Hjem
Rolf Kristian Berges bilde

Rolf Kristian Berge

Professor
  • E-postRolf.Berge@uib.no
  • Telefon+47 55 97 30 98
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • Erikstein, Bjarte Skoe; McCormack, Emmet Martin; Tronstad, Karl Johan; Schwede, Frank; Berge, Rolf Kristian; Gjertsen, Bjørn Tore. 2010. Protein kinase A activators and the pan-PPAR agonist tetradecylthioacetic acid elicit synergistic anti-leukaemic effects in AML through CREB. Leukemia Research. 77-84.
  • Jørgensen, Katarina; Felberg, Hanne Solvang; Berge, Rolf K.; Lægreid, Astrid; Johansen, Berit. 2010. Platelet activating factor stimulates arachidonic acid release in differentiated keratinocytes via arachidonyl non-selective phospholipase A(2). Archives of Dermatological Research. 221-227.
  • Bhurruth-Alcor, Yushma; Røst, Therese Halvorsen; Jørgensen, Michael R; Rajender, Melanie Müller; Skorve, Jon; Berge, Rolf Kristian; Miller, Andrew D. 2010. Novel phospholipid analogues of pan-PPAR activator tetradecylthioacetic acid are more PPARα selective. Bioorganic & Medicinal Chemistry Letters. 1252-1255 .
  • Gudbrandsen, Oddrun Anita; Rodriguez, Enrique; Wergedahl, Hege; Mørk, Sverre; Reseland, Janne E.; Skorve, Jon; Palou, Andreu; Berge, Rolf Kristian. 2009. Trans-10, cis-12-conjugated linoleic acid reduces the hepatic triacylglycerol content and the leptin mRNA level in adipose tissue in obese Zucker fa/fa rats. British Journal of Nutrition. 803-815.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Bohov, Pavol; Berge, Rolf Kristian. 2009. The absorption, distribution and biological effects of a modified fatty acid in its free form and as an ethyl ester in rats. Chemico-Biological Interactions. 227-232.
  • Lovas, K; Rost, TH; Skorve, Jon; Ulvik, Rune Johan; Gudbrandsen, Oddrun Anita; Bohov, Pavol; Wensaas, Andreas J.; Rustan, Arild C.; Berge, Rolf Kristian; Husebye, Eystein Sverre. 2009. Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 304-314.
  • Jorgensen, Michael R.; Bhurruth-Alcor, Yushma; Røst, Therese Halvorsen; Bohov, Pavol; Müller, Melanie; Guisado, Christina; Kostarelos, Kostas; Dyrøy, Endre; Berge, Rolf Kristian; Miller, Andrew D.; Skorve, Jon. 2009. Synthesis and Analysis of Novel Glycerolipids for the Treatment of Metabolic Syndrome. Journal of Medicinal Chemistry. 1172-1179.
  • Alne, Henriette; Thomassen, Magny Skinlo; Sigholt, Trygve; Berge, Rolf Kristian; Rørvik, Kjell-Arne. 2009. Reduced sexual maturation in male post-smolt 1+ Atlantic salmon (Salmo salar L.) by dietary tetradecylthioacetic acid. Aquaculture Research. 533-541.
  • Alne, Henriette; Thomassen, Magny Skinlo; Takle, Harald Rune; Terjesen, Bendik Fyhn; Grammes, Fabian; Oehme, Maike Marlene; Refstie, Ståle; Sigholt, Trygve; Berge, Rolf Kristian; Rørvik, Kjell-Arne. 2009. Increased survival by feeding tetradecylthioacetic acid during a natural outbreak of heart and skeletal muscle inflammation in S0 Atlantic salmon, Salmo salar L. Journal of Fish Diseases. 953-961.
  • Wensaas, Andreas J.; Rustan, Arild C.; Marlene, Just; Rolf K, Berge; Drevon, Christian André; Gaster, Michael. 2009. Fatty Acid Incubation of Myotubes From Humans With Type 2 Diabetes Leads to Enhanced Release of β-Oxidation Products Because of Impaired Fatty Acid Oxidation. Diabetes. 527-535.
  • Syversen, Unni; Stunes, Astrid Kamilla; Gustafsson, Björn; Obrant, Karl J.; Nordsletten, Lars; Berge, Rolf K.; Thommesen, Liv; Reseland, Janne E. 2009. Different skeletal effects of the peroxisome proliferator activated receptor (PPAR)α agonist fenofibrate and the PPARγ agonist pioglitazone. BMC Endocrine Disorders. 13 sider.
  • Løvås, K; Wensaas, AJ; Røst, TH; Rustan, AC; Rokling-Andersen, MH; Skorve, Jon; Caesar, R; Ulvik, RJ; Jensen, J; Kaalhus, O; Bohov, P; Graff, Bjørn Anton; Gudbrandsen, OA; Berge, RK; Husebye, ES; Drevon, CA. 2009. Dietary supplementation of tetradecylthioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed on high-fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Wensaas, Andreas Johansen; Rustan, Arild; Rokling-Andersen, Merethe; Caesar, Robert; Jensen, Jørgen; Kaalhus, O; Graff, BA; Gulbrandsen, OA; Berge, RK; Drevon, Christian A. 2009. Dietary supplementation of tetradecylhioacetic acid increases feed intake but reduces body weight gain and adipose depot sizes in rats fed high fat diets. Diabetes, obesity and metabolism. 1034-1049.
  • Wergedahl, Hege; Gudbrandsen, Oddrun Anita; Røst, Therese Halvorsen; Berge, Rolf Kristian. 2009. Combination of fish oil and fish protein hydrolysate reduces the plasma cholesterol level with a concurrent increase in hepatic cholesterol level in high-fat-fed Wistar rats. Nutrition - The International Journal of Applied and Basic Nutritional Sciences. 98-104.
  • Hafstad, Anne Dragøy; Khalid, Ahmed Murtaz; Hagve, Martin; Lund, trine; Larsen, Terje; Severson, DL; Clarke, Kieran; Berge, Rolf; Aasum, Ellen. 2009. Cardiac peroxisome proliferator-activated receptor-alpha activation causes increased fatty acid oxidation, reducing efficiency and post-ischaemic functional loss. Cardiovascular Research (CVR). 519-526.
  • Fernø, Johan; Vik-Mo, Audun Osland; Jassim, Goran; Håvik, Bjarte; Berge, Kjetil; Skrede, Silje; Gudbrandsen, Oddrun Anita; Waage, Jo Erling Riise; Lunder, Niclas; Mørk, Sverre; Berge, Rolf Kristian; Jørgensen, Hugo A; Steen, Vidar Martin. 2009. Acute clozapine exposure in vivo induces lipid accumulation and marked sequential changes in the expression of SREBP, PPAR, and LXR target genes in rat liver. Psychopharmacology. 73-84.
  • Røst, Therese Halvorsen; Moi, Line Leonore Haugan; Berge, Kjetil; Staels, Bart; Mellgren, Gunnar; Berge, Rolf Kristian. 2009. A pan-PPAR ligand induces hepatic fatty acid oxidation in PPAR alpha-/- mice possibly through PGC-1 mediated PPAR delta coactivation. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 1076-1083.
  • Yndestad, A; Haukeland, John Willy; Dahl, Tuva Børresdatter ; Bjoro, K; Gladhaug, Ivar Prydz; Berge, Christ; Damas, Jan Kristian; Haaland, Terese; Loberg, EM; Linnestad, Paul; Birkeland, Kåre; Konopski, Zbigniew; Halvorsen, B; Berge, Rolf Kristian; Aukrust, P. 2009. A complex role of activin A in non-alcoholic fatty liver disease. American Journal of Gastroenterology. 2196-2205.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Berge, Rolf Kristian. 2009. A casein diet added isoflavone-enriched soy protein favorably affects biomarkers of steatohepatitis in obese Zucker rats. Nutrition - The International Journal of Applied and Basic Nutritional Sciences. 574-580.
  • Bivol, Liliana-Monica; Berge, Rolf Kristian; Iversen, Bjarne Magnus. 2008. Tetradecylthioacetic acid prevents the inflammatory response in two-kidney, one-clip hypertension. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. R438-R447.
  • Bivol, Liliana-Monica; Hultström, Michael; Gudbrandsen, Oddrun Anita; Berge, Rolf Kristian; Iversen, Bjarne Magnus. 2008. Tetradecylthioacetic acid downregulates cyclooxygenase 2 in the renal cortex of two-kidney, one-clip hypertensive rats. American Journal of Physiology. Regulatory Integrative and Comparative Physiology. R1866-R1873.
