometrial cancer patients with poor outcome. British Journal of Cancer. 1682-1688.
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Wik, Elisabeth; Kusonmano, Kanthida; Ræder, Maria B; Øyan, Anne Margrete; Kalland, Karl-Henning; Moses, Marsha A.; Salvesen, Helga Birgitte; Akslen, Lars A. 2012. Lipocalin 2 expression is associated with aggressive features of endometrial cancer. BMC Cancer. 7 sider.
  • Birkeland, Even; Wik, Elisabeth; Mjøs, Siv; Høivik, Erling Andre; Trovik, Jone; Werner, Henrica Maria Johanna; Kusonmano, Kanthida; Petersen, Kjell; Ræder, Maria B; Holst, Frederik; Øyan, Anne Margrete; Kalland, Karl-Henning; Akslen, Lars A.; Simon, R; Krakstad, Camilla; Salvesen, Helga Birgitte. 2012. KRAS gene amplification and overexpression but not mutation associates with aggressive and metastatic endometrial cancer. British Journal of Cancer. 1997-2004.
  • Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita Maria; Bathen, Tone Frost; Nalwoga, Hawa; Krüger, Kristi; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebråten, Olav; Gribbestad, Ingrid S. 2012. In vivo MRI and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts. Journal of Magnetic Resonance Imaging. 1098-1107.
  • Moen, Ingrid; Jevne, Alison Charlotte; Wang, Jian; Kalland, Karl-Henning; Chekenya, Martha; Akslen, Lars A.; Sleire, Linda; Enger, Per Øyvind; Reed, Rolf K.; Øyan, Anne Margrete; Stuhr, Linda Elin Birkhaug. 2012. Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 10 sider.
  • Lindholm, Evita Maria; Kristian, Alexandr; Nalwoga, Hawa; Kruger, Kristi; Nygård, Ståle; Akslen, Lars A.; Mælandsmo, Gunhild; Engebråten, Olav. 2012. Effect of antiangiogenic therapy on tumor growth, vasculature and kinase activity in basal- and luminal-like breast cancer xenografts. Molecular Oncology. 418-427.
  • Nygård, Yngve; Haukaas, Svein Andreas; Waage, Jo Erling Riise; Halvorsen, Ole Johan; Gravdal, Karsten; Frugård, Jannicke; Akslen, Lars A.; Beisland, Christian. 2012. Combination of real-time elastography and urine prostate cancer gene 3 (PCA3) detects more than 97 % of significant prostate cancers. Scandinavian Journal of Urology and Nephrology. 211-216.
  • Schuster, Cornelia; Eikesdal, Hans Petter; Puntervoll, Hanne Eknes; Geisler, Jürgen; Geisler, Stephanie; Heinrich, Daniel; Molven, Anders; Lønning, Per Eystein; Akslen, Lars A.; Straume, Oddbjørn. 2012. Clinical efficacy and safety of bevacizumab monotherapy in patients with metastatic melanoma: predictive importance of induced early hypertension. PLOS ONE. 8 sider.
  • Nalwoga, Hawa; Arnes, Jarle; Stefansson, Ingunn Marie; Wabinga, Henry; Foulkes, William D.; Akslen, Lars A. 2011. Vascular proliferation is increased in basal-like breast cancer. Breast Cancer Research and Treatment. 1063-1071.
  • Trovik, Jone; Wik, Elisabeth; Stefansson, Ingunn Marie; Marcickiewicz, Janusz; Tingulstad, Solveig; Staff, Anne Cathrine; Njølstad, Tormund Salvesen; Vandenput, Ingrid; Amant, Frédéric; Akslen, Lars A.; Salvesen, Helga Birgitte; Ellstrøm Engh, Marie; Oddenes, Klaus; Rokne, Jan Anders; Tjugum, Jostein; Lode, Margaret Sævik. 2011. Stathmin Overexpression Identifies High-Risk Patients and Lymph Node Metastasis in Endometrial Cancer. Clinical Cancer Research. 3368-3377.
  • Ke, Xisong; Li, Wencheng; Hovland, Randi; Qu, Yi; Liu, Run-hui; McCormack, Emmet Martin; Thorsen, Frits Alan; Olsen, Jan Roger; Molven, Anders; Kogan-Sakin, Ira; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2011. Reprogramming of cell junction modules during stepwise epithelial to mesenchymal transition and accumulation of malignant features in vitro in a prostate cell model. Experimental Cell Research. 234-247.
  • Myklebust, Line Merethe; Akslen, Lars A.; Varhaug, Jan Erik; Lillehaug, Johan R. 2011. Receptor for Activated Protein C Kinase 1 (RACK1) Is Overexpressed in Papillary Thyroid Carcinoma. Thyroid. 1217-1225.
  • Mauland, Karen Klepsland; Trovik, Jone; Wik, Elisabeth; Ræder, Maria B; Njølstad, Tormund Salvesen; Stefansson, Ingunn Marie; Øyan, Anne Margrete; Kalland, Karl-Henning; Bjørge, Tone; Akslen, Lars A.; Salvesen, Helga Birgitte. 2011. High BMI is significantly associated with positive progesterone receptor status and clinico-pathological markers for non-aggressive disease in endometrial cancer. British Journal of Cancer. 921-926.
  • Akslen, Lars A.; Straume, Oddbjørn; Geisler, Stephanie; Sørlie, Therese; Chi, Jen-Tan Ashley; Aas, Turid; Børresen-Dale, Anne-Lise ; Lønning, Per Eystein. 2011. Glomeruloid microvascular proliferation is associated with lack of response to chemotherapy in breast cancer. British Journal of Cancer. 9-12.
