- E-mailodd.karlsen@uib.no
- Phone+47 55 58 46 51
- Visitor AddressThormøhlens gate 53A/B5006 BergenRoom4H19
- Postal AddressPostboks 78035020 Bergen
My research interests concern the molecular mechanisms and mode of actions underlying the toxicity of environmental pollutants, and how this may manifest across biological organizations and produce higher level effects (organism, population). My research focuses mainly on marine organisms, and central topics within my current research activities include endocrine disruption, nuclear receptors, biomarkers, bioassays, microplastics, integrative genomics/toxicogenomics, chemicals of emerging concern, and cocktail effects.
I am currently leading the University of Bergen’s network for marine plastic pollution (Plastics Network). This network embraces cross-disciplinary research concerning plastic and microplastic pollution in our oceans, encompassing the investigation of the presence, distribution, and effects of plastic pollution, as well as its societal, legal, and health implications.
Responsible for BIO216 Toxicology (course evaluation)
Supervisor in BIO299 Research practise in biology/molecular biology
Lecturer in BIO208 Environmental impact of aquaculture
Lecturer in BIO316 Selected topics in environmental toxicology
Scientific coordinator for the Environmental Toxicology master program at the Department of Biological Sciences
- (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. Marine Genomics. 1-13.
- (2022). Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). Science of the Total Environment.
- (2022). Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). Science of the Total Environment. 17 pages.
- (2022). Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). Environment International. 15 pages.
- (2021). Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. Polar Biology. 345-358.
- (2021). Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. Toxicology in Vitro. 10 pages.
- (2021). Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. Environmental Toxicology and Pharmacology. 1-10.
- (2021). The chemical defensome of five model teleost fish. Scientific Reports. 1-13.
- (2021). Substituted Two- To Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology. 15123-15135.
- (2021). Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. Aquatic Toxicology. 1-11.
- (2020). Proteomics and lipidomics analyses reveal modulation of lipid metabolism by perfluoroalkyl substances in liver of Atlantic cod (Gadus morhua). Aquatic Toxicology. 13 pages.
- (2020). Molecular and Functional Properties of the Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environmental Science and Technology. 1033-1044.
- (2020). Expression and localization of the aryl hydrocarbon receptors and cytochrome P450 1A during early development of Atlantic cod (Gadus morhua). Aquatic Toxicology. 10 pages.
- (2019). Modulation of neuro-dopamine homeostasis in juvenile female Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances. Environmental Science and Technology. 7036-7044.
- (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Frontiers in Genetics. 1-18.
- (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) caged at a capped waste disposal site in Kollevåg, Western Norway. Marine Environmental Research. 39-51.
- (2019). Analysis of immunoglobulin and T cell receptor gene expression in ballan wrasse (Labrus bergylta) revealed an extraordinarily high IgM expression in the gut. Fish and Shellfish Immunology. 650-658.
- (2018). Sequence variations in pxr (nr1i2) from Zebrafish (Danio rerio) strains affect nuclear receptor function. Toxicological Sciences. 28-39.
- (2018). RNA-Seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision-cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol. Aquatic Toxicology. 174-186.
- (2018). LC-MS/MS based profiling and dynamic modelling of the steroidogenesis pathway in adrenocarcinoma H295R cells. Toxicology in Vitro. 332-341.
- (2018). Independent losses of a xenobiotic receptor across teleost evolution. Scientific Reports. 1-13.
- (2018). Effects of defined mixtures of POPs and endocrine disruptors on the steroid metabolome of the human H295R adrenocortical cell line. Chemosphere. 328-339.
- (2018). Assessing the environmental quality of sediments from Split coastal area (Croatia) with a battery of cell-based bioassays. Science of the Total Environment. 1640-1648.
- (2017). Quantitative proteomics analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153. Aquatic Toxicology. 19-28.
- (2016). Transcriptomic profiling of Methylococcus capsulatus (Bath)during growth with two different methane monooxygenases. MicrobiologyOpen. 254-267.
- (2016). Quantitative analyses of the hepatic proteome of methylmercury-exposed Atlantic cod (Gadus morhua) suggest oxidative stress-mediated effects on cellular energy metabolism. BMC Genomics. 1-15.
- (2016). Characterization of IgM in Norwegian cleaner fish (lumpfish and wrasses). Fish and Shellfish Immunology. 9-17.
