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University of Bergen
Pediatric Follow-up Group

Inducible laryngeal obstruction and sports

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PhD dissertations

Peer review publications

  1. Leong P, Hull JH, Gibson PG, Halvorsen T, Bardin PG; VCD/ILO Delphi Steering Committee. Reply. J Allergy Clin Immunol. 2023 Sep 20:S0091-6749(23)01111-9. doi: 10.1016/j.jaci.2023.08.027. Epub ahead of print. PMID: 37737751.
  2. Leong P, Vertigan AE, Hew M, Baxter M, Phyland D, Hull JH, Carroll TL, Gibson PG, McDonald VM, Halvorsen T, Clemm HH, Vollsæter M, Røksund OD, Bardin PG; Vocal Cord Dysfunction/Inducible Laryngeal Obstruction Delphi Expert Panel. Diagnosis of vocal cord dysfunction/inducible laryngeal obstruction: An International Delphi Consensus Study. J Allergy Clin Immunol. 2023 Oct;152(4):899-906. doi: 10.1016/j.jaci.2023.06.007. Epub 2023 Jun 20. PMID: 37343843.
  3. Rogde ÅJ, Lehmann S, Halvorsen T, Clemm HH, Røksund OD, Hufthammer KO, Kvidaland HK, Vollsæter M, Andersen TM. Prevalence and impact of exercise-induced laryngeal obstruction in asthma: a study protocol for a cross-sectional and longitudinal study. BMJ Open. 2023 Jun 16;13(6):e071159. doi: 10.1136/bmjopen-2022-071159. PMID: 37328176; PMCID: PMC10277068.
  4. Fretheim-Kelly Z, Clemm HSH, Røksund OD, Hilland M, Vollsæter M, Halvorsen T. Translaryngeal Resistance: A Measurement to Assist Decision Making in Upper Airway Pathology. Am J Respir Crit Care Med. 2023 Sep 15;208(6):e32-e34. doi: 10.1164/rccm.202205-0961IM. PMID: 37219897.
  5. Bernhardsen GP, Stang J, Halvorsen T, Stensrud T. Differences in lung function, bronchial hyperresponsiveness and respiratory health between elite athletes competing in different sports. Eur J Sport Sci. 2023 Aug;23(8):1480-1489. doi: 10.1080/17461391.2022.2113144. Epub 2022 Aug 31. PMID: 35975407.
  6. Clemm HSH. Letter from Norway. Respirology. 2023 May;28(5):500-501. doi: 10.1111/resp.14478. Epub 2023 Mar 7. PMID: 36882379.
  7. Muralitharan P, Carlsen P, Hilland M, Delestre-Levai I, Vollsæter M, Hufthammer KO, Engan M, Røksund OD, Halvorsen T, Clemm HH. Use of inhaled ipratropium bromide to improve exercise-induced laryngeal obstruction cannot be recommended. ERJ Open Res. 2023 Jan 23;9(1):00308-2022. doi: 10.1183/23120541.00308-2022. PMID: 36699648; PMCID: PMC9868967.
  8. Kvidaland H, Stadheim S, Bø S, Clemm H, Røksund OD, Vollsæter M, Hardie J. Is it feasible to perform a continuous laryngoscopy exercise test with a cold air inhalate? A case report. ERJ Open Res. 2022 Nov 28;8(4):00222-2022. doi: 10.1183/23120541.00222-2022. PMID: 36451846; PMCID: PMC9703141.
  9. Gundersen H, Riiser A, Algroy E, Vestbøstad M, Saeterbakken AH, Clemm HH, Grendstad H, Hafstad A, Kristoffersen M, Rygh CB. Associations between biological maturity level, match locomotion, and physical capacities in youth male soccer players. Scand J Med Sci Sports. 2022 Nov;32(11):1592-1601. doi: 10.1111/sms.14225. Epub 2022 Aug 30. PMID: 36004501; PMCID: PMC9804799.
