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Giovanni Occhipinti

Researcher
  • E-mailGiovanni.Occhipinti@uib.no
  • Phone+47 55 58 34 57
  • Visitor Address
    Realfagbygget, Allégt. 41
  • Postal Address
    Postboks 7803
    5020 BERGEN
Journal articles
  • Eliasson, Sondre H. Hopen; Chatterjee, Anamitra; Occhipinti, Giovanni; Jensen, Vidar Remi. 2019. Green Solvent for the Synthesis of Linear α-Olefins from Fatty Acids. ACS Sustainable Chemistry and Engineering. 7: 4903-4911. doi: 10.1021/acssuschemeng.8b05523
  • Renom-Carrasco, Marc; Mania, Philipp; Sayah, Reine; Veyre, Laurent; Occhipinti, Giovanni; Gajan, David; Lesage, Anne; Jensen, Vidar Remi; Thieuleux, Chloé. 2019. Supported Ru Olefin Metathesis Catalysts via a Thiolate Tether. Dalton Transactions. doi: 10.1039/C8DT04592E
  • Bailey, Gwendolyn A; Lummiss, Justin A M; Foscato, Marco; Occhipinti, Giovanni; McDonald, Robert; Jensen, Vidar Remi; Fogg, Deryn E. 2017. Decomposition of Olefin Metathesis Catalysts by Br?nsted Base: Metallacyclobutane Deprotonation as a Primary Deactivating Event. Journal of the American Chemical Society. 139: 16446-16449. doi: 10.1021/jacs.7b08578
  • Eliasson, Sondre H. Hopen; Chatterjee, Anamitra; Occhipinti, Giovanni; Jensen, Vidar Remi. 2017. The Mechanism of Rh-Catalyzed Transformation of Fatty Acids to Linear Alpha olefins. Inorganics. 5. doi: doi:10.3390/inorganics5040087
  • Engel, Julien; Smit, Wietse; Foscato, Marco; Occhipinti, Giovanni; Törnroos, Karl Wilhelm; Jensen, Vidar Remi. 2017. Loss and Reformation of Ruthenium Alkylidene: Connecting Olefin Metathesis, Catalyst Deactivation, Regeneration, and Isomerization. Journal of the American Chemical Society. 139: 16609-16619. doi: 10.1021/jacs.7b07694
  • Occhipinti, Giovanni; Törnroos, Karl Wilhelm; Jensen, Vidar Remi. 2017. Pyridine-Stabilized Fast-Initiating Ruthenium Monothiolate Catalysts for Z-Selective Olefin Metathesis. Organometallics. 36: 3284-3292. doi: 10.1021/acs.organomet.7b00441
  • Smit, Wietse; Koudriavtsev, Vitali; Occhipinti, Giovanni; Törnroos, Karl Wilhelm; Jensen, Vidar Remi. 2016. Phosphine-based Z-selective ruthenium olefin metathesis catalysts. Organometallics. 35: 1825-1837. doi: 10.1021/acs.organomet.6b00214
  • Foscato, Marco; Houghton, Benjamin J.; Occhipinti, Giovanni; Deeth, Robert J.; Jensen, Vidar Remi. 2015. Ring closure to form metal chelates in 3D fragment-based de novo design. Journal of Chemical Information and Modeling. 55: 1844-1856. Published 2015-09-01. doi: 10.1021/acs.jcim.5b00424
  • Foscato, Marco; Occhipinti, Giovanni; Venkatraman, Vishwesh; Alsberg, Bjørn Kåre; Jensen, Vidar Remi. 2014. Automated design of realistic organometallic molecules from fragments. Journal of Chemical Information and Modeling. 54: 767-780. doi: 10.1021/ci4007497
  • Foscato, Marco; Venkatraman, Vishwesh; Occhipinti, Giovanni; Alsberg, Bjørn Kåre; Jensen, Vidar Remi. 2014. Automated building of organometallic complexes from 3D fragments. Journal of Chemical Information and Modeling. 54: 1919-1931. doi: 10.1021/ci5003153
  • Heyndrickx, Wouter; Occhipinti, Giovanni; Jensen, Vidar Remi. 2014. Neutral nickel ethylene oligo- and polymerization catalysts: Towards computational catalyst prediction and design. Chemistry - A European Journal. 20: 7962-7978. doi: 10.1002/chem.201304889
  • Occhipinti, Giovanni; Koudriavtsev, Vitali; Törnroos, Karl Wilhelm; Jensen, Vidar Remi. 2014. Theory-assisted development of a robust and Z-selective olefin metathesis catalyst. Dalton Transactions. 43: 11106-11117. doi: 10.1039/c4dt00409d
  • Minenkov, Yury; Occhipinti, Giovanni; Jensen, Vidar Remi. 2013. Complete reaction pathway of ruthenium-catalyzed olefin metathesis of ethyl vinyl ether: kinetics and mechanistic insight from DFT. Organometallics. 32: 2099-2111. doi: 10.1021/om301192a
  • Occhipinti, Giovanni; Hansen, Fredrik Rosberg; Törnroos, Karl Wilhelm; Jensen, Vidar Remi. 2013. Simple and highly Z‑selective ruthenium-based olefin metathesis catalyst. Journal of the American Chemical Society. 135: 3331-3334. doi: 10.1021/ja311505v
  • Chu, Yunhan; Heyndrickx, Wouter; Occhipinti, Giovanni; Jensen, Vidar Remi; Alsberg, Bjørn Kåre. 2012. An evolutionary algorithm for de Novo optimization of functional transition metal compounds. Journal of the American Chemical Society. 134: 8885-8895. doi: 10.1021/ja300865u
