- E-mailOdd.Karlsen@uib.no
- Phone+47 55 58 46 51
- Visitor AddressThormølens gate 53 A/B5006 Bergen
- Postal AddressPostboks 78035020 Bergen
Academic article
- (2022). Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). Science of the Total Environment.
- (2022). Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). Environment International.
- (2021). Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. Polar Biology. 345-358.
- (2021). Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. Toxicology in Vitro. 10 pages.
- (2021). Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. Environmental Toxicology and Pharmacology. 1-10.
- (2021). The chemical defensome of five model teleost fish. Scientific Reports. 1-13.
- (2021). Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology. 15123-15135.
- (2021). Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. Aquatic Toxicology. 1-11.
- (2020). Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua). Aquatic Toxicology. 13 pages.
- (2020). Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology. 1033-1044.
- (2020). Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua). Aquatic Toxicology. 10 pages.
- (2019). Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. Environmental Science and Technology. 7036-7044.
- (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Frontiers in Genetics. 1-18.
- (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. Marine Environmental Research. 39-51.
- (2019). Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. Fish and Shellfish Immunology. 650-658.
- (2018). Sequence variations in pxr (nr1i2) from Zebrafish (Danio rerio) strains affect nuclear receptor function. Toxicological Sciences. 28-39.
- (2018). RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. Aquatic Toxicology. 174-186.
- (2018). LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. Toxicology in Vitro. 332-341.
- (2018). Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports. 1-13.
- (2018). Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. Chemosphere. 328-339.
- (2018). Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. Science of the Total Environment. 1640-1648.
- (2017). Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. Aquatic Toxicology. 19-28.
- (2016). Transcriptomic profiling of Methylococcus capsulatus (Bath)during growth with two different methane monooxygenases. MicrobiologyOpen. 254-267.
- (2016). Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. BMC Genomics. 1-15.
- (2016). Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). Fish and Shellfish Immunology. 9-17.
- (2016). Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays. Marine Pollution Bulletin. 53-61.
- (2014). Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vitro system for studying the effects of environmental contaminants. Aquatic Toxicology. 110-115.
- (2014). Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism. BMC Genomics.
- (2014). CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. PLOS ONE.
- (2014). Alterations in the atlantic COD (Gadus morhua) hepatic thiol-proteome after methylmercury exposure. Journal of Toxicology and Environmental Health, Part A. 650-662.
- (2013). Global transcriptome analysis of Atlantic cod (Gadus morhua) liver after in vivo methylmercury exposure suggests effects on energy metabolism pathways. Aquatic Toxicology. 314-325.
- (2012). The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. PLOS ONE. 10 pages.
- (2012). Mass spectrometric analyses of microsomal cytochrome P450 isozymes isolated from beta-naphthoflavone-treated Atlantic cod (Gadus morhua) liver reveal insights into the cod CYPome. Aquatic Toxicology. 2-10.
- (2012). Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics. BMC Genomics. 17 pages.
- (2011). Integrative Environmental Genomics of Cod (Gadus morhua): The Proteomics Approach. Journal of Toxicology and Environmental Health, Part A. 494-507.
- (2010). Identification of a bacterial di-haem cytochrome c peroxidase from Methylomicrobium album BG8. Microbiology (Reading). 2682-2690.
- (2009). Human Naa50p (Nat5/San) Displays Both Protein N-alpha- and N-epsilon-Acetyltransferase Activity. Journal of Biological Chemistry. 31122-31129.
- (2008). The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper. Molecular Microbiology. 15-26.
- (2008). An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. Journal of Biological Chemistry. 13897-13904.
- (2006). Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. Archives of Microbiology. 362-377.
- (2005). Identification of a copper-repressible cytochrome c peroxidase of Methylococcus capsulatus (Bath); a member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins. The FEBS Journal. 6324-6335.
- (2005). Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). The FEBS Journal. 2428-2440.
- (2004). The core 2 ß-1,6-N-acetylglucosaminyltransferase-M encoded by bovine herpesvirus 4 is not essential for virus replication despite contributing to post-translational modifications of structural proteins. Journal of General Virology. 355-367.
