Hjem
Tehmina Mustafas bilde

Tehmina Mustafa

Professor, Senter for internasjonal helse
  • E-postTehmina.Mustafa@uib.no
  • Telefon+47 55 58 67 22
  • Besøksadresse
    Overlege Danielsens hus, Årstadveien 21
    Rom 
    525
  • Postadresse
    Postboks 7804
    5020 Bergen

Tehmina Mustafa has research experience on various aspects of tuberculosis, including clinical and basic laboratory research on immunepathogenesis and diagnosis of disease. Her main interest is in the development of better diagnostic methods for tuberculosis. She has been busy building research and academic partnerships with multiple institutions in Tanzania, Zanzibar, India and Pakistan, and is currently leading a multicenter international project in four countries on the implementation of a better diagnostic test for tuberculosis in the routine clinical settings.

Tidsskriftartikler
  • Jørstad, Melissa Davidsen; Assmus, Jörg; Marijani, Msafiri; Sviland, Lisbeth; Mustafa, Tehmina. 2018. Diagnostic delay in extrapulmonary tuberculosis and impact on patient morbidity: A study from Zanzibar. PLoS ONE. 13:e0203593: 1-17. doi: 10.1371/journal.pone.0203593
  • Jørstad, Melissa Davidsen; Marijani, Msafiri; Dyrhol-Riise, Anne Ma; Sviland, Lisbeth; Mustafa, Tehmina. 2018. MPT64 antigen detection test improves routine diagnosis of extrapulmonary tuberculosis in a low-resource setting: A study from the tertiary care hospital in Zanzibar. PLoS ONE. 13:e0196723: 1-15. doi: 10.1371/journal.pone.0196723
  • Mustafa, Tehmina; Shahzad, Yasir; Kiani, Ayyaz. 2018. A survey of knowledge, attitude, and practices of private retail pharmacies staff in tuberculosis care: Study from Dera Ismail Khan City, Pakistan. Journal of Pharmaceutical Policy and Practice. 11:7: 1-7. doi: 10.1186/s40545-018-0134-1
  • Purohit, Manju; Sviland, Lisbeth; Wiker, Harald G; Mustafa, Tehmina. 2017. Rapid and specific diagnosis of extrapulmonary tuberculosis by immunostaining of tissues and aspirates with anti-MPT64. Applied immunohistochemistry & molecular morphology (Print). 25: 282-288. doi: 10.1097/PAI.0000000000000300
  • Mustafa, Tehmina; Brokstad, Karl Albert; Mfinanga, Sayoki Godfrey M.; Wiker, Harald G. 2015. Multiplex Analysis of Pro- or Anti-Inflammatory Serum Cytokines and Chemokines in relation to Gender and Age among Tanzanian Tuberculous Lymphadenitis Patients. Tuberculosis research and treatment.
  • Purohit, Manju; Mustafa, Tehmina. 2015. Laboratory Diagnosis of Extra-pulmonary Tuberculosis (EPTB) in Resource-constrained Setting: State of the Art, Challenges and the Need. Journal of Clinical and Diagnostic Research.
  • Mustafa, Tehmina; Leversen, Nils Anders; Sviland, Lisbet; Wiker, Harald G. 2014. Differential in vivo expression of mycobacterial antigens in Mycobacterium tuberculosis infected lungs and lymph node tissues. BMC Infectious Diseases. 14:535. doi: 10.1186/1471-2334-14-535
  • Tadele, Agerie; Beyene, Demissew Balcha; Hussein, Jemal; Gemechu, Tuffa; Birhanu, Asaye; Mustafa, Tehmina; Tsegaye, Aster; Aseffa, Abraham; Sviland, Lisbeth. 2014. Immunocytochemical detection of Mycobacterium Tuberculosis complex specific antigen, MPT64, improves diagnosis of tuberculous lymphadenitis and tuberculous pleuritis. BMC Infectious Diseases. 14. doi: 10.1186/s12879-014-0585-1
  • Leversen, Nils Anders; Sviland, Lisbeth; Wiker, Harald G; Mustafa, Tehmina. 2012. Long-term persistence of BCG Pasteur in lungs of C57BL/6 mice following intranasal infection. Scandinavian Journal of Immunology. 75: 489-499. doi: 10.1111/j.1365-3083.2012.02683.x
  • Purohit, Manju; Mustafa, Tehmina; Wiker, Harald G; Sviland, Lisbet. 2012. Rapid diagnosis of tuberculosis in aspirate, effusions, and cerebrospinal fluid by immunocytochemical detection of Mycobacterium tuberculosis complex specific antigen MPT64. Diagnostic Cytopathology. 40: 782-791. doi: 10.1002/dc.21637
  • Leversen, Nils Anders; Mustafa, Tehmina; Wiker, Harald G. 2010. Comparison of Immune Response in Mice Infected with M-Bovis BCG Russia and M-Bovis BCG Pasteur. Scandinavian Journal of Immunology. 71: 536-536.
