Hjem
Universitetet i Bergen
Svein Are Mjøss bilde
Foto:
UiB

Svein Are Mjøs

Professor
Kjemisk institutt
  • E-postSvein.Mjos@uib.no
  • Telefon+47 55 58 35 53
  • Besøksadresse
    Allégaten 41
    Realfagbygget
    5007 Bergen
    Rom 
    3026 (3A2b)
  • Postadresse
    Postboks 7803
    5020 Bergen

Målet med min forskning innen analytisk kjemi er å maksimere informasjonen som kan hentes fra analytisk instrumentering ved bruk av kjemometri. 

Aktivitetene for å oppnå dette målet kan deles inn i følgende kategorier:

  • Ekstraksjon av informasjon fra spektra og kromatogrammer for bruk til kvantifisering og identifikasjon. Dette inkluderer teknikker som støyreduksjon, spektral sammenligning og oppløsning av overlappende signaler.
  • Prediksjon av kromatografisk retensjon og retensjonsbaserte metoder for identifikasjon.
  • Optimalisering og standardisering av kromatografiske betingelser ved hjelp av responsflate-metodikk.

I tillegg utvikler jeg også Matlab-basert programvare for kromatografi og massespektrometri som brukes i vår undervisning og forskning. Jeg vedlikeholder også en samling med kromatografiske og massespektrometriske data for fettsyre-metylestre.

Kurs

Jeg underviser i emnet KJEM/FARM250 (Analytisk Kjemi), KJEM350 (Kvantitativ organisk analyse) og EMQAL AM15. 

Masteroppgaver

Masteroppgaver innen kjemometri eller analytisk kjemi tilbys til studenter på masterprogrammene i kjemi og medisinsk teknologi
 
Mange av oppgavene utføres på eksterne laboratorier, typisk på Haukeland Sykehus eller Havforskningstinstituttet.

 

Utvalgte publikasjoner:

M.N. Chhaganlal, J. Underhaug, S.A. Mjøs*, Evaluation of NMR predictors for accuracy and ability to reveal trends in 1H NMR spectra of fatty acids, MAGNETIC RESONANCE IN CHEMISTRY 61 (2023) 318-332. DOI: 10.1002/mrc.5336

C.C. Lin, A. Sengee, S.A. Mjøs*, Minor compounds and potential interferents in gas chromatographic analyses of human serum fatty acids. JOURNAL OF CHROMATOGRAPHY B 1138 (2020) 121963. DOI: 10.1016/j.jchromb.2019.121963

H.D. Waktola, S.A. Mjøs*, Chromatographic efficiency of polar capillary columns applied for the analysis of fatty acid methyl esters by gas chromatography, JOURNAL OF SEPARATION SCIENCE 41 (2018) 1582-1592. DOI: 10.1002/jssc.201700908

Y. Zeng, S.A. Mjøs*, F.P.A. David, A.W. Schmid, Extension of least squares spectral resolution algorithm to high-resolution lipidomics data. ANALYTICA CHIMICA ACTA 914 (2016) 35-46. DOI: 10.1016/j.aca.2016.02.002

S.A. Mjøs*, H.D. Waktola, Optimizing the relationship between chromatographic efficiency and retention times in temperature-programmed gas chromatography. JOURNAL OF SEPARATION SCIENCE 38 (2015) 3014-3027. DOI: 10.1002/jssc.201500364

M. Chhaganlal, L.K. Skartland, S.A. Mjøs*, Transfer  of retention patterns in gas chromatography by means of response surface  methodology, JOURNAL OF CHROMATOGRAPHY A 1332 (2014) 64-72. DOI: 10.1016/j.chroma.2014.01.039

Z. Wasta, S.A. Mjøs*, A database of chromatographic properties and mass spectra of fatty acid methyl esters from omega-3 products. JOURNAL OF CHROMATOGRAPHY A 1299 (2013) 94-102. DOI: 10.1016/j.chroma.2013.05.056

Y. Zeng, S.A. Mjøs*, S. Meier, C. Lin, R. Vadla, Least squares spectral resolution of liquid chromatography-mass  spectrometry data of glycerophospholipids. JOURNAL OF CHROMATOGRAPHY A  1280 (2013) 23-34. DOI: 10.1016/j.chroma.2012.12.070

