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Marc Nieres bilde

Marc Niere

Senioringeniør
  • E-postMarc.Niere@uib.no
  • Telefon+47 55 58 68 58
  • Besøksadresse
    Jonas Lies vei 91
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Bockwoldt, Mathias; Houry, Dorothee; Niere, Marc; Gossmann, Toni I.; Reinartz, Ines; Schug, Alexander; Ziegler, Mathias; Heiland, Ines. 2019. Identification of evolutionary and kinetic drivers of NAD-dependent signaling. Proceedings of the National Academy of Sciences of the United States of America. 15957-15966.
  • Van Linden, Magali R; Niere, Marc; Nikiforov, Andrey; Ziegler, Mathias; Dölle, Christian. 2017. Compartment-Specific Poly-ADP-Ribose Formation as a Biosensor for Subcellular NAD Pools. Methods in molecular biology. 45-56.
  • Van Linden, Magali R; Dölle, Christian; Pettersen, Ina Katrine Nitschke; Kulikova, Veronika; Niere, Marc; Agrimi, Gennaro; Dyrstad, Sissel Elisabeth; Palmieri, Ferdinando; Nikiforov, Andrey; Tronstad, Karl Johan; Ziegler, Mathias. 2015. Subcellular distribution of NAD+ between cytosol and mitochondria determines the metabolic profile of human cells. Journal of Biological Chemistry. 27644-27659.
  • Love, Nick R.; Pollak, Nadine; Dölle, Christian; Niere, Marc; Chen, Yaoyao; Oliveri, Paola; Amaya, Enrique; Patel, Sandip; Ziegler, Mathias. 2015. NAD kinase controls animal NADP biosynthesis and is modulated via evolutionarily divergent calmodulin-dependent mechanisms. Proceedings of the National Academy of Sciences of the United States of America. 1386-1391.
  • Kulikova, Veronika; Shabalin, Konstantin; Nerinovski, Kirill; Dölle, Christian; Niere, Marc; Yakimov, Alexander; Redpath, Philip; Khodorkovskiy, Mikhail; Migaud, Marie E.; Ziegler, Mathias; Nikiforov, Andrey. 2015. Generation, release, and uptake of the NAD precursor nicotinic acid riboside by human cells. Journal of Biological Chemistry. 27124-27137.
  • Aksnes, Henriette; Van Damme, Petra; Goris, Marianne; Starheim, Kristian K.; Marie, Michael Bruno Eric; Støve, Svein Isungset; Hoel, Camilla; Kalvik, Thomas Vikestad; Hole, Kristine; Glomnes, Nina; Furnes, Clemens; Ljostveit, Sonja; Ziegler, Mathias; Niere, Marc; Gevaert, Kris; Arnesen, Thomas. 2015. An organellar Nα-acetyltransferase, Naa60, acetylates cytosolic n termini of transmembrane proteins and maintains golgi integrity. Cell reports. 1362-1374.
  • Niere, Marc; Mashimo, Masato; Agledal, Line; Dølle, Christian; Kasamatsu, Atsushi; Kato, Jiro; Moss, Joel; Ziegler, Mathias. 2012. ADP-ribosylhydrolase 3 (ARH3), not poly(ADP-ribose)glycohydrolase (PARG) isoforms, is responsible for degradation of mitochondrial matrix-associated poly(ADP-ribose). Journal of Biological Chemistry. 16088-16102.
  • Nikiforov, Andrey; Dølle, Christian; Niere, Marc; Ziegler, Mathias. 2011. Pathways and Subcellular Compartmentation of NAD Biosynthesis in Human Cells FROM ENTRY OF EXTRACELLULAR PRECURSORS TO MITOCHONDRIAL NAD GENERATION. Journal of Biological Chemistry. 21767-21778.
  • Dølle, Christian; Niere, Marc; Lohndal, Emilia; Ziegler, Mathias. 2010. Visualization of subcellular NAD pools and intra-organellar protein localization by poly-ADP-ribose formation. Cellular and Molecular Life Sciences (CMLS). 433-443.
  • Lau, Corinna; Dølle, Christian; Gossmann, Toni I.; Agledal, Line; Niere, Marc; Ziegler, Mathias. 2010. Isoform-specific targeting and interaction domains in human nicotinamide mononucleotide adenylyltransferases. Journal of Biological Chemistry. 18868-18876.