  • Wiker, Harald G; Mustafa, Tehmina; Bjune, Gunnar; Harboe, Morten. 2010. Evidence for waning of latency in a cohort study of tuberculosis. BMC Infectious Diseases. 10. doi: 10.1186/1471-2334-10-37
  • Purohit, Manju; Mustafa, Tehmina; Mørkve, Odd; Sviland, Lisbet. 2009. Gender differences in the clinical diagnosis of tuberculous lymphadenitis-a hospital-based study from Central India. International Journal of Infectious Diseases. 13: 600-605. doi: 10.1016/j.ijid.2008.06.046
  • Baba, Kamaldeen; Dyrhol-Riise, Anne Ma; Sviland, Lisbet; Langeland, Nina; Hoosen, Anwar A.; Wiker, Harald G; Mustafa, Tehmina. 2008. Rapid and Specific Diagnosis of Tuberculous Pleuritis With Immunohistochemistry by Detecting Mycobacterium tuberculosis Complex Specific Antigen MPT64 in Patients From a HIV Endemic Area. Applied immunohistochemistry & molecular morphology (Print). 16: 554-561. doi: 10.1097/PAI.0b013e31816c3f79
  • Baba, Kamaldeen; Pathak, Sharad; Sviland, Lisbet; Langeland, Nina; Hoosen, Anwar A.; Åsjø, Birgitta; Dyrhol-Riise, Anne Ma; Mustafa, Tehmina. 2008. Real-time quantitative PCR in the diagnosis of tuberculosis in formalin-fixed paraffin-embedded pleural tissue in patients from a high HIV endemic area. Diagnostic molecular pathology. 17: 112-117.
  • Mustafa, Tehmina. 2008. Does leptin have a role in immunity to tuberculosis? Indian Journal of Medical Research (IJMR). 128: 691-693.
  • Mustafa, Tehmina; Wiker, Harald G; Mørkve, Odd; Sviland, Lisbet. 2008. Differential expression of mycobacterial antigen MPT64, apoptosis and inflammatory markers in multinucleated giant cells and epithelioid cells in granulomas caused by Mycobacterium tuberculosis. Virchows Archiv. 452: 449-456. doi: 10.1007/s00428-008-0575-z
  • Purohit, Manju; Mustafa, Tehmina; Sviland, Lisbet. 2008. Detection of Mycobacterium tuberculosis by polymerase chain reaction with DNA eluted from aspirate smears of tuberculous lymphadenitis. Diagnostic molecular pathology. 17: 174-178. doi: 10.1097/PDM.0b013e31815c1195
  • Qureshi, Samera Azeem; Mørkve, Odd; Mustafa, Tehmina. 2008. Patient and health systems delays: Health-care seeking behaviour among pulmonary tuberculosis patients in Pakistan. JOURNAL OF PAKISTAN MEDICAL ASSOCIATION. 58: 318-321.
  • Mfinanga, Sayoki Godfrey M.; Sviland, Lisbet; Chande, H; Mustafa, Tehmina; Mørkve, Odd. 2007. How does clinical diagnosis of mycobacterial adenitis correlate with histological findings? East African Journal of Public Health. 4: 47-50.
  • Mustafa, Tehmina; Wiker, Harald G; Mørkve, Odd; Sviland, Lisbet. 2007. Reduced apoptosis and increased inflammatory cytokines in granulomas caused by tuberculous compared to non-tuberculous mycobacteria: role of MPT64 antigen in apoptosis and immune response. Clinical and Experimental Immunology. 150: 105-113. doi: doi:10.1111/j.1365-2249.2007.03476.x
  • Purohit, Manju Raj; Mustafa, Tehmina; Wiker, Harald G; Mørkve, Odd; Sviland, Lisbet. 2007. Immunohistochemical diagnosis of abdominal and lymph node tuberculosis by detecting Mycobacterium tuberculosis complex specific antigen MPT64. Diagnostic Pathology. 2. doi: 10.1186/1746-1596-2-36
  • Sviland, Lisbet; Mustafa, Tehmina; Purohit, Manju; Wiker, Harald G. 2007. Immunohistochemistry for the detection of Mycobacterium tuberculosis complex specific antigen (MPT64) improves the diagnosis of extrapulmonary tuberculosis caused by pathogenic mycobacteria. Acta Pathologica, Microbiologica et Immunologica Scandinavica (APMIS). 115: 1316-1316.