- (2016). Assessment of the environmental quality of coastal sediments by using a combination of in vitro bioassays. Marine Pollution Bulletin. 53-61.
- (2014). Precision-cut liver slices of Atlantic cod (Gadus morhua): An in vitro system for studying the effects of environmental contaminants. Aquatic Toxicology. 110-115.
- (2014). Liver transcriptome analysis of Atlantic cod (Gadus morhua) exposed to PCB 153 indicates effects on cell cycle regulation and lipid metabolism. BMC Genomics.
- (2014). CorA is a copper repressible surface-associated copper(I)-binding protein produced in Methylomicrobium album BG8. PLOS ONE.
- (2014). Alterations in the atlantic COD (Gadus morhua) hepatic thiol-proteome after methylmercury exposure. Journal of Toxicology and Environmental Health, Part A. 650-662.
- (2013). Global transcriptome analysis of Atlantic cod (Gadus morhua) liver after in vivo methylmercury exposure suggests effects on energy metabolism pathways. Aquatic Toxicology. 314-325.
- (2012). The Methylococcus capsulatus (Bath) Secreted Protein, MopE*, Binds Both Reduced and Oxidized Copper. PLOS ONE. 10 pages.
- (2012). Mass spectrometric analyses of microsomal cytochrome P450 isozymes isolated from beta-naphthoflavone-treated Atlantic cod (Gadus morhua) liver reveal insights into the cod CYPome. Aquatic Toxicology. 2-10.
- (2012). Conservation and divergence of chemical defense system in the tunicate Oikopleura dioica revealed by genome wide response to two xenobiotics. BMC Genomics. 17 pages.
- (2011). Integrative Environmental Genomics of Cod (Gadus morhua): The Proteomics Approach. Journal of Toxicology and Environmental Health, Part A. 494-507.
- (2010). Identification of a bacterial di-haem cytochrome c peroxidase from Methylomicrobium album BG8. Microbiology (Reading). 2682-2690.
- (2009). Human Naa50p (Nat5/San) Displays Both Protein N-alpha- and N-epsilon-Acetyltransferase Activity. Journal of Biological Chemistry. 31122-31129.
- (2008). The presence of multiple c-type cytochromes at the surface of the methanotrophic bacterium Methylococcus capsulatus (Bath) is regulated by copper. Molecular Microbiology. 15-26.
- (2008). An oxidized tryptophan facilitates copper binding in Methylococcus capsulatus-secreted protein MopE. Journal of Biological Chemistry. 13897-13904.
- (2006). Analysing the outer membrane subproteome of Methylococcus capsulatus (Bath) using proteomics and novel biocomputing tools. Archives of Microbiology. 362-377.
- (2005). Identification of a copper-repressible cytochrome c peroxidase of Methylococcus capsulatus (Bath); a member of a novel group of the bacterial di-heme cytochrome c peroxidase family of proteins. The FEBS Journal. 6324-6335.
- (2005). Characterisation of a prokaryotic hemerythrin from the methanotrophic bacterium Methylococcus capsulatus (Bath). The FEBS Journal. 2428-2440.
- (2004). The core 2 ß-1,6-N-acetylglucosaminyltransferase-M encoded by bovine herpesvirus 4 is not essential for virus replication despite contributing to post-translational modifications of structural proteins. Journal of General Virology. 355-367.
- (2003). The surface-associated and secreted MopE protein of Methylococcus capsulatus (Bath) responds to changes in the concentration of copper in the growth medium. Applied and Environmental Microbiology. 2386-2388.
- (2003). Multiple polypeptide forms observed in two-dimensional gels of Methylococcus capsulatus (Bath) polypeptides are generated during the separation procedure. Electrophoresis. 757-761.
- (2021). PW-Exposed Final Report: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species (OC2021 A-107). .
- (2022). Complex mixture and omics responses in Atlantic cod: a time- and dose-response study.
- (2019). Chemical warfare in the marine environment.
- (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
- (2021). Genomic responses to pollutants in Arctic fish and copepod species.
- (2020). Polar cod and Goliat: How an oil spill may affect polar cod reproduction.
- (2020). Adapting a liver slice culture method for ex vivo toxicological studies in arctic and sub-arctic fish species during sampling cruises.
- (2020). ANTIESTROGENIC EFFECTS OF BENZO[a]PYRENE REVEALED BY TRANSCRIPTOME ANALYSIS IN POLAR COD LIVER SLICE CULTURE.
