Hjem
Odd André Karlsens bilde
Foto:
Eivind Senneset

Odd André Karlsen

Førsteamanuensis
  • E-postodd.karlsen@uib.no
  • Telefon+47 55 58 46 51
  • Besøksadresse
    Thormøhlens gate 53 A/B
    5006 Bergen
    Rom 
    4H19
  • Postadresse
    Postboks 7803
    5020 Bergen

Min forskningsinteresse handler om å forstå de molekylære mekanismene og prosessene som ligger bak toksisiteten forårsaket av eksponering for miljøgifter, og hvordan dette forplanter seg videre oppover i biologiske nivåer og gir effekter på individ og populasjonsnivå. Forskningen min fokuserer hovedsaklig på marine organismer, og sentrale temaer er hormonforstyrrende stoffer, kjernereseptorer, biomarkører, bioassays, mikroplast, integrativ genomikk, "nye" miljøgifter, og blandingseffekter.

For tiden leder jeg Plastnettverket ved Universitetet i Bergen. Plastnettverket omfavner tverrfaglig forskning om plast i havet. Dette innebærer tilstedeværelse, spredning og effekter av plast og mikroplast, samt den samfunnsvitenskapelige, juridiske og medisinske forskningen omkring plastproblematikken.

Emneansvarlig for BIO216 Toksikologi (emneevaluering)

Veileder i BIO299 Prosjektoppgave i biologi/molekylærbiologi

Foreleser i BIO208 Miljøpåvirkning av oppdrett

Foreleser i BIO316 Utvalgte emner i miljøtoksikologi

Vitenskapelig koordinator for masterretningen Miljøtoksikologi ved institutt for biovitenskap.

