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Jon Andrew Hardie

Professor
  • E-mailJon.Hardie@uib.no
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Husebø, Gunnar; Nielsen, Rune; Hardie, Jon Andrew; Bakke, Per S.; Lerner, Lorena; D'Alessandro-Gabazza, Corina; Gyuris, Jeno; Gabazza, Esteban; Aukrust, Pål; Eagan, Tomas Mikal. 2019. Risk factors for lung cancer in COPD - results from the Bergen COPD cohort study. Respiratory Medicine. 81-88.
  • Le, Lan Ai Kieu; Johannessen, Ane; Hardie, Jon Andrew; Johansen, Odd Erik; Gulsvik, Amund; Vikse, Bjørn Egil; Bakke, Per S. 2019. Prevalence and prognostic ability of the GOLD 2017 classification compared to the GOLD 2011 classification in a Norwegian COPD cohort. The International Journal of Chronic Obstructive Pulmonary Disease. 1639-1655.
  • Aalstad, Linn Tharaldsen; Hardie, Jon Andrew; Espehaug, Birgitte; Thorsen, Einar; Bakke, Per S.; Eagan, Tomas Mikal; Frisk, Bente. 2018. Lung hyperinflation and functional exercise capacity in patients with COPD - a three-year longitudinal study. BMC Pulmonary Medicine. 9 pages.
  • Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L.; Dellacà, Raffaele; Eagan, Tomas Mikal; Bakke, Per S.; Hardie, Jon Andrew. 2017. The association of tidal EFL with exercise performance, exacerbations, and death in COPD. The International Journal of Chronic Obstructive Pulmonary Disease. 2179-2188.
  • Conrad, Douglas J.; Bailey, Barbara A.; Hardie, Jon Andrew; Bakke, Per S.; Eagan, Tomas Mikal; Aarli, Bernt Bøgvald. 2017. Median regression spline modeling of longitudinal FEV1 measurements in cystic fibrosis (CF) and chronic obstructive pulmonary disease (COPD) patients. PLOS ONE. 1-13.
  • Husebø, Gunnar; Grønseth, Rune; Lerner, Lorena; Gyuris, Jeno; Hardie, Jon Andrew; Bakke, Per S.; Eagan, Tomas Mikal. 2017. Growth differentiation factor-15 is a predictor of important disease outcomes in patients with COPD. European Respiratory Journal. 1-10.
  • Persson, Louise Jeanette Pauline; Aanerud, Marianne; Hardie, Jon Andrew; Nilsen, Roy Miodini; Bakke, Per S.; Eagan, Tomas Mikal; Hiemstra, Pieter S. 2017. Antimicrobial peptide levels are linked to airway inflammation, bacterial colonisation and exacerbations in chronic obstructive pulmonary disease. European Respiratory Journal. 1-12.
  • Eagan, Tomas Mikal; Hardie, Jon Andrew; Jul-Larsen, Åsne; Grydeland, Thomas Blix; Bakke, Per S.; Cox, Rebecca Jane. 2016. Self-reported influenza vaccination and protective serum antibody titers in a cohort of COPD patients. Respiratory Medicine. 53-59.
  • Wåtevik, Marie Johanne; Johannessen, Ane; Gomez Real, Francisco; Aanerud, Marianne; Hardie, Jon Andrew; Bakke, Per S.; Eagan, Tomas Mikal. 2016. Oxygen desaturation in 6-min walk test is a risk factor for adverse outcomes in COPD patients. European Respiratory Journal. 82-91.
  • Husebø, Gunnar; Bakke, Per S.; Grønseth, Rune; Hardie, Jon Andrew; Ueland, Thor; Aukrust, Pål; Eagan, Tomas Mikal. 2016. Macrophage migration inhibitory factor, a role in COPD. American Journal of Physiology - Lung cellular and Molecular Physiology. L1-L7.
  • Roth, Kjetil; Eagan, Tomas Mikal; Hardie, Jon Andrew. 2016. Expert opinion of mediastinal lymph node positions from an intrabronchial view. BMC Pulmonary Medicine.