- (2003). The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. Applied and Environmental Microbiology. 2386-2388.
- (2003). Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. Electrophoresis. 757-761.
Report
- (2021). PW-Exposed Final Report: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species (OC2021 A-107). .
Lecture
- (2019). Chemical warfare in the marine environment.
- (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
Academic lecture
- (2021). Genomic responses to pollutants in Arctic fish and copepod species.
- (2020). Polar cod and Goliat: How an oil spill may affect polar cod reproduction.
- (2020). Adapting a liver slice culture method for ex vivo toxicological studies in arctic and sub-arctic fish species during sampling cruises.
- (2020). ANTIESTROGENIC EFFECTS OF BENZO[a]PYRENE REVEALED BY TRANSCRIPTOME ANALYSIS IN POLAR COD LIVER SLICE CULTURE.
- (2020). A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua).
- (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
- (2019). Toxicogenomic responses in Atlantic cod (Gadus morhua) after treatment with selected environmental contaminants in vivo and ex vivo.
- (2019). The chemical defensome of Atlantic cod (Gadus morhua).
- (2019). In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua).
- (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Conference talk.
- (2019). EFFECTS OF SELECTED ENVIRONMENTAL ESTROGENS ON EXPRESSION OF FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY GENES IN THE LIVER OF ATLANTIC COD (GADUS MORHUA) IN VIVO AND EX VIVO.
- (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
- (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
- (2019). Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices.
- (2019). Agricultural pesticides in aquafeeds might harm wild fish feeding on leftover pellets near fish farms.
- (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA).
- (2018). The nuclear receptor complement of Atlantic cod (Gadus morhua) as potential targets for endocrine disrupting compounds.
- (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
- (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
- (2018). Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human.
- (2018). Modelling the chemical defensome network - a dynamic visualisation of the involved genes and pathways in two fish species and humans .
- (2018). Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans.
- (2018). Establishing a cellfree method for xenobiotic detection using ligand activated receptors from the Atlantic cod, Gadus morhua.
- (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
- (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
- (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
- (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
- (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
- (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
- (2018). Agonistic and antagonistic effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
- (2017). PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT.
- (2017). Integrative transcriptome and proteome analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153.
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
- (2017). CHARACTERIZATION OF THE ARYL HYDROCARBON RECEPTORS AHR1B AND AHR2 IN ATLANTIC COD (GADUS MORHUA).
- (2016). Toxicogenomics as a tool for understanding responses to pollutants in organisms: Using Atlantic cod (Gadus morhua) and a systems biology approach to environmental toxicology.
- (2016). Integrative -omics analyses reveal perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) exposed to the persistent organic pollutant PCB 153.
- (2016). Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor.
- (2014). ALTERATIONS IN THE HEPATIC PROTEOME OF POLAR COD (BOREOGADUS SAIDA) AFTER DIETARY EXPOSURE TO BENZO[A]PYRENE.
- (2011). Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.
- (2003). The expression of the surface associated MopE protein of Methylococcus capsulatus (Bath) is regulated by the concentration of copper in the growth medium.
- (2003). Proteome studies on the methanotrophic bacterium Methylococcus capsulatus (Bath).
- (2003). Multiple polypeptide forms observed in twodimensional gels of Methylococcus capsulatus (Bath)polypeptides are generated during the separation procedure.
- (2002). Initial proteome studies of Methylococcus capsulatus (Bath).
Thesis at a second degree level
- (2005). A study of McHr – a novel prokaryotic hemerythrin from Methylococcus capsulatus (Bath).
- (2004). Studies of Methylococcus capsulatus (Bath): The surface associated protein SapE.
- (2001). The proteome of Methylococcus capsulatus; An initial study by two-domentional gel electrophoresis.
Feature article
- (2018). Torsken manglar eit viktig gen i forsvaret mot miljøgifter. Forskning.no.
Doctoral dissertation
- (2019). Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta).
- (2005). Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath).
Abstract
- (2012). Integrative environmental genomics of cod (Gadus morhua) reveal the mechanisms underlying MeHg- and PCB153 induced toxicity. Comparative Biochemistry and Physiology A. S49-S49.