C. Sciotto, S.A. Mjøs*, Trans isomers of EPA and DHA in omega-3 products on the European market. LIPIDS 47 (2012) 659-667. DOI: 10.1007/s11745-012-3672-3

L.K. Skartland, S.A. Mjøs*, B. Grung, Experimental designs for modeling retention patterns and separation efficiency in analysis of fatty acid methyl esters by gas chromatography-mass spectrometry. JOURNAL OF CHROMATOGRAPHY A 1218 (2011) 6823-6831. DOI: 10.1016/j.chroma.2011.07.077

S.A. Mjøs*, B. Grung, A Rank annihilation approach to reducing the scan-effect in gas chromatography-mass spectrometry data. ANALYTICA CHIMICA ACTA 640 (2009) 33-39. DOI: 10.1016/j.aca.2009.03.011

S. Meier*, S.A. Mjøs, H. Joensen, O. Grahl-Nielsen, Validation of a one-step extraction/methylation method for determination of fatty acids and cholesterol in marine tissues. JOURNAL OF CHROMATOGRAPHY A 1104 (2006) 291-298. DOI: 10.1016/j.chroma.2005.11.045

S.A. Mjøs, S. Meier, S. Boitsov*, Alkylphenol retention indices. JOURNAL OF CHROMATOGRAPHY A 1123 (2006) 98-105. DOI: 10.1016/j.chroma.2006.05.002

S.A. Mjøs*, O. Grahl-Nielsen, Prediction of gas chromatographic retention of polyunsaturated fatty acid methyl esters. JOURNAL OF CHROMATOGRAPHY A 1110 (2006) 171-180. DOI: 10.1016/j.chroma.2006.01.092

S.A. Mjøs*, The prediction of fatty acid structure from selected ions in electron impact mass spectra of fatty acid methyl esters. EUROPEAN JOURNAL OF LIPID SCIENCE AND TECHNOLOGY 106 (2004) 550-560. DOI: 10.1002/ejlt.200401013

S.A. Mjøs*, Two-dimensional fatty acid retention indices. JOURNAL OF CHROMATOGRAPHY A 1061 (2004) 201-209. DOI: 10.1016/j.chroma.2004.11.025

S.A. Mjøs*, Identification of fatty acids in gas  chromatography by application of different temperature and pressure programs  on a single capillary column. JOURNAL OF CHROMATOGRAPHY A 1015 (2003)  151-161. DOI: 10.1016/S0021-9673(03)01240-8

S.A. Mjøs*, Spectral transformations for deconvolution methods applied on gas chromatography-mass spectrometry data. ANALYTICA CHIMICA ACTA 488 (2003) 231-241. DOI: 10.1016/S0003-2670(03)00679-2

S.A. Mjøs*, J. Pettersen, A rapid method for the analysis of hydrogenated  fats by GC with IR detection. JOURNAL OF THE AMERICAN OIL CHEMISTS  SOCIETY 80 (2003) 839-846. DOI: 10.1007/s11746-003-0783-0

Alle publikasjoner i Christin:

