Kurt Hanevik
- E-mailKurt.Hanevik@uib.no
- Phone+47 55 97 30 79
- Visitor AddressHaukeland universitetssykehus, Laboratoriebygget5009 Bergen
- Postal AddressPostboks 78045020 Bergen
Medical doctor and specialist in infectious diseases. Interest and experience in international humanitarian aid and global health. PhD research into long term sequels after Giardia infection. Main research interest is into diarrheal diseases and work on Giardia and Cryptosporidium diagnostics, epidemiology and immunology, as well as a human ETEC challenge model and characterization of human immune responses against ETEC.
December 2020: Near-patient testing for neglected diarrheal disease in resource-limited countries - MedicalXpress
January 2019: Giardiasis Linked With Prolonged Alteration of Lymphocytes in Duodenal Mucosa, Clinical Advisor
Februar 2018: De lar seg frivillig smitte med E.coli - Nettsak NRK
Februar 2018: Menneskemodell for testing av ETEC vaksine - NRK dagsrevyen 21
November 2017: Studenter pådro seg diare frivillig - StudVest
August 2014: Giardia infections related to IBS, fatigue 6 years later – Healio Infectious Disease News
August 2014: Giardia infection may lead to persistent IBS, chronic fatigue – Healthy Living magazine
August 2014: Halvparten av Giardia-syke plages seks år etter - Bergens Tidende
Januar 2012: PhD grad - pressemelding
Januar 2012: Giardia parasitten stresser immunforsvaret - Bergens Tidende
Januar 2008: Fikk kronisk mageinfeksjon etter Giardia-smitte – Aftenposten
Januar 2008: Fekk kronisk mageinfeksjon - NRK-Hordaland
Mars 2007: Giardia-parasitten gav irritabel tarm - Dagens Medisin
Websites: Bergen Giardia Research Group, Norwegian National Advisory Unit on Tropical Infectious Diseases
TPBAMIKR - Microbiology/Immunology for dental assistants - course responsible
OD2MIKR - Microbiology for dentist students - course responsible
VAC901 - Vaccinology - course responsible
MED4 - Microbiology for medical students
FARM270 - Infections & tropical diseases
SYK250 - Malaria & travel medicine for nursing students
SDG303 - Malaria, Neglected diseases
MED11 - Gastroenteritis
GCP901 - Good Clinical Practice
INT304 - War and health
Dnlf-courses in tropical medicine, parasitlogy and infectious diseases
H20&21 5234 Doctoral course Karolinska - Giardia & Cryptosporidium overview
Main publications
Rim S, Sakkestad ST, Zhou F, Gullaksen SE, Skavland J, Chauhan SK, Steinsland H, Hanevik K. Dynamics of circulating lymphocytes responding to human experimental enterotoxigenic Escherichia coli infection. Eur J Immunol. 2023 Apr 27:e2250254
Saghaug CS, Gamlem AL, Hauge KB, Vahokoski J, Klotz C, Aebischer T, Langeland N, Hanevik K. Genetic diversity in the metronidazole metabolism genes nitroreductases and pyruvate ferredoxin oxidoreductases in susceptible and refractory clinical samples of Giardia lamblia. Int J Parasitol Drugs Drug Resist. 2023 Apr;21:51-60.
Johansen ØH, Abdissa A, Bjørang O, Zangenberg M, Sharew B, Alemu Y, Moyo S, Mekonnen Z, Langeland N, Robertson LJ, Hanevik K. Oocyst Shedding Dynamics in Children with Cryptosporidiosis: a Prospective Clinical Case Series in Ethiopia. Microbiol Spectr. 2022 Aug 31;10(4):e0274121
Johansen ØH, Abdissa A, Zangenberg M, Mekonnen Z, Eshetu B, Bjørang O, Alemu Y, Sharew B, Langeland N, Robertson LJ, Hanevik K. Performance and operational feasibility of two diagnostic tests for cryptosporidiosis in children (CRYPTO-POC): a clinical, prospective, diagnostic accuracy study. Lancet Infect Dis. 2020 Dec 3:S1473-3099(20)30556-9.
Sakkestad ST, Steinsland H, Skrede S, Lillebø K, Skutlaberg DH, Guttormsen AB, Zavialov A, Paavilainen S, Søyland H, Sævik M, Heien AR, Tellevik MG, Barry E, Langeland N, Sommerfelt H, Hanevik K. A new human challenge model for testing heat-stable toxin-based vaccine candidates for enterotoxigenic Escherichia coli diarrhea - dose optimization, clinical outcomes, and CD4+ T cell responses. PLoS Negl Trop Dis. 2019 Oct 30;13(10):e0007823.