  10. Andersen TM, Vollsæter M. Go With the Flow: Are We Cracking the Code? Respiratory Management of Bulbar ALS Is Evolving. Respir Care. 2022 Oct;67(10):1363-1365. doi: 10.4187/respcare.10487. PMID: 36137578.
  11. Schwellnus M, Adami PE, Bougault V, Budgett R, Clemm HH, Derman W, Erdener U, Fitch K, Hull JH, McIntosh C, Meyer T, Pedersen L, Pyne DB, Reier-Nilsen T, Schobersberger W, Schumacher YO, Sewry N, Soligard T, Valtonen M, Webborn N, Engebretsen L. International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 1: acute respiratory infections. Br J Sports Med. 2022 Jul 21:bjsports-2022-105759. doi: 10.1136/bjsports-2022-105759. Epub ahead of print. PMID: 35863871.
  12. Clemm HH, Olin JT, McIntosh C, Schwellnus M, Sewry N, Hull JH, Halvorsen T. Exercise-induced laryngeal obstruction (EILO) in athletes: a narrative review by a subgroup of the IOC Consensus on 'acute respiratory illness in the athlete'. Br J Sports Med. 2022 Jun;56(11):622-629. doi: 10.1136/bjsports-2021-104704. Epub 2022 Feb 22. PMID: 35193856; PMCID: PMC9120388
  13. Schwellnus M, Adami PE, Bougault V, Budgett R, Clemm HH, Derman W, Erdener U, Fitch K, Hull JH, McIntosh C, Meyer T, Pedersen L, Pyne DB, Reier-Nilsen T, Schobersberger W, Schumacher YO, Sewry N, Soligard T, Valtonen M, Webborn N, Engebretsen L. International Olympic Committee (IOC) consensus statement on acute respiratory illness in athletes part 2: non-infective acute respiratory illness. Br J Sports Med. 2022 May 27:bjsports-2022-105567. doi: 10.1136/bjsports-2022-105567. Epub ahead of print. PMID: 35623888.
  14. Brekka AK, Vollsæter M, Ntoumenopoulos G, Clemm HH, Halvorsen T, Røksund OD, Andersen TM. Adjustments of non-invasive ventilation and mechanically assisted cough by combining ultrasound imaging of the larynx with transnasal fibre-optic laryngoscopy: a protocol for an experimental study. BMJ Open. 2022 May 25;12(5):e059234. doi: 10.1136/bmjopen-2021-059234. PMID: 35613803; PMCID: PMC9134209.
  15. Andersen T, Fondenes O, Røksund OD, Clemm H, Halvorsen T, Vollsæter M. From bedside to bench - In vivo and in vitro evaluation of mechanically assisted cough treatment in a patient with bulbar Amyotrophic Lateral Sclerosis. Respir Med Case Rep. 2022 Apr 9;37:101649. doi: 10.1016/j.rmcr.2022.101649. PMID: 35480384; PMCID: PMC9035434.
  16. Fretheim-Kelly Z, Engan M, Clemm H, Andersen T, Heimdal JH, Strand E, Halvorsen T, Røksund O, Vollsæter M. Reliability of translaryngeal airway resistance measurements during maximal exercise. ERJ Open Res. 2022 Mar 14;8(1):00581-2021. doi: 10.1183/23120541.00581-2021. PMID: 35309036; PMCID: PMC8923134.
  17. Halvorsen T, Røksund O. A novel validated tool to score symptom burden in exercise-induced laryngeal obstruction: can we simplify patient follow-up and research? Lancet Respir Med. 2022 Feb;10(2):131-132. doi: 10.1016/S2213-2600(22)00019-4. PMID: 35120607.
