Home
Giovanni Occhipinti's picture

Giovanni Occhipinti

Researcher
  • E-mailGiovanni.Occhipinti@uib.no
  • Phone+47 55 58 34 57
  • Visitor Address
    Realfagbygget, Allégt. 41
  • Postal Address
    Postboks 7803
    5020 BERGEN
Academic article
  • 2020. Z-Selective Monothiolate Ruthenium Indenylidene Olefin Metathesis Catalysts. Organometallics. 397-407.
  • 2020. Silica-supported Z-selective Ru olefin metathesis catalysts. Journal of Molecular Catalysis A: Chemical.
  • 2020. Ethylene-Triggered Formation of Ruthenium Alkylidene from Decomposed Catalyst. ACS Catalysis. 6788-6797.
  • 2019. Supported Ru Olefin Metathesis Catalysts via a Thiolate Tether. Dalton Transactions. 2886-2890.
  • 2019. Green Solvent for the Synthesis of Linear α-Olefins from Fatty Acids. ACS Sustainable Chemistry and Engineering. 4903-4911.
  • 2017. The Mechanism of Rh-Catalyzed Transformation of Fatty Acids to Linear Alpha olefins. Inorganics.
  • 2017. Pyridine-Stabilized Fast-Initiating Ruthenium Monothiolate Catalysts for Z-Selective Olefin Metathesis. Organometallics. 3284-3292.
  • 2017. Loss and Reformation of Ruthenium Alkylidene: Connecting Olefin Metathesis, Catalyst Deactivation, Regeneration, and Isomerization. Journal of the American Chemical Society. 16609-16619.
  • 2017. Decomposition of Olefin Metathesis Catalysts by Br?nsted Base: Metallacyclobutane Deprotonation as a Primary Deactivating Event. Journal of the American Chemical Society. 16446-16449.
  • 2016. Phosphine-based Z-selective ruthenium olefin metathesis catalysts. Organometallics. 1825-1837.
  • 2015. Ring closure to form metal chelates in 3D fragment-based de novo design. Journal of Chemical Information and Modeling. 1844-1856.
  • 2014. Theory-assisted development of a robust and Z-selective olefin metathesis catalyst. Dalton Transactions. 11106-11117.
  • 2014. Neutral nickel ethylene oligo- and polymerization catalysts: Towards computational catalyst prediction and design. Chemistry - A European Journal. 7962-7978.
  • 2014. Automated design of realistic organometallic molecules from fragments. Journal of Chemical Information and Modeling. 767-780.
  • 2014. Automated building of organometallic complexes from 3D fragments. Journal of Chemical Information and Modeling. 1919-1931.
  • 2013. Simple and highly Z‑selective ruthenium-based olefin metathesis catalyst. Journal of the American Chemical Society. 3331-3334.
  • 2013. Complete reaction pathway of ruthenium-catalyzed olefin metathesis of ethyl vinyl ether: kinetics and mechanistic insight from DFT. Organometallics. 2099-2111.
  • 2012. The nature of the barrier to phosphane dissociation from grubbs olefin metathesis catalysts. European Journal of Inorganic Chemistry (EurJIC). 1507-1516.
  • 2012. The accuracy of DFT-optimized geometries of functional transition metal compounds: a validation study of catalysts for olefin metathesis and other reactions in the homogeneous phase. Dalton Transactions. 5526-5541.
  • 2012. Striking a compromise: polar functional group tolerance versus insertion barrier height for olefin polymerization catalysts. Organometallics. 6022-6031.
  • 2012. An evolutionary algorithm for de Novo optimization of functional transition metal compounds. Journal of the American Chemical Society. 8885-8895.
  • 2011. Synthesis and stability of homoleptic metal(III) tetramethylaluminates. Journal of the American Chemical Society. 6323-6337.
  • 2011. Neutral Nickel Oligo- and Polymerization Catalysts: The Importance of Alkyl Phosphine Intermediates in Chain Termination. Chemistry - A European Journal. 14628-14642.
  • 2011. Nature of the Transition Metal-Carbene Bond in Grubbs Olefin Metathesis Catalysts. Organometallics. 3522-3529.
  • 2010. On the nature of the active site in ruthenium olefin coordination-insertion polymerization catalysts. Journal of Molecular Catalysis A: Chemical. 64-74.