  • Barrett, Jennifer H.; Iles, MM; Harland, M; Taylor, JC; Aitken, JF; Andresen, Per Arne; Akslen, Lars A.; Armstrong, BK; Avril, MF; Azizi, E; Bakker, B; Bergman, W; Bianchi-Scarra, G; Bressac-de Paillerets, B; Calista, D; Cannon-Albright, LA; Corda, E; Cust, AE; Debniak, T; Duffy, D; Dunning, AM; Easton, DF; Friedman, E; Galan, P; Ghiorzo, P; Giles, GG; Hansson, J; Hocevar, M; Hoiom, V; Hopper, JL; Ingvar, C; Janssen, B; Jenkins, MA; Jonsson, G; Kefford, RF; Landi, G; Landi, MT; Lang, J; Lubinski, J; Mackie, R; Malvehy, J; Martin, NG; Molven, Anders; Montgomery, GW; van Nieuwpoort, FA; Novakovic, S; Olsson, H; Pastorino, L; Puig, S; Puig-Butille, JA; Randerson-Moor, J; Snowden, H; Tuominen, R; VanBelle, P; van der Stoep, N; Whiteman, DC; Zelenika, D; Han, JL; Fang, SY; Lee, JE; Wei, QY; Lathrop, GM; Gillanders, EM; Brown, KM; Goldstein, AM; Kanetsky, PA; Mann, GJ; MacGregor, S; Elder, DE; Amos, CI; Hayward, NK; Gruis, NA; Demenais, F; Bishop, JAN; Bishop, D. Timothy. 2011. Genome-wide association study identifies three new melanoma susceptibility loci. Nature Genetics. 1108-U98.
  • Mannelqvist, Monica; Stefansson, Ingunn Marie; Bredholt, Geir; Bø, Trond Hellem; Øyan, Anne Margrete; Jonassen, Inge; Kalland, Karl-Henning; Salvesen, Helga Birgitte; Akslen, Lars A. 2011. Gene Expression Patterns Related to Vascular Invasion and Aggressive Features in Endometrial Cancer. American Journal of Pathology. 861-871.
  • Vandenput, Ingrid; Trovik, Jone; Leunen, Karin; Wik, Elisabeth; Stefansson, Ingunn Marie; Akslen, Lars A.; Moerman, Philippe; Vergote, Ignace; Salvesen, Helga Birgitte; Amant, Frédéric. 2011. Evolution in endometrial cancer evidence from an immunohistochemical study. International Journal of Gynecological Cancer. 316-322.
  • Hegen, Anja; Blois, Anna; Tiron, Crina Elena; Hellesøy, Monica; Micklem, David Robert; Nör, Jacques E; Akslen, Lars A.; Lorens, James. 2011. Efficient in vivo vascularization of tissue-engineering scaffolds. Journal of Tissue Engineering and Regenerative Medicine. E52-E62.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, Henry; Akslen, Lars A. 2010. Expression of aldehyde dehydrogenase a (ALDH1) is associated with basal-like markers and features of aggressive tumors in African breast cancer. British Journal of Cancer. 369-375.
  • Gjerdrum, Christine; Tiron, Crina Elena; Høiby, Torill; Stefansson, Ingunn Marie; Haugen, Hallvard; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2010. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Proceedings of the National Academy of Sciences of the United States of America. 1124-1129.
  • Klingen, Tor Audun; Klaasen, Herman; Chen, Ying; Akslen, Lars A. 2009. Secondary breast cancer: a 5-year population-based study with review of the literature. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 762-767.
  • Bruland, Ove; Fluge, Øystein; Akslen, Lars A.; Eiken, Hans Geir; Lillehaug, Johan R.; Varhaug, Jan Erik; Knappskog, Per Morten. 2009. Inverse correlation between PDGFC expression and lymphocyte infiltration in human papillary thyroid carcinomas. BMC Cancer. 425.
  • Fluge, Øystein; Gravdal, K; Carlsen, Erik; Vonen, Barthold; Kjellevold, K; Refsum, S; Lilleng, R; Eide, Tor J.; Halvorsen, TB; Tveit, Kjell Magne; Otte, AP; Akslen, LA; Dahl, O. 2009. Expression of EZH2 and Ki-67 in colorectal cancer and associations with treatment response and prognosis. British Journal of Cancer. 1282-1289.
  • Mæhle, Bjørn Ove; Collett, Karin; Tretli, Steinar; Akslen, Lars A.; Grotmol, Tom. 2009. Estrogen receptor β– an independent prognostic marker in estrogen receptor α and progesterone receptor-positive breast cancer? Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 644-650.
  • Wik, Elisabeth; Trovik, Jone; Iversen, Ole-Erik; Engelsen, Ingeborg Bøe; Stefansson, Ingunn Marie; Vestrheim, LC; Haugland, Hans K.; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Deoxyribonucleic acid ploidy in endometrial carcinoma: a reproducible and valid prognostic marker in a routine diagnostic setting. American Journal of Obstetrics and Gynecology. 603-607.
  • Naumov, George N.; Nilsson, Monique B.; Cascone, Tina; Briggs, Alexandra; Straume, Oddbjørn; Akslen, Lars A.; Lifshits, Eugene; Byers, Lauren Averett; Xu, Li; Wu, Hua-kang; Jänne, Pasi; Kobayashi, Susumu; Halmos, Balazs; Tenen, Daniel; Tang, Xi M.; Engelman, Jeffrey; Yeap, Beow; Folkman, Judah; Johnson, Bruce E.; Heymach, John V. 2009. Combined vascular endothelial growth factor receptor and epidermal growth factor receptor (EGFR) blockade inhibits tumor growth in xenograft models of EGFR inhibitor resistance. Clinical Cancer Research. 3484-3494.
  • Engelsen, Ingeborg Bøe; Stefansson, IM; Akslen, Lars A.; Salvesen, Helga Birgitte. 2008. GATA3 expression in estrogen receptor alpha-negative endometrial carcinomas identifies aggressive tumors with high proliferation and poor patient survival. American Journal of Obstetrics and Gynecology. e 1-7.
  • Tischkowitz, Marc; Brunet, Jean-Sébastien; Bégin, Louis R.; Huntsman, David G.; Cheang, Maggie C.U. ; Akslen, Lars A.; Nielsen, Torsten O.; Foulkes, William D. 2007. Use of immunohistochemical markers can refine prognosis in triple negative breast cancer. BMC Cancer. 11 sider.