  • Pettersen, Reidar J.; Salem, Mohamed; Skorve, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2008. Pharmacology and safety of tetradecylthioacetic acid (TTA): phase-1 study. Journal of Cardiovascular Pharmacology. 410-417.
  • Wergedahl, Hege; Berge, Kjetil; Bohov, Pavol; Tronstad, Karl Johan; Madsen, Lise; Berge, Rolf Kristian. 2008. Long term treatment with tetradecylthioacetic acid improves the antioxidant status in obese Zucker (fa/fa) rats. Drug Metabolism Letters. 138-145.
  • Henriksen, Christine; Haugholt, Kristin; Lindgren, Magnus; Aurvåg, Anne Karin; Rønnestad, Arild; Ronnestad, A; Gronn, M; Grønn, Morten; Solberg, Rønnaug; Moen, Atle; Nakstad, Britt; Berge, Rolf Kristian; Smith, Lars; Iversen, Per Ole; Drevon, Christian André. 2008. Improved cognitive development among preterm infants attributable to early supplementation of human milk with docosahexaenoic acid and arachidonic acid. Pediatrics. 1137-1145.
  • Aasum, Ellen; Khalid, Ahmed Murtaz; Gudbrandsen, Oddrun Anita; How, Ole-Jakob; Berge, Rolf; Larsen, Terje. 2008. Fenofibrate modulates cardiac and hepatic metabolism and increases ischemic tolerance in diet-induced obese mice. Journal of Molecular and Cellular Cardiology. 201-209.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Liaset, Bjørn; Espe, Marit; Mørk, Sverre; Berge, Rolf Kristian. 2008. Dietary single cell protein reduces fatty liver in obese Zucker rats. British Journal of Nutrition. 776-785.
  • Dyrøy, Endre; Røst, Therese Halvorsen ; Pettersen, Reidar J.; Halvorsen, Bente; Gudbrandsen, Oddrun Anita; Ueland, Thor; Muna, Ziad Ahmed; Muller, Fredrik; Nordrehaug, Jan Erik; Aukrust, Pål; Berge, Rolf Kristian. 2007. Tetradecylselenoacetic acid, a PPAR ligand with antioxidant, antiinflammatory, and hypolipidemic properties. Arteriosclerosis, Thrombosis and Vascular Biology. 628-634.
  • Kennedy, Sean R.; Bickerdike, Ralph; Berge, Rolf Kristian; Porter, Allen R.; Tocher, Douglas R. 2007. Influence of dietary conjugated linoleic acid (CLA) and tetradecylthioacetic acid (TTA) on growth, lipid composition and key enzymes of fatty acid oxidation in liver and muscle of Atlantic cod (Gadus morhua L.). Aquaculture. 372-382.
  • Gjøen, Tor; Kleveland, Ellen Johanne; Moya-Falcón, Corina; Frøystad, Marianne K.; Vegusdal, Anne; Hvatturn, Erlend; Berge, Rolf Kristian; Ruyter, Bente. 2007. Effects of dietary thia fatty acids on lipid composition, morphology and macrophage function of Atlantic salmon (Salmo salar L.) kidney. Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 103-111.
  • Jensen, Line Rørstad; Berge, Kjetil; Bathen, Tone Frost; Wergedahl, Hege; Schønberg, Svanhild A.; Bofin, Anna; Berge, Rolf Kristian; Gribbestad, Ingrid S. 2007. Effect of dietary tetradecylthioacetic acid on colon cancer growth studied by dynamic contrast enhanced MRI. Cancer Biology & Therapy. 1810-1816.
  • Kuiper, Karel Kier-Jan; Salem, M.; Gudbrandsen, Oddrun Anita; Muna, Ziad Ahmed; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2007. Dose-dependent coronary artery intimal thickening after local delivery of the anti-oxidant tetradecylthioacetic acid from stents. Atherosclerosis. e39-e47.
  • Rørvik, Kjell-Arne; Alne, Henriette; Gaarder, Mari; Ruyter, Bente; Måseide, Niels Petter; Jakobsen, Jan Vidar; Berge, Rolf Kristian; Sigholt, Trygve; Thomassen, Magny Skinlo. 2007. Does the capacity for energy utilization affect the survival of post-smolt Atlantic salmon, Salmo salar L., during natural outbreaks of infectious pancreatic necrosis? Journal of Fish Diseases. 399-409.
  • Bivol, Liliana-Monica; Berge, Rolf Kristian; Iversen, Bjarne Magnus. 2007. Differential effect of tetradecythioacetic acid on the renin-angiotensin system and blood pressure in SHR and 2-kidney, 1-clip hypertension. American Journal of Physiology - Renal, fluid and electrolyte physiology. F839-845.
  • Dyrøy, Endre; Wergedahl, Hege; Skorve, Jon Andreas; Gudbrandsen, Oddrun Anita; Songstad, Jon; Berge, Rolf Kristian. 2006. Thia fatty acids with the sulfur atom in even or odd positions have opposite effects on fatty acid catabolism. Lipids. 169-177.
  • Gudbrandsen, Oddrun Anita; Hultström, Michael; Leh, Sabine; Bivol, Liliana-Monica; Vågnes, Øyvind Brune; Berge, Rolf Kristian; Iversen, Bjarne Magnus. 2006. Prevention of Hypertension and Organ Damage in 2-Kidney, 1-Clip Rats by Tetradecylthioacetic Acid. Hypertension. 460-466.
  • Kleveland, Ellen Johanne; Ruyter, B; Vegusdal, Anne; Sundvold, H; Berge, RK; Gjøen, Tor. 2006. Effects of 3-thia fatty acids on expression of some lipid related genes in Atlantic salmon (Salmo salar L.). Comparative Biochemistry and Physiology - Part B: Biochemistry & Molecular Biology. 239-248.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Mørk, Sverre; Liaset, Bjørn; Espe, Marit; Berge, Rolf Kristian. 2006. Dietary soya protein concentrate enriched with isoflavones reduced fatty liver, increased hepatic fatty acid oxidation and decreased the hepatic mRNA level of VLDL receptor in obese Zucker rats. British Journal of Nutrition. 249-257.
  • Gudbrandsen, Oddrun Anita; Røst, Therese Halvorsen ; Berge, Rolf Kristian. 2006. Causes and prevention of tamoxifen-induced accumulation of triacylglycerol in rat liver. Journal of Lipid Research. 2223-2232.
  • Iversen, Per O.; Sørensen, Dag R.; Tronstad, Karl Johan; Gudbrandsen, Oddrun; Rustan, Arild C.; Berge, Rolf Kristian; Drevon, Christian A. 2006. A bioactively modified fatty acid improves survival and impairs metastasis in preclinical models of acute leukemia. Clinical Cancer Research. 3525-3531.
  • Berge, Rolf Kristian; Tronstad, Karl Johan; Berge, Kjetil; Røst, Therese Halvorsen ; Wergedahl, Hege; Gudbrandsen, Oddrun Anita; Skorve, Jon Andreas. 2005. The metabolic syndrome and the hepatic fatty acid drainage hypothesis. Biochimie. 15-20.
  • Gudbrandsen, Oddrun Anita; Dyrøy, Endre; Bohov, Pavol; Skorve, Jon Andreas; Berge, Rolf Kristian. 2005. The metabolic effects of thia fatty acids in rat liver depend on the position of the sulfur atom. Chemico-Biological Interactions. 71-81.
  • Erichsen, Kari; Milde, Anne Marita; Arslan, Gülen; Helgeland, Lars; Gudbrandsen, Oddrun Anita; Ulvik, Rune Johan; Berge, Rolf Kristian; Hausken, Trygve; Berstad, Arnold. 2005. Low-dose oral ferrous fumarate aggravated intestinal inflammation in rats with DSS-induced colitis. Inflammatory Bowel Diseases. 744-748.
  • Bruserud, Øystein; Tronstad, Karl Johan; Berge, Rolf Kristian. 2005. In vitro culture of human osteosarcoma cell lines: a comparison of functional characteristics for cell lines cultured in medium without and with fetal calf serum. Journal of Cancer Research and Clinical Oncology. 377-384.
  • Sandberg, Maria B; Fridriksson, Jakob; Madsen, Lise; Rishi, Vika; Vinson, Charles; Holmsen, Holm A; Berge, Rolf Kristian; Mandrup, Susanne. 2005. Glucose-induced lipogenesis in pancreatic beta-cells is dependent on SREBP-1. Molecular and Cellular Endocrinology. 94-106.
