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Simona Cheras bilde

Simona Chera

Førsteamanuensis, NCMM Young Associate Investigator
  • E-postSimona.Chera@uib.no
  • Telefon+47 55 97 12 62
  • Besøksadresse
    Jonas Lies vei 65
    Barnekliniken
    5021 Bergen
    Rom 
    3007
  • Postadresse
    Postboks 7804
    5020 Bergen
Utvalgte publikasjoner
  • Furuyama, Kenichiro; Chera, Simona; van Gurp, Leon; Oropeza, Daniel; Ghila, Luiza; Damond, Nicolas; Vethe, Heidrun; Paulo, Joao A.; Joosten, Antoinette M.; Berney, Thierry; Bosco, Domenico; Dorrell, Craig; Grompe, Markus; Ræder, Helge; Roep, Bart O.; Thorel, Fabrizio; Herrera, Pedro L. 2019. Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. Nature. 567: 43-48. doi: 10.1038/s41586-019-0942-8
  • Cigliola, Valentina; Ghila, Luiza; Thorel, Fabrizio; van Gurp, Leon; Baronnier, Delphine; Oropeza, Daniel; Gupta, Simone; Miyatsuka, Takeshi; Kaneto, Hideaki; Magnuson, Mark A; Osipovich, Anna B; Sander, Maike; Wright, Christopher EV; Thomas, Melissa K; Furuyama, Kenichiro; Chera, Simona; Herrera, Pedro L. 2018. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells. Nature Cell Biology. 20: 1267-1277. doi: 10.1038/s41556-018-0216-y
  • Chera, Simona; Herrera, Pedro L. 2016. Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion. Current Opinion in Genetics and Development. 40: 1-10. doi: 10.1016/j.gde.2016.05.010
Tidsskriftartikler
  • Furuyama, Kenichiro; Chera, Simona; van Gurp, Leon; Oropeza, Daniel; Ghila, Luiza; Damond, Nicolas; Vethe, Heidrun; Paulo, Joao A.; Joosten, Antoinette M.; Berney, Thierry; Bosco, Domenico; Dorrell, Craig; Grompe, Markus; Ræder, Helge; Roep, Bart O.; Thorel, Fabrizio; Herrera, Pedro L. 2019. Diabetes relief in mice by glucose-sensing insulin-secreting human α-cells. Nature. 567: 43-48. doi: 10.1038/s41586-019-0942-8
  • Vethe, Heidrun; Ghila, Luiza; Berle, Magnus; Hoareau, Laurence; Haaland, Øystein Ariansen; Scholz, Hanne; Paulo, Joao A.; Chera, Simona; Ræder, Helge. 2019. The effect of WnT pathway modulators on human iPSC-derived pancreatic beta cell maturation. Frontiers in Endocrinology. 10. doi: 10.3389/fendo.2019.00293
  • Vethe, Heidrun; Ghila, Luiza; Berle, Magnus; Hoareau, Laurence; Haaland, Øystein Ariansen; Scholz, Hanne; Paulo, Joao A.; Chera, Simona; Ræder, Helge. 2019. Modulating Wnt signaling in human induced pluripotent stem cell-derived S7 cells. Frontiers in Endocrinology. Publisert 2019-05-08. doi: 10.3389/fendo.2019.00293
  • Berle, Magnus; Ghila, Luiza; Vethe, Heidrun; Chaudhry, Beenish Adeel; Garberg, Hilde Kristin; Beisland, Christian; Haaland, Øystein Ariansen; Oveland, Eystein; Halvorsen, Ole Johan; Davidsson, Thomas; Chera, Simona. 2018. Novel protein signatures suggest progression to muscular invasiveness in bladder cancer. PLOS ONE. 13:e0206475: 1-15. doi: 10.1371/journal.pone.0206475
  • Cigliola, Valentina; Ghila, Luiza; Thorel, Fabrizio; van Gurp, Leon; Baronnier, Delphine; Oropeza, Daniel; Gupta, Simone; Miyatsuka, Takeshi; Kaneto, Hideaki; Magnuson, Mark A; Osipovich, Anna B; Sander, Maike; Wright, Christopher EV; Thomas, Melissa K; Furuyama, Kenichiro; Chera, Simona; Herrera, Pedro L. 2018. Pancreatic islet-autonomous insulin and smoothened-mediated signalling modulate identity changes of glucagon+ α-cells. Nature Cell Biology. 20: 1267-1277. doi: 10.1038/s41556-018-0216-y
  • Chakravarthy, Harini; Gu, Xueying; Enge, Martin; Dai, Xiaoqing; Wang, Yong; Damond, Nicolas; Downie, Carolina; Liu, Kathy; Wang, Jing; Xing, Yuan; Chera, Simona; Thorel, Fabrizio; Quake, Stephen; Oberholzer, Jose; MacDonald, Patrick E.; Herrera, Pedro L.; Kim, Seung K. 2017. Converting adult pancreatic islet α cells into β cells by targeting both Dnmt1 and Arx. Cell Metabolism. 25: 622-634. doi: 10.1016/j.cmet.2017.01.009
  • Vethne, Heidrun; Bjørlykke, Yngvild; Ghila, Luiza; Paulo, Joao A.; Scholz, Hanne; Gygi, Steven P.; Chera, Simona; Ræder, Helge. 2017. Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells. Scientific Reports. 7:4780: 1-14. doi: 10.1038/s41598-017-04979-w
  • Chera, Simona; Herrera, Pedro L. 2016. Regeneration of pancreatic insulin-producing cells by in situ adaptive cell conversion. Current Opinion in Genetics and Development. 40: 1-10. doi: 10.1016/j.gde.2016.05.010
  • Cigliola, Valentina; Thorel, Fabrizio; Chera, Simona; Herrera, Pedro L. 2016. Stress-induced adaptive islet cell identity changes. Diabetes, obesity and metabolism. 18: 87-96. doi: 10.1111/dom.12726