- (2010). iCod: Integrative environmental genomics of cod (Gadus morhua); the proteomics approach. Comparative Biochemistry and Physiology A. S44-S44.
- (2010). The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. The FEBS Journal. 185-185.
- (2010). Human Naa50p (Nat5/San) displays both protein N-alpha- and N-epsilon-Acetyltransferase activity. The FEBS Journal. 182-182.
Poster
- (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene.
- (2021). Development of a battery of Atlantic cod receptor-based reporter bioassays for assessing environmental toxicity of sediments and chemicals.
- (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
- (2019). THE CHEMICAL DEFENSOME OF ATLANTIC COD (GADUS MORHUA): HOW DOES IT DIFFER FROM DEFENSOME NETWORKS IN OTHER TELEOST SPECIES?
- (2019). Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua).
- (2019). In vitro assessment of estrogenic effects of bisphenols on Atlantic cod (Gadus morhua).
- (2019). Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture.
- (2019). Chemical warfare in the aquatic environment - The chemical defensome networks of model fish species.
- (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) .
- (2019). Assessment of produced water toxicity using in vitro tools developed from Atlantic cod (Gadus morhua).
- (2018). PW-Exposed: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species.
- (2018). MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human.
- (2018). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
- (2018). Effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
- (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua).
- (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
- (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
- (2017). dCod 1.0 decoding the systems toxicology of Atlantic cod.
- (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2017). Using precision cut liver slices (PCLS) for studying effects of environmental contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
- (2017). Studying estrogenic effects of environmental pollutants by using the Atlantic cod (Gadus morhua) estrogen receptor α and a reporter gene assay.
- (2017). Peroxisome proliferator-activated receptors (PPARs) as tools for studying effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
- (2017). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
- (2016). Using precision-cut liver slices (PCLS) and luciferase reporter gene assay to characterize the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2016). Systems Toxicology Studies to Investigate Mechanisms of Toxicity of Environmental Chemicals Using Atlantic cod (Gadus morhua) as a Model Organism.
- (2016). Peroxisome proliferator-activated receptors (PPARs) as tools to study effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
- (2016). Integrated analysis of transcriptome and proteome reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with the persistent organic pollutant PCB 153 .
- (2016). Effektar på lipidmetabolismen til atlanterhavstorsk (Gadus morhua) etter eksponering mot enkeltsambindingar og blandingar av miljøgiftar.
- (2014). Alterations in the hepatic proteome of polar cod (Boreogadus saida) after dietary exposure to benzo(a)pyrene .
- (2012). Integrative environmental genomics of Atlantic cod (Gadus morhua): exposure of cod liver slices to environmental contaminants.
- (2010). Human Naa50p (Nat5/San) Displays Both Protein Na-and Ne-Acetyltransferase activity.
- (2004). Surface proteins of M. capsulatus (Bath) possibly involved in copper uptake.
- (2004). Copper-regulation of some surface-exposed and secreted proteins of the methane-oxidizing bacterium Methylococcus capsulatus (Bath).
- (2004). Copper homeostasis in Methylococcus capsulatus.
- (2004). An introduction to copper homeostasis in Methylococcus capsulatus.
- (2003). Identification of the ORF upstream of MopE in Methylococcus capsulatus.
- (2003). Differential expression in sMMO and pMMO producing cells of Methylococcus capsulatus (Bath).
- (2002). Initial proteome studies on Methylococcus capsulatus (Bath).
- (2002). Characterization of copper-repressible extracellular protein of Methylococcus capsulatus (Bath).
Academic literature review
- (2011). The copper responding surfaceome of Methylococccus capsulatus Bath. FEMS Microbiology Letters. 97-104.
- (2011). Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. Methods in Enzymology. 63-79.
- (2011). METHANOTROPH OUTER MEMBRANE PREPARATION. Methods in Enzymology. 167-176.
Article in business/trade/industry journal
- (2022). Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). Science of the Total Environment.
More information in national current research information system (CRIStin)