Hjem
Stig Harthugs bilde

Stig Harthug

Professor
  • E-postStig.Harthug@uib.no
  • Telefon+47 55 97 53 80+47 957 52 191
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen

Syehusinfeksjoner og spredning av antibiotikaresistente bakterier er en pasientsikkerhetstrussel. Vi forsker for å forstå hvordan vi kan møte disse utfordringene gjennom overvåking og effektive forebyggingsstrategier. Implementering av pasientsikkerhetstiltak som sjekklister og retningslinjer er viktige tilnærminger.

Vitenskapelig artikkel
  • Vis forfatter(e) (2022). Development and validation of patients' surgical safety checklist. BMC Health Services Research. 12 sider.
  • Vis forfatter(e) (2022). Antibiotic use in children before, during and after hospitalisation. Pharmacoepidemiology and Drug Safety. 749-757.
  • Vis forfatter(e) (2021). Prevalence of patients “at risk of malnutrition” and nutritional routines among surgical and non-surgical patients at a large university hospital during the years 2008–2018. Clinical Nutrition. 4738-4744.
  • Vis forfatter(e) (2021). Nationwide audit and feedback on implementation of antibiotic stewardship programmes in Norwegian hospitals. JAC-Antimicrobial Resistance (JAC-AMR). 1-6.
  • Vis forfatter(e) (2020). Patients’ and healthcare workers’ recommendations for a surgical patient safety checklist – a qualitative study. BMC Health Services Research. 1-10.
  • Vis forfatter(e) (2020). Impact of the Norwegian National Patient Safety Program on implementation of the WHO Surgical Safety Checklist and on perioperative safety culture. BMJ Open Quality. 1-9.
  • Vis forfatter(e) (2020). Identifying targets for antibiotic stewardship interventions through analysis of the antibiotic prescribing process in hospitals - a multicentre observational cohort study. Antimicrobial Resistance and Infection Control. 11 sider.
  • Vis forfatter(e) (2020). How does the WHO Surgical Safety Checklist fit with existing perioperative risk management strategies? An ethnographic study across surgical specialties. BMC Health Services Research. 1-11.
  • Vis forfatter(e) (2020). Epidemiology and Antimicrobial Susceptibility of Invasive Bacterial Infections in Children—A Population-Based Study From Norway. The Pediatric Infectious Disease Journal. 403-410.
  • Vis forfatter(e) (2020). Effects of external inspections on sepsis detection and treatment: a stepped-wedge study with cluster-level randomisation. BMJ Open. 10 sider.
  • Vis forfatter(e) (2020). Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study. PLOS ONE. 1-15.
  • Vis forfatter(e) (2020). A health economic evaluation of the World Health Organization Surgical Safety Checklist. Annals of Surgery. 1-6.
  • Vis forfatter(e) (2019). Weight loss and BMI criteria in GLIM's definition of malnutrition is associated with postoperative complications following abdominal resections – Results from a National Quality Registry. Clinical Nutrition. 1-7.
  • Vis forfatter(e) (2019). Use of microbiology tests in the era of increasing AMR rates- a multicentre hospital cohort study. Antimicrobial Resistance and Infection Control. 1-8.
  • Vis forfatter(e) (2019). The association between adherence to national antibiotic guidelines and mortality, readmission and length of stay in hospital inpatients: results from a Norwegian multicentre, observational cohort study. Antimicrobial Resistance and Infection Control. 10 sider.
  • Vis forfatter(e) (2019). Measuring discharge quality based on elderly patients’ experiences with discharge conversation: a cross-sectional study. BMJ Open Quality.
  • Vis forfatter(e) (2019). Investigation of perioperative work processes in provision of antibiotic prophylaxis: a prospective descriptive qualitative study across surgical specialties in Norway . BMJ Open. 1-11.
  • Vis forfatter(e) (2019). Discharge care quality in hospitalised elderly patients: Extended validation of the Discharge Care Experiences Survey. PLOS ONE. 1-15.