  • Heyndrickx, Wouter; Occhipinti, Giovanni; Bultinck, Patrick; Jensen, Vidar Remi. 2012. Striking a compromise: polar functional group tolerance versus insertion barrier height for olefin polymerization catalysts. Organometallics. 31: 6022-6031. doi: 10.1021/om3000828
  • Minenkov, Yuriy Valerievich; Occhipinti, Giovanni; Heyndrickx, Wouter; Jensen, Vidar Remi. 2012. The nature of the barrier to phosphane dissociation from grubbs olefin metathesis catalysts. European Journal of Inorganic Chemistry. 2012: 1507-1516. doi: 10.1002/ejic.201100932
  • Minenkov, Yury; Singstad, Åsmund; Occhipinti, Giovanni; Jensen, Vidar Remi. 2012. The accuracy of DFT-optimized geometries of functional transition metal compounds: a validation study of catalysts for olefin metathesis and other reactions in the homogeneous phase. Dalton Transactions. 41: 5526-5541. doi: 10.1039/c2dt12232d
  • Heyndrickx, Wouter; Occhipinti, Giovanni; Minenkov, Yury; Jensen, Vidar Remi. 2011. Neutral Nickel Oligo- and Polymerization Catalysts: The Importance of Alkyl Phosphine Intermediates in Chain Termination. Chemistry - A European Journal. 17: 14628-14642. Published 2011-12-16. doi: 10.1002/chem.201101152
  • Occhipinti, Giovanni; Jensen, Vidar Remi. 2011. Nature of the Transition Metal-Carbene Bond in Grubbs Olefin Metathesis Catalysts. Organometallics. 30: 3522-3529. doi: 10.1021/om200181y
  • Occhipinti, Giovanni; Meermann, Christian; Dietrich, Hans Martin; Litlabø, Rannveig; Auras, Florian; Törnroos, Karl Wilhelm; Maichle-Mossmer, Cäcilia; Jensen, Vidar Remi; Anwander, Reiner. 2011. Synthesis and stability of homoleptic metal(III) tetramethylaluminates. Journal of the American Chemical Society. 133: 6323-6337. doi: 10.1021/ja2001049
  • Heyndrickx, Wouter; Occhipinti, Giovanni; Minenkov, Yury; Jensen, Vidar Remi. 2010. On the nature of the active site in ruthenium olefin coordination-insertion polymerization catalysts. Journal of Molecular Catalysis A: Chemical. 324: 64-74. doi: 10.1016/j.molcata.2010.03.023
  • Occhipinti, Giovanni; Liguori, Lucia; Tsoukala, Anna; Bjørsvik, Hans-Rene. 2010. A switchable oxidation process leading to two various versatile pharmaceutical intermediates. Organic Process Research & Development. 14: 1379-1384. doi: 10.1021/op100185x
  • Minenkov, Yury; Occhipinti, Giovanni; Jensen, Vidar Remi. 2009. Metal–ligand bond strengths of the transition metals. A challenge for DFT. Journal of Physical Chemistry A. 113: 11833-11844. doi: 10.1021/jp902940c
  • Occhipinti, Giovanni; Jensen, Vidar Remi; Törnroos, Karl Wilhelm; Frøystein, Nils Åge; Bjørsvik, Hans-Rene. 2009. Synthesis of a new bidentate NHC–Ag(I) complex and its unanticipated reaction with the Hoveyda–Grubbs first generation catalyst. Tetrahedron. 65: 7186-7194. doi: 10.1016/j.tet.2009.05.095
  • Tsoukala, Anna; Liguori, Lucia; Occhipinti, Giovanni; Bjørsvik, Hans-Rene. 2009. A novel simple and efficient bromination protocol for activated arenes. Tetrahedron Letters. 50: 831-833. doi: 10.1016/j.tetlet.2008.12.016
  • Occhipinti, Giovani; Jensen, Vidar Remi; Bjørsvik, Hans-Rene. 2007. Green and efficient synthesis of bidentate Schiff base Ru catalysts for olefin metathesis. Journal of Organic Chemistry. 72: 3561-3564. doi: 10.1021/jo070164z
  • Occhipinti, Giovanni; Bjørsvik, Hans-Rene; Törnroos, Karl Wilhelm; Fürstner, Alois; Jensen, Vidar Remi. 2007. The first imidazolium-substituted metal alkylidene. Organometallics. 26: 4383-4385. doi: 10.1021/om700590v
  • Occhipinti, Giovanni; Bjørsvik, Hans-Rene; Törnroos, Karl Wilhelm; Jensen, Vidar Remi. 2007. Ruthenium alkylidene complexes of Chelating amine Ligands. Organometallics. 26: 5803-5814. doi: 10.1021/om070219nS0276-7333(07)00219-1
  • Occhipinti, Giovani; Bjørsvik, Hans-Rene; Jensen, Vidar Remi. 2006. Quantitative structure-activity relationships of ruthenium catalysts for olefin metathesis. Journal of the American Chemical Society. 128: 6952-6964. doi: 10.1021/ja060832i
  • Bjørsvik, Hans-Rene; Occhipinti, Giovani; Gambarotti, Cristian; Cerasino, Leonardo; Jensen, Vidar Remi. 2005. Synthesis of methoxy-substituted phenols by peracid oxidation of the aromatic ring. Journal of Organic Chemistry. 70: 7290-7296.
Reports and theses
  • Occhipinti, Giovanni. 2007. Theory-assisted prediction and synthesis of ruthenium alkylidene complexes for olefin metathesis. University of Bergen, Bergen.