  • Petersen, Kjell; Øyan, Anne Margrete; Rostad, Kari; Olsen, Sue; Bø, Trond Hellem; Salvesen, Helga; Gjertsen, Bjørn Tore; Bruserud, Øystein; Halvorsen, Ole Johan; Akslen, Lars A.; Steen, Vidar Martin; Jonassen, Inge; Kalland, Karl-Henning. 2007. Comparison of nucleic acid targets prepared from total RNA or poly(A) RNA for DNA oligonucleotide microarray hybridization. Analytical Biochemistry. 46-58.
  • Stefansson, Ingunn Marie; Salvesen, Helga; Akslen, Lars A. 2006. Loss of p63 and cytokeratin 5/6 expression is associated with more aggressive tumors in endometrial carcinoma patients. International Journal of Cancer. 1227-1233.
  • Haukaas, Svein Andreas; Halvorsen, Ole Johan; Dæhlin, Lars; Høstmark, Jens; Akslen, Lars A. 2006. Is preoperative serum prostate-specific antigen level significantly related to clinical recurrence after radical 14 retropubic prostatectomy for localized prostate cancer? BJU International. 51-55.
  • Sørlie, Therese; Perou, Charles M.; Fan, Cheng; Geisler, Stephanie; Aas, Turid; Nobel, Andrew; Anker, Gun; Akslen, Lars A.; Botstein, David; Børresen-Dale, Anne-Lise; Lønning, Per Eystein. 2006. Gene expression profiles do not consistently predict the clinical treatment response in locally advanced breast cancer. Molecular Cancer Therapeutics. 2914-2918.
  • Fluge, Øystein; Bruland, Ove; Akslen, Lars A.; Lillehaug, Johan; Varhaug, Jan Erik. 2006. Gene expression in poorly differentiated papillary thyroid carcinomas. Thyroid. 161-175.
  • Collett, Karin; Eide, Geir Egil; Arnes, Jarle; Stefansson, Ingunn Marie; Eide, Johan; Braaten, Audun; Aas, Turid; Otte, Ariel P.; Akslen, Lars A. 2006. Expression of enhancer of zeste homologue 2 is significantly associated with increased tumor cell proliferation and is a marker of aggressive breast cancer. Clinical Cancer Research. 1168-1174.
  • Bachmann, Ingeborg Margrethe; Halvorsen, Ole Johan; Collett, Karin; Stefansson, Ingunn Marie; Straume, Oddbjørn; Haukaas, Svein Andreas; Salvesen, Helga; Otte, Arie P.; Akslen, Lars A. 2006. EZH2 expression is associated with high proliferation rate and aggressive tumor subgroups in cutaneous melanoma and cancers of the endometrium, prostate, and breast. Journal of Clinical Oncology. 268-273.
  • Engeland, Anders; Tretli, Steinar; Akslen, Lars Andreas; Bjørge, Tone. 2006. Body size and thyroid cancer in two million Norwegian men and women. British Journal of Cancer. 366-370.
  • Naumov, George N.; Bender, Elise; Zurakowski, David; Kang, Soo-Young; Sampson, David; Flynn, Evelyn; Watnick, Randolph S.; Straume, Oddbjørn; Akslen, Lars A.; Folkman, Judah; Almog, Nava. 2006. A model of human tumor dormancy: An angiogenic switch from the nonangiogenic phenotype. Journal of the National Cancer Institute. 316-325.
  • Straume, Oddbjørn; Akslen, Lars A. 2005. Strong expression of ID1 protein is associated with decreased survival, increased expression of ephrin-A1/EPHA2, and reduced thrombospondin-1 in malignant melanoma. British Journal of Cancer. 933-938.
  • Salvesen, Helga; Kumar, Rajiv; Stefansson, Ingunn Marie; Angelini, Sabrina; MacDonald, Nicola; Smeds, Johanna; Jacobs, Ian J.; Hemminki, Kari; Das, Soma; Akslen, Lars A. 2005. Low frequency of BRAF and CDKN2A mutations in endometrial cancer. International Journal of Cancer. 930-934.
  • Bachmann, Ingeborg; Straume, Oddbjørn; Puntervoll, Hanne Eknes; Kalvenes, May Britt; Akslen, Lars A. 2005. Importance of P-cadherin, beta-catenin, and Wnt5a/frizzled for progression of melanocytic tumors and prognosis in cutaneous melanoma. Clinical Cancer Research. 8606-8614.
  • Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Skaane, P; Urdal, Petter; Berghagen, Hege; Jensen, Maianne; Kristiansen, Lena; Moen, Cecilie; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Sauer, Toril; Akslen, Lars A; Schlichting, Ellen; Børresen-Dale, Anne-Lise ; Lönneborg, Anders. 2005. Early detection of brest cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. R634-R644.
  • Sharma, Praveen; Sahni, Narinder S; Tibshirani, Robert; Skaane, Per; Urdal, Petter; Berghagen, Hege; Jensen, Marianne; Moen, Cecilie; Kristiansen, Lena; Sharma, Pradeep; Zaka, Alia; Arnes, Jarle; Sauer, Torill; Akslen, Lars A.; Schlichting, Ellen; Børresen-Dale, Anne-Lise; Lönneborg, Anders. 2005. Early detection of breast cancer based on gene-expression patterns in peripheral blood cells. Breast Cancer Research. 634-644.
  • Akslen, Lars A.; Angelini, Sabrina; Straume, Oddbjørn; Molven, Anders; Bachmann, Ingeborg; Hemminki, Kari; Kumar, Rajiv. 2005. BRAF and NRAS mutations are frequent in nodular melanoma but are not associated with tumor cell proliferation or patient survival. Journal of Investigative Dermatology. 312-317.