  • Vis forfatter(e) (2019). Causal analysis of World Health Organization's surgical safety checklist implementation quality and impact on care processes and patient outcomes: Secondary analysis from a large stepped wedge cluster randomized controlled trial in Norway. Annals of Surgery. 283-290.
  • Vis forfatter(e) (2018). The effect of antibiotic stewardship interventions with stakeholder involvement in hospital settings: A multicentre, cluster randomized controlled intervention study. Antimicrobial Resistance and Infection Control. 12 sider.
  • Vis forfatter(e) (2018). Elderly patients’ (≥65 years) experiences associated with discharge; Development, validity and reliability of the Discharge Care Experiences Survey. PLOS ONE. 1-17.
  • Vis forfatter(e) (2018). A positive association between nutritional risk and the incidence of surgical site infections: A hospital-based register study. PLOS ONE. 1-10.
  • Vis forfatter(e) (2017). Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in Mid-Norway: A prospective observational study. BMC Infectious Diseases. 1-11.
  • Vis forfatter(e) (2017). Effects of external inspection on sepsis detection and treatment: a study protocol for a quasiexperimental study with a stepped-wedge design. BMJ Open. 1-16.
  • Vis forfatter(e) (2017). Causal Analysis of World Health Organization's Surgical Safety Checklist Implementation Quality and Impact on Care Processes and Patient Outcomes: Secondary Analysis From a Large Stepped Wedge Cluster Randomized Controlled Trial in Norway. Annals of Surgery.
  • Vis forfatter(e) (2017). Burden of bloodstream infection in an area of Mid-Norway 2002-2013: A prospective population-based observational study. BMC Infectious Diseases. 1-14.
  • Vis forfatter(e) (2017). Adverse events and in-hospital mortality: An analysis of all deaths in a Norwegian health trust during 2011. BMC Health Services Research. 1-7.
  • Vis forfatter(e) (2015). Need for more targeted measures - Only less severe hospital-associated infections declined after introduction of an infection control program. Journal of Infection and Public Health. 282-290.
  • Vis forfatter(e) (2015). Mortality related to hospital-associated infections in a tertiary hospital; repeated cross-sectional studies between 2004-2011. Antimicrobial Resistance and Infection Control. 1-8.
  • Vis forfatter(e) (2015). Effect of the World Health Organization Checklist on Patient Outcomes: A Stepped Wedge Cluster Randomized Controlled Trial. Annals of Surgery. 821-828.
  • Vis forfatter(e) (2014). Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection: a prospective observational study. European Journal of Clinical Microbiology and Infectious Diseases. 609-617.
  • Vis forfatter(e) (2013). Investigating the use of patient involvement and patient experience in quality improvement in Norway: rhetoric or reality? BMC Health Services Research.
  • Vis forfatter(e) (2013). Impact of the World Health Organization's Surgical Safety Checklist on safety culture in the operating theatre: a controlled intervention study. British Journal of Anaesthesia. 807-815.
  • Vis forfatter(e) (2012). Factors influencing the development of evidence-based practice among nurses: a self-report survey. BMC Health Services Research.
  • Vis forfatter(e) (2010). Patient safety in surgical environments: Cross-countries comparison of psychometric properties and results of the Norwegian version of the Hospital Survey on Patient Safety. BMC Health Services Research. 10 sider.
  • Vis forfatter(e) (2009). Severe consequences of healthcare-associated infections among residents of nursing homes: A cohort study. Journal of Hospital Infection. 269-274.
  • Vis forfatter(e) (2009). Association between use of hand hygiene products and rates of health care-associated infections in a large university hospital in Norway. American Journal of Infection Control. 311-317.
  • Vis forfatter(e) (2007). Healthcare-associated infection among residents of long-term care facilities: a cohort and nested case-control study. Journal of Hospital Infection. 334-340.