  • Erichsen, Kari; Ulvik, Rune Johan; Grimstad, Tore; Berstad, Arnold; Berge, Rolf Kristian; Hausken, Trygve. 2005. Effects of ferrous sulphate and non-ionic iron-polymaltose complex on markers of oxidative tissue damage in patients with inflammatory bowel disease. Alimentary Pharmacology and Therapeutics. 831-838.
  • Vegusdal, Anne; Gjøen, Tor; Berge, Rolf Kristian; Thomassen, Magny Skinlo; Ruyter, Bente. 2005. Effect of 18 : 1n-9, 20 : 5n-3, and 22 : 6n-3 on lipid accumulation and secretion by Atlantic salmon hepatocytes. Lipids. 477-486.
  • Glosli, Heidi; Gudbrandsen, Oddrun Anita; Mullen, Antony J.; Rost, TH; Røst, Therese Halvorsen ; Wergedahl, Hege; Prydz, Hans; Aukrust, Pål; Berge, Rolf Kristian. 2005. Down-regulated expression of PPAR alpha target genes, reduced fatty acid oxidation and altered fatty acid composition in the liver of mice transgenic for hTNF alpha. Biochimica et Biophysica Acta - Molecular and Cell Biology of Lipids. 235-246.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Liaset, Bjørn; Espe, Marit; Berge, Rolf Kristian. 2005. Dietary proteins with high isoflavone content or low methionine-glycine and lysine-arginine ratios are hypocholesterolaemic and lower the plasma homocysteine level in male Zucker fa/fa rats. British Journal of Nutrition. 321-330.
  • Fernø, Johan; Ræder, Maria Therese Barøy; Vik-Mo, Audun Osland; Skrede, Silje; Glambek, Marte; Tronstad, Karl Johan; Breilid, Harald; Løvlie, Roger; Berge, Rolf Kristian; Stansberg, Christine; Steen, Vidar Martin. 2005. Antipsychotic drugs activate SREBP-regulated expression of lipid biosynthetic genes in cultured human glioma cells: a novel mechanism of action? The Pharmacogenomics Journal. 298-304.
  • Dyrøy, Endre; Yndestad, Arne; Ueland, Thor; Damås, Jan Kristian; Damas, Jan Kristian; Aukrust, Pål; Berge, Rolf Kristian. 2005. Antiinflammatory effects of tetradecylthioacetic acid involve both peroxisome proliferator-activated receptor alpha-dependent and -independent pathways. Arteriosclerosis, Thrombosis and Vascular Biology. 1364-1369.
  • Ukropec, J; Reseland, JE; Gasperikova, D; Demcakova, E; Madsen, Lise; Berge, Rolf Kristian; Rus, AC; Klimes, I; Drevon, CA; Sebokova, E. 2003. The hypotriglyceridemic effect of dietary n-3 FA is associated with increa beta-oxidation and reduced leptin expression. Lipids. 1023-1029.
  • Aukrust, Pål; Wergedahl, H; Muller, H; Ueland, Thor; Dyrøy, E; Damås, Jan Kristian; Froland, SS; Berge, R. 2003. Immunomodulating effects of 3-thia fatty acids in activated peripheral blood mononuclear cells. European Journal of Clinical Investigation. 426-433.
  • Aukrust, Pål; Muller, Fredrik; Svardal, Asbjørn M.; Ueland, Thor; Berge, Rolf Kristian; Frøland, Stig Sophus. 2003. Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy - potential immunomodulatory effects of antioxidants. Journal of Infectious Diseases. 232-238.
  • Aukrust, P; Müller, F; Svardal, A; Ueland, T; Berge, Rolf Kristian; Frøland, S.S. 2003. Disturbed glutathione metabolism and decreased antioxidant levels in human immunodeficiency virus-infected patients during highly active antiretroviral therapy - potential immunomodulatory effects of antioxidants. JID. 232-238.
  • Madebo, Tesfaye; Lindtjørn, Bernt; Aukrust, Pål; Berge, Rolf Kristian. 2003. Circulating antioxidants and lipid peroxidation products in untreated tuberculosis patients in Ethiopia. American Journal of Clinical Nutrition. 117-122.
  • Madebo, T; Lindtjorn, B; Aukrust, Pål; Berge, Rolf Kristian. 2003. Circulating antioxidants and lipid peroxidation products in untreated tuberculosis patients in Ethiopia. American Journal of Clinical Nutrition. 117-122.
  • Grav, Hans J; Tronstad, Karl J.; Gudbrandsen, Oddrun A.; Berge, Kjetil; Fladmark, Kari E.; Martinsen, Tom C.; Waldum, Helge; Wergedahl, Hege; Berge, Rolf K. 2003. Changed energy state and increased mitochondrial beta-oxidation rate in liver of rats associated with lowered proton electrochemical potential and stimulated uncoupling protein 2 (UCP-2) expression. Journal of Biological Chemistry. 30525-30533.
  • Waagbø, Rune; Hamre, Kristin; Bjerkås, Ellen; Berge, Rolf Kristian; Wathne, Einar; Lie, Ø; Torstensen, Bente. 2003. Cataract formation in Atlantic salmon, Salmo salar L., smolt relative to dietary pro- and antioxidants and lipid levels. Journal of Fish Diseases. 213-229.
  • Waagbo, R; Hamre, K; Bjerkas, E; Berge, Rolf Kristian; Wathne, E; Lie, O; Torstensen, B. 2003. Cataract formation in Atlantic salmon, Salmo salar L., smolt relative to dietary pro- and antioxidants and lipid level. Journal of Fish Diseases. 213-229.
  • Petersen, R.K.; Jørgensen, C; Rustan, A. C.; Frøyland, L.; Muller-Decker, K; Furstenberger, G.; Berge, Rolf Kristian; Kristiansen, K; Madsen, Lise. 2003. Arachidonic acid-dependent inhibition of adipocyte differentiation requires PKA activity and is associated with sustained expression of cyclooxygenases. Journal of Lipid Research. 2320-2330.
  • Madsen, Lise; Petersen, R.K.; Sørensen, Morten B; Jørgensen, C; Hallenborg, Philip; Pridal, Lone; Fleckner, Jan; Amri, EZ-Zoubir; Krieg, Peter; Furstenberger, G.; Berge, Rolf Kristian; Kristiansen, K. 2003. Adipocyte differentiation of 3T3-L1 preadipocytes is dependent on lipoxygenase activity during the initial stages of the differentiation process. Biochemical Journal. 539-549.
  • Madsen, Lise; Guerre-Millo, Michele; Nørgaard Flint, Esben; Berge, Kjetil; Tronstad, Karl Johan; Bergene, Elin; Sebokova, Elena; Rustan, Arild C.; Jensen, Jørgen; Mandrup, Susanne; Kristiansen, Karsten; Klimes, Iwar; Staels, Bart; Berge, Rolf Kristian. 2002. Tetradecylthioacetic acid prevents high fat diet induced adiposity and insulin resistance. Journal of Lipid Research. 742-750.
  • Berge, Rolf Kristian; Skorve, Jon; Tronstad, Karl Johan; Berge, Kjetil; Gudbrandsen, Oddrun; Grav, Hans J. 2002. Metabolic effects of thia fatty acids. Current Opinion in Lipidology. 295-304.
  • Muna, Ziad Ahmed; Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Bohov, Pavol; Skorve, Jon; Berge, Rolf Kristian. 2002. Inhibition of rat lipoprotein oxidation after tetradecylthioacetic acid feeding. Biochemical Pharmacology. 1127-1135.
  • Glosli, Heidi; Tronstad, Karl Johan; Wergedal, Hege; Muller, Fredrik; Asbjørn, Svardal; Aukrust, Pål; Berge, Rolf Kristian; Prydz, Hans Peter B. 2002. Human TNFa in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes. The FASEB Journal.
  • Glosli, Heidi; Tronstad, Karl Johan; Wergedahl, Hege; Müller, Fredrik; Svardal, Asbjørn; Aukrust, Pål; Berge, Rolf Kristian; Prydz, Hans. 2002. Human TNF- alfa in transgenic mice induces differential changes in redox status and glutathione-regulating enzymes. The FASEB Journal. 1450-1452.
  • Duplus, Eric; Glorian, Martine; Tordjman, J; Berge, Rolf Kristian; Forest, Claude. 2002. Evidence for selective induction of phosphoenolpyruvate carboxykinase gene expression by unsaturated and nonmetabolized fatty acids in adipocytes. Journal of Cellular Biochemistry. 651-661.