- (2020). A multi-omics approach to study Ppar-mediated regulation of lipid metabolism in Atlantic cod (Gadus morhua).
- (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
- (2019). Toxicogenomic responses in Atlantic cod (Gadus morhua) after treatment with selected environmental contaminants in vivo and ex vivo.
- (2019). The chemical defensome of Atlantic cod (Gadus morhua).
- (2019). In vitro assessment of estrogenic and androgenic effects of bisphenols on Atlantic cod (Gadus morhua).
- (2019). Effects of agricultural pesticides in aquafeeds on wild fish feeding on leftover pellets near fish farms. Conference talk.
- (2019). EFFECTS OF SELECTED ENVIRONMENTAL ESTROGENS ON EXPRESSION OF FIBROBLAST GROWTH FACTOR SIGNALING PATHWAY GENES IN THE LIVER OF ATLANTIC COD (GADUS MORHUA) IN VIVO AND EX VIVO.
- (2019). Contaminant accumulation and biological responses in Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
- (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons and perfluoroalkyl substances.
- (2019). Assessment of endocrine disrupting effects of bisphenols in Atlantic cod (Gadus morhua) using luciferase reporter assays and precision-cut liver slices.
- (2019). Agricultural pesticides in aquafeeds might harm wild fish feeding on leftover pellets near fish farms.
- (2018). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA).
- (2018). The nuclear receptor complement of Atlantic cod (Gadus morhua) as potential targets for endocrine disrupting compounds.
- (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
- (2018). RNA-seq analysis of transcriptome responses in Atlantic cod (Gadus morhua) precision cut liver slices exposed to benzo[a]pyrene and 17α-ethynylestradiol.
- (2018). Modelling the chemical defensome networks --- a dynamic visualisation of the involved genes and interactions in two fish species and human.
- (2018). Modelling the chemical defensome network - a dynamic visualisation of the involved genes and pathways in two fish species and humans .
- (2018). Modelling The Chemical Defensome Networks - A Comparative Dynamic Visualisation Of The Involved Genes And Interactions In Two Fish Species And Humans.
- (2018). Establishing a cellfree method for xenobiotic detection using ligand activated receptors from the Atlantic cod, Gadus morhua.
- (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
- (2018). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
- (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
- (2018). Characterization of the aryl hydrocarbon receptors Ahr1a and Ahr2a in Atlantic cod (Gadus morhua).
- (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
- (2018). Characterization of the Atlantic cod (Gadus morhua) Aryl hydrocarbon receptors Ahr1a and Ahr2a.
- (2018). Agonistic and antagonistic effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
- (2017). PRECISION-CUT LIVER SLICES (PCLS) FOR TOXICOGENOMIC STUDIES IN ATLANTIC COD (Gadus morhua): THE dCOD 1.0 PROJECT.
- (2017). Integrative transcriptome and proteome analysis reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with PCB 153.
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) after caging at a capped waste disposal site in Kollevåg, Western Norway .
- (2017). CHARACTERIZATION OF THE ARYL HYDROCARBON RECEPTORS AHR1B AND AHR2 IN ATLANTIC COD (GADUS MORHUA).
- (2016). Toxicogenomics as a tool for understanding responses to pollutants in organisms: Using Atlantic cod (Gadus morhua) and a systems biology approach to environmental toxicology.
- (2016). Integrative -omics analyses reveal perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) exposed to the persistent organic pollutant PCB 153.
- (2016). Chemical warfare in the marine environment: genomic survey of the Atlantic cod (Gadus morhua) defensome reveals the absence of an important xenosensor.
- (2014). ALTERATIONS IN THE HEPATIC PROTEOME OF POLAR COD (BOREOGADUS SAIDA) AFTER DIETARY EXPOSURE TO BENZO[A]PYRENE.
- (2011). Genome-wide gene expression and proteome analysis of cod (Gadus morhua) liver after treatment with methylmecury and PCB153.
- (2003). The expression of the surface associated MopE protein of Methylococcus capsulatus (Bath) is regulated by the concentration of copper in the growth medium.
- (2003). Proteome studies on the methanotrophic bacterium Methylococcus capsulatus (Bath).
- (2003). Multiple polypeptide forms observed in twodimensional gels of Methylococcus capsulatus (Bath)polypeptides are generated during the separation procedure.