  • 2010. A switchable oxidation process leading to two various versatile pharmaceutical intermediates. Organic Process Research & Development. 1379-1384.
  • 2009. Synthesis of a new bidentate NHC–Ag(I) complex and its unanticipated reaction with the Hoveyda–Grubbs first generation catalyst. Tetrahedron. 7186-7194.
  • 2009. Metal–ligand bond strengths of the transition metals. A challenge for DFT. Journal of Physical Chemistry A. 11833-11844.
  • 2009. A novel simple and efficient bromination protocol for activated arenes. Tetrahedron Letters. 831-833.
  • 2007. The first imidazolium-substituted metal alkylidene. Organometallics. 4383-4385.
  • 2007. Green and efficient synthesis of bidentate Schiff base Ru catalysts for olefin metathesis. Journal of Organic Chemistry. 3561-3564.
  • 2005. Synthesis of methoxy-substituted phenols by peracid oxidation of the aromatic ring. Journal of Organic Chemistry. 7290-7296.
Lecture
  • 2017. Loss and Reformation of Ruthenium Alkylidene: Connecting Olefin Metathesis, Deactivation, Regeneration, and Isomerization.
  • 2016. Computational Design of Functional Organometallic Complexes.
  • 2014. Theory-Assisted Development of Z-selective Olefin Metathesis Catalysts.
  • 2014. Theory-Assisted Development of Z-Selective Olefin Metathesis Catalysts.
Academic lecture
  • 2019. Toward E-selective Olefin Metathesis.
  • 2017. The Mechanism of Rh-Catalyzed Transformation of Fatty Acids to Alpha-olefins; A DFT-Study.
  • 2017. Loss and Reformation of Ruthenium Alkylidene: Connecting Olefin Metathesis, Catalyst Deactivation, Regeneration, and Isomerization.
  • 2016. Phosphine-Based Z-Selective Ruthenium Olefin Metathesis Catalysts.
  • 2016. Fast Initiating and Z-Selective Olefin Metathesis Catalysts: Yields, Functional Group Tolerance, and Application to RCM.
  • 2015. Theory-Assisted Design of Z-selective Olefin Metathesis Catalysts.
  • 2015. Phosphine-Based Z-Selective Ruthenium Olefin Metathesis Catalysts.
  • 2015. How to Teach Z Selectivity to Grubbs Catalysts.
  • 2015. How to Teach Z Selectivity to Grubbs Catalysts.
  • 2015. Computationally Driven Development of Z-Selective Olefin Metathesis Catalysts.
  • 2015. Automated design of realistic organometallic complexes and catalysts.
  • 2015. Automated Prediction of Optimized Ruthenium Catalysts for Olefin Metathesis.
  • 2015. Automated Prediction of Optimized Ruthenium Catalysts for Olefin Metathesis.
  • 2014. Theory-Assisted Discovery and Development of Z-Selective Olefin Metathesis Catalyst.
  • 2014. Automated in Silico Design of Homogeneous Catalysts.
  • 2013. Z-selective ruthenium-based olefin metathesis catalysts.
  • 2013. Novel and Robust Z-selective Olefin Metathesis Catalysts.
  • 2012. Z-selective ruthenium-based catalysts for olefin metathesis.
  • 2012. Theory-assisted design of homogeneous catalysts: New strategies.
  • 2012. Simple and Highly Z-Selective Ruthenium Olefin Metathesis Catalysts.
  • 2011. Ruthenium Metathesis Catalysts Bearing β-Carboline Ligands.
  • 2011. Ruthenium Metathesis Catalysts Bearing 2-substituted β-Carboline Ligands.
  • 2010. The nature of the barrier to phosphine dissociation from Grubbs olefin metathesis catalysts.
  • 2010. The Stability of Metal(III) Tetramethylaluminates for Olefin Polymerization: a QSPR/DFT Study.
  • 2010. Neutral Ni oligo- and polymerization catalysts: A novel termination pathway decides the chain length.
  • 2009. The polar functional group tolerance of transition metal catalysts for olefin polymerization.
  • 2009. The nature of the transition metal—alkylidene bond in Grubbs catalysts for olefin metathesis.
  • 2009. The mechanism of phosphine dissociation in Grubbs catalysts for olefin metathesis.
  • 2009. The Nature of the Metal—Alkylidene Bond in Grubbs Catalysts for Olefin Metathesis.
  • 2009. Accurate Enthalpies and Free Energies of Activation for Phosphine Dissociation in Grubbs’ Olefin Metathesis Catalysts.
  • 2008. Metal—ligand bond strengths of the transition metals. A challenge for DFT.
