Nyhetsarkiv for Neurotargeting forskningsgruppe

Ebselen bonding decreases stability of 14-3-3 proteins (09.09.2021)

Ebselen, a promising drug candidate against cancer, bipolar disorder and the virus infection Covid-19, covalently bonds to cysteine residues in 14-3-3 adaptor proteins, triggering 14-3-3 destabilization and degradation in cells and intact brain tissue when used in therapeutic concentrations, potentially explaining the behavioral and anti-neoplastic effects of this drug.

Funding for studies on biomembranes (05.09.2021)

Our research project BIOPROM (Biomimetic Proteolipid Multilayers - Structure and Properties) was awarded a research grant of 12 MNOK by the Research Council of Norway. The BIOPROM project will reveal unprecedented details of the molecular structure and properties of myelin, from the nano to the meso scale.