Hjem
Yenan Brycesons bilde

Yenan Bryceson

Professor
  • E-postYenan.Bryceson@uib.no
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
  • Postadresse
    Postboks 7804
    5020 Bergen
Vitenskapelig artikkel
  • 2020. Diagnostic challenges for a novel SH2D1A mutation associated with X-linked lymphoproliferative disease. Pediatric Blood & Cancer. 1-5.
  • 2019. Progressive impairment of NK cell cytotoxic degranulation is associated with TGF-β1 deregulation and disease progression in pancreatic cancer. Frontiers in Immunology.
  • 2019. Dominant TOM1 mutation associated with combined immunodeficiency and autoimmune disease. NPJ GENOMIC MEDICINE. 1-7.
  • 2019. Determination of essential phenotypic elements of clusters in high-dimensional entities—DEPECHE. PLOS ONE. 1-15.
  • 2019. A novel disorder involving dyshematopoiesis, inflammation, and HLH due to aberrant CDC42 function. Journal of Experimental Medicine. 2778-2799.
  • 2018. The STAT4 SLE risk allele rs7574865[T] is associated with increased IL-12-induced IFN-γ production in t cells from patients with SLE. Annals of the Rheumatic Diseases. 1070-1077.
  • 2018. Serum cytokine measurements and biological therapy of psoriasis - Prospects for personalized treatment? Scandinavian Journal of Immunology. 1-7.
  • 2018. Screening for Wiskott-Aldrich syndrome by flow cytometry. Journal of Allergy and Clinical Immunology. 333-335.e8.
  • 2018. Phosphorylation of intracellular signaling molecules in peripheral blood cells from psoriasis patients on originator or biosimilar infliximab. British Journal of Dermatology. 371-380.
  • 2018. NK cell receptor NKG2D sets activation threshold for the NCR1 receptor early in NK cell development. Nature Immunology. 1083-1092.
  • 2018. Clonal expansion and compartmentalized maintenance of rhesus macaque NK cell subsets. Science immunology.
  • 2018. ARID5B regulates metabolic programming in human adaptive NK cells. Journal of Experimental Medicine. 2379-2395.
  • 2018. A RAB27A 5' untranslated region structural variant associated with late-onset hemophagocytic lymphohistiocytosis and normal pigmentation. Journal of Allergy and Clinical Immunology. 317-321.e8.
  • 2017. Unperturbed cytotoxic lymphocyte phenotype and function in myalgic encephalomyelitis/chronic fatigue syndrome patients. Frontiers in Immunology. 1-15.
  • 2017. Patients with primary Sjögren's syndrome have alterations in absolute quantities of specific peripheral leucocyte populations. Scandinavian Journal of Immunology. 491-502.
  • 2017. Natural killer cell biology illuminated by primary immunodeficiency syndromes in humans. Clinical Immunology. 29-42.
  • 2017. Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia. Leukemia. 1108-1116.
  • 2017. High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors. eLIFE.
  • 2017. Gain-of-function SAMD9L mutations cause a syndrome of cytopenia, immunodeficiency, MDS, and neurological symptoms. Blood. 2266-2279.
  • 2017. Differences in granule morphology yet equally impaired exocytosis among cytotoxic T cells and NK cells from Chediak-Higashi syndrome patients. Frontiers in Immunology.
  • 2017. CD49a Expression Defines Tissue-Resident CD8+ T Cells Poised for Cytotoxic Function in Human Skin. Immunity. 287-300.
  • 2017. Adaptive NK cells can persist in patients with GATA2 mutation depleted of stem and progenitor cells. Blood. 1927-1939.
  • 2017. Acquired somatic mutations in PNH reveal long-term maintenance of adaptive NK cells independent of HSPCs. Blood. 1940-1946.
  • 2016. The past, present, and future of NK cells in hematopoietic cell transplantation and adoptive transfer. Current Topics in Microbiology and Immunology. 225-243.
  • 2016. Reduced potency of cytotoxic T lymphocytes from patients with high-risk myelodysplastic syndromes. Cancer Immunology and Immunotherapy. 1135-1137.
  • 2016. Diversification and functional specialization of human NK cell subsets. Current Topics in Microbiology and Immunology. 63-93.
  • 2016. CD56dim CD57+ NKG2C+ NK cell expansion is associated with reduced leukemia relapse after reduced intensity HCT. Leukemia. 456-463.
  • 2015. Targeted high-throughput sequencing for genetic diagnostics of hemophagocytic lymphohistiocytosis. Genome Medicine.
  • 2015. Incidence and clinical presentation of primary hemophagocytic lymphohistiocytosis in Sweden. Pediatric Blood & Cancer. 346-352.
  • 2015. Functional anti-CD94/NKG2A and anti-CD94/NKG2C autoantibodies in patients with systemic lupus erythematosus. Arthritis & Rheumatology. 1000-1011.
  • 2015. Cytomegalovirus infection drives adaptive epigenetic diversification of NK cells with altered signaling and effector function. Immunity. 443-456.
  • 2014. Transcriptional regulation of Munc13-4 expression in cytotoxic lymphocytes is disrupted by an intronic mutation associated with a primary immunodeficiency. Journal of Experimental Medicine. 1079-1091.
  • 2014. Immunomodulatory activity of commonly used drugs on Fc-receptor-mediated human natural killer cell activation. Cancer Immunology and Immunotherapy. 627-641.
  • 2013. Surface CD107a/LAMP-1 protects natural killer cells from degranulation-associated damage. Blood. 1411-1418.
  • 2013. Development of classical Hodgkin's lymphoma in an adult with biallelic STXBP2 mutations. Haematologica. 760-764.
  • 2013. Comparison of primary human cytotoxic T-cell and natural killer cell responses reveal similar molecular requirements for lytic granule exocytosis but differences in cytokine production. Blood. 1345-1356.
Leserinnlegg
  • 2013. Novel deep intronic and missense UNC13D mutations in familial haemophagocytic lymphohistiocytosis type 3. British Journal of Haematology. 415-418.
Brev til redaktøren
  • 2015. Hemophagocytic lymphohistiocytosis in 2 patients with underlying IFN-γ receptor deficiency. Journal of Allergy and Clinical Immunology. 1638-1641e5.
  • 2014. Combined newborn screening for familial hemophagocytic lymphohistiocytosis and severe T- and B-cell immunodeficiencies. Journal of Allergy and Clinical Immunology. 226-228.e7.
Doktorgradsavhandling
  • 2019. Systemic inflammation in psoriasis: Circulating immune cells and cytokines.
Errata
  • 2019. Corrigendum: Unperturbed cytotoxic lymphocyte phenotype and function in myalgic encephalomyelitis/chronic fatigue syndrome patients. Frontiers in Immunology.
Vitenskapelig oversiktsartikkel/review
  • 2018. Natural killer cells in inflammation and autoimmunity. 37-46.
  • 2018. HLH: Genomics illuminates pathophysiological diversity. 5-7.
  • 2017. Natural killer cell-mediated immunosurveillance of human cancer. 20-29.
  • 2016. Natural killer cell memory in context. 368-376.
  • 2016. Epigenetic Regulation of Adaptive NK Cell Diversification. 451-461.
  • 2014. Pathophysiology and spectrum of diseases caused by defects in lymphocyte cytotoxicity. 10-17.
  • 2014. NK cell development and function - Plasticity and redundancy unleashed. 114-126.

Se fullstendig oversikt over publikasjoner i CRIStin.