  • Molven, Anders; Grimstvedt, Magne B.; Steine, Solrun; Harland, Mark; Avril, Marie-Françoise; Hayward, Nicholas K.; Akslen, Lars A. 2005. A large Norwegian family with inherited malignant melanoma, multiple atypical nevi, and CDK4 mutation. Genes, Chromosomes and Cancer. 10-18.
  • Geisler, Stephanie; Børresen-Dale, Anne-Lise; Johnsen, Hilde; Aas, Turid; Geisler, Jürgen; Akslen, Lars A.; Anker, Gun; Lønning, Per Eystein. 2003. TP53 gene mutations predict the response to neoadjuvant treatment with 5-fluorouracil and mitomycin in locally advanced breast cancer. Clinical Cancer Research. 5582-5588.
  • Salvesen, Helga B.; Gulluoglu, Mine G; Stefansson, Ingunn Marie; Akslen, Lars A. 2003. Significance of CD 105 expression for tumour angiogenesis and prognosis in endometrial carcinomas. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 1011-1018.
  • Aas, Turid; Geisler, Stephanie; Eide, Geir Egil; Haugen, Dagny R. Faksvåg; Varhaug, Jan Erik; Bassøe, Anne Margrethe; Thorsen, Thor; Berntsen, Hildegunn; Børresen-Dale, AL; Akslen, Lars A.; Lønning, Per Eystein. 2003. Predictive value of tumour cell proliferation in locally advanced breast cancer treated with neoadjuvant chemotherapy. European Journal of Cancer. 438-446.
  • Alexander-Sefre, F; Salvesen, Helga B.; Abeler, N; Singh, N; Akslen, Lars A.; MacDonald, N; Wilbanks, G; Jacobs, IJ. 2003. Molecular assessment of depth of myometrial invasion in stage I endometrial cancer: a model based on K-ras mutation analysis. Gynecologic Oncology. 218-25.
  • Halford, SE; Sawyer, EJ; Lambros, MB; Gorman, P; MacDonald, ND; Talbot, IC; Foulkes, WD; Gillett, CE; Barnes, DM; Akslen, Lars A.; Lee, K; Jacobs, IJ; anby, AM; Ganesan, TS; Salvesen, Helga B.; Bodner, WF; Tomlinson, IP; Roylance, RR. 2003. MSI-low, a real phenomenon which varies in frequency among cancer types. Journal of Pathology. 389-94.
  • Foulkes, WD; Stefansson, Ingunn Marie; Chappuis, PO; Begin, LR; Goffin, JR; Wong, N; Trudel, M; Akslen, Lars A. 2003. Germline BRCA1 mutations and a basal epithelial phenotype in breast cancer. Journal of the National Cancer Institute. 1482-85.
  • Halvorsen, Ole J.; Haukaas, Sven; Akslen, Lars A. 2003. Combined loss of PTEN and p27 expression is associated with tumor cell proliferation by Ki-67 and increased risk of recurrent disease in localized prostate cancer. Clinical Cancer Research. 1474-1479.
  • Gjengstø, Peder; Halvorsen, Ole J.; Akslen, Lars A.; Frugård, Jannicke; Høisæter, Per Åge. 2003. Benign growth of different prostate zones in aging men with slightly elevated PSA in whom prostate cancer has been excluded: a prospective study of 510 patients. Urology. 447-450.
  • Vuhahula, E; Straume, Oddbjørn; Akslen, Lars A. 2000. Frequent loss of p16 protein expression and high proliferative activity (Ki-67) in malignant melanoma from black Africans. Anticancer Research. 4857-62.
  • Das, S; MacDonald, N; Ryan, A; Jacobs, IJ; Lynch, ED; Akslen, Lars A.; Salvesen, Helga. 1999. The PTEN gene is methylated in endometrial carcinoma and associated with advanced disease and microsattelite instability. (Abs. no. 207). American Journal of Human Genetics. S. 209.
  • Lønning, Per Eystein; Johnsen, H; Geisler, Stephanie; Aas, T; Smith-Sørensen, B; Akslen, Lars A.; Børresen-Dale, AL. 1999. TP53 as a predictor of response to chemotherpy in breast cancer. RSO Scientific Updates. 73-88.
  • Salvesen, Helga; Akslen, Lars A. 1999. Strong prognostic influence of reduced p16 protein expression in endometrial carcinomas. A large population based study. (Abstract no. 0-079). Virchows Archiv. 185.
  • Salvesen, Helga; Akslen, Lars A. 1999. Significance of tumor associated macrophages. VEGF and TSP-1 expression for tumor angiogenesis and prognosis in endometrial carcinomas. International Journal of Cancer. 539-543.
  • Salvesen, Helga; Akslen, Lars A. 1999. Significance of tumor associated macrophages, VEGF and TSP-1 for angiogenesis and prognosis of endometrial carcinoma. International Journal of Cancer. 538-43.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1999. Prognostic value of tumor angiogenesis, Ki67, p53 and p21 protein expression - a population based endometrial carcinoma study. Journal of Clinical Oncology. 595-99.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1999. Prognostic significance of tumor angiogenesis, Ki-67, p53 and p21 expression - a population-based endometrial carcinoma study. Journal of Clinical Oncology. 1382-1390.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1999. Prognostic significance of angiogenesis, Ki-67, p53 and p21 expression - a population-based endometrial carcinoma study. International Journal of Oncology. 395-399.
  • Straume, Oddbjørn; Akslen, Lars A. 1999. Loss of nuclear expression of p16 protein correlates with increased tumor cell proliferation and poor patient outcome in patients with vertical growth phase melanoma. (Abstract no. P-487). Virchows Archiv. 314.
  • Geisler, Stephanie; Lønning, Per Eystein; Aas, T; Johnsen, H; Fluge, Ø; Haugen, Dagny R. Faksvåg; Lillehaug, Johan; Akslen, Lars A.; Børresen-Dale, AL. 1999. Influence of TP53 gene alterations and Her-2 expression on the respons to treatment with doxorubicin in locally advanced breast cancer. (Abs. no. 227). Breast Cancer Research and Treatment.