  • 2008. Insight into the coordination-insertion copolymerization of ethylene with methyl acrylate.
  • 2007. Theory-Assisted Development of Catalysts for Olefin Metathesis.
  • 2007. QSAR/DFT approach to insight and prediction of olefin metathesis catalysts.
Doctoral dissertation
  • 2007. Theory-assisted prediction and synthesis of ruthenium alkylidene complexes for olefin metathesis.
Poster
  • 2019. Z-Selective Ru-Indenylidene Olefin Metathesis Catalysts with remarkable structural features.
  • 2019. Toward E-selective Olefin Metathesis.
  • 2019. Toward E-selective Olefin Metathesis.
  • 2019. Toward E-Selectivity in Olefin Metathesis.
  • 2019. Selective reduction of phenol to benzene via loss of substrate aromaticity.
  • 2019. Reviving Metathesis: Ethylene-Triggered Formation of Ruthenium-Alkylidene .
  • 2019. A Nb2O5-Supported Iridium-Based Catalyst for Hydrodeoxygenation of Lignin-Derived Model Compounds .
  • 2018. Platinum Nanoparticles Immobilized on Alumina: A Highly Selective, Reusable Catalyst for the Hydrogenation of Arenols and Aryl ethers Under Mild and Neat Reaction Conditions .
  • 2018. A niobia-supported iridium-based catalyst for deoxygenation of lignin-derived model compounds.
  • 2018. A niobia-supported iridium-based catalyst for deoxygenation of lignin-derived model compounds.
  • 2018. A Niobia-Supported Iridium-Based Catalyst for Deoxygenation of Lignin-Derived Model Compounds.
  • 2018. A Nb2O5-Supported Iridium-Based Catalyst for Hydrodeoxygenation of Lignin-Derived Model Compounds .
  • 2017. Z-selective Ru indenylidene olefin metathesis catalysts.
  • 2017. Z-Selective Ru olefin metathesis catalysts supported on mesostructured silica.
  • 2017. Mechanisms Connecting Olefin Metathesis, Catalyst Deactivation, Regeneration, and Isomerization.
  • 2017. In Silico Evaluation of Olefin Metathesis Catalysts: the Importance of Monitoring More than One Elementary Reaction.
  • 2015. Theory-Assisted Discovery of Z-Selective Olefin Metathesis Catalysts.
  • 2015. Phosphine-Based Z-Selective Ruthenium Olefin Metathesis Catalysts.
  • 2014. Automated Design of Organometallic Compounds from 3D Fragments.
  • 2013. QSPR-Guided de novo Design of Organic Photovoltaic Dyes.
  • 2013. Automatic building of transition metal compounds from fragments: a class-based approach.
  • 2012. DENOPTIM: De novo OPTimization of Inorganic Molecules.
  • 2012. DENOPTIM: De novo OPTimization of Inorganic Molecules.
  • 2010. Phosphine Dissociation in Grubbs Catalysts for Olefin Metathesis: Evidence for Activation.
  • 2010. Neutral Ni oligo- and polymerization catalysts: New insight from computational chemistry.
  • 2010. A Green and Efficient Bromination Process.
  • 2009. The polar functional group tolerance of olefin polymerization catalysts.
  • 2009. The polar functional group tolerance of olefin polymerization catalysts.
  • 2009. The Stability of Metal(III) Tetramethylaluminates: a QSPR/DFT Study.
  • 2009. Metal-Phosphine Bonds Strengths of the Transition Metals: A Challenge for DFT.
  • 2009. A Green and Efficient Bromination Process.
  • 2008. The first imidazolium-substituted metal alkylidene.
  • 2008. Sc(AlMe4)3 – Enfant Terrible!
  • 2008. Sc(AlMe4)3 - L’Enfant Terrible!
  • 2008. Olefin Metathesis in Continuous Flow by means of the Novel Fluens Synthesis Multi-Jet Oscillating Disk (MJOD) milli-Reactor System.
  • 2008. Metal—ligand bond strengths of the transition metals. A challenge for DFT.
  • 2007. Olefin Metathesis in Continuous Flow by means of the Novel Fluens Synthesis Multi-Jet Oscillating Disk milli-Reactor System.
  • 2006. Design of Catalysts for Olefin Metathesis: Development and Application of a Novel QSAR/DFT-Strategy.
Academic literature review
  • 2007. Ruthenium alkylidene complexes of Chelating amine Ligands. 5803-5814.
  • 2006. Quantitative structure-activity relationships of ruthenium catalysts for olefin metathesis. 6952-6964.