  • Vis forfatter(e) (2007). Antimicrobial resistance predicts death in Tanzanian children with bloodstream infections: a prospective cohort study. BMC Infectious Diseases.
  • Vis forfatter(e) (2005). Extended spectrum beta-lactamases among Gram-negative bacteria of nosocomial origin from an Intensive Care Unit of a tertiary health facility in Tanzania. BMC Infectious Diseases. 86.
  • Vis forfatter(e) (2005). A multi-centre prospective study of febrile neutropenia in Norway: microbiological findings and antimicrobial susceptibility. APMIS - Journal of Pathologiy, Microbiology and Immunology. 455-464.
  • Vis forfatter(e) (2004). Surveillance of antimicrobial resistance at a tertiary hospital in Tanzania. BMC Public Health. 45.
  • Vis forfatter(e) (2004). Role of penicillin-binding protein 5 C-terminal amino acid substitutions in conferring ampicillin resistance in Norwegian clinical strains of Enterococcus faecium. APMIS - Journal of Pathologiy, Microbiology and Immunology. 291-298.
  • Vis forfatter(e) (2004). Duplex real-time PCR assay for rapid detection of ampicillin-resistant Enterococcus faecium. Antimicrobial Agents and Chemotherapy. 556-560.
  • Vis forfatter(e) (2004). Comparative analysis of amplified fragment length polymorphism and pulsed field gel electrophoresis in a hospital outbreak and subsequent endemicity of ampicillin-resistant Enterococcus faecium. FEMS Immunology and Medical Microbiology. 33-39.
  • Vis forfatter(e) (2003). Prevalence of resistance to ampicillin, gentamicin and vancomycin in Enterococcus faecalis and Enterococcus faecium isolates from clinical specimens and use of antimicrobials in five Nordic hospitals. Journal of Antimicrobial Chemotherapy.
  • Vis forfatter(e) (2003). Outbreak of infection with high-level gentamicin-resistant Enterococcus faecalis (HLGRE) in a Norwegian hospital. Clinical Microbiology and Infection (CMI). 662-669.
  • Vis forfatter(e) (2003). Molecular characterization of ampicillin-resistant Enterococcus faecium isolates from hospitalized patients in Norway. Journal of Clinical Microbiology. 2330-2336.
  • Vis forfatter(e) (2002). The prevalence of faecal carriage of ampicillin-resistant and high- level gentamicin-resistant enterococci among inpatients at 10 major Norwegian hospitals. Journal of Hospital Infection. 145-154.
  • Vis forfatter(e) (2001). Infeksjonsutbrudd med meticillinresistente gule stafylokokker ved Haukeland Sykehus. Tidsskrift for Den norske legeforening. 204-208.
  • Vis forfatter(e) (2000). Vancomycin resistance in a clonal outbreak caused by ampicillin-resistant Enterococcus faecium. European Journal of Clinical Microbiology and Infectious Diseases. 19-28.
  • Vis forfatter(e) (2000). Utbrudd av infeksjon med multiresistent Acinetobacter baumannii. Tidsskrift for Den norske legeforening. 1028-1033.
  • Vis forfatter(e) (2000). Outbreak of multiresistant Enterococcus faecium in a Norwegian university hospital - risk factors for faecal colonisation. APMIS - Journal of Pathologiy, Microbiology and Immunology. 296-302.
  • Vis forfatter(e) (2000). Outbreak of ampicillin-resistant Enterococcus faecium--risk factors for faecal colonisation. APMIS - Journal of Pathologiy, Microbiology and Immunology. 296-302.
  • Vis forfatter(e) (2000). Nosocomial outbreak of ampicillin resistant Enterococcus faecium: Risk factors for infection and fatal outcome. Journal of Hospital Infection. 135-144.
  • Vis forfatter(e) (2000). Nosocomial outbreak of ampicillin resistant Enterococcus faecium: Risk factors for infection and fatal outcome. Journal of Hospital Infection. 135-144.