  • Tronstad, Karl Johan; Bruserud, Øystein; Berge, Kjetil; Berge, Rolf Kristian. 2002. Antiproliferative effects of a non-beta-oxidizable fatty acid, tetradecylthioacetic acid, in native human acute myelogenous leukemia blast cultures. Leukemia. 2292-2301.
  • Elholm, Morten; Hollås, Hanne; Issalene, Carol; Barroso, Joao Filipe Viegas; Berge, Rolf Kristian; Flatmark, Torgeir. 2001. Transient up-regulation of liver mitochondrial thymidine kinase activity in proliferating mitochondria. IUBMB Life - A Journal of the International Union of Biochemistry and Molecular Biology. 99-104.
  • Kuiper, K.; Muna, Ziad; Erga, Knut Ståle; Dyrøy, Endre; Svendsen, Einar; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2001. Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteries. Atherosclerosis. 269-275.
  • Kuiper, Karel Kier-Jan; Muna, Ziad Ahmed; Erga, Knut Ståle; Dyrøy, Endre; Svendsen, Einar; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2001. Tetradecylthioacetic acid reduces stenosis development after balloon angioplasty injury of rabbit iliac arteries. Atherosclerosis. 269-275.
  • Berge, Kjetil; Tronstad, Karl Johan; Nørgaard Flindt, Esben; Høj Rasmussen, Thomas; Madsen, Lise; Kristiansen, Karsten; Berge, Rolf Kristian. 2001. Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways. Carcinogenesis. 1747-1755.
  • Pettersen, Reidar J.; Muna, Ziad Ahmed; Kuiper, Karel Kier-Jan; Svendsen, Einar; Müller, Fredrik; Aukrust, Pål; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2001. Sustained retention of tetradecylthioacetic acid after local delivery reduces angioplasty-induced coronary stenosis in the minipig. Cardiovascular Research (CVR). 306-313.
  • Tronstad, Karl Johan; Berge, Kjetil; Nørgaard Flindt, Esben; Kristiansen, Karsten; Berge, Rolf Kristian. 2001. Optimization of methods and treatment conditions for studying effects of fatty acids on cell growth. Lipids. 305-313.
  • Holm, Torbjørn; Berge, Rolf Kristian; Andreassen, Arne K; Ueland, Thor; Kjekshus, John; Simonsen, Svein; Frøland, Stig; Gullestad, Lars; Aukrust, Pål. 2001. Omega-3 fatty acids enhance tumor necrosis factor-alpha levels in heart transplant recipients. Transplantation. 706-711.
  • Westergaard, Majken; Henningsen, Jeanette; Lyne Svendsen, Morten; Johansen, Claus; Birk Jensen, Uffe; Schrøder, Henrik Daa; Kratchmarova, Irina; Berge, Rolf Kristian; Iversen, Lars; Bolund, Lars; Kragballe, Knud; Kristiansen, Karsten. 2001. Modulation of keratinocyte gene expression and differentiation by PPAR-selective ligands and tetradecylthioacetic acid. Journal of Investigative Dermatology. 702-712.
  • Pettersen, Reidar J.; Kuiper, Karel Kier-Jan; Frøyland, Livar; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2001. Long-term retention of a novel antioxidant sulphur-substituted fatty acid analogue after local delivery in porcine coronary arteries. Scandinavian Cardiovascular Journal. 101-106.
  • Aukrust, Pål; Berge, Rolf Kristian; Ueland, Thor; Aaser, Ellinor; Damås, Jan Kristian; Wikeby, Lisbeth; Brunsvig, Anne; Muller, Fredrik; Forfang, Kolbjørn; Frøland, Stig Sophus; Gullestad, Lars. 2001. Interaction between chemokines and oxidative stress: possible pathogenic role in acute coronary syndromes. Journal of the American College of Cardiology. 485-491.
  • Aukrust, Pål; Berge, Rolf Kristian; Ueland, Thor; Aaser, Ellinor; Damås, Jan Kristian; Wikeby, Lisbeth; Brunsvig, Anne; Muller, Fredrik; Forfang, Kolbjørn; Frøland, Stig; Gullestad, Lars. 2001. Interaction between chemokines and oxidative stress: possible pathogenic role in acute coronary syndromes. Journal of the American College of Cardiology. 485-491.
  • Tronstad, Karl Johan; Berge, Kjetil; Dyrøy, Endre; Madsen, Lise; Berge, Rolf Kristian. 2001. Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status. Biochemical Pharmacology. 639-649.
  • Tronstad, Karl Johan; Berge, Kjetil; Dyrøy, Endre; Madsen, Lise; Berge, Rolf Kristian. 2001. Growth reduction in glioma cells after treatment with tetradecylthioacetic acid: changes in fatty acid metabolism and oxidative status. Biochemical Pharmacology. 639-649.
  • Halvorsen, Bente; Rustan, Arild; Madsen, Lise; Reseland, Janne; Berge, Rolf Kristian; Sletnes, P; Christiansen, Erling N. 2001. Effects of long-chain monounsaturated and n-3 fatty acids on fatty acid oxidation and lipid composition in rats. Annals of Nutrition and Metabolism. 30-37.
  • Elholm, Morten; Dam, Inge; Jørgensen, Claus; Krogsdam, Anne-M; Holst, Dorte; Kratchmarova, Irina; Gottlicher, Martin; Gustafsson, Jan-Åke; Berge, Rolf Kristian; Flatmark, Torgeir; Knudsen, Jens; Mandrup, Susanne; Kristiansen, Karsten. 2001. Acyl-CoA esters antagonize the effects of ligands on peroxisome proliferator-activated receptor alpha conformation, DNA binding, and interaction with Co-factors. Journal of Biological Chemistry. 21410-21416.
  • Müller, F; Svardal, Asbjørn M; Nordøy, I; Berge, Rolf Kristian; Aukrust, P; Frøland, SS. 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • Muller, Fredrik; Svardal, Asbjørn M.; Nordøy, Ingvild; Berge, Rolf Kristian; Aukrust, Pål; Frøland, Stig Sophus. 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-14.
  • Müller, F.; Svardal, A.M.; Nordøy, I.; Berge, Rolf Kristian; Aukrust, P.; Frøland, S. S. 2000. Virological and immunological effects of antioxidant treatment in patients with HIV infection. European Journal of Clinical Investigation. 905-914.
  • Muna, Ziad Ahmed; Bolann, Bjørn Johan; Chen, Xin; Songstad, Jon; Berge, Rolf Kristian. 2000. Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid peroxidation and interact with superoxide radical. Free Radical Biology & Medicine. 1068-1078.
  • Muna, Ziad A.; Bolann, Bjørn Johan; Chen, Xin; Songstad, Jon; Berge, Rolf Kristian. 2000. Tetradecylthioacetic acid and tetradecylselenoacetic acid inhibit lipid eroxidation and interact with superoxide radical. Free Radical Biology & Medicine. 1068-1078.
  • Totland, Geir Kåre; Madsen, Lise; Klementsen, Beate; Vaagenes, Hege; Kryvi, Harald; Hexeberg, Sofie; Berge, Rolf Kristian. 2000. Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. Biology of the Cell. 317-329.
  • Totland, Geir Kåre; Madsen, Lise; Klementsen, Beate; Vaagenes, Hege; Kryvi, Harald; Frøyland, Livar; Hexeberg, Sofie; Berge, Rolf Kristian. 2000. Proliferation of mitochondria and gene expression of carnitine palmitoyltransferase and fatty acyl-CoA oxidase in rat skeletal muscle, heart and liver by hypolipidemic fatty acids. Biology of the Cell. 317-329.
  • Doudin, Khaled I.; Berge, Rolf Kristian; Frøystein, Nils Å.; Songstad, Jon. 2000. Preparation and NMR studies of 3-selenaheptadecanoic and 4-selenaoctadecanoic acid, RSe(CH2)nC(O)OH (R = -C14H29, n = 1 and 2), and their methyl esters. Journal of the Chemical Society. Perkin Transactions 2 (2001). 723-729.
  • Doudin, K.; Berge, Rolf Kristian; Frøystein, Nils Åge; Songstad, Jon. 2000. Preparation and NMR studies of 3-selenaheptadecanoic and 4-selenaoctadecanoic acid, RSe(CH2)nC(O)OH (R = -C14H29, n = 1 and 2), and their methyl esters. Journal of the Chemical Society. Perkin Transactions 2 (2001). 723-729.
