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Ola Myklebost's picture

Ola Myklebost

Professor, molecular oncology
Department of Clinical Science
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  • E-mailOla.Myklebost@uib.no
  • Phone+47 55 97 45 73+47 900 87 139
  • Visitor Address
    Haukeland universitetssykehus, Laboratoriebygget
    5009 Bergen
  • Postal Address
    Postboks 7804
    5020 Bergen

Recently started in Bergen, associated to the Research Group for Precision Oncology, but still supervise projects in my old group at the Norwegian Radium Hospital in Oslo. There we focus on sarcomas, tumours of connective tissues. From Bergen I am leading the two national projects, Norwegian Cancer Genomics Consortium (NCGC) and Norwegian Sarcoma Consortium (NoSarC). My new web page at UiB is at myklebost.uib.no.

Academic article
  • Show author(s) (2022). miR-486-5p expression is regulated by DNA methylation in osteosarcoma. BMC Genomics.
  • Show author(s) (2022). Clonal evolution in primary breast cancers under sequential epirubicin and docetaxel monotherapy. Genome Medicine. 1-18.
  • Show author(s) (2022). Clonal evolution after treatment pressure in multiple myeloma: heterogenous genomic aberrations and transcriptomic convergence. Leukemia. 1887-1897.
  • Show author(s) (2021). The expressed mutational landscape of microsatellite stable colorectal cancers. Genome Medicine.
  • Show author(s) (2021). Multimodal analysis of cell-free DNA whole-genome sequencing for pediatric cancers with low mutational burden. Nature Communications. 1-16.
  • Show author(s) (2021). Methylation-dependent SUMOylation of the architectural transcription factor HMGA2. Biochemical and Biophysical Research Communications - BBRC. 91-97.
  • Show author(s) (2021). Discovery of novel candidates for anti-liposarcoma therapies by medium-scale high-throughput drug screening. PLOS ONE. 1-23.
  • Show author(s) (2021). Clinical and molecular implications of NAB2-STAT6 fusion variants in solitary fibrous tumour. Pathology (Sydney). 713-719.
  • Show author(s) (2021). Cancer Predisposition Sequencing Reporter (CPSR): A flexible variant report engine for high-throughput germline screening in cancer. International Journal of Cancer. 1-6.
  • Show author(s) (2020). Sex differences in oncogenic mutational processes. Nature Communications. 1-24.
  • Show author(s) (2020). Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples. Nature Communications. 1-27.
  • Show author(s) (2020). Pan-cancer analysis of whole genomes. Nature. 82-93.
  • Show author(s) (2020). Mutational dynamics and immune evasion in diffuse large B-cell lymphoma explored in a relapse-enriched patient series. Blood Advances. 1859-1866.
  • Show author(s) (2020). Cell Fusion of Mesenchymal Stem/Stromal Cells and Breast Cancer Cells Leads to the Formation of Hybrid Cells Exhibiting Diverse and Individual (Stem Cell) Characteristics. International Journal of Molecular Sciences. 1-16.
  • Show author(s) (2020). Accurate 3-gene-signature for early diagnosis of liposarcoma progression. Clinical Sarcoma Research. 1-11.
  • Show author(s) (2019). Preclinical Evaluation of the Pan-FGFR Inhibitor LY2874455 in FRS2-Amplified Liposarcoma. Cells.
  • Show author(s) (2018). Sample-Index Misassignment Impacts Tumour Exome Sequencing. Scientific Reports. 1-6.
  • Show author(s) (2018). Real-time vital mineralization detection and quantification during in vitro osteoblast differentiation. Biological Procedures Online. 1-5.
  • Show author(s) (2018). Preclinical evaluation of vemurafenib as therapy for BRAFV600E mutated sarcomas. International Journal of Molecular Sciences. 1-15.
  • Show author(s) (2018). Patterns of genomic evolution in advanced melanoma. Nature Communications. 1-12.
  • Show author(s) (2018). Noninvasive Detection of ctDNA Reveals Intratumor Heterogeneity and Is Associated with Tumor Burden in Gastrointestinal Stromal Tumor. Molecular Cancer Therapeutics. 2473-2480.
  • Show author(s) (2018). Multifocal primary prostate cancer exhibits high degree of genomic heterogeneity. European Urology. 1-8.
  • Show author(s) (2018). Evaluation of commercial DNA and RNA extraction methods for high-throughput sequencing of FFPE samples. PLOS ONE. 1-12.