Se fullstendig oversikt over publikasjoner i CRIStin.

  1. Vethe H, Ghila L, Hoareau L, Bjørlykke Y, Berle M, Haaland ØA, Hoareau L, Paulo J, Scholz H, Chera S, Ræder H. “Modulating Wnt signaling in human induced pluripotent stem cell-derived S7 cells” – Front. Endocrinol., 2019, 08 May doi: 10.3389/fendo.2019.00293
  2. Furuyama K, Chera S, van Gurp L, Damond N, Oropeza D, Ghila L, Vethe H, Paulo JA, Joosten AM, Berney T, Bosco D, Dorrel C, Grompe M, Ræder H, Roep BO, Thorel F and Herrera PL, Diabetes relief in mice by glucose-sensing insulin-secreting human a-cells, Nature 2019 567: 43–48
  3. Cigliola V, Ghila L, Thorel F, van Gurp L, Baronnier D, Gupta S, Miyatsuka T, Kaneto H, Magnuson MA, Osipovich AB, Sander M, Wright C, Thomas MK, Furuyama K, Chera S and Herrera PL, Pancreatic Islet-Autonomous Signals Modulate Identity Changes of Glucagon+ α-Cells, Nature Cell Biology 2018 Nov;20(11):1267-1277. doi: 10.1038/s41556-018-0216-y. PMID: 30361701
  4. Berle M, Ghila L, Vethe H, Chaudhry A, Garberg H, Beisland C, Haaland ØA, Oveland E, Halvorsen OJ, Davidsson T, Chera S. Novel protein signatures suggest progression to muscular invasiveness in bladder cancer. PLoS One 2018 Nov 12;13(11):e0206475. doi: 10.1371/journal.pone.0206475. PMID: 30419021
  5. Vethe H, Bjørlykke Y, Ghila LM, Paulo JA, Scholz H, Gygi SP, Chera S, Ræder H. Probing the missing mature β-cell proteomic landscape in differentiating patient iPSC-derived cells. Scientific Reports. 2017 Jul 6;7(1):4780. doi: 10.1038/s41598-017-04979-w. PMID: 28684784 Cellular and Molecular Mechanisms of Regeneration in Pancreas
  6. Chakravarthy H, Gu X, Enge M, Dai X, Wang Y, Damond N, Downie C, Liu K, Wang J, Xing Y, Chera S, Thorel F, Quake S, Oberholzer J, MacDonald PE, Herrera PL, Kim SK. Converting Adult Pancreatic Islet α Cells into β Cells by Targeting Both Dnmt1 and Arx, 2017 Cell Metabolism 25(3):622-634.
  7. Cigliola V, Thorel F, Chera S, Herrera PL. Stress-induced adaptive islet cell identity changes 2016 Diabetes Obes Metab. 2016 Sep;18 Suppl 1:87-96. doi: 10.1111/dom.12726.
  8. Chera S, Herrera PL. Regeneration of Pancreatic Insulin-Producing Cells by In Situ Adaptive Cell Conversion, 2016 Current Opinion in Genetics and Development 40:1-10, 10.1016/j.gde.2016.05.010
  9. Chera S, Baronnier-Caffé D, Ghila L, Cigliola V, Jensen JN, Gu G, Furuyama K, Thorel F, Gribble FM, Reimann F, Herrera PL. Diabetes recovery by age-dependent conversion of pancreatic δ- or α-cells into insulin producers 2014 Nature 514(7523):503-507 [Comment in Nat Rev Endocrinol. 2014: Diabetes: reprogrammed pancreatic δ-cells restore insulin production].