  • Guerre-Millo, Michèle; Gervois, Phillippe; Raspé, Eric; Madsen, Lise; Poulain, Philippe; Derudas, Bruno; Herbert, Jean-Marc; Winegar, Deborah A.; Willson, Timothy M; Fruchart, Jean-Charles; Berge, Rolf Kristian; Staels, Bart. 2000. Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adiposity. Journal of Biological Chemistry. 16638-16642.
  • Guerre-Millo, Michèle; Gervois, Phillippe; Raspé, Eric; Madsen, Lise; Poulain, Philippe; Derudas, Bruno; Herbert, Jean-Marc; Winegar, Deborah A.; Willson, Timothy M.; Fruchart, Jean-Charles; Berge, Rolf Kristian; Staels, Bart. 2000. Peroxisome Proliferator-activated Receptor a Activators Improve Insulin Sensitivity and Reduce Adipoisty. Journal of Biological Chemistry. 16638-16642.
  • Elholm, Morten; Garras, Alexis; Neve, Søren; Tornehave, Ditte; Lund, Tommy Byskov; Skorve, Jon; Flatmark, Torgeir; Kristiansen, Karsten; Berge, Rolf Kristian. 2000. Long-chain acyl-CoA esters and acyl-CoA binding protein are present in the nucleus of rat liver cells. Journal of Lipid Research. 538-545.
  • Mansoor, Mohammad A.; Bergmark, Claes; Haswell, Steve; Savage, Ian F.; Evans, Peter H.; Berge, Rolf Kristian; Svardal, Asbjørn; Kristensen, Ole. 2000. Correlation between Plasma Total Homocysteine and Copper in Patients with Peripheral Vascular Disease. Clinical Chemistry. 385-391.
  • Mansoor, Mohammad A; Bergmark, Claes; Haswell, Steve; Savage, Ian F; Evans, Peter H; Berge, Rolf Kristian; Svardal, Asbjørn M; Kristensen, Ole. 2000. Correlation between Plasma Total Homocysteine and Copper in Patients with Peripheral Vascular Disease. Clinical Chemistry. 385-391.
  • Rasepé, E.; Madsen, Lise; Lefebvre, M-M.; Leitersdorf, I.; Gelman, L.; Peinado-Onsurbe, J.; Dallongeville, J.; Fruchart, Jean-Charles; Berge, Rolf Kristian; Staels, B. 1999. Modulation of rat liver apolipoprotein gene expression and serum lipid levels by tetradecylthioacetic acid (TTA) via PPARa activation. Journal of Lipid Research. 2099-2110.
  • Wergedahl, Hege; Madsen, Lise; Dyrøy, Endre; Elholm, M; Stray-Pedersen, A; Frøyland, Livar; Lie, O; Berge, Rolf Kristian. 1999. Methylated eicosapentaenoic acid and tetradecylthioacetic acid: effects on fatty acid metabolism. Biochemical Pharmacology. 1133-1143.
  • Vaagenes, Hege; Madsen, Lise; Dyrøy, Endre; Elholm, Morten; Stray-Pedersen, Agnete; Frøyland, Livar; Lie, Øyvind; Berge, Rolf Kristian. 1999. Methylated eicosapentaenoic acid and tetradecylthioacetic acid: Effects on fatty acid metabolism. Biochemical Pharmacology. 1133-1143.
  • Madsen, Lise; Rustan, Arild C.; Wergedahl, Hege; Berge, Kjetil; Dyrøy, Endre; Berge, Rolf Kristian. 1999. Eicosapentaenoic and docosahexaenoic acid affect mitochondrial and peroxisomal fatty acid oxidation in relation to substrate preference. Lipids. 951-963.
  • Hennuyer, Nathalie; Poulain, Philippe; Madsen, Lise; Berge, Rolf Kristian; Houdebine, Louis-Marie; Branellec, Didier; Fruchart, Jean-Charles; Fiévet, Catherine; Duverger, Nicolas; Staels, Bart. 1999. Beneficial Effects of Fibrates on Apolipoprotein A-I Metabolism Occur Independently of Any Peroxisome Proliferative Response. Circulation. 2445-2451.
  • Madsen, Lise; Berge, Rolf Kristian. 1999. 3-Thia Fatty Acid Treatment, in Contrast to Eicosapentaenoic Acid and Starvation, Induces Gene Expression of Carnitine Palmitoyltransferase-II in Rat Liver. Lipids. 447-456.
  • Hamre, K.; Berge, Rolf Kristian; Lie, Ø. 1998. Turnover of _a-, _g-, and _b-tocopherol and distribution in subcellular and lipoprotein fraction indicate presence of an hepatic tocopherol binding protein in Atlantic salmon (<i>Salmo salar L</i>). Fish Physiology & Biochemistry. 71-83.
  • Willumsen, Nina; Vaagenes, Hege; Holmsen, Holm A; Berge, Rolf Kristian. 1998. On the effect of 2-deuterium- and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal beta-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • Willumsen, N.; Vaagenes, Hege; Holmsen, Holm A; Berge, Rolf Kristian. 1998. On the effect of 2-deuterium and 2-methyl-eicosapentaenoic acid derivatives on triglycerides, peroxisomal _b-oxidation and platelet aggregation in rats. Biochimica et Biophysica Acta. 193-203.
  • Hansen, J. B.; Berge, Rolf Kristian; Nordøy, A.; Bønaa, K. H. 1998. Lipid peroxidation of isolated chylomicrons and oxidative status in plasma after prolonged intake of highly purified eicosapentaenoic (EPA) or docosahecaenoic (DHA) acids. Lipids. 1123-1129.
  • Berntsen, Hildegunn; Ekse, Dagfinn; Netteland, Bjørn; Berge, Rolf Kristian; Svardal, Asbjørn; Johannessen, Dag Clement; Lønning, Per Eystein. 1998. Influence of treatment with aminoglutethimide on plasma and red-blood-cell gluthatione status in breast cancer patients. Cancer Chemotherapy and Pharmacology. 46-52.
  • Vaagenes, Hege; Muna, Ziad A.; Madsen, Lise; Berge, Rolf Kristian. 1998. Hypolipidemic n-3 fatty acids increases the antioxidant defence system to inhibit increased plasma and LDL lipid peroxidation. Lipids. 1131-1137.
  • Søvik, Oddmund; Månsson, J. E.; Bjørke Monsen, Anne Lise; Jellum, E.; Berge, Rolf Kristian. 1998. Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n-3 fatty acids. Journal of Inherited Metabolic Disease. 662-670.
  • Søvik, Oddmund; Månsson, J. E.; Bjørke Monsen, Anne Lise; Jellum, E.; Berge, Rolf Kristian. 1998. Generalized peroxisomal disorder in male twins: Fatty acid composition of serum lipids and response to n -3 fatty acids. Journal of Inherited Metabolic Disease. 662-670.
  • Nordøy, A.; Bønaa, K. H.; Nilsen, H.; Berge, Rolf Kristian; Hansen, J. B.; Ingebretsen, O. C. 1998. Effects of Simvastatin and omega-3 fatty acids on plasma lipoproteins and lipid peroxidation in patients with combined hyperlipidaemia. Journal of Internal Medicine. 163-170.
  • Madsen, Lise; Frøyland, Livar; Dyrøy, Endre; Helland, Kari; Berge, Rolf Kristian. 1998. Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. Journal of Lipid Research. 583-593.
  • Madsen, Lise; Frøyland, Livar; Dyrøy, Endre; Helland, Kari; Berge, Rolf Kristian. 1998. Docosahexaenoic and eicosapentaenoic acids are differently metabolized in rat liver during mitochondria and peroxisome proliferation. Journal of Lipid Research. 583-593.
  • Fiskerstrand, T.; Riedel, Bettina; Ueland, Per Magne; Seetharam, B.; Pezacka, E. H.; Gulati, S.; Bose, S.; Banerjee, R.; Berge, Rolf Kristian; Refsum, Helga. 1998. Disruption of a regulatory system involving cobalamin distribution and function in a methionine-dependent human glioma cell line. Journal of Biological Chemistry. 20180-20184.
  • Fiskerstrand, T.; Reidel, B.; Ueland, Per Magne; Seetharam, B.; Pezacka, E.; Gulati, S.; Bose, S.; Banerjee, R.; Berge, Rolf Kristian; Refsum, H. 1998. Disruption of a Regulatory system Involving Cobalamin distribution and Function in a Methionine-dependent Human glioma Cell Line. Journal of Biological Chemistry. 20180-20184.
