The Department of Biomedicine

News archive for The Department of Biomedicine

We congratulate Marianne Hjellvik Hannisdal for this accolade, winning best poster prize at the medical faculty‘s research day, with over 30 talented phd fellows who presented their excellent research projects in the form of poster presentations!
On Tuesday August 15th, Devaki defended her PhD at the University of Oulu. The opponent was Associate Professor Beáta Bugyi from the University of Pécs Medical School, Pécs, Hungary. We all very much enjoyed an insightful discussion on actins, actin depolymerizing factors, and their roles in the malaria parasite. Thanks to everyone involved and huge congratulations to Dr. Devaki Lasiwa!
The impact of the most common protein modification, N-terminal acetylation, has remained a conundrum in the field since its very origin. A new UiB article adds a piece to this puzzle.
As part of a consortium lead by the EU-Openscreen head office with the overall goal to improve the services offered by EU-Openscreen, the Brenk group has got funding to work on Ribotacs. Ribotacs are small molecules that selectively bind RNAs and a RNAse and thus lead targeted RNA degradation. We look forward to a succesfull collaboration.
This month, Dr. Stanley Makumire joined our group as a post-doctoral fellow. We look forward to working together in the coming years!
In March, we had a Drug Discovery meeting to showcase the research that is going on Bergen and to connect the groups active in this area. Nearly 50 people had signed up of the meeting and we had 9 different talks covering topics from target discovery all the way to clinical trials.
The second excellent news of the day was that Jane and Aatos Erkko foundation in Finland has decided to support our work with a whole 842000 € in the next three years. This decision could not have been more welcome and secures the continuation of our work. I am utmost grateful to Jane and Aatos Erkko foundation and extremely relieved. I hope one day also Norwegian funding bodies will see some... Read more
Today brought some pretty awesome news. The first came in the wee hours, telling that Henni's collaborative paper with Maddy Dans from the lab of Paul Gilson from the Burnet Institute (and a number of other collaborators) was accepted for publication in PLoS Biology. Looking forward to see this great story on inhibitors of the malaria profilactin complex finally out soon! Many thanks and huge... Read more
Last week, we got two small positive funding decisions, as we got consumable and travel money both from the Meltzer Foundation (100000 NOK) and the UiB General Medical Fund (76720 NOK). Many thanks for both foundations for continuing to support our work!
Andrea's paper on the structure and cellular localization of malaria parasite actin II was accepted for publication in PLoS Pathogens today! The work was a huge long-term collaborative effort between our lab and the lab of Inga Sidén-Kiamos at IMBB-FORTH, Heraklion, Crete, and that of Peter Rosenthal at the Francis Crick Institute, London, UK.
Budding yeast is a useful model system in molecular biology. Here, researchers in Bergen and Ghent used it to define one of the most abundant protein modifications in eukaryotes: N-terminal acetylation.
Reviewers of the month, Dec 2022
After years of work, we finally can see what the apicomplexan glideosome-associated connector (GAC) really looks like! Check out our latest preprint presenting the structure in two drastically different conformations. Based on its structure, we suggest a role for GAC as an elastic spring helping parasite motility and invasion.
Ruth Brenk has given a brief update of the riboswitch research in our group at the Digital Breakfast organized by the the Center of Digital Life.
Andrea's work together with collaborators from IMBB-FORTH (Heraklion, Crete) and Francis Crick Institute (London, UK) on malaria parasite actin II is out in preprint form.
We are looking for a post-doctoral fellow for a 2.5-year project (possible extension for up to 1 year) in my group at the Faculty of Biochemistry and Molecular Medicine (FBMM), University of Oulu, Finland. Alternatively, an exceptionally highly-qualified PhD student could be considered. The overall aim of my group is to understand the molecular mechanism of malaria parasite gliding motility. To... Read more
Henni's recent work on characterizing compounds interfering with the malaria parasite profilin-actin complex and actin dynamics is out as a preprint on bioRxiv. The project is part of a large collaboration led by Madeline Dans and Paul Gilson from the Burnet Institute, Melbourne, Australia.