  • Niere, Marc; Kernstock, Stefan; Koch-Nolte, Friedrich; Ziegler, Mathias. 2008. Functional localization of two poly(ADP-ribose)-degrading enzymes to the mitochondrial matrix. Molecular and Cellular Biology. 814-824.
  • Pollak, Nadine; Niere, Marc; Ziegler, Mathias. 2007. NAD kinase levels control the NADPH concentration in human cells. Journal of Biological Chemistry. 33562-33571.
Vitenskapelig foredrag
  • Niere, Marc; Agledal, Line; Dölle, Christian; Ziegler, Mathias. 2011. ARH3, not PARG isoforms, is responsible for degrading mitochondrial poly-ADP-ribose (PAR), consistent with roles for PARG isoforms different from PAR degradation.
  • Niere, Marc. 2010. Is there poly-ADP-ribose metabolism in mitochondria?
  • Niere, Marc; Dølle, Christian; Agledal, Line; Ziegler, Mathias. 2010. Dissection of candidate enzymes involved in mitochondrial poly-ADP-ribose degradation.
  • Niere, Marc. 2009. Novel human isoforms of poly-ADP-ribose glycohydrolase act outside the mitochondrial matrix.
  • Niere, Marc; Agledal, Line; Ziegler, Mathias. 2009. Is there a poly-ADP-ribose glycohydrolase isoform in mitochondria?
  • Niere, Marc. 2008. Functional analysis of subcellular NAD metabolism by compartment-specific modulation of NAD levels.
  • Niere, Marc. 2007. Unravelling compartment-specific NAD metabolism by utilizing PARP activity.
Short communication
  • Ziegler, Mathias; Niere, Marc. 2004. NAD+ surfaces again. Biochemical Journal. 2 sider.
Sammendrag/abstract
  • Livinskaya, V; Afanasyeva, A; Dölle, Christian; Niere, Marc; Khodorkovskiy, M; Ziegler, Mathias; Nikiforov, Andrey. 2013. Potential role of cytosolic 5'- nucleotidases in human NAD metabolism. The FEBS Journal. 181-181.
  • Mashimo, Masato; Niere, Marc; Agledal, Line; Dölle, Christian; Kasamatsu, Atsushi; Kato, Jiro; Moss, Joel; Ziegler, Mathias. 2012. ARH3 catalyzes degradation of mitochondrial matrix-accumulated Poly (ADP-ribose). The FASEB Journal. 1 sider.
  • Sprater, Florian; Hovden, Arnt-Ove; Niere, Marc; Appel, Silke. 2011. The Epithelial Specific Transcription Factor ESE-3 is Expressed in Immature Dendritic Cells and Occurs Primarily as the ESE-3b Isoform. Scandinavian Journal of Immunology. 366-366.
  • Pollak, Nadine; Niere, Marc; Ziegler, Mathias. 2008. NAD kinase levels control the NADPH concentration in human cells. Free radical research. S37-S37.
Poster
  • Niere, Marc; Lapucci, Andrea; Chiarugi, Alberto; Ziegler, Mathias. 2013. PAR-degrading, but not PAR-generating activities support the idea of PAR metabolism in mitochondria.
  • Agledal, Line; Niere, Marc; Dølle, Christian; Ziegler, Mathias. 2007. Expression of NAD biosynthetic enzymes in response to decreased mitochondrial and cytosolic NAD levels.
  • Niere, Marc; Ramirez-Hernandez, Maria Helena; Ziegler, Mathias. 2006. The utility of PARP-1 activity to modulate subcellular NAD levels.
  • Niere, Marc. 2005. The utility of PARP-1 activity to modulate subcellular NAD levels.
Vitenskapelig oversiktsartikkel/review
  • Strømland, Øyvind; Niere, Marc; Nikiforov, Andrey; Van Linden, Magali R; Heiland, Ines; Ziegler, Mathias. 2019. Keeping the balance in NAD metabolism. 119-130.
  • Agledal, Line; Niere, Marc; Ziegler, Mathias. 2010. The phosphate makes a difference: cellular functions of NADP. 2-10.
  • Lau, Corinna; Niere, Marc; Ziegler, Mathias. 2009. The NMN/NaMN adenylyltransferase (NMNAT) protein family. 410-431.

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