  • Saure, Eirunn Waatevik; Bakke, Per S.; Eagan, Tomas Mikal; Aanerud, Marianne; Jensen, Robert Leroy; Grydeland, Thomas Blix; Johannessen, Ane; Nilsen, Roy Miodini; Thorsen, Einar; Hardie, Jon Andrew. 2016. Diffusion capacity and CT measures of emphysema and airway wall thickness – relation to arterial oxygen tension in COPD patients. European Clinical Respiratory Journal.
  • Persson, Louise Jeanette Pauline; Aanerud, Marianne; Hiemstra, Pieter Sicco; Michelsen, Annika; Ueland, Thor; Hardie, Jon Andrew; Aukrust, Pål; Bakke, Per S.; Eagan, Tomas Mikal. 2015. Vitamin D, vitamin D binding protein, and longitudinal outcomes in COPD. PLOS ONE.
  • Aarli, Bernt Bøgvald; Calverley, Peter M.A.; Jensen, Robert L.; Eagan, Tomas Mikal; Bakke, Per S.; Hardie, Jon Andrew. 2015. Variability of within-breath reactance in COPD patients and its association with dyspnoea. European Respiratory Journal. 625-634.
  • Aanerud, Marianne; Saure, Eirunn Waatevik; Benet, Marta; Basagana, Xavier; Bakke, Per S.; Garcia-Aymerich, Judith; Eagan, Tomas Mikal; Anto, Josep Maria; Hardie, Jon Andrew. 2015. Serial measurements of arterial oxygen tension are associated with mortality in COPD. COPD: Journal of Chronic Obstructive Pulmonary Disease. 287-294.
  • Frisk, Bente; Hardie, Jon Andrew; Espehaug, Birgitte; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2015. Peak oxygen uptake and breathing pattern in COPD patients - a four-year longitudinal study. BMC Pulmonary Medicine.
  • Holmedahl, Nils Henrik; Øverland, Britt; Fondenes, Ove; Ellingsen, Ivar; Hardie, Jon Andrew. 2015. Alcohol at bedtime induces minor changes in sleep stages and blood gases in stable chronic obstructive pulmonary disease. Sleep and Breathing. 307-314.
  • Holmedahl, Nils Henrik; Øverland, Britt; Fondenes, Ove; Ellingsen, Ivar; Hardie, Jon Andrew. 2014. Zopiclone effects on breathing at sleep in stable chronic obstructive pulmonary disease. Sleep and Breathing. 921-930.
  • Holmedahl, Nils Henrik; Øverland, Britt; Fondenes, Ove; Ellingsen, Ivar; Hardie, Jon Andrew. 2014. Sleep hypoventilation and daytime hypercapnia in stable chronic obstructive pulmonary disease. The International Journal of Chronic Obstructive Pulmonary Disease. 265-275.
  • Husebø, Gunnar Reksten; Bakke, Per S.; Aanerud, Marianne; Hardie, Jon Andrew; Ueland, Thor; Grønseth, Rune; Persson, Louise Jeanette Pauline; Aukrust, Pål; Eagan, Tomas Mikal. 2014. Predictors of exacerbations in chronic obstructive pulmonary disease - results from the Bergen COPD Cohort Study. PLOS ONE.
  • Grønseth, Rune; Vollmer, William M.; Hardie, Jon Andrew; Ólafsdottir, Inga Sif; Lamprecht, Bernd; Buist, A. Sonia; Gnatiuc, Louisa; Gulsvik, Amund; Johannessen, Ane; Enright, Paul. 2014. Predictors of dyspnoea prevalence: Results from the BOLD study. European Respiratory Journal. 1610-1620.
  • Saure, Eirunn Waatevik; Eagan, Tomas Mikal; Jensen, Robert Leroy; Bakke, Per S.; Johannessen, Ane; Aanerud, Marianne; Nilsen, Roy Miodini; Thorsen, Einar; Hardie, Jon Andrew. 2014. Predictors for PaO2 and hypoxemic respiratory failure in COPD-A three-year follow-up. COPD: Journal of Chronic Obstructive Pulmonary Disease. 531-538.