- (2002). Initial proteome studies of Methylococcus capsulatus (Bath).
- (2005). A study of McHr – a novel prokaryotic hemerythrin from Methylococcus capsulatus (Bath).
- (2004). Studies of Methylococcus capsulatus (Bath): The surface associated protein SapE.
- (2001). The proteome of Methylococcus capsulatus; An initial study by two-domentional gel electrophoresis.
- (2018). Torsken manglar eit viktig gen i forsvaret mot miljøgifter. Forskning.no.
- (2019). Molecular characterization of key components of the adaptive immune system in ballan wrasse (Labrus bergylta).
- (2005). Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath).
- (2012). Integrative environmental genomics of cod (Gadus morhua) reveal the mechanisms underlying MeHg- and PCB153 induced toxicity. Comparative Biochemistry and Physiology A. S49-S49.
- (2010). iCod: Integrative environmental genomics of cod (Gadus morhua); the proteomics approach. Comparative Biochemistry and Physiology A. S44-S44.
- (2010). The chaperone-like protein HYPK acts together with NatA in cotranslational N-terminal acetylation and prevention of Huntingtin aggregation. The FEBS Journal. 185-185.
- (2010). Human Naa50p (Nat5/San) displays both protein N-alpha- and N-epsilon-Acetyltransferase activity. The FEBS Journal. 182-182.
- (2022). Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene.
- (2022). Reproductive development in polar cod (Boreogadus saida) exposed to crude oil and food variability.
- (2021). Development of a battery of Atlantic cod receptor-based reporter bioassays for assessing environmental toxicity of sediments and chemicals.
- (2019). dCOD 1.0: DECODING THE SYSTEMS TOXICOLOGY OF ATLANTIC COD (GADUS MORHUA) – HIGHLIGHTS SO FAR.
- (2019). THE CHEMICAL DEFENSOME OF ATLANTIC COD (GADUS MORHUA): HOW DOES IT DIFFER FROM DEFENSOME NETWORKS IN OTHER TELEOST SPECIES?
- (2019). Polycyclic aromatic hydrocarbons potentiate vitamin D receptor (Vdr) activation by calcitriol in Atlantic cod (Gadus morhua).
- (2019). In vitro assessment of estrogenic effects of bisphenols on Atlantic cod (Gadus morhua).
- (2019). Evaluation of estrogenic effects of bisphenols using luciferase reporter assay and Atlantic cod (Gadus morhua) liver slice culture.
- (2019). Chemical warfare in the aquatic environment - The chemical defensome networks of model fish species.
- (2019). Biological responses of Atlantic cod (Gadus morhua) exposed to polycyclic aromatic hydrocarbons (PAHs) and perfluoroalkyl substances (PFASs) .
- (2019). Assessment of produced water toxicity using in vitro tools developed from Atlantic cod (Gadus morhua).
- (2018). PW-Exposed: Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species.
- (2018). MODELLING THE CHEMICAL DEFENSOME NETWORKS - a comparative visualisation of the defense genes and interactions in two fish species and human.
- (2018). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
- (2018). Effects of perfluorinated compounds on Atlantic cod (Gadus morhua) PPARαa and PPARαb nuclear receptors.
- (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua).
- (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
- (2017). dCod 1.0: decoding the systems toxicology of Atlantic cod (Gadus morhua) - WP8: biomarkers and xenosensors.
- (2017). dCod 1.0 decoding the systems toxicology of Atlantic cod.
- (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2017). Using precision-cut liver slices (PCLS) and luciferase reporter gene assays to characterise the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2017). Using precision cut liver slices (PCLS) for studying effects of environmental contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
- (2017). Studying estrogenic effects of environmental pollutants by using the Atlantic cod (Gadus morhua) estrogen receptor α and a reporter gene assay.
- (2017). Peroxisome proliferator-activated receptors (PPARs) as tools for studying effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
- (2017). Establishing a cell-free method for xenobiotic detection using ligand activated receptors from the Atlantic cod (Gadus morhua).
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
- (2017). Ecotoxicological responses in Atlantic cod (Gadus morhua) following caging near a previously capped waste disposal site in Kollevågen, Askøy, Norway .
- (2016). Using precision-cut liver slices (PCLS) and luciferase reporter gene assay to characterize the aryl hydrocarbon receptors (Ahr) in Atlantic cod (Gadus morhua).
