Centre for Cancer Biomarkers


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Vision and research areas

CCBIO aims to discover, validate and translate cancer biomarkers to improve our understanding of tumor mechanisms, promote accurate diagnosis and stratification of cancer patients, and inform precise, cost-effective and responsible treatment of cancer.


CCBIO is especially focusing on the tumor microenvironment in primary and metastatic cancers, and how tissue context can instruct aggressive tumor traits and predict cancer behavior and prognosis. The center is studying how crosstalk between tumor cells and tumor microenvironment niches reflects functional cancer complexity and heterogeneity at various levels.

CCBIO concentrates on the following integrated and overlapping programs:

1. Mechanisms of Tumor-Microenvironment Interactions (Basic Studies)

2. Discovery and Validation of Cancer Biomarkers (Biomarker Mapping)

3. Clinical Applications and Early Trials (Clinical Studies)

4. Ethics, Economics and Priorities (Societal Studies)

Biomedical project areas are supplemented with integrated ethics and economics projects, focused on how to prioritize and fund expensive cancer treatment in the era of expanding and costly personalized medicine. Collaboration partners, both national and international, have been included to support these programs.

Research teams in these programs

For the second term (2018 - 2023), the organization of CCBIO has been modified to reflect the current research activities. We now have four teams and corresponding project areas, as can be seen in this link. On top of this, the four programs are supported by resources on bioinformatics and processing of big data, and Rolf Reed is strategic advisor. Increased collaboration within CCBIO, between the different teams and investigators, has taken place over the years. CCBIO is supported by an International Faculty of top scientists in different fields.