Vitenskapelig artikkel
  • Vis forfatter(e) (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. Marine Genomics. 1-13.
  • Vis forfatter(e) (2022). Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). Science of the Total Environment.
  • Vis forfatter(e) (2022). Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). Science of the Total Environment. 17 sider.
  • Vis forfatter(e) (2022). Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). Environment International. 15 sider.
  • Vis forfatter(e) (2021). Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. Polar Biology. 345-358.
  • Vis forfatter(e) (2021). Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. Toxicology in Vitro. 10 sider.
  • Vis forfatter(e) (2021). Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. Environmental Toxicology and Pharmacology. 1-10.
  • Vis forfatter(e) (2021). The chemical defensome of five model teleost fish. Scientific Reports. 1-13.
  • Vis forfatter(e) (2021). Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology. 15123-15135.
  • Vis forfatter(e) (2021). Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. Aquatic Toxicology. 1-11.
  • Vis forfatter(e) (2020). Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua). Aquatic Toxicology. 13 sider.
  • Vis forfatter(e) (2020). Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology. 1033-1044.
  • Vis forfatter(e) (2020). Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua). Aquatic Toxicology. 10 sider.
  • Vis forfatter(e) (2019). Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. Environmental Science and Technology. 7036-7044.
  • Vis forfatter(e) (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Frontiers in Genetics. 1-18.
  • Vis forfatter(e) (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. Marine Environmental Research. 39-51.
  • Vis forfatter(e) (2019). Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. Fish and Shellfish Immunology. 650-658.
  • Vis forfatter(e) (2018). Sequence variations in pxr (nr1i2) from Zebrafish (Danio rerio) strains affect nuclear receptor function. Toxicological Sciences. 28-39.
  • Vis forfatter(e) (2018). RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. Aquatic Toxicology. 174-186.
  • Vis forfatter(e) (2018). LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. Toxicology in Vitro. 332-341.
  • Vis forfatter(e) (2018). Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports. 1-13.
  • Vis forfatter(e) (2018). Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. Chemosphere. 328-339.
  • Vis forfatter(e) (2018). Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. Science of the Total Environment. 1640-1648.
  • Vis forfatter(e) (2017). Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. Aquatic Toxicology. 19-28.
  • Vis forfatter(e) (2016). Transcriptomic profiling of Methylococcus capsulatus (Bath)during growth with two different methane monooxygenases. MicrobiologyOpen. 254-267.
  • Vis forfatter(e) (2016). Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. BMC Genomics. 1-15.
  • Vis forfatter(e) (2016). Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). Fish and Shellfish Immunology. 9-17.
  • Vis forfatter(e) (2016). Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays. Marine Pollution Bulletin. 53-61.
  • Vis forfatter(e) (2014). Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vitro system for studying the effects of environmental contaminants. Aquatic Toxicology. 110-115.
  • Vis forfatter(e) (2014). Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism. BMC Genomics.
  • Vis forfatter(e) (2014). CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. PLOS ONE.
  • Vis forfatter(e) (2014). Alterations in the atlantic COD (Gadus morhua) hepatic thiol-proteome after methylmercury exposure. Journal of Toxicology and Environmental Health, Part A. 650-662.
  • Vis forfatter(e) (2013). Global transcriptome analysis of Atlantic cod (Gadus morhua) liver after in vivo methylmercury exposure suggests effects on energy metabolism pathways. Aquatic Toxicology. 314-325.
  • Vis forfatter(e) (2012). The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. PLOS ONE. 10 sider.
  • Vis forfatter(e) (2012). Mass spectrometric analyses of microsomal cytochrome P450 isozymes isolated from beta-naphthoflavone-treated Atlantic cod (Gadus morhua) liver reveal insights into the cod CYPome. Aquatic Toxicology. 2-10.
  • Vis forfatter(e) (2012). Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics. BMC Genomics. 17 sider.
  • Vis forfatter(e) (2011). Integrative Environmental Genomics of Cod (Gadus morhua): The Proteomics Approach. Journal of Toxicology and Environmental Health, Part A. 494-507.
  • Vis forfatter(e) (2010). Identification of a bacterial di-haem cytochrome c peroxidase from Methylomicrobium album BG8. Microbiology (Reading). 2682-2690.
  • Vis forfatter(e) (2009). Human Naa50p (Nat5/San) Displays Both Protein N-alpha- and N-epsilon-Acetyltransferase Activity. Journal of Biological Chemistry. 31122-31129.
  • Vis forfatter(e) (2008). The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper. Molecular Microbiology. 15-26.
  • Vis forfatter(e) (2008). An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. Journal of Biological Chemistry. 13897-13904.
  • Vis forfatter(e) (2006). Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. Archives of Microbiology. 362-377.
  • Vis forfatter(e) (2005). Identification of a copper-repressible cytochrome c peroxidase of Methylococcus capsulatus (Bath); a member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins. The FEBS Journal. 6324-6335.
  • Vis forfatter(e) (2005). Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). The FEBS Journal. 2428-2440.
