Hjem
Linda Elin Birkhaug Stuhrs bilde

Linda Elin Birkhaug Stuhr

Professor
  • E-postlinda.stuhr@uib.no
  • Telefon+47 55 58 63 86
  • Besøksadresse
    Jonas Lies vei 91
    5009 Bergen
    Rom 
    7A109Y
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Vis forfatter(e) (2022). Intrinsic Differences in Spatiotemporal Organization and Stromal Cell Interactions Between Isogenic Lung Cancer Cells of Epithelial and Mesenchymal Phenotypes Revealed by High-Dimensional Single-Cell Analysis of Heterotypic 3D Spheroid Models. Frontiers in Oncology. 1-24.
  • Vis forfatter(e) (2022). Human organotypic airway and lung organoid cells of bronchiolar and alveolar differentiation are permissive to infection by influenza and SARS-CoV-2 respiratory virus. Frontiers in Cellular and Infection Microbiology. 1-23.
  • Vis forfatter(e) (2021). Human blood serum proteome changes after 6 hours of sleep deprivation at night. Sleep Science and Practice (SSP).
  • Vis forfatter(e) (2019). Stromal integrin α11-deficiency reduces interstitial fluid pressure and perturbs collagen structure in triple-negative breast xenograft tumors. BMC Cancer. 1-13.
  • Vis forfatter(e) (2019). Stromal integrin α11 regulates PDGFR-β signaling and promotes breast cancer progression. Journal of Clinical Investigation. 4609-4628.
  • Vis forfatter(e) (2019). Protein expression profiling of plasma and lungs at different stages of metastatic development in a human triple negative breast cancer xenograft model. PLOS ONE.
  • Vis forfatter(e) (2019). Integrin α11β1 is expressed in breast cancer stroma and associates with aggressive tumor phenotypes. The journal of pathology. Clinical research. 69-82.
  • Vis forfatter(e) (2017). Single factors alone can induce mesenchymal-like morphology, but not promote full EMT in breast cancer cell lines with different hormone statuses. Experimental Cell Research. 257-265.
  • Vis forfatter(e) (2017). Oxygen-dependent regulation of tumor growth and metastasis in human breast cancer xenografts. PLOS ONE. 1-19.
  • Vis forfatter(e) (2017). Imatinib increases oxygen delivery in extracellular matrix-rich but not in matrix-poor experimental carcinoma. Journal of Translational Medicine.
  • Vis forfatter(e) (2017). Hyperbaric oxygen treatment did not significantly affect radiation injury in the mandibular area of rats. Oral surgery, oral medicine, oral pathology and oral radiology. 112-119.
  • Vis forfatter(e) (2017). Fast hyperbaric decompression after heliox saturation altered the brain proteome in rats. PLOS ONE. 1-16.
  • Vis forfatter(e) (2016). The effect of stromal integrin β3-deficiency on two different tumors in mice. Cancers.
  • Vis forfatter(e) (2016). Stromal integrin α11β1 affects RM11 prostate and 4T1 breast xenograft tumors differently. PLOS ONE.
  • Vis forfatter(e) (2015). MRI of the central nervous system in rats following heliox saturation decompression. Undersea & Hyperbaric Medicine. 57-64.
  • Vis forfatter(e) (2015). Bevacizumab treatment induces metabolic adaptation toward anaerobic metabolism in glioblastomas. Acta Neuropathologica. 115-131.
  • Vis forfatter(e) (2015). A rat model of radiation injury in the mandibular area. Radiation Oncology.
  • Vis forfatter(e) (2012). Increased fibrosis and interstitial fluid pressure in two different types of syngeneic murine carcinoma grown in integrin beta 3-subunit deficient mice. PLOS ONE. 10 sider.
  • Vis forfatter(e) (2012). Gene expression in tumor cells and stroma in dsRed 4T1 tumors in eGFP-expressing mice with and without enhanced oxygenation. BMC Cancer. 10 sider.
  • Vis forfatter(e) (2011). Anti-VEGF treatment reduces blood supply and increases tumor cell invasion in glioblastoma. Proceedings of the National Academy of Sciences of the United States of America. 3749-3754.
  • Vis forfatter(e) (2011). A reduction in the interstitial fluid pressure per se, does not enhance the uptake of the small molecular weight compound 5-fluoroacil into 4T1 mammary tumours. Drugs and Theapy Studies.
  • Vis forfatter(e) (2009). Hyperoxic treatment induces mesenchymal to epithelial transition in a rat adenocarcinoma model. PLOS ONE.
  • Vis forfatter(e) (2009). Hyperoxia increases the uptake of 5-FU in mammary tumors independently of cganges in interstitial pressure and tumor stroma. BMC Cancer.
  • Vis forfatter(e) (2009). Combined anti-angiogenic therapy targeting PDGF- and VEGF reseptors lowered the interstitial fluid pressure in a murine experimental carcinoma. PLOS ONE.
  • Vis forfatter(e) (2008). Venous gas emboli in normal and dehydrated rats following decompression from a saturation dive. Aviation, Space and Environmental Medicine. 565-569.
  • Vis forfatter(e) (2008). Peritumoral TNFalpha administration influences tumor stroma structure and physiology independently of growth in DMBA-induced mammary tumours. Scandinavian Journal of Clinical and Laboratory Investigation. 602-611.
  • Vis forfatter(e) (2008). Peritumoral TNF alpha administration influences tumour stroma structure and physiology independently of growth in DMBA-induced mammary tumours. Scandinavian Journal of Clinical and Laboratory Investigation. 602-611.