  • Show author(s) (2017). Use of liquid biopsies to monitor disease progression in a sarcoma patient: a case report. BMC Cancer. 1-6.
  • Show author(s) (2017). Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma. Nature Communications. 1-8.
  • Show author(s) (2017). PP2A regulatory subunit b55γ is a gatekeeper of osteoblast maturation and lineage maintenance. Stem Cells and Development. 1375-1383.
  • Show author(s) (2017). Multilevel genomics of colorectal cancers with microsatellite instability – clinical impact of JAK1 mutations and consensus molecular subtype 1. Genome Medicine.
  • Show author(s) (2017). Multi-omics of 34 colorectal cancer cell lines - a resource for biomedical studies. Molecular Cancer. 1-16.
  • Show author(s) (2017). Monitoring multiple myeloma by quantification of recurrent mutations in serum. Haematologica. 1266-1272.
  • Show author(s) (2017). High number of kinome-mutations in non-small cell lung cancer is associated with reduced immune response and poor relapse-free survival. International Journal of Cancer. 184-190.
  • Show author(s) (2017). Analysis of the miR-34 family functions in breast cancer reveals annotation error of miR-34b. Scientific Reports. 1-10.
  • Show author(s) (2016). Unscrambling the genomic chaos of osteosarcoma reveals extensive transcript fusion, recurrent rearrangements and frequent novel TP53 aberrations. OncoTarget. 5273-5288.
  • Show author(s) (2016). The genomic landscape of pancreatic and periampullary adenocarcinoma. Cancer Research. 5092-5102.
  • Show author(s) (2016). TP53 mutation spectrum in smokers and never smoking lung cancer patients. Frontiers in Genetics.
  • Show author(s) (2016). Preclinical evaluation of potential therapeutic targets in dedifferentiated liposarcoma. OncoTarget. 54583-54595.
  • Show author(s) (2016). Monogenic and polygenic determinants of sarcoma risk: an international genetic study. The Lancet Oncology. 1261-1271.
  • Show author(s) (2016). Genome analysis of osteosarcoma progression samples identifies FGFR1 overexpression as a potential treatment target and CHM as a candidate tumor suppressor gene. PLOS ONE.
  • Show author(s) (2015). Metabolic reprogramming of metastatic breast cancer and melanoma by Let-7a microRNA. OncoTarget. 2451-2465.
  • Show author(s) (2015). Genomic landscape of liposarcoma. OncoTarget. 42429-42444.
  • Show author(s) (2015). Frequent somatic transfer of mitochondrial DNA into the nuclear genome of human cancer cells. Genome Research.
  • Show author(s) (2015). Bone marrow stroma-derived PGE<sub>2</sub> protects BCP-ALL cells from DNA damage-induced p53 accumulation and cell death. Molecular Cancer.
  • Show author(s) (2015). BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis. Blood Cancer Journal. 1-7.
  • Show author(s) (2014). Workshop Report on the 2nd Joint ENCCA/EuroSARC European Bone Sarcoma Network Meeting: Integration of Clinical Trials with Tumour Biology. Clinical Sarcoma Research.
  • Show author(s) (2014). The tankyrase-specific inhibitor JW74 affects cell cycle progression and induces apoptosis and differentiation in osteosarcoma cell lines. Cancer Medicine. 36-46.
  • Show author(s) (2014). The regulatory landscape of osteogenic differentiation. Stem Cells. 2780-2793.
  • Show author(s) (2014). The Architecture and Evolution of Cancer Neochromosomes. Cancer Cell. 653-667.
  • Show author(s) (2014). TRAP1 is a novel interaction partner of PML, localised with PML in nuclear bodies and relocating with PML to the cytoplasm following stress. Annual Research & Review in Biology. 3026-3036.
  • Show author(s) (2014). Reexpression of LSAMP inhibits tumor growth in a preclinical osteosarcoma model. Molecular Cancer.
  • Show author(s) (2014). Performance comparison of four exome capture systems for deep sequencing. BMC Genomics.
  • Show author(s) (2014). Generation and characterization of an immortalized human mesenchymal stromal cell line. Stem Cells and Development. 2377-2389.
  • Show author(s) (2014). Generation and Characterisation of Novel Pancreatic Adenocarcinoma Xenograft Models and Corresponding Primary Cell Lines. PLOS ONE. 12 pages.