Vitenskapelig artikkel
  • Vis forfatter(e) (2023). Tissue accumulation of polystyrene microplastics causes oxidative stress, hepatopancreatic injury and metabolome alterations in Litopenaeus vannamei. Ecotoxicology and Environmental Safety.
  • Vis forfatter(e) (2023). Evaluation of NMR predictors for accuracy and ability to reveal trends in <sup>1</sup>H NMR spectra of fatty acids. Magnetic Resonance in Chemistry. 318-332.
  • Vis forfatter(e) (2022). Suspension-feeding benthic species’ physiological and microbiome response to salmon farming and associated environmental changes. Frontiers in Marine Science. 1-22.
  • Vis forfatter(e) (2021). Effects of fish farm activities on the sponge Weberella bursa, and its associated microbiota. Ecological Indicators. 13 sider.
  • Vis forfatter(e) (2020). Minor compounds and potential interferents in gas chromatographic analyses of human serum fatty acids. Journal of chromatography. B. 10 sider.
  • Vis forfatter(e) (2020). Effects of intact and hydrolysed blue whiting proteins on blood pressure and markers of kidney function in obese Zucker fa/fa rats. European Journal of Nutrition. 16 sider.
  • Vis forfatter(e) (2019). Effects of low doses of fish and milk proteins on glucose regulation and markers of insulin sensitivity in overweight adults: a randomised, double blind study. European Journal of Nutrition. 1-17.
  • Vis forfatter(e) (2018). Water-soluble fish protein intake led to lower serum and liver cholesterol concentrations in obese zucker fa/fa rats. Marine Drugs. 1-12.
  • Vis forfatter(e) (2018). Salmon fillet intake led to higher serum triacylglycerol in obese zucker Fa/Fa rats but not in normolipidemic Long-Evans rats. Nutrients. 1-13.
  • Vis forfatter(e) (2018). Intake of baked cod fillet resulted in lower serum cholesterol and higher long chain n-3 PUFA concentrations in serum and tissues in hypercholesterolemic obese Zucker fa/fa rats. Nutrients. 1-15.
  • Vis forfatter(e) (2018). Enhancing EPA Content in an Arctic Diatom: A Factorial Design Study to Evaluate Interactive Effects of Growth Factors. Frontiers in Plant Science. 1-11.
  • Vis forfatter(e) (2018). Comparing EPA production and fatty acid profiles of three Phaeodactylum tricornutum strains under western Norwegian climate conditions. Algal Research. 11-22.
  • Vis forfatter(e) (2018). Chromatographic efficiency of polar capillary columns applied for the analysis of fatty acid methyl esters by gas chromatography. Journal of Separation Science. 1582-1592.
  • Vis forfatter(e) (2017). Lipids of Dietzia sp. A14101. Part II: A study of the dynamics of the release of surface active compounds by Dietzia sp. A14101 into the medium. Chemistry and Physics of Lipids. 31-42.
  • Vis forfatter(e) (2017). Lipids of Dietzia sp. A14101. Part I: A study of the production dynamics of surface-active compounds. Chemistry and Physics of Lipids. 19-30.
  • Vis forfatter(e) (2017). High intake of fatty fish, but not of lean fish, improved postprandial glucose regulation and increased the n-3 PUFA content in the leucocyte membrane in healthy overweight adults: A randomised trial. British Journal of Nutrition. 1368-1378.
  • Vis forfatter(e) (2017). Effects of baked and raw salmon fillet on lipids and n-3 PUFAs in serum and tissues in Zucker fa/fa rats. Food & Nutrition Research (FNR). 1-12.
  • Vis forfatter(e) (2017). Bioprospecting North Atlantic microalgae with fast growth and high polyunsaturated fatty acid (PUFA) content for microalgae-based technologies. Algal Research. 392-401.
  • Vis forfatter(e) (2016). Specific metabolites in a Phaeodactylum tricornutum strain isolated from Western Norwegian fjord water. Marine Drugs. 17 sider.
  • Vis forfatter(e) (2016). Serum fatty acid and lipoprotein subclass concentrations and their associations in prepubertal healthy Norwegian children. Metabolomics.
  • Vis forfatter(e) (2016). Predictive associations between serum fatty acids and lipoproteins in healthy non-obese Norwegians: implications for cardiovascular health. Metabolomics.
  • Vis forfatter(e) (2016). Plackett-Burman design and fragmentation studies to assist the 1 comparison of techniques used to extract phospholipids prior to regiospecific characterization by liquid chromatography mass spectrometry. American Journal of Modern Chromatography. 1-22.
  • Vis forfatter(e) (2016). Methylmercury Increases and Eicosapentaenoic Acid Decreases the Relative Amounts of Arachidonic Acid-Containing Phospholipids in Mouse Brain. Lipids. 61-73.