  • Vis forfatter(e) (2000). Nosocomial outbreak of ampicillin resistant Enterococcus faecium. Risk factors for infection and fatal outcome. Ethiopian Journal of Health Development. 135-144.
  • Vis forfatter(e) (2000). Emergence of vancomycinresistant E. faecium in a clonal hospital outbreak of multiresistant E. faecium. Clinical Microbiology and Infection (CMI). 19-28.
  • Vis forfatter(e) (1999). Treatment with interferon-alpha2a alone or interferon-alpha2a plus ribavirin in patients with chronic hepatitis C previously treated with interferon-alpha2a. Scandinavian Journal of Gastroenterology. 194-198.
  • Vis forfatter(e) (1998). The effect of treatment with alpha-interferon on hepatitis G/GBV-C viraemia. The Construct Group. Scandinavian Journal of Gastroenterology. 195-200.
  • Vis forfatter(e) (1998). Infeksjoner forårsaket av multiresistente enterokokker i Norge. Tidsskrift for Den norske legeforening. 4070-4073.
  • Vis forfatter(e) (1997). Genotype, viral load and age as independent predictors of treatment outcome of interferon-alpha 2 a treatment in patients with chronic hepatitis C. Construct group. Scandinavian Journal of Infectious Diseases. 17-22.
  • Vis forfatter(e) (1997). Genotype, viral load and age as independent predictors of treatment outcome of interferon-alpha 2 a treatment in patients with chronic hepatitis C. Construct group. Scandinavian Journal of Infectious Diseases. 17-22.
  • Vis forfatter(e) (1994). Bloodstream infections at a Norwegian university hospital, 1974-1979 and 1988-1989: changing etiology, clinical features, and outcome. Clinical Infectious Diseases. 246-256.
  • Vis forfatter(e) (1994). Bloodstream infections at a Norwegian University hospital 1974-1979 and 1988-1989: Changing Etiology, Clinical features and outcome. Clinical Infectious Diseases. 246-256.
  • Vis forfatter(e) (1994). Behandling av infeksjoner med koagulase-negative stafylokokker netilmicin. Netilyn - håndbok. 35-39.
  • Vis forfatter(e) (1994). Antibiotikaprofylakse og forekomst av sårinfeksjoner ved hjerte og karkirurgi. Tidsskrift for Den norske legeforening. 3071-3074.
  • Vis forfatter(e) (1994). Antibiotic prophylaxis and post-operative wound infection rates in cardiovascular surgery. Tidsskrift for Den norske legeforening. 3071-3074.
  • Vis forfatter(e) (1994). A longitudinal study of phagocyte function in HIV-infected patients. AIDS (London). 771-777.
  • Vis forfatter(e) (1994). A longitudinal study of phagocyte function in HIV infected patients. AIDS (London). 771-777.
  • Vis forfatter(e) (1993). Prevalence of antibodies to hepatitis C virus and association with intravenous drug abuse and tattooing in a national prison in Norway. European Journal of Clinical Microbiology and Infectious Diseases. 673-676.
  • Vis forfatter(e) (1993). Prevalence of Antibodies of Hepatitis C Virus and Association with Intravenous Drug Abuse and Tattooing in a National Prison in Norway. European Journal of Clinical Microbiology and Infectious Diseases. 673-676.
  • Vis forfatter(e) (1993). Hørselstap etter erytromycinbehandling. Tidsskrift for Den norske legeforening. 2810-2811.
  • Vis forfatter(e) (1993). Hørselstap etter erytromycinbehandling. Tidsskrift for Den norske legeforening. 2810-2811.
Rapport
  • Vis forfatter(e) (1991). Mikrobiologi, infeksjoner, hygiene. Kompendium for studenter ved Bergen vernepleierhøgskole. .
Faglig foredrag
  • Vis forfatter(e) (2014). Prior statin use and 90-day mortality in Gram-negative and Gram-positive bloodstream infection.