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Physical activity and longitudinal change in 6-min walk distance in COPD patients. Respiratory Medicine. 86-94.
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Airway obstruction, dynamic hyperinflation, and breathing pattern during incremental exercise in COPD patients. Physiological Reports.
  • Aarli, Bernt Bøgvald; Eagan, Tomas Mikal; Ellingsen, Ivar; Bakke, Per S.; Hardie, Jon Andrew. 2013. Reference values for within-breath pulmonary impedance parameters in asymptomatic elderly. Clinical Respiratory Journal. 245-252.
  • Hynninen, Kia Minna; Pallesen, Ståle; Hardie, Jon Andrew; Eagan, Tomas Mikal; Bjorvatn, Bjørn; Bakke, Per S.; Nordhus, Inger Hilde. 2013. Insomnia symptoms, objectively measured sleep, and disease severity in chronic obstructive pulmonary disease outpatients. Sleep Medicine. 1328-1333.
  • Gjerde, Bjarte; Bakke, Per S.; Ueland, Thor; Hardie, Jon Andrew; Eagan, Tomas Mikal. 2012. The prevalence of undiagnosed renal failure in a cohort of COPD patients in western Norway. Respiratory Medicine. 361-366.
  • Eagan, Tomas Mikal; Gabazza, Esteban C.; D'Alessandro-Gabazza, Corina; Gil-Bernabe, Paloma; Aoki, Shinya; Hardie, Jon Andrew; Bakke, Per S.; Wagner, Peter D. 2012. TNF-alpha is associated with loss of lean body mass only in already cachectic COPD patients. Respiratory Research. 10 pages.
  • Saure, Eirunn Waatevik; Eagan, Tomas Mikal; Jensen, Robert Leroy; Aanerud, Marianne; Aukrust, Pål; Bakke, Per S.; Hardie, Jon Andrew. 2012. Explained variance for blood gases in a population with COPD. Clinical Respiratory Journal. 72-80.
  • Waatevik, Marie Johanne; Johannessen, Ane; Hardie, Jon Andrew; Bjordal, Jan Magnus; Aukrust, Pål; Bakke, Per S.; Eagan, Tomas Mikal. 2012. Different COPD disease characteristics are related to different outcomes in the 6-minute walk test. COPD: Journal of Chronic Obstructive Pulmonary Disease. 227-234.
  • Persson, Louise; Aanerud, Marianne; Hiemstra, Pieter Sicco; Hardie, Jon Andrew; Bakke, Per S.; Eagan, Tomas Mikal. 2012. Chronic obstructive pulmonary disease is associated with low levels of vitamin D. PLOS ONE. 8 pages.
  • Johannessen, Ane; Bakke, Per S.; Hardie, Jon Andrew; Eagan, Tomas Mikal. 2012. Association of exposure to environmental tobacco smoke in childhood with chronic obstructive pulmonary disease and respiratory symptoms in adults. Respirology (Carlton South. Print). 499-505.
  • Knudsen, Toril Mørkve; Mørkve, Odd; Mfinanga, Sayoki; Hardie, Jon Andrew. 2011. Predictive equations for spirometric reference values in a healthy adult suburban population in Tanzania. Tanzania Health Research Bulletin. 1-10.
  • Edvardsen, Anne; Akerø, Aina; Hardie, Jon Andrew; Ryg, Morten; Eagan, Tomas Mikal; Skjønsberg, Ole Henning; Bakke, Per S. 2011. High prevalence of respiratory symptoms during air travel in patients with COPD. Respiratory Medicine. 50-56.
  • Roth, Kjetil; Eagan, Tomas Mikal; Andreassen, Alf Henrik; Leh, Friedemann; Hardie, Jon Andrew. 2011. A randomised trial of endobronchial ultrasound guided sampling in peripheral lung lesions. Lung Cancer. 219-225.
  • Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S.; Damås, Jan Kristian; Skorge, Trude Duelien; Hardie, Jon Andrew; Ueland, Thor; Mollnes, Tom Eirik. 2010. Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. Respiratory Medicine. 283-290.