  • Show author(s) (2014). Extensive transduction of non-reptitive DNA mediated by L1 retrotransposition in cancer genomes. Science. 1251343-1251343.
  • Show author(s) (2013). Photochemical internalization of CD133-targeting immunotoxins efficiently depletes sarcoma cells with stem-like properties and reduces tumorigenicity. Biochimica et Biophysica Acta - General Subjects. 4235-4243.
  • Show author(s) (2013). Identification of PPAP2B as a novel recurrent translocation partner gene of HMGA2 in lipomas. Genes, Chromosomes and Cancer. 580-590.
  • Show author(s) (2013). IR/IGF1R signaling as potential target for treatment of high-grade osteosarcoma. BMC Cancer. 9 pages.
  • Show author(s) (2013). Functional characterization of osteosarcoma cell lines and identification of mRNAs and miRNAs associated with aggressive cancer phenotypes. British Journal of Cancer. 2228-2236.
  • Show author(s) (2013). Epigenetic Regulation and Functional Characterization of MicroRNA-142 in Mesenchymal Cells. PLOS ONE.
  • Show author(s) (2013). Distinct H3F3A and H3F3B driver mutations define chondroblastoma and giant cell tumor of bone. Nature Genetics. 1479-U105.
  • Show author(s) (2013). Correlation of TP53 and MDM2 genotypes with response to therapy in sarcoma. Cancer. 1013-1022.
  • Show author(s) (2013). Comparison of glioma stem cells to neural stem cells from the adult human brain identifies dysregulated Wnt- signaling and a fingerprint associated with clinical outcome. Experimental Cell Research. 2230-2243.
  • Show author(s) (2013). Common fusion transcripts identified in colorectal cancer cell lines by high throughput RNA sequencing. Translational Oncology. 546-553.
  • Show author(s) (2013). A small molecule approach to engineering vascularized tissue. Biomaterials. 3053-3063.
  • Show author(s) (2012). Preclinical xenograft models of human sarcoma show nonrandom loss of aberrations. Cancer. 558-570.
  • Show author(s) (2012). Modulation of the Osteosarcoma Expression Phenotype by MicroRNAs. PLOS ONE. 12 pages.
  • Show author(s) (2012). Integrative Analysis Reveals Relationships of Genetic and Epigenetic Alterations in Osteosarcoma. PLOS ONE. 20 pages.
  • Show author(s) (2012). Identification of osteosarcoma driver genes by integrative analysis of copy number and gene expression data. Genes, Chromosomes and Cancer. 696-706.
  • Show author(s) (2012). Global gene expression profiling of human osteosarcomas reveals metastasis-associated chemokine pattern. Sarcoma. 12 pages.
  • Show author(s) (2012). Characterization of liposarcoma cell lines for preclinical and biological studies. Sarcoma.
  • Show author(s) (2012). Adipocyte Differentiation of Human Bone Marrow-Derived Stromal Cells Is Modulated by MicroRNA-155, MicroRNA-221, and MicroRNA-222. Stem Cells and Development. 873-883.
  • Show author(s) (2011). mRNA expression profiles of primary high-grade central osteosarcoma are preserved in cell lines and xenografts. BMC Medical Genomics. 11 pages.
  • Show author(s) (2011). Tumor-Infiltrating Macrophages Are Associated with Metastasis Suppression in High-Grade Osteosarcoma: A Rationale for Treatment with Macrophage Activating Agents. Clinical Cancer Research. 2110-2119.
  • Show author(s) (2011). Metastasis suppression by tumor-infiltrating macrophages in high-grade osteosarcoma. Clinical Cancer Research. 2110-2119.
  • Show author(s) (2011). MDM2 antagonist Nutlin-3a potentiates antitumour activity of cytotoxic drugs in sarcoma cell lines. BMC Cancer. 11 pages.
  • Show author(s) (2011). Genomic validation of preclinical xenograft models of human sarcoma reveals recurrent loss of aberrations. Cancer. 558-570.
  • Show author(s) (2011). Genome wide single cell analysis of chemotherapy resistant metastatic cells in a case of gastroesophageal adenocarcinoma. BMC Cancer. 8 pages.
  • Show author(s) (2011). Combined ALDH and CD133 expression defines a stem-like cancer cell population in liposarcoma xenograft. Clinical Sarcoma Research. 8.