  • Hove, Leif M; Akslen, Lars A. 1999. Clinicopathological characteristics of melanomas of the hand. Journal of Hand Surgery - British and European Volume. 460-64.
  • Hove, Leif M; Akslen, Lars A. 1999. Clinicopathological characteristics of melanomas of the hand. Journal of Hand Surgery - British and European Volume. 460-64.
  • Straume, Oddbjørn; Salvesen, Helga; Akslen, Lars A. 1999. Angiogenesis is prognostically important in vertical growth phase melanomas. International Journal of Oncology. 595-599.
  • Heuch, Jane M.; Heuch, Ivar; Akslen, Lars A.; Kvåle, Gunnar. 1998. Risk of primary childhood brain tumors related to birth characteristics: a Norwegian prospective study. International Journal of Cancer. 498-503.
  • Heuch, Jane M.; Heuch, Ivar; Akslen, Lars A.; Kvåle, Gunnar. 1998. Risk of primary childhood brain tumors related to birth characteristics: a Norwegian prospective study. International Journal of Cancer. 498-503.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1998. Prognostic impact of morphometric nuclear grade in endometrial carcinoma. Cancer. 956-964.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1998. Independent prognostic importance of microvessel density in endometrial carcinoma. British Journal of Cancer. 1140-1144.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1998. Independent prognostic importance of microvessel density in endometrial carcinoma. British Journal of Cancer. 1140-1144.
  • Haugen, Dagny R. Faksvåg; Varhaug, Jan Erik; Akslen, Lars A.; Lillehaug, Johan. 1998. Diagnostisk molekylærbiologi ved solide svulster - thyreoidea. Tidsskrift for Den norske legeforening. 2199-2203.
  • Salvesen, Helga; Akslen, Lars A.; Iversen, Torbjørn; Iversen, Ole-Erik. 1997. Recurrence of endometrial carcinoma and the value of routine follow up. British Journal of Obstetrics and Gynaecology. 1302-1307.
  • Salvesen, Helga; Akslen, Lars A. 1997. Recurrence of endometrial carcinoma and the value of routine follow up. British Journal of Obstetrics and Gynaecology. 1302-1307.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1997. Prognostisk betydning av tumorbiologiske markører ved kreft i livmorslimhinnen. Kreftnytt. 4-7.
  • Paulsen, Trond H; Aas, Turid; Børresen, Anne-Lise; Varhaug, Jan Erik; Lønning, Per Eystein; Akslen, Lars A. 1997. Angiogenesis does not predict clinical response to doxorubicin monotherapy in patients with locally advanced breast cancer. International Journal of Cancer. 138-140.
  • Paulsen, Trond H; Aas, Turid; Børresen, A-L; Varhaug, Jan Erik; Lønning, Per Eystein; Akslen, Lars A. 1997. Angiogenesis does not predict clinical response to doxorubicin monotherapy in patients with locally advanced breast cancer. International Journal of Cancer. 138-140.
  • Ellis, PA; Lønning, Per Eystein; Børresen-Dale, Anne-Lise; Aas, T; Geisler, Stephanie; Akslen, Lars A.; Salter, I; Smith, IE; Dowsett, M. 1997. Absence of p21 expression is associated with abnormal p53 in human breast carcinomas. British Journal of Cancer. 480-485.
  • Ellis, PA; Lønning, Per Eystein; Aas, Turid; Børresen, AL; Geisler, Stephanie; Akslen, Lars A.; Salter, J; Smith, IE; Dowsett, M. 1997. Absence of p21 expression is associated with abnormal p53 in human breast carcinomas. British Journal of Cancer. 480-485.
  • Salvesen, Helga; Njølstad, Pål Rasmus; Akslen, Lars A.; Abreksten, Grethe; Viste, Asgaut; Søreide, Odd; Varhaug, Jan Erik. 1991. Thyroid carcinoma: Results from surgical treatment in 211consecutive patients. European Journal of Surgery. 521-526.
  • Akslen, Lars A.; Haldorsen, T.; Thoresen, Steinar Østerbø; Glattre, E. 1991. Survival and cause of death in thyroid cancer: A population-based study of 2479 cases from Norway. Cancer Research. 1234-1241.
  • Dæhlin, L.; Akslen, Lars A.; Haukaas, Svein Andreas. 1991. Squamous cell carcinoma of the urinary bladder. Scandinavian Journal of Urology and Nephrology. 275-276.
  • Glattre, E.; Høstmark, A.; Thoresen, Steinar Østerbø; Smith, A. J.; Akslen, Lars A. 1990. Provocation of thyroid neoplasms in female Wistar rats fed n-3 or n-6 fatty acids in the feed. Thyroidology. 1-3.
  • Akslen, Lars A.; Andersen, Knut-Jan; Bjerkvig, Rolf. 1988. Characteristics of Human and Rat Glioma Cells Grown in a Defined Medium. Anticancer Research. 797-804.
Vitenskapelig foredrag
  • Valla, Marit; Vatten, Lars Johan; Engstrøm, Monica J; Haugen, Olav Anton; Akslen, Lars A.; Bjørngaard, Johan Håkon; Hagen, Anne Irene; Ytterhus, Borgny; Bofin, Anna M.; Opdahl, Signe. 2016. Molecular subtypes of breast cancer: long-term incidence trends and prognostic differences.
  • Valla, Marit; Engstrøm, Monica J; Ytterhus, Borgny; Hansen, Åse Kristin Skain; Akslen, Lars A.; Vatten, Lars Johan; Opdahl, Signe; Bofin, Anna M. 2016. FGD5 amplification in breast cancer patients is associated with tumour proliferation and a poorer prognosis.
  • Engstrøm, Monica J; Opdahl, Signe; Hansen, Åse Kristin Skain; Romundstad, Pål Richard; Vatten, Lars Johan; Akslen, Lars A.; Hagen, Anne Irene; Haugen, Olav Anton; Bofin, Anna M. 2013. Molekylære subtyper og overlevelse ved brystkreft.