  • Eagan, Tomas Mikal Lind; Ueland, Thor; Wagner, Peter D.; Hardie, Jon Andrew; Mollnes, Tom Eirik; Damås, Jan Kristian; Aukrust, Pål; Bakke, Per S. 2010. Systemic inflammatory markers in chronic obstructive pulmonary disease – results from the Bergen COPD Cohort Study. European Respiratory Journal. 540-548.
  • Eagan, Tomas Mikal Lind; Damås, Jan Kristian; Ueland, Thor; Voll-Aanerud, Marianne; Mollnes, Tom Eirik; Hardie, Jon Andrew; Bakke, Per S.; Aukrust, Pål. 2010. Neutrophil Gelatinase-Associated Lipocalin A Biomarker in COPD. Chest. 888-895.
  • Eagan, Tomas Mikal Lind; Aukrust, Pål; Ueland, Thor; Hardie, Jon Andrew; Johannessen, Ane; Mollnes, Tom Eirik; Damås, Jan Kristian; Bakke, Per S.; Wagner, P.D. 2010. Body composition and plasma levels of inflammatory biomarkers in COPD. European Respiratory Journal. 1027-1033.
  • Eagan, Tomas Mikal Lind; Aukrust, Pål; Bakke, Per S.; Damås, Jan Kristian; Skorge, Trude Duelien; Hardie, Jon Andrew; Ueland, Thor; Mollnes, Tom Eirik. 2009. Systemic mannose-binding lectin is not associated with chronic obstructive pulmonary disease. Respiratory Medicine. 283-290.
  • Roth, Kjetil; Hardie, Jon Andrew; Andreassen, Alf Henrik; Leh, Friedemann; Eagan, Tomas Mikal Lind. 2009. Cost minimization analysis for combinations of sampling techniques in bronchoscopy of endobronchial lesions. Respiratory Medicine. 888-894.
  • Roth, Kjetil; Hardie, Jon Andrew; Andreassen, Alf Henrik; Leh, Friedemann; Eagan, Tomas Mikal Lind. 2008. Predictors of diagnostic yield in bronchoscopy: a retrospective cohort study comparing different combinations of sampling techniques. BMC Pulmonary Medicine.
  • Hardie, Jon Andrew; Vollmer, William M.; Buist, A. Sonia; Bakke, Per; Mørkve, Odd. 2005. Respiratory symptoms and obstructive pulmonary disease in a population aged over 70 years. Respiratory Medicine. 186-195.
  • Hardie, Jon Andrew; Vollmer, William M.; Buist, A. Sonia; Ellingsen, Ivar; Mørkve, Odd. 2004. Reference values for arterial blood gases in the elderly. Chest. 2053-2060.
  • Hardie, Jon Andrew; Bakke, Per; Mørkve, Odd. 2004. Non-response bias in a postal questionnaire survey on respiratory health in the old and very old. Scandinavian Journal of Public Health. 411-417.
  • Hardie, Jon Andrew; Bakke, Per; Mørkve, Odd. 2003. Non-response bias in a postal questionnaire survey on respiratory health in the old and very old. Scandinavian Journal of Public Health. 1-7.
Academic lecture
  • Waatevik, Marie; Eagan, Tomas Mikal; Hardie, Jon Andrew; Bakke, Per S.; Gomez Real, Francisco; Frisk, Bente; Johannessen, Ane. 2017. Repeated desaturation in 6 minute walk test increases risk for mortality in COPD patients.
  • Holmedahl, Nils Henrik; Ellingsen, Ivar; Fondenes, Ove; Hardie, Jon Andrew. 2011. Transcutaneous measurement of pCO2 (ptcCO2): Time delay from change in alveolar pCO2 to first response in ptcCO2.
Reader opinion piece
  • Hardie, Jon Andrew. 2012. FVC, total lung capacity, and the differential association to mortality. Chest. 1354-1354.
  • Roth, Kjetil; Eagan, Tomas Mikal; Hardie, Jon Andrew. 2010. Significance of endobronchial lesion appearance in the diagnostic value of different endoscopic techniques Response. Respiratory Medicine. 1387-1387.
