- E-mailAurora.Martinez@uib.no
- Phone+47 55 58 64 27
- Visitor AddressJonas Lies vei 915009 Bergen
- Postal AddressPostboks 78045020 Bergen
Aurora Martinez is the leader of the research group Biorecognition that studies the relation between biomolecular structure and function to understand and develop new therapeutic options for genetic diseases, notably neurometabolic disorders such as phenylketonuria (PKU) and defects in dopamine synthesis.
Aurora is also a partner in the KG Jebsen Centre for neuropsychiatric disorders. In addition, she is also a partner in the project 'Molecular control of Arc protein: Decoding a master regulator of synaptic plasticity and cognition', coordinated by Clive Bramham, which received support from the Toppforsk Program (NFR).
- (2024). Tetrahydrobiopterin (BH<inf>4</inf>) treatment stabilizes tyrosine hydroxylase: Rescue of tyrosine hydroxylase deficiency phenotypes in human neurons and in a knock-in mouse model. The Journal of Inherited Metabolic Disease (JIMD).
- (2024). TPPU_DSF: A Web Application to Calculate Thermodynamic Parameters Using DSF Data. Journal of Molecular Biology (JMB).
- (2024). Mouse models for inherited monoamine neurotransmitter disorders. The Journal of Inherited Metabolic Disease (JIMD).
- (2023). Towards the therapeutic correction of mitochondrial Complex I deficiency in dopaminergic cell models.
- (2023). Screening for VMAT2 chaperones and activity modulators.
- (2023). Potassium channels in behavioral brain disorders. Molecular mechanisms and therapeutic potential: A narrative review. Neuroscience and Biobehavioral Reviews.
- (2023). One ring closer to a closure: the crystal structure of the ES<inf>3</inf> hydroxymethylbilane synthase intermediate. The FEBS Journal.
- (2023). Impact of small molecule-mediated inhibition of ammonia detoxification on lung malignancies and liver metabolism. Cancer Communications. 508-512.
- (2023). Effect of simulated saturation diving on dopamine synthesis regulation.
- (2022). High-throughput screening for VMAT2 activity modulators.
More information in national current research information system (CRIStin)
Fields of competence