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Universitetet i Bergen
Maria Lie Lotsbergs bilde

Maria Lie Lotsberg

Postdoktor
Institutt for biomedisin
  • E-postMaria.Lie@uib.no
  • Besøksadresse
    Jonas Lies vei 91
    5009 Bergen
    Rom 
    5B104B
  • Postadresse
    Postboks 7804
    5020 Bergen

 

 

Maria Kolnes Lie is doing research on how the tumor microenvironment regulates the epithelial-mesenchymal transition (EMT) by focusing on the Axl tyrosine kinase receptor, and how this relates to cancer therapy responses.

 

 

Vitenskapelig artikkel
  • Vis forfatter(e) (2022). Dissecting the Role of AXL in Cancer Immune Escape and Resistance to Immune Checkpoint Inhibition. Frontiers in Immunology.
  • Vis forfatter(e) (2021). Blocking aerobic glycolysis by targeting pyruvate dehydrogenase kinase in combination with EGFR TKI and ionizing radiation increases therapeutic effect in non-small cell lung cancer cells. Cancers. 24 sider.
  • Vis forfatter(e) (2020). AXL is a driver of stemness in normal mammary gland and breast cancer. iScience. 1-40.
  • Vis forfatter(e) (2020). AXL Targeting Abrogates Autophagic Flux and Induces Immunogenic Cell Death in Drug-Resistant Cancer Cells. Journal of Thoracic Oncology. 973-999.
  • Vis forfatter(e) (2019). Epithelial to mesenchymal transition (EMT) is associated with attenuation of succinate dehydrogenase (SDH) in breast cancer through reduced expression of SDHC. Cancer & Metabolism.
Mastergradsoppgave
  • Vis forfatter(e) (2021). Development and Characterization of an ex vivo Organotypic Non-Small Cell Lung Cancer Model to Study the Effect of Elevated Oxygen Treatment.
Doktorgradsavhandling
  • Vis forfatter(e) (2019). The role of AXL and the microenvironment in cancer cell plasticity and therapy responses. A study in non-small cell lung cancer models.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Vis forfatter(e) (2020). Autophagy mediated danger signaling regulates tumor immunosurveillance and may potentiate the effects of anti-cancer immunotherapy through increased adjuvanticity. 22 sider.
  • Vis forfatter(e) (2017). The Role of Axl Receptor Tyrosine Kinase in Tumor Cell Plasticity and Therapy Resistance. 28 sider.
Vitenskapelig oversiktsartikkel/review
  • Vis forfatter(e) (2020). Decoding cancer’s camouflage: epithelial-mesenchymal plasticity in resistance to immune checkpoint blockade. Cancer Drug Resistance. 22 sider.
  • Vis forfatter(e) (2017). Adaptive mechanisms of resistance to anti-neoplastic agents. MedChemComm. 53-66.
Fagartikkel
  • Vis forfatter(e) (2022). Human Organotypic Airway and Lung Organoid Cells of Bronchiolar and Alveolar Differentiation Are Permissive to Infection by Influenza and SARS-CoV-2 Respiratory Virus. Frontiers in Cellular and Infection Microbiology.

Se fullstendig oversikt over publikasjoner i CRIStin.

 

Born in 1989.

 

2013: M.S. in Nanoscience, University of Bergen. Thesis title: “In vitro phenotypic patterning of vascular cells by nano- and micro-design of the matrix substratum”

 

2014: staff engineer, University of Bergen,The Department of Biomedicine, Cellular Networks Group

 

Since January 2015: PhD student, Cellular Networks Group

 

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