  18. Clemm H, Røksund OD, Andersen T, Heimdal JH, Karlsen T, Hilland M, Fretheim-Kelly Z, Hufthammer KO, Sandnes A, Hjelle S, Vollsæter M, Halvorsen T; Bergen ILO-group. Exercise-induced Laryngeal Obstruction: Protocol for a Randomized Controlled Treatment Trial. Front Pediatr. 2022 Feb 7;10:817003. doi: 10.3389/fped.2022.817003. PMID: 35198517; PMCID: PMC8858975.
  19. Olin JT, Fredericson M, Nichol C, Willick SE, Clemm HH; Tokyo 2020 Isolation Hotel medical support team. Lessons learned from the Tokyo games isolation hotel experience. Br J Sports Med. 2022 Jun;56(11):597-598. doi: 10.1136/bjsports-2021-105116. Epub 2022 Feb 11. PMID: 35149511.
  20. Jansrud Hammer I, Halvorsen T, Vollsaeter M, Hilland M, Heimdal JH, Røksund OD, Clemm HH. Conundrums in the breathless athlete; exercise-induced laryngeal obstruction or asthma? Scand J Med Sci Sports. 2022 Jun;32(6):1041-1049. doi: 10.1111/sms.14137. Epub 2022 Feb 8. PMID: 35114031; PMCID: PMC9303344.
  21. Vollsæter M, Stensrud T, Maat R, Halvorsen T, Røksund OD, Sandnes A, Clemm H. Exercise Related Respiratory Problems in the Young-Is It Exercise-Induced Bronchoconstriction or Laryngeal Obstruction? Front Pediatr. 2022 Jan 3;9:800073. doi: 10.3389/fped.2021.800073. PMID: 35047465; PMCID: PMC8762363.
  22. Sandnes A, Andersen T, Clemm HH, Hilland M, Heimdal JH, Halvorsen T, Røksund OD, Vollsæter M. Clinical responses following inspiratory muscle training in exercise-induced laryngeal obstruction. Eur Arch Otorhinolaryngol. 2022 May;279(5):2511-2522. doi: 10.1007/s00405-021-07214-5. Epub 2021 Dec 26. PMID: 34954812; PMCID: PMC8986676.
  23. Hammer S, Toussaint M, Vollsæter M, Nesbjørg Tvedt M, Drange Røksund O, Reychler G, Lund H, Andersen T. Exercise Training in Duchenne Muscular Dystrophy: A Systematic Review and Meta-Analysis. J Rehabil Med. 2022 Jan 11;54:jrm00250. doi: 10.2340/jrm.v53.985. PMID: 35642324; PMCID: PMC8862644.
  24. Lie AH, Grønnevik I, Frisk B, Røksund OD, Hammer I, Vollsaeter M, Halvorsen T, Clemm HH. Breathing patterns in people with exercise-induced laryngeal obstruction. Physiol Rep. 2021 Nov;9(22):e15086. doi: 10.14814/phy2.15086. PMID: 34822227; PMCID: PMC8613803.
  25. Benestad MR, Drageset J, Clemm H, Røksund OD, Vollsæter M, Halvorsen T, Hysing M, Vederhus BJ. Self-Reported Health in Adolescents With Exercise-Induced Laryngeal Obstruction; A Cross-Sectional Study. Front Pediatr. 2021 Jul 8;9:617759. doi: 10.3389/fped.2021.617759. PMID: 34307244; PMCID: PMC8295467.
  26. McIntosh C, Clemm HH, Sewry N, Hrubos-Strøm H, Schwellnus MP. Diagnosis and management of nasal obstruction in the athlete. A narrative review by subgroup B of the IOC Consensus Group on "Acute Respiratory Illness in the Athlete". J Sports Med Phys Fitness. 2021 Aug;61(8):1144-1158. doi: 10.23736/S0022-4707.21.12821-X. Epub 2021 Jun 22. PMID: 34156184.
  27. Engan M, Hammer IJ, Bekken M, Halvorsen T, Fretheim-Kelly ZL, Vollsæter M, Bovim LPV, Røksund OD, Clemm H. Reliability of maximum oxygen uptake in cardiopulmonary exercise testing with continuous laryngoscopy. ERJ Open Res. 2021 Feb 15;7(1):00825-2020. doi: 10.1183/23120541.00825-2020. PMID: 33614778; PMCID: PMC7882785.