Sakkestad ST, Skavland J, Hanevik K. Whole blood preservation methods alter chemokine receptor detection in mass cytometry experiments. J Immunol Methods. 2019 Oct 17:112673
Zangenberg M, Johansen ØH, Abdissa A, Eshetu B, Kurtzhals JAL, Friis H, Sommerfelt H, Langeland N, Hanevik K. Prolonged and persistent diarrhoea is not restricted to children with acute malnutrition: an observational study in Ethiopia. Trop Med Int Health. 2019 Jul 20
Dizdar V, Hausken T, Larum OD, Gilja OH, Langeland N, Hanevik K. Prolonged duodenal mucosal lymphocyte alterations in patients with and without post infectious functional gastrointestinal disorders after Giardia infection. J Infect Dis. 2018 Nov 30
Hanevik K, Kristoffersen E, Mørch K, Rye KP, Sørnes S, Svärd S, Bruserud Ø, Langeland N. Giardia-specific cellular immune responses in post-giardiasis chronic fatigue syndrome. BMC Immunol. 2017 Jan 28;18(1):5.
Hjøllo T, Bratland E, Steinsland H, Radunovic M, Langeland N, Hanevik K. Longitudinal cohort study of serum antibody responses towards Giardia lamblia variant-specific surface proteins in a non-endemic area. Exp Parasitol. 2018 Jun 14.
Saghaug CS, Sørnes S, Peirasmaki D, Svärd S, Langeland N, Hanevik K. Human Memory CD4+ T Cell Immune Responses against Giardia lamblia. Clin Vaccine Immunol. 2015 Sep 16;23(1):11-8.
Tellevik MG, Moyo SJ, Blomberg B, Hjøllo T, Maselle SY, Langeland N, Hanevik K. Prevalence of Cryptosporidium parvum/hominis, Entamoeba histolytica and Giardia lamblia among Young Children with and without Diarrhea in Dar es Salaam, Tanzania. PLoS Negl Trop Dis. 2015 Oct 9;9(10):e0004125.
Hanevik K, Bakken R, Brattbakk HR, Saghaug CS, Langeland N. Whole genome sequencing of clinical isolates of Giardia lamblia. Clin Microbiol Infect. 2015 Feb;21(2):192.e1-3.
Hanevik K, Wensaas KA, Rortveit G, Eide GE, Mørch K, Langeland N. Irritable bowel syndrome and chronic fatigue six years after Giardia infection: a controlled prospective cohort study. Clin Infect Dis. 2014 Nov 15;59(10):1394-400.
Haanshuus CG, Mohn SC, Mørch K, Langeland N, Blomberg B, Hanevik K. A novel, single-amplification PCR targeting mitochondrial genome highly sensitive and specific in diagnosing malaria among returned travellers in Bergen, Norway. Malar J. 2013 Jan 22;12:26.
STRACOL - Bacterial strain colonization in fecal microbiota transfer therapy in patients with irritable bowel syndrome (2023 -> )
COLONIZE - Transplantation of intestinal microbiota in primary Clostridoides difficile infections (2022 - > )
TaDiGe - Detection and prevalence of intestinal parasites in Norway, including genotyping of circulating Giardia and Cryptosporidium variants (2022 -> )
ETECvac - Experimental infection of volunteers with heat-stable toxin (ST)-only producing enterotoxigenic Escherichia coli (ETEC) (2014 -> )
Combined Shigella-ETEC vaccine - in collaboration with prof Eileen Barry at Center for Vaccine development, University of Maryland, Baltimore, USA (2015)
BCGI - An immuological substudy of innate and adaptive immunity within the Early versus late BCG vaccination in HIV-1 exposed infants study - a randomized controlled trial of the effect of deferring BCG vaccination to 14 weeks of age in HIV-1 exposed infants in Uganda - (2017 -> )
Crypto-POC - LED microscopy for Cryptosporidium testing in children in low-income countries (2016 -> )
GSI - Metronidazole resistent Giardia infeksjon og immun responser mot Giardia (2010 -> )
Previous projects
GIFF - Giardia lamblia indusert kronisk fatigue syndrom og funksjonelle mageplager – biomarkører, risikofaktorer og effekt av intervensjon (2008 - 2019)
GENIEUR- pan-Europeisk interdisiplinært nettverk for å identifiserte genetiske faktorer som bidrar til utvikling av irritabel tarm syndrom
Euro-FBP - European Network for Foodborne Parasites