  • Show author(s) (2011). Adipocyte Differentiation of Immortalized Human Bone Marrow-Derived Stromal Cells is Modulated by microRNA-155, microRNA-221 and microRNA-222. Stem Cells and Development.
  • Show author(s) (2010). Molecular Characterization of Commonly Used Cell Lines for Bone Tumor Research: A Trans-European EuroBoNet Effort. Genes, Chromosomes and Cancer. 40-51.
  • Show author(s) (2010). Identification of target genes for wild type and truncated HMGA2 in mesenchymal stem-like cells. BMC Cancer. 14 pages.
  • Show author(s) (2010). Genomic alterations reveal potential for higher grade transformation in follicular lymphoma and confirm parallel evolution of tumor cell clones. Blood. 1489-1497.
  • Show author(s) (2010). Extensive adipogenic and osteogenic differentiation of patterned human mesenchymal stem cells in a microfluidic device. Lab on a Chip. 1401-1409.
  • Show author(s) (2010). Evaluation of high-resolution microarray platforms for genomic profiling of bone tumours. BMC Research Notes. 223.
  • Show author(s) (2010). DNA Copy Number Changes in Human Malignant Fibrous Histiocytomas by Array Comparative Genomic Hybridisation. PLOS ONE. 10 pages.
  • Show author(s) (2010). Characterization of Treatment Response to Recombinant Interferon-α2b in Osteosarcoma Xenografts. Journal of Cancer Science & Therapy. 16-25.
  • Show author(s) (2010). A Tissue Microarray Study of Osteosarcoma: Histopathologic and Immunohistochemical Validation of Xenotransplanted Tumors as Preclinical Models. Applied immunohistochemistry & molecular morphology (Print). 453-461.
  • Show author(s) (2009). Upregulation of stem cell genes in multidrug resistant K562 leukemia cells. Leukemia Research. 1379-1385.
  • Show author(s) (2009). Molecular characterization of commonly used cell lines for bone tumor research. A trans-European EuroBoNet effort. Genes, Chromosomes and Cancer. 40-51.
  • Show author(s) (2009). LSAMP, a Novel Candidate Tumor Suppressor Gene in Human Osteosarcomas, Identified by Array Comparative Genomic Hybridization. Genes, Chromosomes and Cancer. 679-693.
  • Show author(s) (2008). High-resolution analysis of genetic stability of human adipose tissue stem cells cultured to senescence. Journal of Cellular and Molecular Medicine. 553-563.
  • Show author(s) (2008). GeneCount: genome-wide calculation of absolute tumor DNA copy numbers from array comparative genomic hybridization data. Genome Biology. R86.
  • Show author(s) (2008). DNA copy number changes in high-grade malignant peripheral nerve sheath tumors by array CGH. Molecular Cancer. 11 pages.
  • Show author(s) (2008). Chromosomal aberrations in head and neck squamous cell carcinomas in Norwegian and Sudanese populations by array comparative genomic hybridization. Oncology Reports. 825-843.
  • Show author(s) (2008). Chromosomal aberrations in head and neck squamous cell carcinomas in Norwegian and Sudanese populations by array comparative genomic hybridization. Oncology Reports. 825-843.
  • Show author(s) (2007). Potential for treatment of liposarcomas with the MDM2 antagonist Nutlin-3A. International Journal of Cancer.
  • Show author(s) (2007). Gene expression profiles of primary colorectal carcinomas, liver metastases, and carcinomatoses. Molecular Cancer. 16 pages.
  • Show author(s) (2007). Diagnostic and prognostic gene expression signatures in 177 soft tissue sarcomas: hypoxia-induced transcription profile signifies metastatic potential. BMC Genomics.
  • Show author(s) (2006). Sampling effects on gene expression data from a human tumour xenograft. Scandinavian Journal of Laboratory Animal Science. 17-34.
  • Show author(s) (2006). Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas. Cancer Research.
  • Show author(s) (2006). Array comparative genomic hybridization reveals distinct DNA copy number differences between gastrointestinal stromal tumors and leiomyosarcomas. Cancer Research. 8984-8993.
  • Show author(s) (2005). Translocation t(14;18)and gain of chromosome 18/BCL2: effects on BCL2 exression and apoptosis in B-cell non-Hodgkin's lymphomas. Leukemia. 2313-2323.