  • Mustafa, Tehmina; Mogga, Stanley Josephson; Mfinanga, Sayoki Godfrey M.; Mørkve, Odd; Sviland, Lisbeth. 2006. Immunohistochemical analysis of cytokines and apoptosis in tuberculous lymphadenitis. Immunology. 117: 454-462.
  • Mustafa, Tehmina; Wiker, Harald G; Mfinanga, Sayoki Godfrey M.; Mørkve, Odd; Sviland, Lisbet. 2006. Immunohistochemistry using a Mycobacterium tuberculosis complex specific antibody for improved diagnosis of tuberculous lymphadenitis. Modern Pathology. 19: 1606-1614.
  • Wiker, Harald G; Mustafa, Tehmina; Målen, Hiwa; Riise, Anne Ma Dyrhol. 2006. Vaccine approaches to prevent tuberculosis. Scandinavian Journal of Immunology. 64: 243-250. doi: 10.1111/j.1365-3083.2006.01815.x
  • Abebe, Feseha; Mustafa, Tehmina; Nerland, Audun H.; Bjune, Gunnar Aksel. 2005. Cytokine profile during latent and slowly progressive primary tuberculosis: a possible role for interleukin-15 in mediating clinical disease. Clinical and Experimental Immunology. 143: 180-192.
  • Mustafa, Tehmina; Mogga, Stanley Josephson; Mfinanga, Sayoki Godfrey M.; Mørkve, Odd; Sviland, Lisbeth. 2005. Significance of Fas and Fas ligand in tuberculous lymphadenitis. Immunology. 114: 255-262.
  • Mogga, Stanley J.; Mustafa, Tehmina; Sviland, Lisbeth; Nilsen, Rune. 2003. In situ expression of CD40, CD40L (CD154), IL-12, TNF-alpha, IFN-gamma and TGF-beta1 in murine lungs during slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 58: 327-334.
  • Mogga, Stanley J.; Mustafa, Tehmina; Sviland, L.; Nilsen, Rune. 2002. Increased Bcl-2 and reduced Bax expression in infected macrophages in slowly progressive primary murine mycobacterium tuberculosis infection. Scandinavian Journal of Immunology. 56: 383-391.
  • Mustafa, Tehmina; Bjune, Gunnar; Jonsson, Roland; Hernandez Pando, R.; Nilsen, Rune. 2001. Increased expression of fas ligand in human tuberculosis and leprosy lesions: a potential novel mechanism of immune evasion in mycobacterial infection. Scandinavian Journal of Immunology. 54: 630-639.
  • Mustafa, Tehmina.; Phyu, Sabai.; Nilsen, Rune Åkvik; Jonsson, Roland; Bjune, Gunnar Aksel. 2000. In situ expression of cytokines and cellular phenotypes in the lungs of mice with slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 51: 548-556.
  • Mustafa, Tehmina; Phyu, Sabai; Nilsen, Rune; Jonsson, Roland; Bjune, Gunnar. 2000. In Situ Expression of cytokines and cellular phenotypes in the lungs of mice with slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 51: 548-556.
  • Phyu, Sabai.; Tadesse, Azeb.; Mustafa, Tehmina.; Jonsson, Roland; Bjune, Gunnar Aksel. 2000. Diversity of lung and spleen immune responses in mice with slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 51: 147-154.
  • Phyu, Sabai; Tadesse, Azeb; Mustafa, Tehmina; Tadesse, S.; Jonsson, Roland; Bjune, Gunnar. 2000. Diversity of lung and spleen immune responses in mice with slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 51: 147-154.
  • Mustafa, Tehmina.; Phyu, Sabai.; Nilsen, Ragnhild; Bjune, Gunnar Aksel; Jonsson, Roland. 1999. Increased expression of FAS ligand on Mycobacterium tuberculosis infected macrophages: A potential novel mechansim of immune evasion by Mycobacterium tuberculosis? Inflammation. 23: 507-521.
  • Mustafa, Tehmina.; Phyu, Sabai.; Nilsen, Ragnhild; Jonsson, Roland; Bjune, Gunnar Aksel. 1999. A mouse model for slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 50: 127-136.
