research project
ImSignal
This is a new project inspired by previous work of the group where proximity ligation assay (PLA) based detection of PD1-PDL1 interactions was found to provide a more refined patient stratification than PD-L1 protein alone (Lindberg et al., in preparation).
Hovedinnhold
Aiming to gather better insights into the resistance mechanisms towards immunotherapy in breast cancer, the ImSignal project intends to perform a highly multiplex detection of active immune checkpoint interactions in tissue samples by adapting the PLA to the Hyperion mass imager.
25.04.2023