  • Vis forfatter(e) (2004). The core 2 ß-1,6-N-acetylglucosaminyltransferase-M encoded by bovine herpesvirus 4 is not essential for virus replication despite contributing to post-translational modifications of structural proteins. Journal of General Virology. 355-367.
  • Vis forfatter(e) (2003). The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. Applied and Environmental Microbiology. 2386-2388.
  • Vis forfatter(e) (2003). Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. Electrophoresis. 757-761.
Rapport
  • Vis forfatter(e) (2021). PW-Exposed Final Report: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species (OC2021 A-107). .
Faglig foredrag
  • Vis forfatter(e) (2022). Complex mixture and omics responses in Atlantic cod: a time- and dose-response study.
  • Vis forfatter(e) (2019). Chemical warfare in the marine environment.
  • Vis forfatter(e) (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
Vitenskapelig foredrag
  • Vis forfatter(e) (2021). Genomic responses to pollutants in Arctic fish and copepod species.
  • Vis forfatter(e) (2020). Polar cod and Goliat: How an oil spill may affect polar cod reproduction.
  • Vis forfatter(e) (2020). Adapting a liver slice culture method for ex vivo toxicological studies in arctic and sub-arctic fish species during sampling cruises.
  • Vis forfatter(e) (2020). ANTIESTROGENIC EFFECTS OF BENZO[a]PYRENE REVEALED BY TRANSCRIPTOME ANALYSIS IN POLAR COD LIVER SLICE CULTURE.
  • Vis forfatter(e) (2020). A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • Vis forfatter(e) (2019). Toxicogenomic responses in Atlantic cod (Gadus morhua) after treatment with selected environmental contaminants in vivo and ex vivo.
  • Vis forfatter(e) (2019). The chemical defensome of Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2019). In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Conference talk.
  • Vis forfatter(e) (2019). EFFECTS OF SELECTED ENVIRONMENTAL ESTROGENS ON EXPRESSION OF FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY GENES IN THE LIVER OF ATLANTIC COD (GADUS MORHUA) IN VIVO AND EX VIVO.
  • Vis forfatter(e) (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • Vis forfatter(e) (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
  • Vis forfatter(e) (2019). Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices.
  • Vis forfatter(e) (2019). Agricultural pesticides in aquafeeds might harm wild fish feeding on leftover pellets near fish farms.
  • Vis forfatter(e) (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA).
  • Vis forfatter(e) (2018). The nuclear receptor complement of Atlantic cod (Gadus morhua) as potential targets for endocrine disrupting compounds.
  • Vis forfatter(e) (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
  • Vis forfatter(e) (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
  • Vis forfatter(e) (2018). Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human.
  • Vis forfatter(e) (2018). Modelling the chemical defensome network - a dynamic visualisation of the involved genes and pathways in two fish species and humans .
  • Vis forfatter(e) (2018). Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans.
  • Vis forfatter(e) (2018). Establishing a cellfree method for xenobiotic detection using ligand activated receptors from the Atlantic cod, Gadus morhua.
  • Vis forfatter(e) (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • Vis forfatter(e) (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • Vis forfatter(e) (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • Vis forfatter(e) (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
  • Vis forfatter(e) (2018). Agonistic and antagonistic effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
  • Vis forfatter(e) (2017). PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT.
  • Vis forfatter(e) (2017). Integrative transcriptome and proteome analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153.
  • Vis forfatter(e) (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
  • Vis forfatter(e) (2017). CHARACTERIZATION OF THE ARYL HYDROCARBON RECEPTORS AHR1B AND AHR2 IN ATLANTIC COD (GADUS MORHUA).
  • Vis forfatter(e) (2016). Toxicogenomics as a tool for understanding responses to pollutants in organisms: Using Atlantic cod (Gadus morhua) and a systems biology approach to environmental toxicology.
  • Vis forfatter(e) (2016). Integrative -omics analyses reveal perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) exposed to the persistent organic pollutant PCB 153.
  • Vis forfatter(e) (2016). Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor.
  • Vis forfatter(e) (2014). ALTERATIONS IN THE HEPATIC PROTEOME OF POLAR COD (BOREOGADUS SAIDA) AFTER DIETARY EXPOSURE TO BENZO[A]PYRENE.
  • Vis forfatter(e) (2011). Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.
  • Vis forfatter(e) (2003). The expression of the surface associated MopE protein of Methylococcus capsulatus (Bath) is regulated by the concentration of copper in the growth medium.
  • Vis forfatter(e) (2003). Proteome studies on the methanotrophic bacterium Methylococcus capsulatus (Bath).
  • Vis forfatter(e) (2003). Multiple polypeptide forms observed in twodimensional gels of Methylococcus capsulatus (Bath)polypeptides are generated during the separation procedure.
  • Vis forfatter(e) (2002). Initial proteome studies of Methylococcus capsulatus (Bath).
Hovedfagsoppgave
  • Vis forfatter(e) (2005). A study of McHr – a novel prokaryotic hemerythrin from Methylococcus capsulatus (Bath).
  • Vis forfatter(e) (2004). Studies of Methylococcus capsulatus (Bath): The surface associated protein SapE.
  • Vis forfatter(e) (2001). The proteome of Methylococcus capsulatus; An initial study by two-domentional gel electrophoresis.
Kronikk
  • Vis forfatter(e) (2018). Torsken manglar eit viktig gen i forsvaret mot miljøgifter. Forskning.no.
Doktorgradsavhandling
  • Vis forfatter(e) (2019). Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta).