  • Frøyland, Livar; Madsen, Lise; Echoff, K. M.; Lie, Ø; Berge, Rolf Kristian. 1998. Carnitine Palmitloyltransferase I, Carnitine Palmityltransferase II, and Acyl-CoA Oxidase Activities in Atlantic Salmon (<i>Salmo slar</i>). Lipids. 923-930.
  • Vaagenes, Hege; Madsen, Lise; Asiedu, D.; Lillehaug, Johan; Berge, Rolf Kristian. 1998. Acute modulation of genes encoding peroxisomal and mitochondrial _b-oxidation enzymes by 3-thia fatty acids. Biochemical Pharmacology. 1571-1582.
  • Hamre, K.; Waagbø, Rune; Berge, Rolf Kristian; Lie, Ø. 1997. Vitamins C and E interact in juvenile Atlantic salmon (Salmo salar, L). Free Radical Biology & Medicine. 137-149.
  • Madsen, Lise; Frøyland, Livar; Grav, H.J; Berge, Rolf Kristian. 1997. Up-regulated _D(9)-desaturase gene expression by hypolipidemic peroxisome-proliferating fatty acids results in increased oleic acid content in liver and VLDL: Accumulation of a _D(9)-desaturated metabolite of tetradecylthioacetic acid. Journal of Lipid Research. 554-563.
  • Muna, Ziad A.; Doudin, K.; Songstad, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian. 1997. Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • Muna, Ziad A.; Doudin, K.; Songstad, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian. 1997. Tetradecylthioacetic acid inhibits the oxidative modification of low density lipoprotein and 8-hydroxydeoxyguanosine formation in vitro. Arteriosclerosis, Thrombosis and Vascular Biology. 3255-3262.
  • Ziad, Muna A.; Doudin, K.; Songstad, Jon; Ulvik, Rune Johan; Berge, Rolf Kristian. 1997. Tetradecylthioacetic Acid Inibits the Oxidative Modification of Low Density Lipoprotein and 8-Hydroxydeoxyguanosine formation in Vitro. Arteriosclerosis, Thrombosis and Vascular Biology.
  • Garras, A.; Elholm, M.; Sleboda, J.; Frøyland, H.; Osmundsen, H.; Berge, Rolf Kristian. 1997. On the effects of thia fatty acid analogues on hydrolases involved in the degradation of metabolisable and non-metabolisable acyl-CoA esters. Xenobiotica. 197-202.
  • Frøyland, Livar; Madsen, Lise; Vaagenes, Hege; Totland, Geir Kåre; Auwerx, J.; Kryvi, Harald; Staels, B; Berge, Rolf Kristian. 1997. Mitochondrion is the principal target for nutritional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • Frøyland, Livar; Madsen, Lise; Vaagenes, H; Totland, Geir Kåre; Auwerx, J; Kryvi, Harald; Staels, B; Berge, Rolf Kristian. 1997. Mitochondrion is the principal target for nutitional and pharmacological control of triglyceride metabolism. Journal of Lipid Research. 183-190.
  • Frøyland, Livar; Vaagenes, Hege; Asiedu, D.K.; Garras, Alexis; Lie, Ø; Berge, Rolf Kristian. 1997. Hypotriacylglycerolemic component of fish oil. Prostaglandins, Leukotrienes and Essential Fatty Acids. 387-388.
  • Willumsen, Nina; Vaagenes, H.; Rustan, A.C.; Grav, H.; Lundquist, M.; Skattebøl, L.; Songstad, Jon; Berge, Rolf Kristian. 1997. Enhanced hepatic faty acid oxidation and unpregulated carnitiue palmitoyl-transferance II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • Willumsen, Nina; Vaagenes, H.; Rustan, A.C.; Grav, H.; Lundquist, M.; Skattebøl, L.; Songstad, Jon; Berge, Rolf Kristian. 1997. Enhanced hepatic fatty acid oxidation and unpregulated carnitinu palmitoyl-transferase II gene expression by methyl 3-tharoctadeca6,9,12,15 - tetraenoate in rats. Journal of Lipid Mediators and Cell Signalling. 115-134.
  • Aukrust, P.; Berge, Rolf Kristian; Müller, F.; Ueland, Per Magne; Svardal, A.M.; Frøland, S.S. 1997. Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 730-790.
  • Aukrust, P.; Berge, Rolf Kristian; Müller, F.; Ueland, Per Magne; Svardal, A.M.; Frøland, S.S. 1997. Elevated plasma levels of reduced homocysteine in common variable immunodeficiency - a marker of enhanced oxidative stress. European Journal of Clinical Investigation. 723-730.
  • Farzaad, A.D.; Frøyland, Livar; Thorsen, Thor Elias; Aakvaag, Asbjørn; Berge, Rolf Kristian. 1997. Eikcosapentaenoic acid and sulphur substituted fatty acid analogues inhibit the proliferation of human breast cancer cells in culture. Breast Cancer Research and Treatment. 229-239.
  • Frøyland, Livar; Madsen, Lise; Sjursen, W.; Garras, Alexis; Lie, Ø.; Songstad, Jon; Rustan, A. C.; Berge, Rolf Kristian. 1997. Effect of 3-thia fatty acids on the lipid composition of rat liver, lipoproteins, and heart. Journal of Lipid Research. 1522-1534.
  • Helleland, Charlotte; Eiane, S.A.; Berge, Rolf Kristian; Holmsen, Holm A; Lillehaug, Johan. 1997. 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • Helleland, Charlotte; Eiane, S.A.; Berge, Rolf Kristian; Holmsen, Holm A; Lillehaug, Johan. 1997. 1-@(Carboxymethylthio@)-tetradecane attenuates PDGF- and TPA-induced c-fos mRNA expression and increases the formation of phosphatidylethanolamine with a shift from less to more polar molecular species in C3H/10 1/2 mouse fibroblasts. Experimental Cell Research. 330-340.
  • Brunvand, Harald; Frøyland, Livar; Westby, Jørgen; Hexeberg, Erik; Berge, Rolf Kristian; Grong, Ketil. 1996. Peroxisomal fatty acid oxidation capacity is more resistant to ischaemic and reperfusion injury than mitochondrial fatty acid oxidation capacity in feline hearts. Acta Physiologica Scandinavica. 133-145.
  • Asiedu, D. K.; Frøyland, Livar; Vaagenes, H.; Lie, Ø.; Demoz, A.; Berge, Rolf Kristian. 1996. Long-term effect of tetradecylthioacetic acid: a study on lipid profile and fatty acid composition and oxidation in different rat organs. Biochimica et Biophysica Acta. 86-96.
  • Willumsen, N.; Vaagenes, H; Lie, Ø.; Berge, Rolf Kristian. 1996. Eicosapentaenoic acid, but not docosahexaenoic acid, increases mitochondrial fatty acid oxidation and upregulates 2,4-dienoyl-CoA reductase gene expression in rats. Lipids. 579-592.
  • Frøyland, Livar; Vaagenes, H.; Asiedu, D. K.; Garras, A.; Lie, Ø.; Berge, Rolf Kristian; Farstad, Marit; Søreide, Odd. 1996. Chronic administration of eicosapentaenoic acid and docosahexaenoic acid as ethyl esters reduced plasma cholesterol and changed fatty acid composition in rat blood and organs. Lipids. 169-178.
  • Brunvand, Harald; Kvitting, Peder; Rynning, Stein Erik; Berge, Rolf Kristian; Grong, Ketil. 1996. Carvedilol protects against lethal reperfusion injury through antiadrenergic mechanisms. Journal of Cardiovascular Pharmacology. 409-417.
  • Brunvand, Harald; Frøyland, Livar; Hexeberg, Erik; Rynning, Stein Erik; Berge, Rolf Kristian; Grong, Ketil. 1996. Carvedilol improves function and reduces infarct size in the feline myocardium by protecting against lethal reperfusion injury. European Journal of Pharmacology. 99-107.
  • Frøyland, Livar; Helland, Knut; Totland, Geir Kåre; Kryvi, Harald; Berge, Rolf Kristian. 1996. A hypolipidemic peroxisome proliferating fatty acid induces polydispersity of rat liver mitochondria. Biology of the Cell. 105-112.
  • Frøyland, Livar; Berge, Rolf Kristian. 1996. 3-Thia fettsyrer - et nytt lipidsenkende legemiddel? NBS-nytt. 6-11.
  • Gedde-Dahl, Ane; Ranheim, Trine; Drevon, Christian A; Skrede, S.; Berge, Rolf Kristian; Rustan, Arild. 1995. Tetradecylthioacetic acid (a 3-thia fatty acid) decreases triacylglycerol secretion in CaCo-2 cells. Journal of Lipid Research. 535-543.
