The Department of Biomedicine

News archive for The Department of Biomedicine

Today, Kalyani Mukherjee joined our group as a PhD student, funded by a stipend by the Sigrid Jusélius foundation.
Myelin is a crucial structure for the normal functioning of the vertebrate nervous system. Here, we have used multiple state-of-the-art technologies at large international research infrastructures, enabling methods not available in Norway, to obtain 3D structural information on some of the most hydrophobic protein molecules in the human body, which are responsible for the correct structure and... Read more
Nanobodies are single-domain fragments obtained from camelid antibodies, which have high affinity towards their target protein. Two recent publications describe the development and use of nanobodies directed against the neuronal Arc protein to promote both structure determination, imaging and detection, and functional studies.
On Wednesday June 1st, Isa defended her PhD at the University of Oulu. The opponent was Professor Alf Månsson from the Linnaeus University, Kalmar, Sweden. We all could enjoy an interesting dialogue on myosins and motility, and Isa rocked all the way. Thanks to everyone involved and huge congratulations to Dr. Isa Pires!
Isa's work on Plasmodium falciparum myosin B is out on the preprint server bioRxiv - just in time for her PhD defense. Hopefully soon in peer-reviewed form too.
One week to go to Isa's PhD defense!
This week, Jude Santhampillai joined our group in Oulu as an orientation student and will work for three weeks with Henni.
We have a new PhD thesis hanging out for public display in the Tree of Science at the FBMM, University of Oulu. On June 1st, Isa will defend her thesis "Structural and functional studies on Plasmodium actin-myosin class XIV motors". The opponent will be Professor Alf Månsson from the Linnaeus University, Kalmar, Sweden. Looking forward to an interesting examination - stay tuned!
This week, Maiken Fridal Trones is joining us as a MSc student in our lab in Bergen. She will be working on some interesting mutants of Plasmodium actin.
Malaria is one of the most devastating infectious diseases in the world. The parasites causing malaria move by gliding, for which force is generated by an unusual actomyosin motor. We have determined high-resolution cryo-EM structures of the parasite actomyosin and actin filaments and a lower resolution reconstructions of the myosin light chains in the complex.
A large EU consortium got funding to integrated services for combatting current and future infectious disease outbreaks. BiSS is part of this consortium and offers fragment screening.
Elaheh Mahootchi is defending her dissertation on 31.3.2022 at the University of Bergen with the title "Characterization of the PLP-dependent decarboxylases GADL1 and CSAD".
We are looking for a post-doctoral fellow or possibly a highly-qualified PhD student for a 3-year project (with an option for an extension of one year) in my group at the Faculty of Biochemistry and Molecular Medicine (FBMM), University of Oulu, Finland. The overall aim of my group is to understand the molecular mechanism of malaria parasite gliding motility. For this, we use a wide variety of... Read more
Our group in Oulu was granted 72000 € from the Sigrid Jusélius foundation for the period 1.5.2022-30.4.2023. This is the first year of three, so the total amount will be 216000 € over three years. This secures the future of our group in Oulu in a rather difficult financial situation. We feel utmost gratitude for the almost continuous support we have received for our work on malaria from the... Read more
This week, we have had the pleasure to welcome Léa Gelez as a trainee in our group in Oulu. Léa studies biology and biochemistry at the University of Lille in France and is currently doing an Erasmus exchange in Oulu. She will spend 8 weeks in our lab, learning and helping with actin mutagenesis and characterizing some interesting mutants.
In addition to the travel grant, this week brought us two other positive decisions for small-scale funding. We also got 60000 NOK for consumable costs from "Det alminnelige medisinske forskningsfond" of the UiB and Inari got 150000 NOK from the Meltzer Research Fund to be used for a sabbatical year, which hopefully will be granted for 2023. More on that later.
We’re so happy to have Lucia working with us in the Haavik lab this year. Check out her perspective on being a Fulbright Scholar.
Often our path seems rocky, at times completely lost, but sometimes we find pointers to some light at the end. Today, we were given a travel grant of 50000 NOK from the University of Bergen and the Meltzer Research Fund to enable data collection and collaborative visits to get some science done also this year.