  • Vis forfatter(e) (2005). Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath).
Sammendrag/abstract
  • Vis forfatter(e) (2012). Integrative environmental genomics of cod (Gadus morhua) reveal the mechanisms underlying MeHg- and PCB153 induced toxicity. Comparative Biochemistry and Physiology A. S49-S49.
  • Vis forfatter(e) (2010). iCod: Integrative environmental genomics of cod (Gadus morhua); the proteomics approach. Comparative Biochemistry and Physiology A. S44-S44.
  • Vis forfatter(e) (2010). The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. The FEBS Journal. 185-185.
  • Vis forfatter(e) (2010). Human Naa50p (Nat5/San) displays both protein N-alpha- and N-epsilon-Acetyltransferase activity. The FEBS Journal. 182-182.
Poster
  • Vis forfatter(e) (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene.
  • Vis forfatter(e) (2022). Reproductive development in polar cod (Boreogadus saida) exposed to crude oil and food variability.
  • Vis forfatter(e) (2021). Development of a battery of Atlantic cod receptor-based reporter bioassays for assessing environmental toxicity of sediments and chemicals.
  • Vis forfatter(e) (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
  • Vis forfatter(e) (2019). THE CHEMICAL DEFENSOME OF ATLANTIC COD (GADUS MORHUA): HOW DOES IT DIFFER FROM DEFENSOME NETWORKS IN OTHER TELEOST SPECIES?
  • Vis forfatter(e) (2019). Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2019). In vitro assessment of estrogenic effects of bisphenols on Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2019). Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture.
  • Vis forfatter(e) (2019). Chemical warfare in the aquatic environment - The chemical defensome networks of model fish species.
  • Vis forfatter(e) (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) .
  • Vis forfatter(e) (2019). Assessment of produced water toxicity using in vitro tools developed from Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2018). PW-Exposed: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species.
  • Vis forfatter(e) (2018). MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human.
  • Vis forfatter(e) (2018). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2018). Effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
  • Vis forfatter(e) (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
  • Vis forfatter(e) (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
  • Vis forfatter(e) (2017). dCod 1.0 decoding the systems toxicology of Atlantic cod.
  • Vis forfatter(e) (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2017). Using precision cut liver slices (PCLS) for studying effects of environmental contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • Vis forfatter(e) (2017). Studying estrogenic effects of environmental pollutants by using the Atlantic cod (Gadus morhua) estrogen receptor α and a reporter gene assay.
  • Vis forfatter(e) (2017). Peroxisome proliferator-activated receptors (PPARs) as tools for studying effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • Vis forfatter(e) (2017). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • Vis forfatter(e) (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • Vis forfatter(e) (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
  • Vis forfatter(e) (2016). Using precision-cut liver slices (PCLS) and luciferase reporter gene assay to characterize the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
  • Vis forfatter(e) (2016). Systems Toxicology Studies to Investigate Mechanisms of Toxicity of Environmental Chemicals Using Atlantic cod (Gadus morhua) as a Model Organism.
  • Vis forfatter(e) (2016). Peroxisome proliferator-activated receptors (PPARs) as tools to study effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
  • Vis forfatter(e) (2016). Integrated analysis of transcriptome and proteome reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with the persistent organic pollutant PCB 153 .
  • Vis forfatter(e) (2016). Effektar på lipidmetabolismen til atlanterhavstorsk (Gadus morhua) etter eksponering mot enkeltsambindingar og blandingar av miljøgiftar.
  • Vis forfatter(e) (2014). Alterations in the hepatic proteome of polar cod (Boreogadus saida) after dietary exposure to benzo(a)pyrene .
  • Vis forfatter(e) (2012). Integrative environmental genomics of Atlantic cod (Gadus morhua): exposure of cod liver slices to environmental contaminants.
  • Vis forfatter(e) (2010). Human Naa50p (Nat5/San) Displays Both Protein Na-and Ne-Acetyltransferase activity.
  • Vis forfatter(e) (2004). Surface proteins of M. capsulatus (Bath) possibly involved in copper uptake.
  • Vis forfatter(e) (2004). Copper-regulation of some surface-exposed and secreted proteins of the methane-oxidizing bacterium Methylococcus capsulatus (Bath).
  • Vis forfatter(e) (2004). Copper homeostasis in Methylococcus capsulatus.
  • Vis forfatter(e) (2004). An introduction to copper homeostasis in Methylococcus capsulatus.
  • Vis forfatter(e) (2003). Identification of the ORF upstream of MopE in Methylococcus capsulatus.
  • Vis forfatter(e) (2003). Differential expression in sMMO and pMMO producing cells of Methylococcus capsulatus (Bath).
  • Vis forfatter(e) (2002). Initial proteome studies on Methylococcus capsulatus (Bath).
  • Vis forfatter(e) (2002). Characterization of copper-repressible extracellular protein of Methylococcus capsulatus (Bath).
Vitenskapelig oversiktsartikkel/review
  • Vis forfatter(e) (2011). The copper responding surfaceome of Methylococccus capsulatus Bath. FEMS Microbiology Letters. 97-104.
  • Vis forfatter(e) (2011). Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. Methods in Enzymology. 63-79.
  • Vis forfatter(e) (2011). METHANOTROPH OUTER MEMBRANE PREPARATION. Methods in Enzymology. 167-176.

