ProtMetD: Protein Modifications, Metabolism and Disease

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Forskere ved MBI oppdager viktigheten av vitamin B3

Forskerne Nick Love, Nadine Pollak, Christian Döelle og Mark Niere fra Zieglergruppen har funnet ut at siste stadie i omdannelsen av vitamin B3 til molekylet NADP er avgjørende for den embryoniske utviklingen av dyr.

The enzyme NAD kinase is responsible for the final step in the conversion of vitamin B3 to NADP (used collectively for NADPH and NADP+). NADPH is an important molecule, which connects metabolism and various defence mechanisms. These include the immune response, detoxification reactions and the "fueling" of natural antioxidant systems.

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