More information in national current research information system (CRIStin)

Publications in peer-reviewed scientific journals

1.     Automated Building of Organometallic Complexes from 3D Fragments.
Foscato, M.; Venkatraman V.; Occhipinti, G.;Alsberg, B. K.; Jensen, V. R. J. Chem. Inf. Model. 2014, 54, 1919-1931.

2.      Theory-Assisted Development of a Robust and Z-Selective Olefin Metathesis Catalyst.
Occhipinti, G.; Vitali Koudriavtsev, V.; Törnroos, K. W.; Jensen. V. R., Dalton Trans., 2014, 43, 11106-11117.

3.      Neutral Nickel Ethylene Oligo- and Polymerization Catalysts: Towards Computational Catalyst Prediction and Design.
Heyndrickx, W.; Occhipinti, G.; Jensen, V. R.Chem. Eur. J.,201420, 7962-7978.

4.      Automated design of realistic organometallic molecules from fragments.

Foscato, M.; Occhipinti, G.; Venkatraman, V.; Alsberg, B. K.; Jensen, V. R.J. Chem. Inf. Model. 2014, 54, 767-780.

5.      The Complete Reaction Pathway of Ruthenium-Catalyzed Olefin Metathesis of Ethyl Vinyl Ether: Kinetics and Mechanistic Insight from DFT.
Minenkov, Y.; Occhipinti, G.; Jensen, V. R.Organometallics, 2013, 32,2099-2111.

6.      Simple and Highly Z-Selective Ruthenium-Based Olefin Metathesis Catalyst.
Occhipinti, G.; Hansen, F.; Törnroos, K. W.; Jensen. V. R.J. Am. Chem. Soc., 2013, 135, 3331−3334.

7.      Striking a Compromise: Polar Functional Group Tolerance versus Insertion Barrier Height for Olefin Polymerization Catalysts.
Heyndrickx, W.; Occhipinti, G.; Bultinck, P.; Jensen, V. R.Organometallics, 2012, 31, 6022−6031.

8.      An Evolutionary Algorithm for de Novo Optimization of Functional Transition Metal Compounds.
Chu, Y.; Heyndrickx, W.; Occhipinti, G.; Jensen, V. R.; Alsberg, B. K. J. Am. Chem. Soc., 2012, 134, 8885−8895.

9.      The accuracy of DFT-optimized geometries of functional transition metal compounds: A validation study of catalysts for olefin metathesis and other reactions in the homogeneous phase.
Minenkov, Y.; Singstad, Å.; Occhipinti, G.; Jensen, V. R. Dalton Trans., 2012, 41, 5526-5541.  