  28. Engan M, Hammer IJ, Stensrud T, Gundersen H, Edvardsen E, Clemm HH. Changes in pulmonary function and feasibility of portable continuous laryngoscopy during maximal uphill running. BMJ Open Sport Exerc Med. 2020 Aug 24;6(1):e000815. doi: 10.1136/bmjsem-2020-000815. PMID: 33403123; PMCID: PMC7772557.
  29. Halvorsen T, Clemm HSH, Vollsæter M, Røksund OD. Conundrums of Exercise-related Breathing Problems. Epiglottic, Laryngeal, or Bronchial Obstruction? Am J Respir Crit Care Med. 2020 Nov 15;202(10):e142-e143. doi: 10.1164/rccm.201910-1921IM. PMID: 32783778.
  30. Fretheim-Kelly Z, Halvorsen T, Heimdal JH, Strand E, Vollsaeter M, Clemm H, Roksund O. Feasibility and tolerability of measuring translaryngeal pressure during exercise. Laryngoscope. 2019 Dec;129(12):2748-2753. doi: 10.1002/lary.27846. Epub 2019 Jan 30. PMID: 30698834; PMCID: PMC6900056.
  31. Fretheim-Kelly ZL, Halvorsen T, Clemm H, Roksund O, Heimdal JH, Vollsæter M, Fintl C, Strand E. Exercise Induced Laryngeal Obstruction in Humans and Equines. A Comparative Review. Front Physiol. 2019 Oct 30;10:1333. doi: 10.3389/fphys.2019.01333. PMID: 31736771; PMCID: PMC6831747.
  32. Sandnes A, Hilland M, Vollsæter M, Andersen T, Engesæter IØ, Sandvik L, Heimdal JH, Halvorsen T, Eide GE, Røksund OD, Clemm HH. Severe Exercise-Induced Laryngeal Obstruction Treated With Supraglottoplasty. Front Surg. 2019 Jul 31;6:44. doi: 10.3389/fsurg.2019.00044. PMID: 31417908; PMCID: PMC6684966.
  33. Andersen TM, Halvorsen T, Fondenes O, Heimdal JH, Røksund OD, Vollsæter M, Røksund OD. Larynx: The Complex Gateway to the Lungs. Respir Care. 2019 Jul;64(7):866-869. doi: 10.4187/respcare.06989. PMID: 31243162.
  34. Sandnes A, Andersen T, Clemm HH, Hilland M, Vollsæter M, Heimdal JH, Eide GE, Halvorsen T, Røksund OD. Exercise-induced laryngeal obstruction in athletes treated with inspiratory muscle training. BMJ Open Sport Exerc Med. 2019 Jan 18;5(1):e000436. doi: 10.1136/bmjsem-2018-000436. PMID: 30792880; PMCID: PMC6350751.
  35. Kolnes LJ, Vollsæter M, Røksund OD, Stensrud T. Physiotherapy improves symptoms of exercise-induced laryngeal obstruction in young elite athletes: a case series. BMJ Open Sport Exerc Med. 2019 Jan 23;5(1):e000487. doi: 10.1136/bmjsem-2018-000487. PMID: 30740235; PMCID: PMC6347884.
  36. Andersen TM, Sandnes A, Fondenes O, Clemm H, Halvorsen T, Nilsen RM, Tysnes OB, Heimdal JH, Vollsæter M, Røksund OD. Laryngoscopy Can Be a Valuable Tool for Unexpected Therapeutic Response in Noninvasive Respiratory Interventions. Respir Care. 2018 Nov;63(11):1459-1461. doi: 10.4187/respcare.06674. PMID: 30389835.
  37. Engeseth MS, Olsen NR, Maeland S, Halvorsen T, Goode A, Røksund OD. Left vocal cord paralysis after patent ductus arteriosus ligation: A systematic review. Paediatr Respir Rev. 2018 Jun;27:74-85. doi: 10.1016/j.prrv.2017.11.001. Epub 2017 Nov 15. PMID: 29336933.