- (2016). Systems Toxicology Studies to Investigate Mechanisms of Toxicity of Environmental Chemicals Using Atlantic cod (Gadus morhua) as a Model Organism.
- (2016). Peroxisome proliferator-activated receptors (PPARs) as tools to study effects of contaminants on the Atlantic cod (Gadus morhua) lipid metabolism.
- (2016). Integrated analysis of transcriptome and proteome reveals perturbation of lipid metabolic pathways in the liver of Atlantic cod (Gadus morhua) treated with the persistent organic pollutant PCB 153 .
- (2016). Effektar på lipidmetabolismen til atlanterhavstorsk (Gadus morhua) etter eksponering mot enkeltsambindingar og blandingar av miljøgiftar.
- (2014). Alterations in the hepatic proteome of polar cod (Boreogadus saida) after dietary exposure to benzo(a)pyrene .
- (2012). Integrative environmental genomics of Atlantic cod (Gadus morhua): exposure of cod liver slices to environmental contaminants.
- (2010). Human Naa50p (Nat5/San) Displays Both Protein Na-and Ne-Acetyltransferase activity.
- (2004). Surface proteins of M. capsulatus (Bath) possibly involved in copper uptake.
- (2004). Copper-regulation of some surface-exposed and secreted proteins of the methane-oxidizing bacterium Methylococcus capsulatus (Bath).
- (2004). Copper homeostasis in Methylococcus capsulatus.
- (2004). An introduction to copper homeostasis in Methylococcus capsulatus.
- (2003). Identification of the ORF upstream of MopE in Methylococcus capsulatus.
- (2003). Differential expression in sMMO and pMMO producing cells of Methylococcus capsulatus (Bath).
- (2002). Initial proteome studies on Methylococcus capsulatus (Bath).
- (2002). Characterization of copper-repressible extracellular protein of Methylococcus capsulatus (Bath).
- (2011). The copper responding surfaceome of Methylococccus capsulatus Bath. FEMS Microbiology Letters. 97-104.
- (2011). Methylococcus capsulatus (Bath): From Genome to Protein Function, and Vice Versa. Methods in Enzymology. 63-79.
- (2011). METHANOTROPH OUTER MEMBRANE PREPARATION. Methods in Enzymology. 167-176.
More information in national current research information system (CRIStin)
2023-2027; Whales and polar bear in a petri dish: decoding marine mammal toxicology through in vitro and in silico approaches – Marma-detox (RCN), WP-leader
2023-2027; Reproductive toxicity and generational effects of a contaminant mixture in fish (ToxiGen)(RCN), Partner
2021-2025; Effects of antifouling copper coating in aquaculture – implications for fish health, performance and sustainability of production (CAPS)(RCN 325849), WP-leader
2020-2024; Distribution, fate and effects of microplastics in the appendicularian zooplankton Oikopleura dioica (UiB), PI
2021; dCod Pollution Sensing Kit (RCN 323092), Partner
2020-2023; Joint evaluation and mitigation of emerging contaminant risks (INTPART)(RCN (309476), WP-leader
2020-2022; Cellular responses to contaminant exposure in marine mammals from the Arctic (The FRAM-centre), Partner
2020; 8th Norwegian Environmental Toxicology Symposium (NETS) – Ocean Health in the Anthropocene (RCN 311098), PI
2018-2021; Produced water fractionation and advanced chemical and toxicological characterization using sensitive life stages of marine fish species (PW-EXPOSED)(RCN 280511), WP-leader
2016-2021; dCod 1.0 – decoding the systems toxicology of Atlantic cod (Gadus morhua)(RCN(248840), WP-leader
2015-2019; iCod 2.0 - integrative environmental genomics of Atlantic cod (Gadus morhua)(RCN 244564), PI
2015-2019; Network for improving research based higher education in basic and applied microbiology( EURASIA, PEA-LT-2016/10095), Partner
2015-2016; In vitro fish: New 3D models for nutritional and toxicological research RCN (244507), Partner
2009-2013; iCod – integrative envionmental genomics of cod (Gadus morhua)(RCN (92441) , PI
2005; Philosophiae Doctor (PhD) in molecular biology. Title of thesis: ”Molecular analyses of copper responding proteins in Methylococcus capsulatus (Bath)”. Department of Molecular Biology, University of Bergen, Norway
2001; Candidatus scientiarum in molecular biology. Title of thesis: ”The proteome of Methylococcus capsulatus (Bath); An initial study by two-dimensional gel electrophoresis”. Department of Molecular Biology, University of Bergen, Norway
1998; 35 ECTS from the Bachelor´s degree programme in Biotechnology. Hedmark University College, Hamar, Norway
Yadetie F, Brun NR, Giebichenstein J, Dmoch K, Hylland K, Borgå K, Karlsen OA, Goksøyr A. Transcriptome responses in copepods Calanus finmarchicus, Calanus glacialis and Calanus hyperboreus exposed to phenanthrene and benzo[a]pyrene. Mar Genomics. 2022 Aug 12;65:100981. doi: 10.1016/j.margen.2022.100981.