More information in national current research information system (CRIStin)

Publications in peer-reviewed scientific journals

1.     Automated Building of Organometallic Complexes from 3D Fragments.
Foscato, M.; Venkatraman V.; Occhipinti, G.;Alsberg, B. K.; Jensen, V. R. J. Chem. Inf. Model. 2014, 54, 1919-1931.

2.      Theory-Assisted Development of a Robust and Z-Selective Olefin Metathesis Catalyst.
Occhipinti, G.; Vitali Koudriavtsev, V.; Törnroos, K. W.; Jensen. V. R., Dalton Trans., 2014, 43, 11106-11117.

3.      Neutral Nickel Ethylene Oligo- and Polymerization Catalysts: Towards Computational Catalyst Prediction and Design.
Heyndrickx, W.; Occhipinti, G.; Jensen, V. R.Chem. Eur. J.,201420, 7962-7978.

4.      Automated design of realistic organometallic molecules from fragments.

Foscato, M.; Occhipinti, G.; Venkatraman, V.; Alsberg, B. K.; Jensen, V. R.J. Chem. Inf. Model. 2014, 54, 767-780.

5.      The Complete Reaction Pathway of Ruthenium-Catalyzed Olefin Metathesis of Ethyl Vinyl Ether: Kinetics and Mechanistic Insight from DFT.
Minenkov, Y.; Occhipinti, G.; Jensen, V. R.Organometallics, 2013, 32,2099-2111.

6.      Simple and Highly Z-Selective Ruthenium-Based Olefin Metathesis Catalyst.
Occhipinti, G.; Hansen, F.; Törnroos, K. W.; Jensen. V. R.J. Am. Chem. Soc., 2013, 135, 3331−3334.

7.      Striking a Compromise: Polar Functional Group Tolerance versus Insertion Barrier Height for Olefin Polymerization Catalysts.
Heyndrickx, W.; Occhipinti, G.; Bultinck, P.; Jensen, V. R.Organometallics, 2012, 31, 6022−6031.

8.      An Evolutionary Algorithm for de Novo Optimization of Functional Transition Metal Compounds.
Chu, Y.; Heyndrickx, W.; Occhipinti, G.; Jensen, V. R.; Alsberg, B. K. J. Am. Chem. Soc., 2012, 134, 8885−8895.

9.      The accuracy of DFT-optimized geometries of functional transition metal compounds: A validation study of catalysts for olefin metathesis and other reactions in the homogeneous phase.
Minenkov, Y.; Singstad, Å.; Occhipinti, G.; Jensen, V. R. Dalton Trans., 2012, 41, 5526-5541.  

10.  Nature of the Barrier to Phosphine Dissociation from Grubbs Olefin Metathesis Catalysts.
Minenkov, Y.; Occhipinti, G.; Heyndrickx, W.; Jensen, V. R. Eur. J. Inorg. Chem., 2012, 1507-1516.

11.  Neutral Nickel Oligo- and Polymerization Catalysts: The Importance of Alkyl Phosphine Intermediates in Chain Termination.
Heyndrickx, W.; Occhipinti, G.; Minenkov, Y.; Jensen, V. R.Chem. Eur. J.,2011, 17,14628-14642.