  • Mustafa, Tehmina; Phyu, Sabai; Nilsen, Rune; Bjune, Gunnar; Jonsson, Roland. 1999. Increased expresson of Fas ligand on Mycobacterium tuberculosis infected macrophages: a potential novel mechanism of immune evation by Mycobacterium tuberculosis? Inflammation. 23: 507-521.
  • Mustafa, Tehmina; Phyu, Sabai; Nilsen, Rune; Jonsson, Roland; Bjune, Gunnar. 1999. A mouse model for slowly proressing tuberculosis. Scandinavian Journal of Immunology. 50: 127-136.
  • Mustafa, Tehmina; Phyu, Sabai; Nilsen, Rune; Jonsson, Roland; Bjune, Gunnar. 1999. A mouse model for slowly progressive primary tuberculosis. Scandinavian Journal of Immunology. 50: 127-136.
  • Mustafa, Tehmina; Phyu, Sabai; Nilsen, Runse; Bjune, Gunnar; Jonsson, Roland. 1999. Increased expression of Fas ligand on Mycobacterium tuberculosis infected macrophages: a potential novel mechanism of immune evasion by Mycobacterium tuberculosis? Innflammation. 23: 507-521.
  • Phyu, Sabai.; Sørnes, S.; Mustafa, Tehmina.; Tadesse, Azeb.; Jonsson, Roland; Bjune, Gunnar Aksel. 1999. Changes in T-lymphocyte subsets in lungs and spleens of mice with slowly progressive primary Mycobacterium tuberculosis infection: Involvement of unconventional T-cell subsets. Scandinavian Journal of Immunology. 50: 137-144.
  • Phyu, Sabai; Sørnes, Steinar; Mustafa, Tehmina; Tadesse, Azeb; Jonsson, Roland; Bjune, Gunnar. 1999. Changes in T lymphocyte subsets in lungs and spleens of mice with slowly progressive primary mycobacterium tuberculosis infection: Involvement of unconventional T cell subsets. Scandinavian Journal of Immunology. 50: 137-144.
  • Phyu, Sabai; Sørnes, Steinar; Mustafa, Themina; Tadesse, Azeb; Jonsson, Roland; Bjune, Gunnar. 1999. Changes in T-Lymphocyte Subsets in Lungs and Spleens of Mice with Slowly Progressive Primary Mycobacterium tuberculosis Infection: Involvement of Unconventional T-Cell Subsets. Scandinavian Journal of Immunology. 50: 137-144.
  • Phyu, Sabai; Sørnes, Steinar; Tadesse, Azeb; Mustafa, Tehmina; Jonsson, Roland; Bjune, Gunnar. 1999. Changes in T lymphocyte subsets in lungs and spleens of mice with slowly progressive primary <I>Mycobacterium tuberculosis</I> infection: Involvement of unconventional T cell subsets. Scandinavian Journal of Immunology. 50: 137-144.
  • Phuy, S; Mustafa, Tehmina; Hofstad, Tor; Nilsen, Rune; Fosse, Richard; Bjune, Gunnar. 1998. A mouse models for latent tuberculosis. Scandinavian Journal of Infectious Diseases. 30: 59-69.
  • Phuy, Sabai; Mustafa, Tehmina; Hofstad, Tor; Nilsen, Rune; Fosse, Richard; Bjune, Gunnar. 1998. A Mouse Model for Latent Tuberculosis. Scandinavian Journal of Infectious Diseases. 30: 59-68.
  • Phyu, Sabai.; Mustafa, Tehmina.; Hofstad, Tor; Nilsen, Ragnhild; Fosse, Roar; Bjune, Gunnar Aksel. 1998. A mouse model for latent tuberculosis. Scandinavian Journal of Infectious Diseases. 30: 59-68.
  • Phyu, Sabai.; Mustafa, Tehmina.; Hofstad, Tor; Nilsen, Ragnhild; Fosse, Roar; Bjune, Gunnar Aksel. 1998. A mouse model for latent tuberculosis. Scandinavian Journal of Infectious Diseases. 39: 59-68.
Rapporter/avhandlinger
  • Mustafa, Tehmina. 2000. Murine models of chronic tuberculosis: significance of granuloma morphology, apoptosis and immune evasion.
Bokkapitler
  • Mustafa, Tehmina; Sviland, Lisbeth. 2004. Role of Fasligand/Fas system and apoptosis in the pathogenesis of tuberculosis. Role of Fasligand, sider 107-116. I:
    • Sharma, P. 2004. Tuberculosis: Current Research Trends. 200 sider.

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