  38. Røksund OD, Olin JT, Halvorsen T. Working Towards a Common Transatlantic Approach for Evaluation of Exercise-Induced Laryngeal Obstruction. Immunol Allergy Clin North Am. 2018 May;38(2):281-292. doi: 10.1016/j.iac.2018.01.002. Epub 2018 Feb 19. PMID: 29631736.
  39. Andersen TM, Sandnes A, Fondenes O, Nilsen RM, Tysnes OB, Heimdal JH, Clemm HH, Halvorsen T, Vollsæter M, Røksund OD. Laryngeal Responses to Mechanically Assisted Cough in Progressing Amyotrophic Lateral Sclerosis. Respir Care. 2018 May;63(5):538-549. doi: 10.4187/respcare.05924. Epub 2018 Apr 17. PMID: 29666294.
  40. Clemm HSH, Sandnes A, Vollsæter M, Hilland M, Heimdal JH, Røksund OD, Halvorsen T. The Heterogeneity of Exercise-induced Laryngeal Obstruction. Am J Respir Crit Care Med. 2018 Apr 15;197(8):1068-1069. doi: 10.1164/rccm.201708-1646IM. PMID: 29390192.
  41. Halvorsen T, Walsted ES, Bucca C, Bush A, Cantarella G, Friedrich G, Herth FJF, Hull JH, Jung H, Maat R, Nordang L, Remacle M, Rasmussen N, Wilson JA, Heimdal JH. Inducible laryngeal obstruction: an official joint European Respiratory Society and European Laryngological Society statement. Eur Respir J. 2017 Sep 9;50(3):1602221. doi: 10.1183/13993003.02221-2016. PMID: 28889105.
  42. Andersen T, Sandnes A, Brekka AK, Hilland M, Clemm H, Fondenes O, Tysnes OB, Heimdal JH, Halvorsen T, Vollsæter M, Røksund OD. Laryngeal response patterns influence the efficacy of mechanical assisted cough in amyotrophic lateral sclerosis. Thorax. 2017 Mar;72(3):221-229. doi: 10.1136/thoraxjnl-2015-207555. Epub 2016 May 12. PMID: 27174631; PMCID: PMC5339574.
  43. Hilland M, Røksund OD, Sandvik L, Haaland Ø, Aarstad HJ, Halvorsen T, Heimdal JH. Congenital laryngomalacia is related to exercise-induced laryngeal obstruction in adolescence. Arch Dis Child. 2016 May;101(5):443-8. doi: 10.1136/archdischild-2015-308450. Epub 2016 Feb 23. PMID: 26906070; PMCID: PMC4853585.
  44. Norlander K, Christensen PM, Maat RC, Halvorsen T, Heimdal JH, Morén S, Rasmussen N, Nordang L. Comparison between two assessment methods for exercise-induced laryngeal obstructions. Eur Arch Otorhinolaryngol. 2016 Feb;273(2):425-30. doi: 10.1007/s00405-015-3758-7. Epub 2015 Sep 8. PMID: 26351037.
  45. Røksund OD, Heimdal JH, Clemm H, Vollsæter M, Halvorsen T. Exercise inducible laryngeal obstruction: diagnostics and management. Paediatr Respir Rev. 2017 Jan;21:86-94. doi: 10.1016/j.prrv.2016.07.003. Epub 2016 Jul 18. PMID: 27492717.
  46. Christensen PM, Heimdal JH, Christopher KL, Bucca C, Cantarella G, Friedrich G, Halvorsen T, Herth F, Jung H, Morris MJ, Remacle M, Rasmussen N, Wilson JA; ERS/ELS/ACCP Task Force on Inducible Laryngeal Obstructions. ERS/ELS/ACCP 2013 international consensus conference nomenclature on inducible laryngeal obstructions. Eur Respir Rev. 2015 Sep;24(137):445-50. doi: 10.1183/16000617.00006513. PMID: 26324806; PMCID: PMC9487687.
  47. Røksund OD, Heimdal JH, Olofsson J, Maat RC, Halvorsen T. Larynx during exercise: the unexplored bottleneck of the airways. Eur Arch Otorhinolaryngol. 2015 Sep;272(9):2101-9. doi: 10.1007/s00405-014-3159-3. Epub 2014 Jul 18. PMID: 25033930; PMCID: PMC4526593.
