- E-postO.Oppegaard@uib.no
- BesøksadresseHaukeland universitetssykehus, Laboratoriebygget5009 Bergen
- PostadressePostboks 78045020 Bergen
Oddvar Oppegaard er overlege ved Infeksjonsseksjonen, Medisinsk Klinikk, Haukeland Universitetssjukehus og 1. amanuensis ved Klinisk institutt 2, UiB. Det viktige forskningsfeltet har vært alvorlige streptokokkinfeksjoner med hovedfokus på bakteriell virulens, resistens og patogenese. Arbeidet omfatter bioinformatisk helgenomanalyse, samt genetisk karakterisering og manipulasjon av bakterielle stammer i laboratoriet. For tiden deltar Oppegaard og streptokokkforskningsgruppen ved Universitetet i Bergen og Haukeland universitetssykehus i PERMIT- og PERAID-prosjektene (https://permedinfect.com/) finansiert av Nordforsk og EU. Disse prosjektene har som mål å fremme forskning på persontilpasset medisin (PM) ved alvorlige infeksjonssykdommer, spesielt livstruende nekrotiserende bløtvevsinfeksjoner (NSTI) og sepsis.
Vitenskapelig artikkel
- (2024). Nekrotiserende bløtdelsinfeksjoner. Tidsskrift for Den norske legeforening.
- (2023). Streptococcus dysgalactiae Bloodstream Infections, Norway, 1999-2021. Emerging Infectious Diseases. 260-267.
- (2023). Genomic epidemiology of Streptococcus dysgalactiae subsp. equisimilis strains causing invasive disease in Norway during 2018. Frontiers in Microbiology. 13 sider.
- (2023). A new pathway for penicillin delabeling in Norway. World Allergy Organization Journal.
- (2022). Case Report: Whole-Genome Sequencing of Serially Collected Haemophilus influenzae From a Patient With Common Variable Immunodeficiency Reveals Within-Host Evolution of Resistance to Trimethoprim-Sulfamethoxazole and Azithromycin After Prolonged Treatment With These Antibiotics. Frontiers in Cellular and Infection Microbiology.
- (2022). Analysis of host-pathogen gene association networks reveals patient-specific response to streptococcal and polymicrobial necrotising soft tissue infections. BMC Medicine.
- (2021). Whole genome sequencing reveals possible host species adaptation of Streptococcus dysgalactiae. Scientific Reports.
- (2021). Molecular detection and genotype characterization of Streptococcus dysgalactiae from sheep flocks with outbreaks of infectious arthritis. Veterinary Microbiology.
- (2020). Risk factors and Predictors of Mortality in Streptococcal Necrotizing Soft-Tissue Infections: A Multicenter Prospective Study. Clinical Infectious Diseases. 293-300.
- (2020). Non-purulent skin and soft tissue infections: predictive power of a severity score and the appropriateness of treatment in a prospective cohort. Infectious Diseases. 361-371.
- (2020). Identification of Streptococcus dysgalactiae using matrix-assisted laser desorption/ionization-time of flight mass spectrometry; refining the database for improved identification. Diagnostic microbiology and infectious disease.
- (2020). Emerging threat of antimicrobial resistance in β-hemolytic streptococci. Frontiers in Microbiology. 1-12.
- (2020). Correlation Between Immunoglobulin Dose Administered and Plasma Neutralization of Streptococcal Superantigens in Patients With Necrotizing Soft Tissue Infections. Clinical Infectious Diseases. 1772-1775.
- (2018). Exploring the arthritogenicity of Streptococcus dysgalactiae subspecies equisimilis. BMC Microbiology. 1-10.
- (2017). Zoonotic necrotizing myositis caused by Streptococcus equi subsp. zooepidemicus in a farmer. BMC Infectious Diseases. 1-8.
- (2017). Emergence of a Streptococcus dysgalactiae subspecies equisimilis stG62647-lineage associated with severe clinical manifestations. Scientific Reports. 1-10.
- (2017). Clinical and molecular characteristics of infective β-hemolytic streptococcal endocarditis. Diagnostic microbiology and infectious disease. 135-142.
- (2016). Temporal trends of β-haemolytic streptococcal osteoarticular infections in western Norway. BMC Infectious Diseases. 1-8.
- (2016). Etiology of cellulitis and clinical prediction of streptococcal disease: A prospective study. Open Forum Infectious Diseases.
- (2016). Early Response in Cellulitis: A Prospective Study of Dynamics and Predictors. Clinical Infectious Diseases. 1034-1041.
- (2015). New tricks from an old cow: infective endocarditis caused by Streptococcus dysgalactiae subsp. dysgalactiae. Journal of Clinical Microbiology. 731-734.
- (2015). Increased cytotoxicity and streptolysin O activity in group G streptococcal strains causing invasive tissue infections. Scientific Reports.
- (2015). Beta-haemolytic group A, C and G streptococcal infections in Western Norway: a 15-year retrospective survey. Clinical Microbiology and Infection (CMI). 171-178.
- (2015). A 35-year-old woman with influenza A-associated thrombotic thrombocytopenic purpura. Blood Coagulation and Fibrinolysis. 469-472.
- (2014). Sequence diversity of sicG among group C and G Streptococcus dysgalactiae subspecies equisimilis isolates associated with human infections in western Norway. European Journal of Clinical Microbiology and Infectious Diseases. 273-277.
- (2013). CD64 as a potential biomarker in septic arthritis. BMC Infectious Diseases. 7 sider.
Leder
- (2017). Unravelling pathogenetic mechanisms of epidemic lineages. Virulence. 1102-1104.
Brev til redaktøren
- (2016). Etiology of cellulitis and the validity of new and old methods. Clinical Infectious Diseases. 954-955.
Doktorgradsavhandling
- (2017). Trends of Streptococcus dysgalactiae subsp. equisimilis infections in western Norway. Insights into clinical and microbial aspects.
Poster
- (2022). An investigation of the competence regulon of Streptococcus dysgalactiae.
- (2022). An investigation of the competence regulon in Streptococcus dysgalactiae by RNA-seq.
- (2022). A study of competence in Streptococcus dysgalactiae by RNA-seq.
Vitenskapelig oversiktsartikkel/review
- (2022). Invasive group A streptococcal disease in pregnant women and young children: a systematic review and meta-analysis. The Lancet Infectious Diseases. 1076-1088.