- E-postralf.kellmann@uib.no
- BesøksadresseHaukeland universitetssykehus, Laboratoriebygget5009 Bergen
- PostadressePostboks 78045020 Bergen
Endocrinology, steroid profiling
- (2021). Bedtime Salivary Cortisol as a Screening Test for Cushing Syndrome in Children. Journal of the Endocrine Society (JES). 1-8.
- (2020). Heterologous expression of an unusual ketosynthase, SxtA, leads to production of saxitoxin intermediates in Escherichia coli. ChemBioChem. 1-6.
- (2020). An ultrasensitive routine LC-MS/MS method for estradiol and estrone in the clinically relevant sub-picomolar range. Journal of the Endocrine Society (JES). 1-15.
- (2018). The short cosyntropin test revisited: new normal reference range using LC-MS/MS. Journal of Clinical Endocrinology and Metabolism (JCEM). 1696-1703.
- (2018). LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. Toxicology in Vitro. 332-341.
- (2018). Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. Chemosphere. 328-339.
- (2017). Simultaneous assay of cortisol and dexamethasone improved diagnostic accuracy of the dexamethasone suppression test. European Journal of Endocrinology (EJE). 705-713.
- (2016). Low β2-adrenergic receptor level may promote development of castration resistant prostate cancer and altered steroid metabolism . OncoTarget. 1878-1894.
- (2011). sxtA-Based Quantitative Molecular Assay To Identify Saxitoxin-Producing Harmful Algal Blooms in Marine Waters. Applied and Environmental Microbiology. 7050-7057.
- (2011). Discovery of Nuclear-Encoded Genes for the Neurotoxin Saxitoxin in Dinoflagellates. PLOS ONE.
- (2010). On the chemistry, toxicology and genetics of the cyanobacterial toxins, microcystin, nodularin, saxitoxin and cylindrospermopsin. Marine Drugs. 1650-1680.
- (2009). Proteomic response of human neuroblastoma cells to azaspiracid-1. Journal of Proteomics. 695-707.
- (2009). Characterisation of the paralytic shellfish toxin biosynthesis gene clusters in Anabaena circinalis AWQC131C and Aphanizomenon sp. NH-5. BMC Biochemistry.
- (2008). Identification of a Saxitoxin Biosynthesis Gene with a History of Frequent Horizontal Gene Transfers. Journal of Molecular Evolution. 526-538.
- (2008). Characterization of the Gene Cluster responsible for Cylindrospermopsin Biosynthesis. Applied and Environmental Microbiology. 716-722.
- (2008). Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria. Applied and Environmental Microbiology. 4044-4053.
- (2007). Biochemical characterisation of paralytic shellfish toxin biosynthesis in vitro. Journal of Phycology. 497-508.
- (2011). Discovery of nucelar-encoded genes for the neurotoxin saxitoxin in dinoflagellates.
- (2011). Discovery of nucelar-encoded genes for the neurotoxin saxitoxin in dinoflagellates.
- (2009). Saxitoxin biosynthesis in organisms from two kingdoms - horizontal gene transfer or parallel evolution?
- (2008). Evolution witihin the genus Alexandrium focusing on toxicity.
- (2007). Alkaloid toxin production by cyanobacteria.
- (2010). Saxitoxin gene identified in dinoflagellates.
- (2008). Protein expression changes in human neuroblastoma cells treated with azaspiracid-1.
- (2009). Identification of a Saxitoxin Biosynthesis Gene with a History of Frequent Horizontal Gene Transfers (vol 67, pg 526, 2008). Journal of Molecular Evolution. 292-292.
- (2010). Biosynthesis and Molecular Genetics of Polyketides in Marine Dinoflagellates. Marine Drugs. 1011-1048.
Se fullstendig oversikt over publikasjoner i CRIStin.
Kellmann R, Mihali TK, Jeon YJ, Pickford R, Pomati F, Neilan BA (2008) Biosynthetic intermediate analysis and functional homology reveal a saxitoxin gene cluster in cyanobacteria. Applied & Environmental Microbiology 74:4044-53
Kellmann R, Michali TK, Neilan BA (2008) Identification of a saxitoxin biosynthesis gene with a history of frequent horizontal gene transfers. J Mol Evol 67:526-38
Kellmann R, Mihali TK, Neilan BA (2008) Identification of a saxitoxin biosynthesis gene that has an evolutionary history with frequent horizontal gene transfer events. Journal of Molecular Evolution 67:526-38
Kellmann R, Mills T, Neilan BA (2006) Functional modelling and phylogenetic distribution of putative cylindrospermopsin biosynthesis enzymes. Journal of Molecular Evolution 62:267-280
Kellmann R, Neilan BA (2007) Biochemical characterisation of paralytic shellfish toxin biosynthesis in vitro. Journal of Phycology 43:497-508
Mihali TK, Kellmann R, Muenchhoff J, Barrow KD, Neilan BA (2008) Characterization of the gene cluster responsible for cylindrospermopsin biosynthesis. Appl Environ Microbiol 74:716-22
Neilan BA, Moffitt MC, Mills T, Kellmann R, Burns BP (2002) Novel options for strategic management of water bodies afflicted by harmful algal blooms: the molecular genetics of cyanobacteria. Water Quality Technology, p 1-17
Neilan BA, Pearson LA, Moffitt MC, Kaebernick M, Mihali TK, Kellmann R, Pomati F (2005) A brief history of the molecular biology and genetics of cyanobacterial toxicity and its future in the age of OMICS Advances in Experimental Medicine and Biology. Springer, p 120-148
Neilan BA, Pearson LA, Moffitt MC, Mihali KT, Kaebernick M, Kellmann R, Pomati F (2008) The genetics and genomics of cyanobacterial toxicity. Adv Exp Med Biol 619:417-52
Pomati F, Kellmann R, Burns BP, Cavaliere R, Neilan BA (2006) Comparative gene expression studies of PSP-toxins producing and non-toxic Anabaena circinalis strains and effects of lidocaine hydrochloride. Environment International 32:734-748
1. The molecular mode of action of azaspiracid
2. Saxitoxin biosynthesis and genomics in organisms from two kingdoms - horizontal gene transfer or parallel evolution?
LC-MS/MS methods hormones
quantitative- and phosphoproteomics
enzymology of secondary metabolite biosynthesis
molecular genetics
aquatic microbiology