  • Show author(s) (2005). Molekylærbiologisk diagnostikk ved bein- og bløtvevssvulster. Tidsskrift for Den norske legeforening. 3286-3289.
  • Show author(s) (2005). Mapping and characterizatin of the amplicon near APOA2 in Iq23 in human sarcomas by FISH and array CGH. Molecular Cancer. 39-50.
  • Show author(s) (2005). Limitations of mRNA amplification from small-size cell samples. BMC Genomics. 147.
  • Show author(s) (2005). Expression patterns of cell cycle components in sporadic and neurofibromatosis type 1 related malignant peripheral nerve sheath tumors. Journal of Neuropathology and Experimental Neurology. 74-81.
  • Show author(s) (2004). Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data. BMC Bioinformatics. art. no.-60.
  • Show author(s) (2004). The response of malignant B lymphocytes to ionizing radiation: Geneexpression and genotype. International Journal of Cancer. 935-942.
  • Show author(s) (2004). Profound influence of microarray scanner characteristics on gene expression ratios: analysis and procedure for correction. BMC Genomics. 10.
  • Show author(s) (2004). M-CGH: analysing microarray-based CGH experiments. BMC Bioinformatics.
  • Show author(s) (2004). M-CGH: Analysing microarray-based CGH experiments. BMC Bioinformatics. art. no.-74.
  • Show author(s) (2004). Constitutive expression of the AP-1 transcription factors c-jun, junD, junB and c-fos and the marginal zone B-cell transcription factor Notch2 in splenic marginal zone lymphoma. Journal of Molecular Diagnostics. 297-307.
  • Show author(s) (2004). Analysis of the humoral immune response to immunoselected phage-displayed peptides by a microarray-based method. Proteomics. 2572-2582.
  • Show author(s) (2003). Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data. BMC Bioinformatics. 60.
  • Show author(s) (2003). Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data. BMC Bioinformatics. 60.
  • Show author(s) (2003). Tumor classification and marker gene prediction by feature selection and fuzzy c-means clustering using microarray data. BMC Bioinformatics. 60.
  • Show author(s) (2003). MGraph: graphical models for microarray data analysis. Bioinformatics. 2210-2211.
  • Show author(s) (2003). Interferon-gamma suppresses S100A4 transciption independently of apoptosis or cell cycle arrest. British Journal of Cancer. 1995-2001.
  • Show author(s) (2003). Effects of mRNA amplification on gene expression ratios in cDNA experiments estimated by analysis of variance. BMC Genomics.
  • Show author(s) (2003). Amplification and overexpression of COPS3 in osteosarcomas potentially target TP53 for proteasome-mediated degradation. Oncogene. 5358-5361.
  • Show author(s) (2003). 11q13 alterations in two cases of hibernoma: large heterozygous deletions and rearrangement breakpoints near GARP in 11q13.5. Genes, Chromosomes and Cancer. 389-395.
  • Show author(s) (2002). The SYT-SSX1 fusion type of synovial sarcoma is associated with increased expression of cyclin A and D1. A link between t(X;18)(p11;2;q11.2) and the cell cycle machinery. Oncogene. 5791-5796.
  • Show author(s) (2002). Positional cloning identifies a novel cyclophilin as a candidate amplified oncogene in 1q21. Oncogene. 2261-2269.
  • Show author(s) (2002). Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study. BMC Bioinformatics.
  • Show author(s) (2002). Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study. Bioinformatics. 36.
  • Show author(s) (2002). Clustering of the SOM easily reveals distinct gene expression patterns: results of a reanalysis of lymphoma study. BMC Bioinformatics.
  • Show author(s) (2002). Analysis of repeatability in spotted cDNA microarrays. Nucleic Acids Research (NAR). 3235-3244.
  • Show author(s) (2001). Måling av genaktivitet med DNA mikromatriser (mikroarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. 1225-1228.
  • Show author(s) (2001). Måling av genaktivitet med DNA mikromatriser (mikroarray). Molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening. 1225-1228.
  • Show author(s) (2001). Mikromatriser i kreftforskning: Nå trenger vi ikke å bare lete under gatelyktene! Tidsskrift for Den norske legeforening. 2498-2503.
  • Show author(s) (2001). Genterapi ved kreft. Tidsskrift for Den norske legeforening. 482-488.
  • Show author(s) (2001). Dedifferentiation of a well-differentiated liposarcoma to a highly malignant osteosarcoma:amplification of 12q14 at all stages and gain of 1q22-q24 associated with metastases. Cancer Genetics and Cytogenetics. 100-111.