Masters thesis
  • Knudsen, Gerd Toril Mørkve. 2010. Prevalence of Respiratory Symptoms and Chronic Obstructive Pulmonary Disease, and Reference Values for Lung Function Testing in Kinondoni District, Dar Es Salaam, Tanzania.
  • Parajuli, Ranjan. 2009. Awareness and prevalence of acute mountain sickness and prevalence of obstructive airflow limitation among Nepalese porters: A cross-sectional study in Khumbu Valley, Nepal.
  • Monsen, Agnete. 2008. Simplified detection of dynamic hyperinflation in patients with chronic obstructive pulmonary disease. Validity and reproducibility in a clinic relevant context.
  • Markussen, Heidi Øksnes. 2008. Health-related quality of life in patients receiving home mechanical ventilation. Translation, adaptation and validation of the; The Severe Respiratory Insufficiency (SRI) Questionnaire -A specific measure of health-related quality of life in patients receiving home mechanical ventilation.
Doctoral dissertation
  • Aarli, Bernt Bøgvald. 2018. Tidal Expiratory Flow Limitation: A new method for evaluating pulmonary function in elderly and patients with Chronic Obstructive Pulmonary Disease .
  • Saure, Eirunn Waatevik. 2016. Predictors of arterial blood gases in COPD patients.
  • Holmedahl, Nils Henrik. 2015. Assessment of nocturnal versus daytime gas exchange in stable COPD. With emphasis on hypoventilation during spontaneous sleep and in sleep influenced by alcohol or zopiclone.
  • Hardie, Jon Andrew. 2004. Respiratory health and normative values for pulmonary function tests and arterial blood gases in the elderly: a Norwegian general population survey.
Abstract
  • Aalstad, Linn Tharaldsen; Hardie, Jon Andrew; Thorsen, Einar; Espehaug, Birgitte; Bakke, Per S.; Eagan, Tomas Mikal; Frisk, Bente. 2017. Static hyperinflation and decline in functional capacity in COPD patients. European Respiratory Journal.
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2016. Respiratory timing and dynamic hyperinflation during incremental exercise in patients with COPD. European Respiratory Journal.
Poster
  • Frisk, Bente; Hardie, Jon Andrew; Espehaug, Birgitte; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2015. Peak oxygen uptake and breathing pattern in COPD patients – a four year longitudinal study.
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Longitudinal change in peak oxygen uptake in COPD patients .
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Longitudinal change in peak oxygen uptake in COPD patients .
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2014. Dynamic hyperinflation and respiratory timing during incremental exercise in patients with chronic obstructive pulmonary disease .
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2013. Slope and curvature of the relationship between ventilation and tidal volume in COPD patients.
  • Frisk, Bente; Espehaug, Birgitte; Hardie, Jon Andrew; Strand, Liv Inger; Moe-Nilssen, Rolf; Eagan, Tomas Mikal; Bakke, Per S.; Thorsen, Einar. 2012. Predictors for longitudinal change in 6-Minute Walk Distance in COPD patients.
  • Holmedahl, Nils Henrik; Ellingsen, Ivar; Fondenes, Ove; Hardie, Jon Andrew. 2011. Agreement Between Measurement Of Expiratory Flow Limitation (EFL) By Impulse Oscillometry (IOS) And Negative Expiratory Pressure (NEP).
  • Edvardsen, Anne; Akerø, Aina; Eagan, Tomas Mikal Lind; Hardie, Jon Andrew; Ryg, Morten; Bakke, Per S.; Skjønsberg, Ole Henning. 2010. In-flight respiratory symptoms and pre-flight characteristics in patients with COPD.
  • Edvardsen, Anne; Akerø, Aina; Eagan, Tomas Mikal Lind; Ryg, Morten; Hardie, Jon Andrew; Bakke, Per S.; Skjønsberg, Ole Henning. 2010. Air travel habits in patients with COPD.
  • Hardie, Jon Andrew; Buist, A. Sonia; Vollmer, William M; Ellingsen, Ivar; Bakke, Per; Mørkve, Odd. 2002. Risk of over-diagnosis of COPD in asymptomatic elderly never-smokers.

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