Marion Kusche-Gullbergs bilde

Marion Kusche-Gullberg

  • E-postMarion.Kusche@uib.no
  • Telefon+47 55 58 66 90
  • Besøksadresse
    Jonas Lies vei 91
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Ferreras, Laura; Moles, Anna; Situmorang, Gerhard R.; el Masri, Rana; Wilson, Imogen L.; Cooke, Katie; Thompson, Emily; Kusche-Gullberg, Marion; Vivès, Romain R.; Sheerin, Neil S.; Ali, Simi. 2019. Heparan sulfate in chronic kidney diseases: Exploring the role of 3-O-sulfation. Biochimica et Biophysica Acta - General Subjects. 839-848.
  • Sembajwe, Lawrence Fred; Katta, Kirankumar; Grønning, Mona; Kusche-Gullberg, Marion. 2018. The exostosin family of glycosyltransferases: mRNA expression profiles and heparan sulphate structure in human breast carcinoma cell lines. Bioscience Reports. 1-12.
  • Katta, Kirankumar; Sembajwe, Lawrence Fred; Kusche-Gullberg, Marion. 2018. Potential role for Ext1-dependent heparan sulfate in regulating P311 gene expression in A549 carcinoma cells. Biochimica et Biophysica Acta - General Subjects. 1472-1481.
  • Talsma, Ditmer T.; Katta, Kirankumar; Ettema, Marieke A.B.; Kel, Berna; Kusche-Gullberg, Marion; Daha, Moh R.; Stegeman, Coen A.; van den Born, Jacob; Wang, Lianchun. 2018. Endothelial heparan sulfate deficiency reduces inflammation and fibrosis in murine diabetic nephropathy. Laboratory Investigation. 427-438.
  • Katta, Kirankumar; Imran, Tabasum; Busse-Wicher, Marta; Grønning, Mona; Czajkowski, Szymon; Kusche-Gullberg, Marion. 2015. Reduced expression of EXTL2, a member of the exostosin (EXT) family of glycosyltransferases, in human embryonic kidney 293 cells results in longer heparan sulfate chains. Journal of Biological Chemistry. 13168-13177.
  • Alhasan, Abd A.; Spielhofer, Julia; Kusche-Gullberg, Marion; Kirby, John A.; Ali, Simi. 2014. Role of 6-O-sulfated heparan sulfate in chronic renal fibrosis. Journal of Biological Chemistry. 20295-20306.
  • Lu, Ning; Karlsen, Tine Veronica; Reed, Rolf K.; Kusche-Gullberg, Marion; Gullberg, Donald. 2014. Fibroblast α11β1 integrin regulates tensional homeostasis in fibroblast/A549 carcinoma heterospheroids. PLOS ONE.
  • Reine, Trine M.; Kusche-Gullberg, Marion; Feta, Almir; Jenssen, Trond Geir; Kolset, Svein Olav. 2012. Heparan sulfate expression is affected by inflammatory stimuli in primary human endothelial cells. Glycoconjugate Journal. 67-76.
  • Österholm, Cecilia M.; Lu, Ning; Liden, Åsa; Karlsen, Tine Veronica; Gullberg, Donald; Reed, Rolf K.; Kusche-Gullberg, Marion. 2012. Fibroblast EXT1-levels influence tumor cell proliferation and migration in composite spheroids. PLOS ONE. 10 sider.
  • Kusche-Gullberg, Marion; Nybakken, Kent; Perrimon, Norbert; Lindahl, Ulf. 2012. Drosophila heparan sulfate, a novel design. Journal of Biological Chemistry. 21950-21956.
  • Smeds, Emanuel; Feta, Almir; Kusche-Gullberg, Marion. 2010. Target selection of heparan sulfate hexuronic acid 2-O-sulfotransferase. Glycobiology. 1274-1282.
  • Österholm, Cecilia M.; Barczyk, Malgorzata; Busse, Marta; Grønning, Mona; Reed, Rolf K.; Kusche-Gullberg, Marion. 2009. Mutation in the heparan sulfate biosynthesis enzyme EXT1 influences growth factor signaling and fibroblast interactions with the extracellular matrix. Journal of Biological Chemistry. 34935-34943.
  • Feta, Almir; Do, Kim Anh-Tri; Rentzsch, Fabian; Technau, Ulrich; Kusche-Gullberg, Marion. 2009. Molecular analysis of heparan sulfate biosynthetic enzyme machinery and characterization of heparan sulfate structure in Nematostella vectensis. Biochemical Journal. 585-593.
  • Presto, Jenny; Thuveson, Maria; Carlsson, Pernilla; Busse, Marta; Wilén, Maria; Eriksson, Inger; Kusche-Gullberg, Marion; Kjellen, Lena. 2008. Heparan sulfate biosynthesis enzymes EXT1 and EXT2 affect NDST1 expression and heparan sulfate sulfation. Proceedings of the National Academy of Sciences of the United States of America. 4751-4756.