  • Show author(s) (2001). Dedifferentiation of a well-differentiated liposarcoma to a highly malignant metastatic osteosarcoma: amplification of 12q14 at all stages and gain of 1q22-q24 associated with metastases. Cancer Genetics and Cytogenetics. 100-111.
  • Show author(s) (2001). Dedifferentiation of a WDLPS to a highly malignant osteogenic tumor is associated with high-level amplification og 12q14-q22 and gain of 1q22. Cancer Genetics and Cytogenetics. 100-111.
  • Show author(s) (2001). DNA mikroarray- vindu mot tusentals gen. NBS-nytt. 482-488.
  • Show author(s) (2001). A well-differentiated liposarcoma with a new type of chromosome 12-derived markers. Cancer Genetics and Cytogenetics. 13-18.
  • Show author(s) (2000). Frequent allelic loss of 9p21 (p16INK4A) and other genomic imbalances in human malignant fibruos histiocytoma. Cancer Genetics and Cytogenetics. 89-98.
  • Show author(s) (2000). Frequent allelic loss of 9p21 (p16INK4A) and other genomic imbalances in human malignant fibruos histiocytoma. Cancer Genetics and Cytogenetics.
  • Show author(s) (2000). Dedifferentiation of a WDLPS to a highly malignant osteogenic tumor is associated with high-level amplification of 12q14-q22 and gain of 1q22. Cancer Genetics and Cytogenetics.
  • Show author(s) (2000). DNA Mikroarray- molekylære og teknologiske prinsipper. Tidsskrift for Den norske legeforening.
  • Show author(s) (2000). Characterization of centromere alterations in liposarcomas. Genes, Chromosomes and Cancer. 117-129.
  • Show author(s) (2000). Characterization of centromere alterations in liposarcomas. Genes, Chromosomes and Cancer. 117-129.
  • Show author(s) (2000). Characterisation of etopic sequences from tumor-associated, truncated HMGIC genes shows recurrent involvement of spesific chromosomal regions. Genes, Chromosomes and Cancer.
  • Show author(s) (1999). Structure of ring and giant rod marker chromosomes in adipose tissue tumors: A study combining fluorescent in situ hybridization, comparative genomic hybridization, molecular analyses and immunohistochemistry. Genes, Chromosomes and Cancer. 30-41.
  • Show author(s) (1999). Sensitive method for FISH chracterisation of breast cancer cells in bone marrow aspirates. Molecular Pathology. 68-74.
  • Show author(s) (1999). Chromosome band 9p21 is frequently altered in malignant peripheral nerve sheath tumors from patients with neurofibromatosis type 1. Studies of CDKN2A and other genes og the pRB pathway. Genes, Chromosomes and Cancer. 151-160.
  • Show author(s) (1999). Characterization of the 17p amplicon inhuman sarcomas - microsatellite marker analysis. International Journal of Cancer. 329-333.
  • Show author(s) (1999). A novel chromosomal region of allelic loss, 4q32-q34, in human osteosarcomas revealed by representational difference analysis. Genes, Chromosomes and Cancer. 115-120.
  • Show author(s) (1998). Molecular characterisation of a novel amplicon at 1q21-q22 in human sarcomas. British Journal of Cancer. 495-503.
  • Show author(s) (1997). Recurrent gains of 1q, 8 and 12 in the Ewing family of tumors by cemparative genomic hybridisation. British Journal of Cancer. 1403-1409.
  • Show author(s) (1997). HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas. Oncogene. 2935-2941.
  • Show author(s) (1997). Cytogenetics and molecular genetics of bone and soft tissue tumours. Cancer Genetics and Cytogenetics. 67-73.
  • Show author(s) (1997). Complexity of 12q13-22 amplicon in liposarcoma: Microsatellite repeat analysis. Genes, Chromosomes and Cancer. 66-70.
  • Show author(s) (1996). Separate amplified regions encompassing CDK4 and MDM2 in human sarcomas. Genes, Chromosomes and Cancer. 254-259.
  • Show author(s) (1996). Reversal of the in vivo metastatic phenotype of human tumor cells by an anti-CAPL (mts-1) ribozyme. Cancer Research. 5490-5498.