Søderstrøm S, Lille-Langøy R, Yadetie F, Rauch M, Milinski A, Dejaegere A, Stote RH, Goksøyr A, Karlsen OA*. Agonistic and potentiating effects of perfluoroalkyl substances (PFAS) on the Atlantic cod (Gadus morhua) peroxisome proliferator-activated receptors (Ppars). Environ Int. 2022 May;163:107203. doi: 10.1016/j.envint.2022.107203.
Strobel A, Lille-Langøy R, Segner H, Burkhardt-Holm P, Goksøyr A, Karlsen OA. Xenobiotic metabolism and its physiological consequences in high-Antarctic Notothenioid fishes. Polar Biol. 2022;45(2):345-358. doi: 10.1007/s00300-021-02992-4.
Dale K, Yadetie F, Horvli T, Zhang X, Frøysa HG, Karlsen OA, Goksøyr A. Single PFAS and PFAS mixtures affect nuclear receptor- and oxidative stress-related pathways in precision-cut liver slices of Atlantic cod (Gadus morhua). Sci Total Environ. 2022 Mar 25;814:152732. doi: 10.1016/j.scitotenv.2021.152732.
Lille-Langøy R, Jørgensen KB, Goksøyr A, Pampanin DM, Sydnes MO, Karlsen OA*. Substituted Two- to Five-Ring Polycyclic Aromatic Compounds Are Potent Agonists of Atlantic Cod (Gadus morhua) Aryl Hydrocarbon Receptors Ahr1a and Ahr2a. Environ Sci Technol. 2021 Nov 16;55(22):15123-15135. doi: 10.1021/acs.est.1c02946.
Aranguren-Abadía L, Yadetie F, Donald CE, Sørhus E, Myklatun LE, Zhang X, Lie KK, Perrichon P, Nakken CL, Durif C, Shema S, Browman HI, Skiftesvik AB, Goksøyr A, Meier S, Karlsen OA*. Photo-enhanced toxicity of crude oil on early developmental stages of Atlantic cod (Gadus morhua). Sci Total Environ. 2022 Feb 10;807(Pt 1):150697. doi: 10.1016/j.scitotenv.2021.150697.
Goksøyr SØ, Goldstone J, Lille-Langøy R, Lock EJ, Olsvik PA, Goksøyr A, Karlsen OA*. Polycyclic aromatic hydrocarbons modulate the activity of Atlantic cod (Gadus morhua) vitamin D receptor paralogs in vitro. Aquat Toxicol. 2021 Jul 16;238:105914. doi: 10.1016/j.aquatox.2021.105914.
Goksøyr SØ, Sørensen H, Grøsvik BE, Pampanin DM, Goksøyr A, Karlsen OA*. Toxicity assessment of urban marine sediments from Western Norway using a battery of stress-activated receptors and cell-based bioassays from fish. Environ Toxicol Pharmacol. 2021 Oct;87:103704. doi: 10.1016/j.etap.2021.103704.
Yadetie F, Brun NR, Vieweg I, Nahrgang J, Karlsen OA, Goksøyr A. Transcriptome responses in polar cod (Boreogadus saida) liver slice culture exposed to benzo[a]pyrene and ethynylestradiol: insights into anti-estrogenic effects. Toxicol In Vitro. 2021 Sep;75:105193. doi: 10.1016/j.tiv.2021.105193.
Eide M, Zhang X, Karlsen OA, Goldstone JV, Stegeman J, Jonassen I, Goksøyr A. The chemical defensome of five model teleost fish. Sci Rep. 2021 May 18;11(1):10546. doi: 10.1038/s41598-021-89948-0.