Tambudzai Kanhema Jakobsen's picture

Tambudzai Kanhema Jakobsen

Head Engineer
  • E-mailTambudzai.Jakobsen@uib.no
  • Phone+47 55 58 60 04
  • Visitor Address
    Jonas Lies vei 91
    5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen
Academic article
  • Show author(s) (2023). Detection of Arc/Arg3.1 oligomers in rat brain: constitutive and synaptic activity-evoked dimer expression in vivo. Frontiers in Molecular Neuroscience. 16 pages.
  • Show author(s) (2022). Activation-induced chromatin reorganization in neurons depends on HDAC1 activity. Cell reports. 24 pages.
  • Show author(s) (2021). The effect of melatonin on Hippo signaling pathway in dental pulp stem cells. Neurochemistry International.
  • Show author(s) (2020). Arc self‐association and formation of virus‐like capsids are mediated by an N‐terminal helical coil motif. The FEBS Journal.
  • Show author(s) (2017). Dynamic Arc SUMOylation and selective interaction with F-actin-binding protein Drebrin A in LTP consolidation in vivo. Frontiers in Synaptic Neuroscience. 1-|14.
  • Show author(s) (2012). Balancing arc synthesis, mRNA decay, and proteasomal degradation : maximal protein expression triggered by rapid eye movement sleep-like bursts of muscarinic cholinergic receptor stimulation. Journal of Biological Chemistry. 22354-22366.
  • Show author(s) (2008). Signal transducer and activator of transcription 3 is involved in the cardioprotective signalling pathway activated by insulin therapy at reperfusion. Basic Research in Cardiology. 444-453.
  • Show author(s) (2008). Object-place recognition learning triggers rapid induction of plasticity-related immediate early genes and synaptic proteins in the rat dentate gyrus. Neural Plasticity.
  • Show author(s) (2007). Sustained Arc/Arg3.1 synthesis controls long-term potentiation consolidation through regulation of local actin polymerization in the dentate gyrus In vivo. Journal of Neuroscience. 10445-10445.
  • Show author(s) (2006). Dual regulation of translation initiation and peptide chain elongation during BDNF-induced LTP in vivo: evidence for compartment-specific translation control. Journal of Neurochemistry. 1328-1337.
  • Show author(s) (2006). Chronic mild stress inhibits BDNF protein expression and CREB activation in the dentate gyrus but not in the hippocampus proper. Pharmacology, Biochemistry and Behavior. 842-849.
  • Show author(s) (2002). Brain-derived neurotrophic factor triggers transcription-dependent, late phase long-term potentiation in vivo. Journal of Neuroscience. 7453-7461.
Thesis at a second degree level
  • Show author(s) (1999). The association of ribosomal subunits and mRNA with the actin filaments.
Masters thesis
  • Show author(s) (2022). Study the mRNA which crisscross with Activity-Regulated Cytoskeleton-Associated Protein (Arc) in the nucleus of hippocampus tissue post HFS-LTP.
  • Show author(s) (2020). Investigation of Arc interaction with mRNA in the nucleus of SH-SY5Y Neuroblastoma cells.
Doctoral dissertation
  • Show author(s) (2007). LTP mechanisms in the dentate gyrus in vivo: BDNF signaling, translation control, and gene function.
  • Show author(s) (2006). p38 MAPK appears to be involved in the cytoprotective effect of insulin therapy administrated at reperfusion. Journal of Molecular and Cellular Cardiology. 973-973.
  • Show author(s) (2006). Insulin therapy appears to involve PKC and NFkB signaling when administered at reperfusion. Journal of Molecular and Cellular Cardiology. 972-973.
  • Show author(s) (2005). Sleep deprivation changes proteome expression. Sleep. A153-A153.
  • Show author(s) (2005). Chronic mild stress, an animal model of depression, affects the expression of BDNF and 5-HT levels over the sleep/wake cycle in hippocampus in rats. Sleep.
  • Show author(s) (2003). BDNF-LTP requires Arc protein expression in rat dentate gyrus in vivo.
  • Show author(s) (2003). BDNF, translation control and dendritic protein synthesis in adult synaptic plasticity.
  • Show author(s) (2002). BDNF triggers transcription-dependent, late phase LTP in vivo.
  • Show author(s) (2001). BDNF-induced long-term potentiation in the dentate gyrus in vivo is associated with phosphorylation of elongation factor-2.
  • Show author(s) (2001). BDNF-induced long-term potentiation in the dentate gyrus in vivo is associated with phosphorylation of elongation factor-2.

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