  • Engstrøm, Monica J; Opdahl, Signe; Hagen, Anne Irene; Romundstad, Pål Richard; Akslen, Lars A.; Haugen, Olav A.; Vatten, Lars Johan; Bofin, Anna M. 2013. Molekylære subtyper og overlevelse ved brystkreft.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Haugland, Hans Kristian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2012. Multimodal imaging for suspected recurrent differentiated thyroid cancer (DTC): FDG-PET-CT, I-131-SPECT-CT, ultrasound (US) and US-guided fine needle biopsy (FNB).
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2011. Multimodal imaging for diagnosis and treatment of recurrent differentiated thyroid cancer (DTC)FDG-PET-CT, contrast-enhanced CT (CE-CT), I-131-SPECT-CT, ultrasound (US) and US-guided fine needle biopsy (FNB).
  • Huuse, Else Marie; Moestue, Siver Andreas; Bathen, Tone Frost; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebråten, Olav; Gribbestad, Ingrid S. 2011. In vivo Dynamic Contrast Enhanced MRI & Histopathological Assessment of Tumor Angiogenesis in Luminal-like and Basal-like Breast Cancer Xenografts.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2011. FDG-PET-CT, I-131-SPECT-CT, ultrasound (US) and US-guided fine needle biopsy (FNB) for recurrent differentiated thyroid cancer (DTC).
  • Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Akslen, Lars A.; Engebråten, Olav; Mælandsmo, Gunhild; Gribbestad, Ingrid S. 2011. Early vascular response to bevacizumab treatment measured by DCE-MRI in breast cancer xenografts.
  • Moestue, Siver Andreas; Huuse, Else Marie; Lindholm, Evita Maria; Engebråten, Olav; Akslen, Lars A.; Mælandsmo, Gunhild; Gribbestad, Ingrid S. 2011. DCE-MRI for early therapy monitoring of anti-angiogenic therapy.
  • Nygård, Yngve; Waage, Jo Erling Riise; Halvorsen, Ole Johan; Gravdal, Karsten; Akslen, Lars A.; Frugård, Jannicke; Haukaas, Svein Andreas; Beisland, Christian. 2010. Real time elastografi ved cancer prostatae.
  • Nygård, Yngve; Halvorsen, Ole Johan; Gravdal, Karsten; Akslen, Lars A.; Frugård, Jannicke; Haukaas, Svein Andreas; Beisland, Christian. 2010. Preliminære resultater av PCA3 måling i urin hos pasienter med cancer prostatae.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2010. Multimodal imaging of differentiated thyroid cancer: FDG-PET-CT, I-131-SPECT-CT and ultrasound.
  • Huuse, Else Marie; Moestue, Siver Andreas; Lindholm, Evita; Bathen, Tone Frost; Nalvoga, Hawa; Bofin, Anna M.; Mælandsmo, Gunhild; Akslen, Lars A.; Engebraaten, Olav; Gribbestad, Ingrid S. 2010. In vivo magnetic resonance imaging and histopathological assessment of tumor microenvironment in luminal-like and basal-like breast cancer xenografts.
  • Reisæter, Lars Anders; Nygård, Yngve; Halvorsen, Ole Johan; Gravdal, Karsten; Rawal, Ravi; Akslen, Lars A.; Haukaas, Svein Andreas; Rørvik, Jarle; Beisland, Christian. 2010. Er preoperativ MR-prostata nyttig for å avklare korrekt T-stadium forut for kirurgi?
  • Reisæter, Lars Anders; Wold, Tor; Haukaas, Svein Andreas; Rørvik, Jarle; Halvorsen, Ole Johan; Akslen, Lars A.; Beisland, Christian. 2010. Er MR-prostata nyttig for å avklare videre oppfølgningsbehov hos pasienter med 2 eller flere negative biopsiserier?
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Li, Wencheng; Lin, Biaoyang; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Jonassen, Inge; Petersen, Kjell; Goldfinger, Naomi; Rotter, Varder; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. Genome-wide profiling of histone H3 lysine 4 and lysine 27 trimethylation reveals an epigenetic signature in prostate carcinogenesis.
  • Ke, Xisong; Li, Wencheng; Qu, Yi; Hovland, Randi; Rostad, Kari; Thorsen, Frits Alan; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2009. EMT Promotes Malignant Transformation of Prostate Epithelial Cells in Culture.
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Goldfinger, Naomi; Rotter, Varda; Akslen, Lars A.; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Polycomb group target genes and bivalent H3K4 & K27me3 modifications in human embryonic cells were enriched among dysregulated genes in prostate cancer.
  • Ke, Xisong; Qu, Yi; Rostad, Kari; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A.; Rotter, Varda; Øyan, Anne Margrete; Kalland, Karl-Henning. 2008. Epithelial to mesenchymal transition of a primary, immortalized prostate cell line is associated with gene expression switches of entire cell attachment modules.
  • Ke, Xisong; Øyan, Anne Margrete; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2007. Functional oncogenomics and epigenomics analysis of prostate cancer.
  • Rostad, Kari; Schlomm, Thorsten; Haukaas, Svein Andreas; Halvorsen, Ole Johan; Øyan, Anne Margrete; Ke, Xisong; Olsen, Sue; Hellwinkel, Olaf JC; Akslen, Lars A.; Kalland, Karl-Henning. 2007. Detection of TMPRSS2:ERG translocations in the urine of prostate cancer patients and identification of ERG target genes.
  • Kalland, Karl-Henning; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2006. Global gene expression analysis of transcription factors in prostate cancer and cell lines.
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2006. ERG upregulation and related transcription factors in prostate cancer.
  • Kalland, Karl-Henning; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Rostad, Kari; Olsen, Sue; Haukaas, Svein Andreas; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Hood, Leroy; Akslen, Lars A. 2004. Gene expression profiling in prostate cancer refined by pairwise comparisons of cDNA microarrays from benign and malignant tissue.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Lin, Biaoyang; Hood, Leroy; Olsen, Sue; Haukaas, Svein Andreas; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2004. Gene expression profiles in prostate cancer: identification of upregulated SIM2 gene validated in archival tissue, relation to histological grading and prognosis.
