News archive for The Department of Biomedicine

Ine and Emilie were attending a project course priming them for lab work. They ended up co-developing a method to quality control a cell model which is used by thousands of researchers worldwide.

Professor Frits Thorsen and his research group at the ChiNor Research Laboratory has newly received a significant funding of 550 000 RMB over four years (equivalent to 200 000 NOK per year), from the China´s National Natural Science Foundation, for their ongoing research on exosome-derived miRNAs in brain metastases.

Several variants of the NAA10 gene have been found in patients suffering from developmental delay and hemihypertrophy. NAA10 steers the most common protein modification in humans: N-terminal acetylation.

BiSS is growing as a core facility, and we are quite happy that our users are satisfied.

Exosomes released from the primary tumour into circulation have been documented to promote pre-metastatic niche formation. We have identified a miRNA in exosomes from melanoma brain metastases that can play a vital role in this process. Knock-down (KD) of this miRNA results in an inhibition of brain metastatic growth. We are in the process of identifying potential drugs inhibiting the expression... Read more

During his Erasmus internship in the Arnesen lab, Tobias B. Beigl took great interest in his project on the recently identified NAA80 enzyme. Beigl was on an interesting and important research track and stayed on for a Master’s project trying to figure out why cells lacking NAA80 typically had a more fragmented Golgi apparatus. He recently published his findings in the scientific journal... Read more

Myelin, the insulative multilamellar sheath that enwraps axons, speeds up our nerve impulses by two orders of magnitude – a prerequisite for an efficient nervous system that we humans and other vertebrates enjoy. Myelin gains its structure and function from a high abundance of lipids and proteins, many of which are specific to this enigmatic biological system.