  • Skorve, Jon; Vaagenes, H.; Rosendal, J.; Knudsen, John Chr; Lillehaug, Johan; Berge, Rolf Kristian. 1995. Fatty acid-CoA oxidase activity is induced before long-chain acyl-CoA hydrolase activity and acyl-CoA binding protein in liver of rats treated with peroxisome proliferating 3-thia fatty acids. Xenobiotica. 1181-1194.
  • Hexeberg, S; Willumsen, N; Berge, Rolf Kristian. 1995. Eicosapentaenoic acid causes transient accumalation of lipids in rat myocardium. Biochimica et Biophysica Acta. 341-345.
  • Demoz, A.; Vaagenes, H.; Aareæther, N.; Hvattum, E.; Skorve, Jon; Goettlicher, M.; Lillehaug, Johan; Gibson, G. G.; Gustafsson, J. Å.; Hood, S.; Berge, Rolf Kristian. 1994. Coordinate induction of hepatic fatty acyl-CoA oxidase and P450A1 in rat after activation of the peroxisome proliferator-activated receptor (PPAR) by sulphur-substituted fatty acid analogues. Xenobiotica. 943-954.
  • Willumsen, N.; Skorve, Jon; Hexeberg, S.; Berge, Rolf Kristian. 1993. The hypotriglyceridemic effect of eicosapentaenoic acid in rats is reflected in increased mitochondrial fatty acid oxidation followed by diminished lipogenesis. Lipids. 683-690.
  • Shurbaji, A.; Skorve, Jon; Berge, Rolf Kristian; Rudling, M.; Bjørkheim, I.; Berglund, L. 1993. The effect of 3-thiadicarboxcylic acid on lipid metabolism in experimental nephrosis. Arteriosclerosis and thrombosis. 1580-1586.
  • Demoz, A.; Svardal, A.; Berge, Rolf Kristian. 1993. Relationship between peroxisomes proliferating sulfur substituted fatty acid analogues, heatic lipid peroxidation and hydrogen peroxide metabolism. Biochemical Pharmacology. 257-259.
  • Tollef, P.; Strømstedt, M.; Frøyland, Livar; Berge, Rolf Kristian; Gustafsson, J. A. 1993. Pretranslational regulation of cytochrome P-450 4A1 by free fatty acids in primary cultures of rat hepatocytes. Journal of Lipid Research. 1758-1791.
  • Skorve, Jon; Al-Shurbaji, A.; Asiedu, D. K.; Bjørkheim, I.; Berglund, L.; Berge, Rolf Kristian. 1993. On the mechanism of the hypolipidemic effect on sulfur-substituted hexadecanediotic (3-thiadicarboxylic acid) in normolipidemic rats. Journal of Lipid Research. 1177-1185.
  • Skorve, Jon; Svardal, Asbjørn; Mansoor, M. A.; Berge, Rolf Kristian. 1993. Modulation of phosphatidylcholine biosynthesis by peroxisomal proliferating fatty acid analogs. Lipids. 795-801.
  • Skorve, Jon; Berge, Rolf Kristian. 1993. Hypolipidemic effect of sulfur-substitutet fatty acid analogues in rats fed a high carbohydrate diet. Biochimica et Biophysica Acta (BBA) - Lipids and Lipid Metabolism. 175-183.
  • Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1993. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antioxidant defense in mice. Lipids. 968-971.
  • Asiedu, D. K.; Skorve, Jon; Willumsen, N.; Demoz, A.; Berge, Rolf Kristian. 1993. Early affects on mitocondrial and peroxisomal beta-oxidation by the hypolipidemic 3-thia fatty acid in rat livers. Biochimica et Biophysica Acta. 73-76.
  • Willumsen, N.; Hexeberg, S.; Skorve, Jon; Lundquist, M.; Berge, Rolf Kristian. 1993. Docosahexaenoic Acid Shows no Triglyceride-Lowering Effects, but increases the Peroxisomal Fatty Acid Oxidation in Liver of Rats. Journal of Lipid Research. 13-22.
  • Hexeberg, S.; Willumsen, N.; Rotevatn, S.; Hexeberg, E.; Berge, Rolf Kristian. 1993. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • Hexeberg, S.; Willumsen, N.; Rotevatn, S.; Hexeberg, E.; Berge, Rolf Kristian. 1993. Cholesterol induced lipid accumulation in myocardial cells of rats. Cardiovascular Research (CVR). 442-446.
  • Karwinski, W.; Ulvik, Rune Johan; Farstad, Marit; Svardal, Asbjørn; Berge, Rolf Kristian; Søreide, Odd. 1993. Allupurinol does not affect the concentration of endogenous glutathione in liver cells in rats after 60 min of normothermic liver ischemia. European Journal of Surgery. 355-359.
  • Asiedu, D.; Skorve, Jon; Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1992. Relationship between translocation of long-chain acyl-CoA hydrolase, phosphatidate phosphohydrolase and CTP:Phosphocholine cytidylyltransferase and the synthesis of triglycerides and phosphatidylcholine in rat liver. Lipids. 241-147.
  • Demoz, A.; Willumsen, N.; Berge, Rolf Kristian. 1992. Eicosapentaenoic acid at hypotriglyceridemic dose enhances the hepatic antiocidant defense in mice. Lipids. 968-972.
  • Asiedu, D.; Aarsland, A.; Skorve, R.; Svardal, Asbjørn; Berge, Rolf Kristian. 1990. Fatty acid metabolism in livers of rats treated with hypolipidemic sulphur substituted fatty acid analogues. Role of long-chain acyl-CoA and requirement for stimulated fatty acid oxidation in peroxisomes. Biochimica et Biophysica Acta. 211-221.
  • Hovik, R.; Aarsland, A.; Osmundsen, H.; Bergseth, S.; Bremer, J.; Berge, Rolf Kristian. 1990. Effects of 3- and 4-thia substituted fatty acids on mitochondrial and peroxisomal _b-oxidation. In vivo and in vitro studies. Biochemical Journal. 321-330.
  • Skorve, Jon; Ruyter, Bente; Rustan, Arild; Christiansen, Erling N; Drevon, Christian A; Berge, Rolf Kristian. 1990. Effect of 3- and 4-thia-substituted fatty acids on glycerolipid metabolism and mitochondrial beta-oxidation in rat liver. Biochemical Pharmacology. 2005-2012.
Vitenskapelig foredrag
  • Ahlstrøm, Øystein; Berge, Rolf Kristian; Bjørndal, Bodil; Xue, Chen. 2018. Effect of tetradecylthioacetic acid (TTA) on energy intake and body fat deposition in silver foxes (Vulpes vulpes).
  • Stiksrud, Birgitte; Lorvik, Kristina Berg; Kvale, Dag; Mollnes, Tom Eirik; Ueland, Per Magne; Berge, Rolf Kristian; Trøseid, Marius; Tasken, Kjetil; Dyrhol-Riise, Anne Ma. 2015. Plasma Interferon-inducible Protein 10 Levels, T-cell Activation and Regulation are Increased in HIV Immunological Non-Responders.
  • Khalid, Ahmed Murtaz; Hafstad, Anne Dragøy; Lund, trine; Larsen, Terje; Severson, david lester; Berge, Rolf; Clarke, Kieran; Aasum, Ellen. 2008. Administration of tetradecylthioacetic acid (TTA) in mice accelerates myocardial FA oxidation via increased expression of pparα target genes.
  • Røst, Therese Halvorsen ; Dyrøy, Endre; Pettersen, Reidar J.; Halvorsen, Bente ; Gudbrandsen, Oddrun Anita; Ueland, Thor; Muna, Ziad; Muller, Fredrik; Nordrehaug, Jan Erik; Aukrust, Pål; Berge, Rolf Kristian. 2006. The Antioxidant,Anti-inflammatory and Hypolipidemic Properties of a Seleno-substituted Fatty Acid.
  • Røst, Therese Halvorsen; Mellgren, Gunnar; Berge, Rolf Kristian. 2005. A pan-PPAR ligand induces differential coactivation of PPARs by SRCs and PGC-1.
  • Røst, Therese Halvorsen; Mellgren, Gunnar; Berge, Rolf Kristian. 2004. Tetradecylthioacetic acid induces ligand dependent coactivation of PPARs by PGC-1 and SRC coactivators.
  • Aasum, Ellen; Khalid, Ahmed Murtaz; Gudbrandsen, Oddrun Anita; How, Ole-Jacob; Berge, Rolf; Larsen, Terje. 2004. Different effects of PPAR ligands on cardiac metabolism in mice fed high fat diet.
