Nyhetsarkiv for Institutt for biomedisin

The Michael Sars Centre is launching a Visitors Program designed to foster scientific exchange and collaborations across disciplines.

Congratulations to Haya and Tyra!

Our group Biorecognition, along with collaborators in Madrid and Bilbao, Spain, has published a exciting new study by Mary Dayne S. Tai et al. in Nature Communications (link below).

CNPase is an enzyme present at high levels in myelinating cells. Novel nanobody tools developed in an international collaboration were used to identify binding epitopes at atomic resolution and visualise myelin. Additionally, the nanobodies were used as intrabodies to bind to CNPase in living cells. These nanotools will be valuable for future research on myelin and its molecules.

Aromatic amino acid hydroxylases (AAAHs) like PAH, TH, and TPH are essential for producing key neurotransmitters and require iron and tetrahydrobiopterin to function. This study screened 307 histone deacetylase inhibitors and found that compounds like panobinostat can inhibit AAAHs at low micromolar concentrations, suggesting new therapeutic applications for these inhibitors.

TargetRNA is an EU Horizon funded Marie Skłodowska-Curie Action (MSCA) doctoral training network. In this network, 16 PhD students will be trained in RNA-ligand design in the context of antimicrobial drug discovery.

BORTEM-17 interim analysis results and small molecule inhibitor targeting CSPG4/NG2 in glioblastoma at American Association for Cancer Research (AACR 2024) April 5-10, 2024

It was a great privilege to participate at ‘AACR Annual Meeting 2024’, a large and important conference for cancer research, the place where scientists, clinicians, survivors, and patients, gather to share and discuss the latest breakthroughs.