  • Whiteford, James R; Behrends, Volker; Kirby, Hishani; Kusche-Gullberg, Marion; Muramatsu, Takashi; Couchman, John R. 2007. Syndecans promote integrin-mediated adhesion of mesenchymal cells in two distinct pathways. Experimental Cell Research. 3902-3913.
  • Langsdorf, Aliete; Do, Anh-Tri; Kusche-Gullberg, Marion; Emerson, Charles P. Jr.; Ai, Xingbin. 2007. Sulfs are regulators of growth factor signaling for satellite cell differentiation and muscle regeneration. Developmental Biology. 464-477.
  • Ai, Xingbin ; Kitazawa, Toshio; Do, Anh-Tri; Kusche-Gullberg, Marion; Labosky, Patricia A; Emerson, Charles P. Jr. 2007. SULF1 and SULF2 regulate heparan sulfate-mediated GDNF signaling for esophageal innervation. Development. 3327-3338.
  • Busse, Marta; Feta, Almir; Presto, Jenny; Wilén, Maria; Grønning, Mona; Kjellen, Lena; Kusche-Gullberg, Marion. 2007. Contribution of EXT1, EXT2, and EXTL3 to heparan sulfate chain elongation. Journal of Biological Chemistry. 32802-32810.
  • Ai, Xingbin ; Do, Anh-Tri; Kusche-Gullberg, Marion; Lindahl, Ulf; Lu, Ke; Emerson, Charles P. Jr.; Emerson, CP. 2006. Substrate specificity and domain functions of extracellular heparan sulfate 6-O-endosulfatases, QSulf1 and QSulf2. Journal of Biological Chemistry. 4969-4976.
  • Do, Anh-Tri; Smeds, Emanuel; Spillmann, Dorothe; Kusche-Gullberg, Marion. 2006. Overexpression of heparan sulfate 6-O-sulfotransferases in human embryonic kidney 293 cells results in increased N-acetylglucosaminyl 6-O-sulfation. Journal of Biological Chemistry. 5348-5356.
  • Ledin, J; Ringvall, M; Thuveson, M; Eriksson, I; Wilen, M; Kusche-Gullberg, Marion; Forsberg, E; Kjellen, L. 2006. Enzymatically active N-deacetylase/N-sulfotransferase-2 is present in liver but does not contribute to heparan sulfate N-sulfation. Journal of Biological Chemistry. 35727-35734.
  • Xu, S; Zhao, L; Smeds, E; Kusche-Gullberg, Marion; Venge, P. 2004. Purification of a 75 kDa protein-N-acetylglucosamine-6-sulphatase from the organelle matrix of human neutrophils. Biochemical Journal.
  • Holmborn, K; Ledin, J; Smeds, E; Eriksson, I; Kusche-Gullberg, Marion; Kjellen, L. 2004. Heparan sulfate synthesized by mouse embryonic stem cells deficient in NDST1 and NDST2 is 6-O-sulfated but contains no N-sulfate groups. Journal of Biological Chemistry. 42355-42358.
  • Yamada, S; Busse, M; Ueno, M; Kelly, OG; Skarnes, WC; Sugahara, K; Kusche-Gullberg, Marion. 2004. Embryonic fibroblasts with a gene trap mutation in Ext1 produce short heparan sulfate chains. Journal of Biological Chemistry. 32134-32141.
  • Bodevin-Authelet, S; Kusche-Gullberg, Marion; Pummill, P; Deangelis, P; Lindahl, U. 2004. Biosynthesis of hyaluronan: Direction of chain elongation. Journal of Biological Chemistry.
  • Erusappan, Pugazendhi Murugan. 2012. Molecular mechanisms of integrin alpha 11.
  • Hov, Renate. 2011. Heparan sulfate proteoglycans: effects of NDST1 deficiency on fibroblast function.
  • Sembajwe, Lawrence Fred. 2018. EXT proteins: Role in heparan sulfate Assembly and in Tumor biology.
  • Wadhra, Tabasum Imran. 2011. The Roles of EXT-Like Proteins in Heparan Sulphate Biosynthesis.
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Zeltz, Cedric; Navab, Roya; Kusche-Gullberg, Marion; Tsao, Ming-Sound; Gullberg, Donald. 2017. Role of the Extracellular Matrix in Tumor Stroma: Barrier or Support? 36 sider.
  • Li, J.-P.; Kusche-Gullberg, Marion. 2016. Chapter Six – Heparan Sulfate: Biosynthesis, Structure, and Function. 59 sider.
Vitenskapelig oversiktsartikkel/review
  • Busse-Wicher, Marta; Wicher, Krzysztof B.; Kusche-Gullberg, Marion. 2014. The exostosin family: Proteins with many functions. 25-33.

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