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ProtMetD: Protein Modifications, Metabolism and Disease

News archive for ProtMetD: Protein Modifications, Metabolism and Disease

Hypertension or high blood pressure is a major health problem that can result in cardiovascular diseases including hypertensive crisis and stroke. A recent paper in Science by Hwang and Varshavsky shows that the molecular signaling underlying regulation of blood pressure involves N-terminal acetylation of specific proteins and their consecutive degradation by the N-end rule pathway.