  • Molven, Anders; Immervold, H; Kugarajh, K; Steine, Solrun; Hoem, Dag; Straume, Oddbjørn; Akslen, Lars A. 2003. Mutation analysis of the RAS-RAF pathway in pancreatic adenocarcinomas and malignant melanomas.
  • Kalland, Karl-Henning; Halvorsen, Ole J.; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Rostad, Kari; Haukaas, Sven; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Jonasen, Inge; Akslen, Lars A.; Hood, Leroy. 2003. Global analysis of gene expression and regulatory patterns in urogenital tumours using DNA microarrays.
  • Kalland, Karl-Henning; Øyan, Anne Margrete; Akslen, Lars A.; Halvorsen, Ole Johan; Bakke, August; Haukaas, Svein Andreas; Bruserud, Øystein; Gjertsen, Bjørn Tore; Ulvestad, Elling; Hellem Bø, Trond; Jonassen, Inge; Hood, Leroy; Lin, Biaoyang; Dimitrov, Krassen; Marzolf, Bruz. 2003. Global analysis of gene expression and regulatory patterns in cancer.
  • Halvorsen, Ole Johan; Øyan, Anne Margrete; Hellem Bø, Trond; Olsen, Sue; Rostad, Kari; Haukaas, Svein Andreas; Bakke, August M; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Gene expression profiling in prostate cancer: cluster analysis and association with tumor differentation.
  • Halvorsen, Ole J.; Øyan, A M; Bø, TH; Olsen, S; Rostad, K; Haukaas, Sven; Bakke, August; Marzolf, B; Dimitrov, K; Lin, B; Jonassen, Inge; Hood, L; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Gene expression profiling in prostate cancer: Cluster analysis and association with tumor differentiation.
  • Halvorsen, Ole J.; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Rostad, Kari; Haukaas, Sven; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Jonasen, Inge; Hood, Leroy; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Gene expression profiling in prostate cancer.
  • Kalland, Karl-Henning; Akslen, Lars A.; Halvorsen, Ole J.; Øyan, A M; Bakke, August; Haukaas, Sven; Bruserud, Øystein; Gjertsen, BT; Ulvestad, Elling; Bø, TH; Jonassen, Inge; Hood, L; Lin, B; Dimitrov, K; Marzolf, B. 2003. DNA microarray studies of human cancer - pitfalls and outlook.
  • Olsen, Sue; Bø, Trond Hellem; Rostad, Kari; Halvorsen, Ole J.; Øyan, Anne Margrete; Haukaas, Sven; Bakke, August; Marzolf, Bruz; Dimitrov, Krassen; Lin, Biaoyang; Hood, Leroy; Jonasen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2003. Comparison of DNA microarray and real time quantitative PCR for quantitation of gene expression of selected genes in prostate cancer.
  • Opsahl, EM; Aas, Turid; Paulsen, Trond Harder; Anker, G; Akslen, Lars A.; Eide, J; Varhaug, Jan Erik. 2002. Cancer mammae behandlet med brystbevarende kirurgi ved Haukeland sykehus 1984-1995.
  • Halvorsen, Ole J.; Haukaas, Sven; Høisæter, Per Åge; Akslen, Lars A. 2001. Prognostisk betydning av angiogenese (microvessel density - MVD) og proliferasjonsmarkøren Ki-67 ved lokalisert prostatacencer.
  • Halvorsen, OJ; Haukaas, Svein Andreas; Høisæter, PÅ; Akslen, Lars A. 1999. Prognostic importance of microvessel density (MVD) in clinically localized prostate cancer.
  • Halvorsen, OJ; Haukaas, Svein Andreas; Høisæter, PÅ; Akslen, Lars A. 1998. Prognostic importance of microvessel density (MVD) in clinically localized prostate cancer.
  • Varhaug, Jan Erik; Boman, Helge; Akslen, Lars A. 1998. Profylaktisk thyroidectomi hos barn - initial erfaring.
  • Hove, LM; Akslen, Lars A. 1998. Malignt melanom på hender.
  • Hove, LM; Akslen, Lars A. 1998. Malignant melanoma of the hand. A 25-year clinico-pathological study.
  • Salvesen, Helga; Iversen, Ole-Erik; Akslen, Lars A. 1997. Independent prognostic importance of microvessel density in endometrial carcinoma. [poster].
  • Rotevatn, S.; Akslen, Lars A.; Bjelke, Erik. 1989. Mortality form ischemic heart disease related to life-style differences among Norwegian men (Abstract).
Vitenskapelig antologi/Konferanseserie
  • Akslen, Lars A.; Watnick, Randolph S. 2017. Biomarkers of the Tumor Microenvironment: Basic Studies and Practical Applications. Springer.
Sammendrag/abstract
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and mitotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Modern Pathology. 50A-50A.
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2013. Proliferation markers PHH3, Ki67 and Mimtotic count all show significant associations with features of aggressive breast carcinomas and reduced survival. Laboratory Investigation. 50A-50A.
  • Tangen, Ingvild Løberg; Krakstad, Camilla; Werner, Henrica Maria Johanna; Øyan, Anne Margrete; Kusonmano, Kanthida; Gilfillan, Siv ; Kalland, Karl-Henning; Akslen, Lars A.; Trovik, Jone; Hurtado, A; Salvesen, Helga Birgitte. 2013. FOXA1 LOSS IN ENDOMETRIAL CANCER IS ASSOCIATED WITH POOR PROGNOSIS AND ER ALPHA LOSS. International Journal of Gynecological Cancer. 1 sider.
  • Knutsvik, Gøril; Stefansson, Ingunn Marie; Collett, Karin; Akslen, Lars A. 2012. Prognostic impact of proliferation markers Ki-67, PHH3 and mitotic count in breast carcinomas. Virchows Archiv. S5-S5.