  48. Andersen T, Sandnes A, Hilland M, Halvorsen T, Fondenes O, Heimdal JH, Tysnes OB, Røksund OD. Laryngeal response patterns to mechanical insufflation-exsufflation in healthy subjects. Am J Phys Med Rehabil. 2013 Oct;92(10):920-9. doi: 10.1097/PHM.0b013e3182a4708f. PMID: 24051994.
  49. Sandnes A, Andersen T, Hilland M, Ellingsen TA, Halvorsen T, Heimdal JH, Røksund OD. Laryngeal movements during inspiratory muscle training in healthy subjects. J Voice. 2013 Jul;27(4):448-53. doi: 10.1016/j.jvoice.2013.02.010. Epub 2013 May 15. PMID: 23683807.
  50. Maat RC, Hilland M, Røksund OD, Halvorsen T, Olofsson J, Aarstad HJ, Heimdal JH. Exercise-induced laryngeal obstruction: natural history and effect of surgical treatment. Eur Arch Otorhinolaryngol. 2011 Oct;268(10):1485-92. doi: 10.1007/s00405-011-1656-1. Epub 2011 Jun 5. PMID: 21643933; PMCID: PMC3166603.
  51. Halvorsen T, Røksund OD, Maat RC, Heimdal JH. In reference to: "Use of post-exercise laryngoscopy to evaluate exercise induced dyspnea" Pediatric Pulmonol, 2010; 45: 1037-1039. Pediatr Pulmonol. 2011 May;46(5):515-6. doi: 10.1002/ppul.21431. Epub 2011 Feb 17. PMID: 21337532.
  52. Røksund OD, Clemm H, Heimdal JH, Aukland SM, Sandvik L, Markestad T, Halvorsen T. Left vocal cord paralysis after extreme preterm birth, a new clinical scenario in adults. Pediatrics. 2010 Dec;126(6):e1569-77. doi: 10.1542/peds.2010-1129. Epub 2010 Nov 22. PMID: 21098147.
  53. Røksund OD, Maat RC, Heimdal JH, Olofsson J, Skadberg BT, Halvorsen T. Exercise induced dyspnea in the young. Larynx as the bottleneck of the airways. Respir Med. 2009 Dec;103(12):1911-8. doi: 10.1016/j.rmed.2009.05.024. Epub 2009 Sep 26. PMID: 19782550.
  54. Maat RC, Røksund OD, Halvorsen T, Skadberg BT, Olofsson J, Ellingsen TA, Aarstad HJ, Heimdal JH. Audiovisual assessment of exercise-induced laryngeal obstruction: reliability and validity of observations. Eur Arch Otorhinolaryngol. 2009 Dec;266(12):1929-36. doi: 10.1007/s00405-009-1030-8. Epub 2009 Jul 8. PMID: 19585139.
  55. Maat RC, Røksund OD, Olofsson J, Halvorsen T, Skadberg BT, Heimdal JH. Surgical treatment of exercise-induced laryngeal dysfunction. Eur Arch Otorhinolaryngol. 2007 Apr;264(4):401-7. doi: 10.1007/s00405-006-0216-6. Epub 2007 Jan 4. PMID: 17203312.
  56. Heimdal JH, Røksund OD, Halvorsen T, Skadberg BT, Olofsson J. Continuous laryngoscopy exercise test: a method for visualizing laryngeal dysfunction during exercise. Laryngoscope. 2006 Jan;116(1):52-7. doi: 10.1097/01.mlg.0000184528.16229.ba. PMID: 16481809.
 

 

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Thomas Halvorsen's picture

Thomas Halvorsen

Professor

Department of Clinical Science

thomas.halvorsen@uib.no

Maria Vollsæter's picture

Maria Vollsæter

Guest Researcher

Department of Clinical Science

maria.vollseter@uib.no

Mette Engan's picture

Mette Engan

Guest Researcher

Department of Clinical Science

mette.engan@uib.no

31.10.2023