Se fullstendig oversikt over publikasjoner i CRIStin.

2023-2027; Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches – Marma-detox (RCN), WP-leader

2023-2027; Reproductive toxicity and generational effects of a contaminant mixture in fish (ToxiGen)(RCN), Partner

2021-2025;  Effects of antifouling copper coating in aquaculture – implications for fish health, performance and sustainability of production (CAPS)(RCN 325849), WP-leader

2020-2024; Distribution, fate and effects of microplastics in the appendicularian zooplankton Oikopleura dioica (UiB), PI

2021; dCod Pollution Sensing Kit (RCN 323092), Partner

2020-2023; Joint evaluation and mitigation of emerging contaminant risks (INTPART)(RCN (309476), WP-leader

2020-2022; Cellular responses to contaminant exposure in marine mammals from the Arctic (The FRAM-centre), Partner 
   
2020; 8th Norwegian Environmental Toxicology Symposium (NETS) – Ocean Health in the Anthropocene (RCN 311098), PI

2018-2021; Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species (PW-EXPOSED)(RCN 280511), WP-leader

2016-2021; dCod 1.0 – decoding the systems toxicology of Atlantic cod (Gadus morhua)(RCN(248840), WP-leader

2015-2019; iCod 2.0 - integrative environmental genomics of Atlantic cod (Gadus morhua)(RCN 244564), PI

2015-2019; Network for improving research based higher education in basic and applied microbiology( EURASIA, PEA-LT-2016/10095), Partner

2015-2016; In vitro fish: New 3D models for nutritional and toxicological research RCN (244507), Partner

2009-2013; iCod – integrative envionmental genomics of cod (Gadus morhua)(RCN (92441) , PI

 2005; Philosophiae Doctor (PhD) i molekylærbiologi. Tittel på avhandling: ”Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath)”. Molekylærbiologisk institutt, Universitetet i Bergen, Norge

2001; Candidatus scientiarum i molekylærbiologi. Tittel på hovedfagsoppgave: ”The proteome of Methylococcus capsulatus (Bath); An initial study by two-dimensional gel electrophoresis”. Molekylærbiologisk institutt, Universitetet i Bergen, Norge

1998; 35 vektall fra programmet "Høyskolekandidat i bioteknologi". Høyskolen i Hedmark, Hamar, Norge

Yadetie F, Brun NR, Giebichenstein J, Dmoch K, Hylland K, Borgå K, Karlsen OA, Goksøyr A. Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. Mar Genomics. 2022 Aug 12;65:100981. doi: 10.1016/j.margen.2022.100981

Søderstrøm S, Lille-Langøy R, Yadetie F, Rauch M, Milinski A, Dejaegere A, Stote RH, Goksøyr A, Karlsen OA*. Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). Environ Int. 2022 May;163:107203. doi: 10.1016/j.envint.2022.107203.

Strobel A, Lille-Langøy R, Segner H, Burkhardt-Holm P, Goksøyr A, Karlsen OA. Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. Polar Biol. 2022;45(2):345-358. doi: 10.1007/s00300-021-02992-4

Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A. Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). Sci Total Environ. 2022 Mar 25;814:152732. doi: 10.1016/j.scitotenv.2021.152732.

Lille-Langøy R, Jørgensen KB, Goksøyr A, Pampanin DM, Sydnes MO, Karlsen OA*. Substituted Two- to Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environ Sci Technol. 2021 Nov 16;55(22):15123-15135. doi: 10.1021/acs.est.1c02946

Aranguren-Abadía L, Yadetie F, Donald CE, Sørhus E, Myklatun LE, Zhang X, Lie KK, Perrichon P, Nakken CL, Durif C, Shema S, Browman HI, Skiftesvik AB, Goksøyr A, Meier S, Karlsen OA*. Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). Sci Total Environ. 2022 Feb 10;807(Pt 1):150697. doi: 10.1016/j.scitotenv.2021.150697.

Goksøyr SØ, Goldstone J, Lille-Langøy R, Lock EJ, Olsvik PA, Goksøyr A, Karlsen OA*. Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. Aquat Toxicol. 2021 Jul 16;238:105914. doi: 10.1016/j.aquatox.2021.105914

Goksøyr SØ, Sørensen H, Grøsvik BE, Pampanin DM, Goksøyr A, Karlsen OA*. Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. Environ Toxicol Pharmacol. 2021 Oct;87:103704. doi: 10.1016/j.etap.2021.103704.

Yadetie F, Brun NR, Vieweg I, Nahrgang J, Karlsen OA, Goksøyr A. Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. Toxicol In Vitro. 2021 Sep;75:105193. doi: 10.1016/j.tiv.2021.105193.

Eide M, Zhang X, Karlsen OA, Goldstone JV, Stegeman J, Jonassen I, Goksøyr A. The chemical defensome of five model teleost fish. Sci Rep. 2021 May 18;11(1):10546. doi: 10.1038/s41598-021-89948-0
 

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