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Sigrid Aslaksens bilde
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Jørgen Barth

Sigrid Aslaksen

Postdoktor, Medical Genetics group
  • E-postSigrid.Aslaksen@uib.no
  • Besøksadresse
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen

Postdoc (2021-) in the Medical Genetics group focusing on functional characterization of ABCA4-variants linked to Stargardt disease and development of pharmacological chaperones. 

Ph.D. fellow (2017-2020) in the Endocrine Medicine research group, led by prof. Eystein S. Husebye, at the Department of Clinical Science, University of Bergen. Main research focus: Functional characterization of genetic risk factors in autoimmune Addison's disease and immunodominant T cell responses in patients with Addison's. 

Vitenskapelig artikkel
  • Vis forfatter(e) (2021). The polymorphism L412F in TLR3 inhibits autophagy and is a marker of severe COVID-19 in males. Autophagy.
  • Vis forfatter(e) (2021). 21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison’s Disease Are Restricted by HLA-A2 and HLA-C7 Molecules. Frontiers in Immunology. 12 sider.
  • Vis forfatter(e) (2019). Identification and characterization of rare Toll-like receptor 3 variants in patients with autoimmune Addison’s disease. Journal of translational autoimmunity.
  • Vis forfatter(e) (2019). Coexistence of congenital adrenal hyperplasia and autoimmune Addison's disease. Frontiers in Endocrinology. 1-5.
  • Vis forfatter(e) (2016). Versatile, sensitive liquid chromatography mass spectrometry–Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins. Scientific Reports. 10 sider.

Se fullstendig oversikt over publikasjoner i CRIStin.

Alexander Hellesen† , Sigrid Aslaksen†, Lars Breivik, Ellen Christine Røyrvik, Øyvind Bruserud, Kine Edvardsen, Karl Albert Brokstad, Anette Susanne Bøe Wolff, Eystein Sverre Husebye and Eirik Bratland (2021). †These authors have contributed equally to this work and share first authorship. 21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison’s Disease Are Restricted by HLA-A2 and HLA-C7 Molecules. Frontiers in Immunology, 12, 742848. 10.3389/fimmu.2021.742848

Sigrid Aslaksen, Anette B. Wolff, Magnus D. Vigeland, Lars Breivik, Ying Sheng, Bergithe E. Oftedal, Haydee Artaza, Beate Skinningsrud, Dag E. Undlien, Kaja K. Selmer, Eystein S. Husebye, Eirik Bratland (2019). Identification and characterization of rare Toll-like receptor 3 variants in patients with autoimmune Addison's disease. Journal of Translational Autoimmunity, 1, 100005. 10.1016/j.jtauto.2019.100005

Sigrid Aslaksen, Paal Methlie, Magnus D. Vigeland, Dag E. Jøssang, Anette B. Wolff, Ying Sheng, Bergithe E. Oftedal, Beate Skinningsrud, Dag E. Undlien, Kaja K. Selmer, Eystein S. Husebye, Eirik Bratland (2019). Coexistence of congenital adrenal hyperplasia and autoimmune Addison’s disease. Frontiers in Endocrinology, 10, 648. 10.3389/fendo.2019.00648

Tore Vehus, Hanne Røberg-Larsen, Jo Waaler, Sigrid Aslaksen, Stefan Krauss, Steven R. Wilson, Elsa Lundanes (2016). Versatile, sensitive liquid chromatography mass spectrometry – Implementation of 10 μm OT columns suitable for small molecules, peptides and proteins. Scientific Reports, 6, 37507. 10.1038/srep37507

 

 

 

Education/academic qualifications

Postdoctoral researcher, molecular genetics of patients with ABCA4-retinal dystrophies, University of Bergen, 2021. 

Philosophiae doctor (PhD), genetic risk factors in Autoimmune Addison's disease, University of Bergen, 2020. 

Practical-pedagogical education, Norwegian University of Life Sciences, 2017

Master’s degree, Biotechnology and Molecular Biology, Norwegian University of Life Sciences, 2016

Bachelor's degree, Biotechnology, Norwegian University of Life Sciences, 2014

 

Research visits

University of Oxford, Weatherall Institute of Molecular Medicine, UK

 

Grants

The Scandinavian Society for Immunology travel grants, 2019

Det alminnelige medisinske forskningsfond, 2018

Dr. Nils Henrichsen og hustru Anna Henrichsens legat, 2018

Trygve Tellefsens legat, 2015