12.  The Nature of the Transition Metal—Alkylidene Bond in Grubbs Catalysts for Olefin Metathesis.
Occhipinti, G.; Jensen, V.R., Organometallics, 2011, 30, 3322-3529.

13.  Synthesis and Stability of Homoleptic Metal(III) Tetramethylaluminates.
Occhipinti, G.; Meermann, C.; Dietrich, M. H.; Litlabø, R.; Auras, F.; Karl W. Törnroos, K. W.;  Maichle-Mössmer, C.; Jensen, V. R.; Anwander, R. J. Am. Chem. Soc. 2011, 133, 6323-6337.

14.  A Switchable Oxidation Process Leading to Two Various Versatile Pharmaceutical
Intermediates
.
Occhipinti, G.; Liguori, L.; Tsoukala, A.; Bjørsvik, H.-R.Org. Process. Res. Dev.,2010, 14, 1387-1392.

15.  On the Nature of the Active Site in Ruthenium Olefin Coordination-Insertion Polymerization Catalysts.
Heyndrickx, W.; Occhipinti, G.; Minenkov, Y.; Jensen, V. R.J. Mol. Cat. A: Chem,2010,324, 64-74.

16.  Metal–Ligand Bond Strengths of the Transition Metals. A Challenge for DFT.
Minenkov, Y.; Occhipinti, G.; Jensen, V. R. J. Phys. Chem. A, 2009, 113, 11833-11844.

17.  Synthesis of a New Bidentate NHC Ag(I) Complex and its Unanticipated Reaction with the Hoveyda-Grubbs First Generation Catalyst.
Occhipinti, G., Jensen, V. R.; Törnroos, K. W.; Frøystein, N. Å.; Bjørsvik, H.-R.Tetrahedron, 2009, 113, 7186-7194.

18.  A Novel Simple and Efficient Bromination Protocol for Activated Arenes.
Tsoukala, A.; Liguori, L.; Occhipinti, G.; Bjorsvik, H.-R. Tetrahedron Letters, 2009, 50, 831-833.

19.  Ruthenium Alkylidene Complexes of Chelating Amine Ligands.
Occhipinti, G.; Bjørsvik, H.-R.; Törnroos, H.-R.; Jensen, V. R.Organometallics, 2007, 26, 5803-5814.

20.  The First Imidazolium-Substituted Metal Alkylidene.
Occhipinti, G.; Bjørsvik, H.-R.; Törnroos, K. W.; Fürstner, A.; Jensen, V. R. Organometallics, 2007, 26, 4383-4385.

21.  Green and Efficient Synthesis of Bidentate Schiff Base Ru Catalysts for Olefin Metathesis.
Occhipinti, G.; Jensen, V. R.; Bjørsvik, H.-R. J. Org. Chem., 2007, 72, 3561–3564.

22.  Quantitative Structure–Activity Relationships of Ruthenium Catalysts for Olefin Metathesis.
Occhipinti, G.; Bjørsvik, H.-R.; Jensen, V. R. J. Am. Chem. Soc. 2006, 128, 6952–6964.

23.  Synthesis of Methoxy-Substituted Phenols by Peracid Oxidation of the Aromatic Ring.
Bjørsvik, H.-R.; Occhipinti, G.; Gambarotti, C.; Cerasino, L.; Jensen, V. R. J. Org. Chem. 2005, 70, 7290-7296.

 

Patents

1.      Jensen, V. R.; Occhipinti, G. Ruthenium and Osmium Heterocyclic Carbene Metathesis Catalysts. Eur. Pat. Appl. EP 2826783 A1 20150121, 2015; U.S. Pat. Appl. Publ. US 2015025212, 2015; Chin. Pat. Appl. CN 104292273 A 20150121, 2015.

2.      Jensen, V. R.; Occhipinti, G. ; Hansen, F. Novel Olefin Metathesis Catalysts. Int. Patent Appl. WO 2012032131, 2012.

 

PhD thesis

Giovanni Occhipinti.
Theory-Assisted Prediction and Synthesis of Ruthenium Alkylidene Complexes for Olefin Metathesis.
Department of Chemistry, University of Bergen, June 2007. ISBN: 9788230804025.