  • Vis forfatter(e) (2008). CD133 negative glioma cells form tumors in nude rats and give rise to CD133 positive cells. International Journal of Cancer. 761-768.
  • Vis forfatter(e) (2007). Hyperoxia retards growth and induces apoptosis, changes in vascular density and gene expression in transplanted gliomas in nude rats. Journal of Neuro-Oncology. 191-202.
  • Vis forfatter(e) (2007). Hyperoxia retards growth and induces apoptosis and loss of glands and blood vessels in DMBA-induced rat mammary tumors. BMC Cancer. 10 sider.
  • Vis forfatter(e) (2007). Collagen-binding proteoglycan fibromodulin can determine stroma matrix structure and fluid balance in experimental carcinoma. Proceedings of the National Academy of Sciences of the United States of America. 13966-13971.
  • Vis forfatter(e) (2006). No changes in lung function after a saturation dive to 2.5 MPa with intermittent reduction in Po-2 during decompression. European Journal of Applied Physiology. 270-275.
  • Vis forfatter(e) (2006). Inhibition of carcinoma cell-derived VEGF reduces inflammatory characteristics in xenograft carcinoma. International Journal of Cancer. 2795-2802.
  • Vis forfatter(e) (2006). High-dose, short-term, anti-inflammatory treatment with dexamethasone reduces growth and augments the effects of 5-fluorouracil on dimethyl-alpha- benzanthracene-induced mammary tumors in rats. Scandinavian Journal of Clinical and Laboratory Investigation. 477-486.
  • Vis forfatter(e) (2004). Hyperbaric oxygen alone or combined with 5-FU attenuates growth of DMBA-induced rat mammary tumors. Cancer Letters. 35-40.
  • Vis forfatter(e) (1997). The effect of Losartan, an angiotensin II antagonist, on cardiac function, mass and morphology in rats after repeated hyperbaric exposures. Scandinavian Journal of Clinical and Laboratory Investigation. 253-262.
Rapport
  • Vis forfatter(e) (1995). Hvordan påvirkes sirkulasjon av trykk og oksygen. .
Populærvitenskapelig foredrag
  • Vis forfatter(e) (1993). Effekter av simulerte dykk på hjertefunksjonen.
Fagbok
  • Vis forfatter(e) (1994). Øje for øje : en antologi om synet. Det Kongelige Danske Kunstakademi.
Mastergradsoppgave
  • Vis forfatter(e) (2023). Disrupting the metabolic homeostasis of lung cancer to increase the efficacy of immune checkpoint inhibition.
  • Vis forfatter(e) (2021). Human organotypic airway and lung organoids for the study of SARS-CoV-2 infectivity and cytopathology.
  • Vis forfatter(e) (2021). Development and Characterization of an ex vivo Organotypic Non-Small Cell Lung Cancer Model to Study the Effect of Elevated Oxygen Treatment.
  • Vis forfatter(e) (2021). Development and Characterization of an ex vivo Organotypic Non-Small Cell Lung Cancer Model to Study the Effect of Elevated Oxygen Treatment.
  • Vis forfatter(e) (2018). The in vivo effect of integrin α11-deficiency and PDGFR inhibition in breast cancer.
  • Vis forfatter(e) (2016). The effect of hyperbaric oxygen treatment on malignant progression in different breast cancer models in vivo.
  • Vis forfatter(e) (2014). THE EFFECT OF INTEGRIN β3-DEFICIENCY ON 4T1 MAMMARY TUMORS IN MICE.
  • Vis forfatter(e) (2014). Model for Late Radiation Tissue Injury.
  • Vis forfatter(e) (2013). Physical activity and cardiovascular health in the elderly population.
  • Vis forfatter(e) (2012). The effect of hyperbaric oxygen treatment, alone or in combination with 5-FU, on a MDA-MB-231 human mammary tumor model.
  • Vis forfatter(e) (2010). AN eGFP-EXPRESSING IMMUNODEFICIENT MOUSE MODEL WITH dsRED TRANSFECTED MAMMARY TUMOURS, AND THE EFFECT OF HYPERBARIC OXYGEN TREATMENT.
  • Vis forfatter(e) (2008). Simplified detection of dynamic hyperinflation in patients with chronic obstructive pulmonary disease. Validity and reproducibility in a clinic relevant context.
  • Vis forfatter(e) (2007). The effect of hyperbaric oxygen on the tumor interstitium; physiology and structure. A study on DMBA-induced mammary tumors in rats.
Populærvitenskapelig artikkel
  • Vis forfatter(e) (1995). Effekten av simulerte dykk på hjertets funksjon og morfologi. Insicura. 27-28.
Doktorgradsavhandling
  • Vis forfatter(e) (2017). Investigation of different aspects of the tumor microenvironment as determinants of tumor development and progression.
  • Vis forfatter(e) (1993). Cardiovascular changes during moderate hyperbaric exposures. Effect of acute, and repeated hyperbaric exposure, and pharmacological interventions on cardiac functions. (cand.philos).
Poster
  • Vis forfatter(e) (2009). Hyperoxic Treatment induces Mesenchymal-to-Epithelial Transition in a Rat Adenocarcinoma Model.
Vitenskapelig oversiktsartikkel/review
  • Vis forfatter(e) (2014). Corticotropin-releasing factor reduces tumor volume, halts further growth, and enhances the effect of chemotherapy in 4T1 mammary carcinoma in mice. Tumour Biology. 1365-1370.
  • Vis forfatter(e) (2012). Hyperbaric oxygen therapy and cancer-a review. Targeted oncology. 233-242.

Se fullstendig oversikt over publikasjoner i CRIStin.

A rat model for late radiation injury.

Extracellular matrix as determinant of tumor properties.

Hyperbaric oxygen and metastasis.