Vitenskapelig foredrag
  • Vis forfatter(e) (2021). Surgical patients' safety checklist (PASC) - a feasibility study of surgical checklists in a stepped wedge cluster randomized controlled trial.
  • Vis forfatter(e) (2019). Explanations On Improved Patient Outcomes- And Perioperative Care Processes, Following Implementation Of The World Health Organization’s Surgical Safety Checklist .
  • Vis forfatter(e) (2018). Use of WHO Surgical Safety Checklist Improved Work Processes in Operating Theatre and Patient Outcome – a Stepped Wedge Cluster RCT.
  • Vis forfatter(e) (2018). Experiences on utilization of a stepped wedge cluster randomized controlled trial designed implementation of surgical safety checklists in two Norwegian hospitals. .
  • Vis forfatter(e) (2016). EFFICACY OF A SURGICAL SAFETY CHECKLIST IN IMPROVING ANTIBIOTIC PROPHYLAXIS IN SURGERY.
  • Vis forfatter(e) (2005). Epidemiological analysis of MRSA in two counties in Western Norway.
  • Vis forfatter(e) (2002). Tiltak mot MRSA.
  • Vis forfatter(e) (2002). Sykehusinfeksjoner, sykehushygiene.
  • Vis forfatter(e) (2002). Resistente bakterier som sykehusproblem.
  • Vis forfatter(e) (2002). Registrering av postoperative sårinfeksjoner.
  • Vis forfatter(e) (2002). Methicillinresistant Staphylococcus aureus in Norway - epidemiology, surveillance and precautions.
  • Vis forfatter(e) (2002). Innledning om sykehusinfeksjoner.
  • Vis forfatter(e) (2002). Infeksjonsepidemiologiske metoder.
  • Vis forfatter(e) (2002). Clinical impact of enterococcal infections.
  • Vis forfatter(e) (2002). Case multiresistente -enterokokker.
  • Vis forfatter(e) (2002). Antibiotikaprofylakse.
  • Vis forfatter(e) (2001). Praktisk antbiotikabruk.
  • Vis forfatter(e) (1998). Outbreak of multiresistant enterococcus faecium in a Norwegian university hospital - riskfactors for infection.
  • Vis forfatter(e) (1998). Outbreak of multiresistant enterococcus faecium in a Norwegian university hospital - riskfactors for faecal colonization.
  • Vis forfatter(e) (1997). J-34. Vancomycin resistance emerging in a clonal outbreak caused by multiresistant Enterococcus faecium.
Leder
  • Vis forfatter(e) (2002). Infeksjoner og bruk av antibiotika i sykehjem. Tidsskrift for Den norske legeforening. 2349-2349.
Leserinnlegg
  • Vis forfatter(e) (2019). It’s not miraculous, it’s a no-brainer. The BMJ.
  • Vis forfatter(e) (2002). Smitteverntiltak i sykehus. Tidsskrift for Den norske legeforening. 2317-2318.
  • Vis forfatter(e) (2002). Antibiotikaresistenta bakterier - ett hot även för Norden? Sjukhusfarmaci. 46-51.
Short communication
  • Vis forfatter(e) (2001). Mikrobiell resistens. Tidsskrift for Den norske legeforening. 3413.
Anmeldelse
  • Vis forfatter(e) (2002). Bra om morsmelkbanker. Tidsskrift for Den norske legeforening. 1511-1511.
Fagbok
  • Vis forfatter(e) (2001). Kvalitetskontroll (KK) av resistensbestemmelser for aerobe, hurtigvoksende bakterier med agardiffusjon. Arbeidsgruppen for antibiotikaspørsmål.
  • Vis forfatter(e) (2001). Bruk av antibiotika i sykehus. Statens helsetilsyn.
  • Vis forfatter(e) (1996). Stafylokokkinfeksjoner. Eli Lilly Norge, Oslo.
  • Vis forfatter(e) (1996). Stafylokokkinfeksjoner. Eli Lilly Norge AS, Oslo.