  • Vis forfatter(e) (2016). Intensive lifestyle intervention provides rapid reduction of serum fatty acid levels in women with severe obesity without lowering omega-3 to unhealthy levels. Clinical Obesity. 259-267.
  • Vis forfatter(e) (2016). Extension of least squares spectral resolution algorithm to high-resolution lipidomics data. Analytica Chimica Acta. 35-46.
  • Vis forfatter(e) (2016). Dietary fish protein hydrolysates containing bioactive motifs affect serum and adipose tissue fatty acid compositions, serum lipids, postprandial glucose regulation and growth in obese Zucker fa/fa rats. British Journal of Nutrition. 1336-1345.
  • Vis forfatter(e) (2016). Changes in serum fatty acid and lipoprotein subclass concentrations from prepuberty to adulthood and during aging. Metabolomics. 10 sider.
  • Vis forfatter(e) (2016). Application of gas chromatography/tandem mass spectrometry to determine a wide range of petrogenic alkylated polycyclic aromatic hydrocarbons in biotic samples. Rapid Communications in Mass Spectrometry. 2052-2058.
  • Vis forfatter(e) (2016). An LC–MS-based lipidomics approach for studying the impact of dietary eicosapentaenoic acid on modulating methylmercury toxicity in mice. Metabolomics.
  • Vis forfatter(e) (2015). Variable Number of Tandem Repeats (VNTR) analysis of Flavobacterium psychrophilum from salmonids in Chile and Norway. BMC Veterinary Research.
  • Vis forfatter(e) (2015). Optimizing the relationship between chromatographic efficiency and retention times in temperature-programmed gas chromatography. Journal of Separation Science. 3014-3027.
  • Vis forfatter(e) (2015). Metabolic markers in blood can separate prostate cancer from benign prostatic hyperplasia. British Journal of Cancer. 1712-1719.
  • Vis forfatter(e) (2015). Fatty acids in bacterium Dietzia sp grown on simple and complex hydrocarbons determined as FAME by GC-MS. Chemistry and Physics of Lipids. 15-26.
  • Vis forfatter(e) (2015). Data on pigments and long-chain fatty compounds identified in Dietzia sp. A14101 grown on simple and complex hydrocarbons. Data in Brief. 622-629.
  • Vis forfatter(e) (2015). Changes in Serum Fatty Acid Levels During the First Year After Bariatric Surgery. Obesity Surgery.
  • Vis forfatter(e) (2014). Transfer of retention patterns in gas chromatography by means of response surface methodology. Journal of Chromatography A. 64-72.
  • Vis forfatter(e) (2014). Influence of type of raw material on fishmeal physicochemical properties, the extrusion process, starch gelatinization and physical quality of fish feed. Aquaculture Nutrition. 410-420.
  • Vis forfatter(e) (2014). Evaluation of the retention pattern on ionic liquid columns for gas chromatographic analyses of fatty acid methyl esters. Journal of Chromatography A. 83-91.
  • Vis forfatter(e) (2014). Effects of duodenal switch alone or in combination with sleeve gastrectomy on body weight and lipid metabolism in rats. Nutrition and Diabetes. 6 sider.
  • Vis forfatter(e) (2014). Determination of Omega-3 Fatty Acids in Fish Oil Supplements Using Vibrational Spectroscopy and Chemometric Methods . Applied Spectroscopy. 1190-1200.
  • Vis forfatter(e) (2014). A low dietary intake of cod protein is sufficient to increase growth, improve serum and tissue fatty acid compositions, and lower serum postprandial glucose and fasting non-esterified fatty acid concentrations in obese Zucker fa/fa rats. European Journal of Nutrition. 1151-1160.
  • Vis forfatter(e) (2013). Least squares spectral resolution of liquid chromatography-mass spectrometry data of glycerophospholipids. Journal of Chromatography A. 23-34.
  • Vis forfatter(e) (2013). Krill hydrolysate free amino acids responsible for feed intake stimulation in Atlantic salmon (Salmo salar). Aquaculture Nutrition. 47-61.
  • Vis forfatter(e) (2013). Impact of variability in fishmeal physicochemical properties on the extrusion process, starch gelatinization and pellet durability and hardness. Animal Feed Science and Technology. 77-84.
  • Vis forfatter(e) (2013). A database of chromatographic properties and mass spectra of fatty acid methyl esters from omega-3 products. Journal of Chromatography A. 94-102.
  • Vis forfatter(e) (2012). Trans isomers of EPA and DHA in Omega-3 products on the European market. Lipids. 659-667.
  • Vis forfatter(e) (2012). High growth rates in Atlantic salmon (Salmo salar L.) fed 7.5% fish meal in the diet. Micro-, ultra- and nano-filtration of stickwater and effects of different fractions and compounds on pellet quality and fish performance. Aquaculture. 134-146.