  • Dyrøy, Endre; Berge, Rolf Kristian. 2004. Decreased TNFα induced endothelial activation in the presence of a new bioactive fatty acid.
  • Arslan, Gülen; Erichsen, Kari; Milde, Anne Marita; Gudbrandsen, Oddrun; Helgeland, Lars; Basu, Simon; Berge, Rolf Kristian; Murison, Robert; Hausken, Trygve; Frøyland, Livar; Berstad, Arnold. 2003. Effects of Omega-3 Fatty Acids on DSS-induced Colitis in Rats.
  • Erichsen, Kari; Gudbrandsen, Oddrun; Arslan, Gülen; Milde, Anne Marita; Helgeland, Lars; Ulvik, Rune Johan; Frøyland, Livar; Berstad, Arnold; Berge, Rolf Kristian; Hausken, Trygve. 2003. Effect of Ferrous Fumarate Supplementation in Dextran Sulfate Sodium Colitis in Rats.
  • Berge, Kjetil; Tronstad, Karl Johan; Nørgaard Flint, Esben; Høj Rasmussen, Thomas; Madsen, Lise; Kristiansen, Karsten; Berge, Rolf Kristian. 2001. Tetradecylthioacetic acid inhibits growth of rat glioma cells ex vivo and in vivo via PPAR-dependent and PPAR-independent pathways.
  • Tronstad, Karl Johan; Berge, Kjetil; Dyrøy, Endre; Madsen, Lise; Berge, Rolf Kristian. 2001. PPAR-activating 3-thia fatty acid influences the growth potential and metabolism in glioma cells.
  • Madsen, Lise; Berge, Rolf Kristian; Guerre-Millo, Michele; Berge, Kjetil; Bergene, Elin; Flindt, Esben N.; Rustan, Arild; Jensen, Jørgen; Sebokova, Elena; Mandrup, Susanne; Kristiansen, Karsten; Klimes, Ivar; Staels, Bart. 2001. Expression of PPARa target genes improve insulin action and reduce adiposity.
  • Holm, Torbjørn; Berge, Rolf Kristian; Andreassen, Arne K.; Ueland, Thor; Kjekshus, John; Simonsen, Svein; Gullestad, Lars; Aukrust, Pål. 2001. Dietary treatment of highly concentrated omega-3 fatty acids increases tumor necrosis factor alpha and reduces antioxidant levels in stable heart transplant recipients.
  • Tronstad, Karl Johan; Gjertsen, Bjorn Tore; Berge, Kjetil; Brustugun, Odd Terje; Døskeland, Stein Ove; Berge, Rolf Kristian. 2001. 3-Thia fatty acid induces mitochondrial alterations and triggers apoptosis in cancer cells.
  • Berge, Rolf Kristian; Madsen, Lise; Guerre-Millo, Michele; Berge, Kjetil; Bergene, Elin; Nørgaard Flint, Esben. 2000. Expression of PPAR alpha target genes improve insulin action and reduce adiposity.
  • Bolann, Bjørn Johan; Chen, Xin; Ulvik, Rune Johan; Berge, Rolf Kristian. 1998. On the antioxidant effect of tetradecylthioacetic acid and tetradecylselenoacetic acid.
  • Tronstad, Karl Johan; Berge, Kjetil; Brustugun, Odd Terje; Bjerkvig, Rolf; Berge, Rolf Kristian. 1998. Metabolic effects of 3-thia fatty acid in cancer cells.
  • Chen, Xin; Bolann, Bjørn Johan; Berge, Rolf Kristian; Ulvik, Rune Johan. 1998. Antioxidant properties of 3-Thia fatty acids.
  • Søvik, Oddmund; Monsen, A. L. B.; Berge, Rolf Kristian; Kryvi, Harald; Jellum, E. 1994. Zellweger-like syndrome: Prolonged survival in male twins during treatment with n-3 fatty acids.
Sammendrag/abstract
  • Rostrup, Espen; Slettom, Grete; Seifert, Reinhard; Berge, Rolf Kristian; Nordrehaug, Jan Erik. 2012. Combined thermal and electrical muscle stimulation reduce visceral fat and improve lipid profile during weight loss. Circulation. E679-E680.
  • Øie, Erik; Ueland, Thor; Dahl, Christen Peder; Bohov, Pavol; Berge, Christ; Yndestad, Arne; Gullestad, Lars; Aukrust, Pål; Berge, Rolf Kristian. 2010. Low circulating eicosatetraenoic acid and high vaccenic acid are associated with disease severity and predict mortality in heart failure. European Heart Journal. 570-570.
  • Khalid, Ahmed Murtaz; Aasum, Ellen; Hafstad, Anne Dragøy; Clarke, K; Berge, Rolf; Larsen, Terje. 2008. TTA is a pan PPAR ligand which markedly stimulates fatty acid oxidation following in vivo administration. Cardiovascular Drugs and Therapy. 142-143.
  • Stunes, Astrid Kamilla; Gustafsson, Björn; Berge, Rolf Kristian; Westbroek, Irene; Reseland, Janne; Syversen, Unni. 2007. The PPAR gamma agonist pioglitazone exaggerates bone loss, while the PPAR alpha agonist fenofibrate maintains BMD and bone architecture in ovarectomized rats. Calcified Tissue International. S40-S40.
  • Erikstein, Bjarte Skoe; Tronstad, Karl Johan; McCormack, Emmet Martin; Schwede, Frank; Berge, Rolf Kristian; Gjertsen, Bjørn Tore. 2007. Synergistic anti-leukemic effect of protein kinase a activator and PPAR7agonist is independent of Bcl-2 status. Blood. 117B-117B.
  • Hafstad, Anne Dragøy; Khalid, Ahmed Murtaz; How, Ole-Jakob; Berge, Rolf; Larsen, Terje; Aasum, Ellen. 2007. In vivo administration of tetradecylthioacetic acid (TTA) in mice causes cardiac inefficiency and reduced post-ischemic ventricular function. Journal of Molecular and Cellular Cardiology.
  • Grimstad, Tore; Hausken, Trygve; Berge, Rolf Kristian; Aarsland, Torbjørn. 2007. Health effects from a regular intake of Atlantic salmon in patients with active ulcerative colitis. Scandinavian Journal of Gastroenterology. 26-26.
  • Aasum, Ellen; Khalid, Ahmed Murtaz; Gudbrandsen, OA; Larsen, Terje; Berge, Rolf. 2006. Indirect and direct effects of PPAR ligands on myocardial metabolism. Journal of Molecular and Cellular Cardiology. 931-932.
  • Ibrahim, Salah Osman; Haraldsen, Heidi Ellis; Miron, Talia; Dysvik, Bjarte; Berge, Rolf Kristian; Vasstrand, Endre N. 2005. Effects of the modified fatty acid tetradecylthioacetic acid (TTA) on an oral cancer progression model. Genomic and proteomic approaches. Oral Oncology. 164-165.
  • Iversen, PO; Sorensen, DR; Berge, Rolf Kristian; Rustan, AC; Drevon, CA. 2005. A sulfur-substituted fatty acid analog improves survival and impairs metastasis in rat models of acute leukemia. Experimental Hematology.
  • Berge, RK; Tronstad, KJ; Gudbrandsen, OA; Berge, K; Wergedahl, H; Grav, Hans J. 2004. Improved insulin sensitivity and reduced adipose tissue mass in relation to mitochondrial function, energy state and PPAR activation. Biochimica et Biophysica Acta - Bioenergetics. 203-203.
  • Dyrøy, Endre; Yndestad, A; Ueland, T; Aukrust, P; Berge, Rolf Kristian. 2004. Decreased TNF alpha induced endothelial activation in the presence of a new bioactive fatty acid. Chemistry and Physics of Lipids. 39-39.
  • Gudbrandsen, Oddrun Anita; Wergedahl, Hege; Berge, Rolf Kristian. 2004. Cholesterol lowering effect of bioactive proteins. Chemistry and Physics of Lipids. 74-74.
Vitenskapelig oversiktsartikkel/review
  • Dankel, Simon E Nitter; Staalesen, Vidar; Bjørndal, Bodil; Berge, Rolf Kristian; Mellgren, Gunnar; Burri, Lena. 2011. Tissue-specific effects of bariatric surgery including mitochondrial function. 435245.
  • Burri, Lena; Thoresen, G. Hege; Berge, Rolf Kristian. 2010. The Role of PPAR alpha Activation in Liver and Muscle. 11 sider.

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