Bergen Stress and Sleep Group, BSSG


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Anna Elfrida Hovde Vollsund

The relationship between shift work, sleep disturbances and oxidative stress in the brain



Sleep disturbances and sleep deprivation have been shown to increase markers of oxidative stress in the brain, however research on the effect of working night shifts on these markers are lacking. In my master project I am using an animal model of simulated shift work, where rats have been working 3 consecutive day or night shifts. I will look at different biomarkers for oxidative stress in the brain, using the ELISA method. The purpose of this project is to investigate if working night shifts could lead to elevated levels of oxidative stress in the brain, and if differences in sleep quality or quantity can explain these differences.

This master’s project was part of the project:
Consequences of night shift simulation on waking performance, sleep, circadian rhythmicity and brain function. 


Main supervisor  Torhild Pedersen
Co-supervisor Janne Grønli