  • Vis forfatter(e) (1996). Antibiotikafølsomhet for stafylokokker. Eli Lilly Norge AS.
  • Vis forfatter(e) (1995). Antibiotika-assosiert diarre. Oslo: Upjohn Information.
Populærvitenskapelig artikkel
  • Vis forfatter(e) (1999). Utbrudd med multiresistente Acinetobacter baumannii ved en brannskadeavdeling. SHE-nytt. 1.
Kronikk
  • Vis forfatter(e) (1998). Utbrudd med multiresistente Acinetobacter baumanii ved Brannskadeavsnittet, Haukeland sykehus. MSIS-rapport.
Brev til redaktøren
  • Vis forfatter(e) (2016). Reply. Annals of Surgery. e24-e25.
  • Vis forfatter(e) (2014). Reply to "Letter to Editor Concerning the Article-Effect of the World Health Organization Checklist on Patient Outcomes: A Stepped Wedge Cluster Randomized Controlled Trial". Annals of Surgery. 1-1.
Doktorgradsavhandling
  • Vis forfatter(e) (2016). Lessons learned from infection surveillance: Occurrence, risk factors and consequences of healthcare-associated infections in hospitals and long-term care facilities.
  • Vis forfatter(e) (2007). Antimicrobial resistance in bacterial infections in urban and rural Tanzania.
  • Vis forfatter(e) (2005). Ampicillin resistance in Enterococcus faecium.
  • Vis forfatter(e) (2001). Resistance to antimicrobial agents with special emphasis on bacteremia and nosocomial infection. ..
Vitenskapelig Kapittel/Artikkel/Konferanseartikkel
  • Vis forfatter(e) (2012). Organizing for quality and safety in health care - the Norwegian Case. 7 sider.
  • Vis forfatter(e) (2011). Measuring quality and safety in Norwegian health care - time for a change? 5 sider.
  • Vis forfatter(e) (2000). Evaluering av undervisning og læring i etterutdanning av leger. 12 sider.
  • Vis forfatter(e) (1996). Antimikrobiell behandling av stafylokokkinfeksjoner. 12 sider.
  • Vis forfatter(e) (1992). Septicaemia at a Norwegian University Hospital 1974-79 (5 years) and 1988-89 (2 years). A comparative study. 2 sider.
Poster
  • Vis forfatter(e) (2013). Sustainable quality improvement as a result of interactions on micro-meso-macro levels.
  • Vis forfatter(e) (2011). Patient safety in surgical environments: Cross-countries comparison of psychometric properties and results of the Norwegian version of the Hospital Survey on Patient Safety.
  • Vis forfatter(e) (2005). Epidemiological analysis of MRSA in two counties in western Norway.
  • Vis forfatter(e) (2001). Antibiotic resistance among enterococci in Nordic countries: analysis of isolates from five clinical microbiological laboratories.
  • Vis forfatter(e) (2001). A Multi-Center Prospective Study of 274 Episodes of Febrile Neutropenia in Norway.
  • Vis forfatter(e) (2000). Outbreak of infections caused by high-level gentamicin-resistant (mic > 512 mg/l) Enterococcus faecalis (HLGRE) in Haukeland university hospital, Norway.
  • Vis forfatter(e) (2000). No VRE-carriers and low prevalence of ARE and HLAR among in-patients in 10 major Norwegian hospitals.
Errata
  • Vis forfatter(e) (2021). Correction: Early diagnosis of sepsis in emergency departments, time to treatment, and association with mortality: An observational study. PLOS ONE.
  • Vis forfatter(e) (2017). Erratum to: Trends in antimicrobial resistance and empiric antibiotic therapy of bloodstream infections at a general hospital in mid-Norway: A prospective observational study. BMC Infectious Diseases.
Nettsider (opplysningsmateriale)
  • Vis forfatter(e) (2021). Protocol: Context influences on implementation of three patient safety practices – a scoping review.

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