10.  Nature of the Barrier to Phosphine Dissociation from Grubbs Olefin Metathesis Catalysts.
Minenkov, Y.; Occhipinti, G.; Heyndrickx, W.; Jensen, V. R. Eur. J. Inorg. Chem., 2012, 1507-1516.

11.  Neutral Nickel Oligo- and Polymerization Catalysts: The Importance of Alkyl Phosphine Intermediates in Chain Termination.
Heyndrickx, W.; Occhipinti, G.; Minenkov, Y.; Jensen, V. R.Chem. Eur. J.,2011, 17,14628-14642.

12.  The Nature of the Transition Metal—Alkylidene Bond in Grubbs Catalysts for Olefin Metathesis.
Occhipinti, G.; Jensen, V.R., Organometallics, 2011, 30, 3322-3529.

13.  Synthesis and Stability of Homoleptic Metal(III) Tetramethylaluminates.
Occhipinti, G.; Meermann, C.; Dietrich, M. H.; Litlabø, R.; Auras, F.; Karl W. Törnroos, K. W.;  Maichle-Mössmer, C.; Jensen, V. R.; Anwander, R. J. Am. Chem. Soc. 2011, 133, 6323-6337.

14.  A Switchable Oxidation Process Leading to Two Various Versatile Pharmaceutical
Intermediates
.
Occhipinti, G.; Liguori, L.; Tsoukala, A.; Bjørsvik, H.-R.Org. Process. Res. Dev.,2010, 14, 1387-1392.

15.  On the Nature of the Active Site in Ruthenium Olefin Coordination-Insertion Polymerization Catalysts.
Heyndrickx, W.; Occhipinti, G.; Minenkov, Y.; Jensen, V. R.J. Mol. Cat. A: Chem,2010,324, 64-74.

16.  Metal–Ligand Bond Strengths of the Transition Metals. A Challenge for DFT.
Minenkov, Y.; Occhipinti, G.; Jensen, V. R. J. Phys. Chem. A, 2009, 113, 11833-11844.

17.  Synthesis of a New Bidentate NHC Ag(I) Complex and its Unanticipated Reaction with the Hoveyda-Grubbs First Generation Catalyst.
Occhipinti, G., Jensen, V. R.; Törnroos, K. W.; Frøystein, N. Å.; Bjørsvik, H.-R.Tetrahedron, 2009, 113, 7186-7194.

18.  A Novel Simple and Efficient Bromination Protocol for Activated Arenes.
Tsoukala, A.; Liguori, L.; Occhipinti, G.; Bjorsvik, H.-R. Tetrahedron Letters, 2009, 50, 831-833.

19.  Ruthenium Alkylidene Complexes of Chelating Amine Ligands.
Occhipinti, G.; Bjørsvik, H.-R.; Törnroos, H.-R.; Jensen, V. R.Organometallics, 2007, 26, 5803-5814.

20.  The First Imidazolium-Substituted Metal Alkylidene.
Occhipinti, G.; Bjørsvik, H.-R.; Törnroos, K. W.; Fürstner, A.; Jensen, V. R. Organometallics, 2007, 26, 4383-4385.

21.  Green and Efficient Synthesis of Bidentate Schiff Base Ru Catalysts for Olefin Metathesis.
Occhipinti, G.; Jensen, V. R.; Bjørsvik, H.-R. J. Org. Chem., 2007, 72, 3561–3564.

22.  Quantitative Structure–Activity Relationships of Ruthenium Catalysts for Olefin Metathesis.
Occhipinti, G.; Bjørsvik, H.-R.; Jensen, V. R. J. Am. Chem. Soc. 2006, 128, 6952–6964.

23.  Synthesis of Methoxy-Substituted Phenols by Peracid Oxidation of the Aromatic Ring.
Bjørsvik, H.-R.; Occhipinti, G.; Gambarotti, C.; Cerasino, L.; Jensen, V. R. J. Org. Chem. 2005, 70, 7290-7296.

 

Patents

1.      Jensen, V. R.; Occhipinti, G. Ruthenium and Osmium Heterocyclic Carbene Metathesis Catalysts. Eur. Pat. Appl. EP 2826783 A1 20150121, 2015; U.S. Pat. Appl. Publ. US 2015025212, 2015; Chin. Pat. Appl. CN 104292273 A 20150121, 2015.

2.      Jensen, V. R.; Occhipinti, G. ; Hansen, F. Novel Olefin Metathesis Catalysts. Int. Patent Appl. WO 2012032131, 2012.

 

PhD thesis

Giovanni Occhipinti.
Theory-Assisted Prediction and Synthesis of Ruthenium Alkylidene Complexes for Olefin Metathesis.
Department of Chemistry, University of Bergen, June 2007. ISBN: 9788230804025.