  • Moestue, Siver Andreas; Flatabø, Silje; Huuse, Else Marie; Lindholm, Evita Maria; Engebraaten, Olav; Maelandsmo, Gunnhild M; Akslen, Lars A.; Gribbestad, Ingrid S. 2012. Metabolic Responses to VEGF Inhibition in Patient-derived Breast Cancer Xenografts. European Journal of Cancer. S32-S32.
  • Nalwoga, Hawa; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2012. Expression of hypoxia-inducible factor-1a and associations with vascular endothelial growth factor expression, high microvessel density and features of aggressive tumors in African breast cancer. Virchows Archiv. S249-S249.
  • Wik, Elisabeth; Rader, Maria; Krakstad, Camilla; Trovik, Jone; Erling, Hoivik; Mjøs, Siv; Stefansson, Ingunn Marie; Kalland, Karl-Henning; Akslen, Lars A.; Salvesen, Helga. 2012. Estrogen receptor a loss in endometrial carcinoma is associated with epithelial-to-mesenchymal transition and a potential for PI3Kinase inhibition. Virchows Archiv. S18-S18.
  • Tiron, Crina Elena; Gjerdrum, Christine; Høiby, Torill; Maugen, Hallvard; Stefansson, Ingunn Marie; Sandal, Tone; Collett, Karin; Li, Shan; McCormack, Emmet Martin; Gjertsen, Bjørn Tore; Micklem, David Robert; Akslen, Lars A.; Glackin, Carlotta A.; Lorens, James. 2011. Axl is an essential epithelial-to-mesenchymal transition-induced regulator of breast cancer metastasis and patient survival. Clinical and Experimental Metastasis. 234-235.
  • Stefansson, Ingunn Marie; Mannelquist, M; Salvesen, HB; Akslen, Lars A. 2010. Prognostic importance of vascular proliferation and tumor cell invasion in blood and lymphatic vessels in endometrial carcinoma. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 248-248.
  • Biermann, Martin; Johnsen, Boel; Naum, Alexandru Gratian; Akslen, Lars A.; Varhaug, Jan Erik; Brauckhoff, Michael. 2010. Multimodal imaging of differentiated thyroid cancer: FDG-PET-CT, I-131-SPECT-CT and ultrasound [Abstract]. European Journal of Nuclear Medicine and Molecular Imaging. S291-S291.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2009. Proliferation of immature tumor vessels is a novel marker of clinical progress in prostate cancer. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 233-233.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2008. Vascular proliferation by Nestin/Ki-67 is a novel predictor of the clinical progress of prostate cancer. Histopathology. 276-277.
  • Arnes, Jarle; Foulkes, William D.; Akslen, Lars A. 2008. Candidate stem cell marker ALDH1 expression and relationship with BRCA-mutations and basal-like differentiation in breast carcinoma. Histopathology. 25-25.
  • Bachmann, Ingeborg M.; Eknes, HE; Otte, Ariel P.; Akslen, Lars A. 2007. Loss of BMI-1 expression is associated with the clinical progress of malignant melanoma. Virchows Archiv. 452-452.
  • Gravdal, Karsten; Halvorsen, Ole Johan; Haukaas, Svein Andreas; Akslen, Lars A. 2007. Epithelial to mesenchymal transition is of strong prognostic importance in prostate cancer. Virchows Archiv. 344-344.
  • Nalwoga, H; Arnes, Jarle; Wabinga, H; Akslen, Lars A. 2007. Basal-like phenotype is frequent in invasive breast carcinoma from Ugandan Africans and is strongly associated with a high expression of EGFR/c-Kit and features of aggressive tumors. Virchows Archiv. 137-137.
  • Kalland, Karl-Henning; Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Olsen, Sue; Haukaas, Svein Andreas; Lin, Biaoyang; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2006. Global gene expression analysis of transcription factors in prostate cancer and cell lines. International Journal of Molecular Medicine. S27.
  • Rostad, Kari; Mannelqvist, Monica; Halvorsen, Ole Johan; Øyan, Anne Margrete; Bø, Trond Hellem; Ulvestad, Elling; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A.; Kalland, Karl-Henning. 2006. ERG upregulation in relation to other transcription factors in prostate cancer. NBS-nytt. 72.
  • Halvorsen, Ole Johan; Rostad, Kari; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Kalland, Karl-Henning; Akslen, Lars A. 2005. Single-minded 2 homolog gene is overexpressed in prostate cancer. Virchows Archiv. 432-432.
  • Kalland, Karl-Henning; Halvorsen, Ole Johan; Rostad, Kari; Mannelqvist, Monica; Øyan, Anne Margrete; Bø, Trond Hellem; Stordrange, Laila; Olsen, Sue; Haukaas, Svein Andreas; Hood, Leroy; Jonassen, Inge; Akslen, Lars A. 2005. Overexpression of ERG and SIM2 transcription factors in prostate cancer. International Journal of Molecular Medicine. S76-S76.
Vitenskapelig oversiktsartikkel/review
  • Geisler, Jürgen; Bachmann, Ingeborg M.; Nyakas, Marta Sølvi; Helsing, Per; Fjøsne, Hans E.; Mæhle, Lovise Olaug; Aamdal, Steinar; Eide, Nils; Svendsen, Henrik Løvendahl; Straume, Oddbjørn; Robsahm, Trude Eid; Dolven-Jacobsen, Kari ; Akslen, Lars A. 2013. Malignt melanom – diagnostikk, behandling og oppfølging i Norge. 2154-2159.
  • Engelsen, Ingeborg Bøe; Akslen, Lars A.; Salvesen, Helga Birgitte. 2009. Biologic markers in endometrial cancer treatment. 693-707.
  • Naumov, George N.; Folkman, Judah; Straume, Oddbjørn; Akslen, Lars A. 2008. Tumor-vascular interactions and tumor dormancy. 569-585.

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