  • Vis forfatter(e) (2012). Efficiencies of three common lipid extraction methods evaluated by calculating mass balances of the fatty acids. Journal of Food Composition and Analysis. 198-207.
  • Vis forfatter(e) (2011). Trans Fatty Acid Analyses in Samples of Marine Origin: The Risk of False Positives. Journal of Agricultural and Food Chemistry. 3520-3531.
  • Vis forfatter(e) (2011). Experimental designs for modeling retention patterns and separation efficiency in analysis of fatty acid methyl esters by gas chromatography-mass spectrometry. Journal of Chromatography A. 6823-6831.
  • Vis forfatter(e) (2010). The vector of calibration ratios: A simple transfer method for mass spectra. Journal of Chromatography A. 5986-5994.
  • Vis forfatter(e) (2009). A Rank annihilation approach to reducing the scan-effect in gas chromatography-mass spectrometry data. Analytica Chimica Acta. 33-39.
  • Vis forfatter(e) (2008). Retention behavior of trans isomers of eicosapentaenoic and docosahexaenoic acid methyl esters on a polyethylene glycol stationary phase. European Journal of Lipid Science and Technology. 547-553.
  • Vis forfatter(e) (2007). Identification of estrogen-like alkylphenols in produced water from offshore oil installations. Marine Environmental Research. 651-655.
  • Vis forfatter(e) (2006). Validation of a one-step extraction/methylation method for determination of fatty acids and cholesterol in marine tissues. Journal of Chromatography A. 291-298.
  • Vis forfatter(e) (2006). Prediction of equivalent chain lengths from two-dimensional fatty acid retention indices. Journal of Chromatography A. 249-254.
  • Vis forfatter(e) (2006). Patterns in volatile components over heated fish powders. Food Research International. 190-202.
  • Vis forfatter(e) (2006). Geometrical isomerisation of double bonds in acid catalysed preparation of fatty acid methyl esters. European Journal of Lipid Science and Technology. 315-322.
  • Vis forfatter(e) (2006). Geometrical isomerisation of EPA and DHA at high temperatures. European Journal of Lipid Science and Technology. 589-597.
  • Vis forfatter(e) (2006). Alkylphenol retention indices. Journal of Chromatography A. 98-105.
  • Vis forfatter(e) (2005). Properties of trans isomers of eicosapentaenoic acid and eicosahexaenoic acid methyl esters on cyanopropyl stationary phases. Journal of Chromatography A. 185-192.
  • Vis forfatter(e) (2004). Two-dimensional fatty acid retention indices. Journal of Chromatography A. 201-209.
  • Vis forfatter(e) (2004). The prediction of fatty acid structure from selected ions in electron impact mass spectra of fatty acid methyl esters. European Journal of Lipid Science and Technology. 550-560.
  • Vis forfatter(e) (2004). Quantification of linolenic acid isomers by gas chromatography-mass spectrometry and deconvolution of overlapping chromatographic peaks. European Journal of Lipid Science and Technology. 307-318.
  • Vis forfatter(e) (2003). Spectral transformations for deconvolution methods applied on gas chromatography–mass spectrometry data. Analytica Chimica Acta. 231-241.
  • Vis forfatter(e) (2003). Identification of fatty acids in gas chromatography by application of different temperature and pressure programs on a single capillary column. Journal of Chromatography A. 151-161.
  • Vis forfatter(e) (2003). Determination of trans double bonds in polyunsaturated fatty acid methyl esters from their electron impact mass spectra. European Journal of Lipid Science and Technology. 156-164.
  • Vis forfatter(e) (2003). A rapid method for the analysis of hydrogenated fats by GC with IR detection. Journal of the American Oil Chemists Society. 839-846.
Doktorgradsavhandling
  • Vis forfatter(e) (2018). High-value fatty acids from microalgae. Bioprospecting and outdoor cultivation at northern latitudes.
  • Vis forfatter(e) (2015). Fishmeal physicochemical properties – Impact on the fish feed extrusion process, phase transitions and physical pellet quality.
  • Vis forfatter(e) (2015). Application of liquid chromatographymass spectrometry and chemometrics in the automated characterization of molecular lipid species.
  • Vis forfatter(e) (2006). Interpretation of chromatographic and mass spectrometric data from analyses of fatty acid methyl esters – Application of multivariate methods.

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