  • Show author(s) (1995). Homozygous deletion frequency and expression levels of the CDKN2 gene in human sarcomas - relationship to amplification and mRNA levels of CDK4 and CCND1. British Journal of Cancer. 393-398.
  • Show author(s) (1995). Cloning and Characterization of Two Forms of Bovine Polymeric Immunoglobulin Receptor cDNA. DNA and Cell Biology. 251-256.
  • Show author(s) (1994). The protooncogene CHOP/GADD153, involved in growth arrest and DNA damage response, is amplified in a subset of human sarcomas. Cancer Genetics and Cytogenetics. 165-171.
  • Show author(s) (1994). Expression of the neuroectodermal intermediate filament nestin in human melanomas. Cancer Research. 354-356.
  • Show author(s) (1993). Mapping of amplification units in the q13-14 region of chromosome 12 in human sarcomas: Some amplica do not include MDM2. Cell growth & differentiation. 1065-1070.
  • Show author(s) (1992). Uptake of chylomicron remnant retinyl esters in human leukocytes in vivo. European J. Clin.. 229-234.
  • Show author(s) (1992). Levels of mm23 mRNA in metastatic malignant melanomas. Inverse correlation to disease progression. Cancer Research. 6088-6091.
Academic lecture
  • Show author(s) (2018). Clonal Evolution of Multiple Myeloma After Treatment with Novel Agents .
  • Show author(s) (2017). Sarcomas: Genomic Landscape and potential targets.
  • Show author(s) (2017). Detection of mutations in Multiple Myeloma during different stages of disease.
  • Show author(s) (2012). Personalized cancer medicine.
  • Show author(s) (2005). Genome-Wide Screening of DNA Copy Number and Chromosomal Alterations in Oral Squamous Cell Carcinomas by Micro Array Comparative Genomic Hybridizations.
  • Show author(s) (2005). Chromosomal Aberrations in Oral Squamous Cell Carcinoma by µArray Comparative Genomic Hybridizations.
  • Show author(s) (2005). Chromosomal Aberrations in Oral Squamous Cell Carcinoma by µArray Comparative Genomic Hybridizations.
  • Show author(s) (2002). Investigating the linearity of an RNA-amplification protocol using analysis of variance on data from cDNA microarray experiments.
  • Show author(s) (2000). Positional cloning of novel genes form 1q21, a region frequently over-represented in human malignancies.
  • Show author(s) (2000). Molecular profiling of sarcomas: Microarray analysis of osteosarcomas and isolation of three novel candidate genes from the 1q21 amplicon.
  • Show author(s) (1999). Microarray-based analysis of gene expression. New tools for the diagnosis of problem cases? Invited plenary talk at the annual meeting of the Scandinavian sarcoma group.
  • Show author(s) (1999). Microarray-based analysis of gene expression. New tools for the diagnosis of problem cases? Acta Othop. Scand. 70 suppl. 289: 24-25.
  • Show author(s) (1999). Global gene activity profiling by cDNA microarrays.
  • Show author(s) (1999). FISHing cDNAs from a frequently amplified region of chromosome 1 in sarcomas.
  • Show author(s) (1998). Malignanat peripheral neve sheath tumours show frequent alterations of chromosome band 9p21. Studies of CDKN2A and other genes of the pRB pathway.
  • Show author(s) (1998). Characterization of a novel amplicon at 1q21-q22 frequently observed in human sarcomas by Fluorescent in situ Hybridization (FISH).
  • Show author(s) (1997). The HMGIC gene is amplified, rearranged and overexpressed in a subset of human sarcomas.
  • Show author(s) (1997). The HMGIC gene is amplified, rearranged and overexpressed in a subset of human sarcomas.
  • Show author(s) (1997). HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas.
  • Show author(s) (1997). HMGIC, the gene for an architectural transcription factor, is amplified and rearranged in a subset of human sarcomas.
  • Show author(s) (1997). Fluorescent in situ hybridisation (FISH) in sarcoma research and diagnosis (Invited plenary lecture).
  • Show author(s) (1996). Mapping of Amplification Units Containing MDM2, CDK4 and SAS.
  • Show author(s) (1996). Chromosomal markers bearing chromosome 12 gene amplifications in adipose tissue tumours: FISH, molecular analysis and immunohistochemistry.
  • Show author(s) (1996). Chromosomal aberrations affecting cell cycle control genes in human sarcomas.
  • Show author(s) (1996). Characterisation of lq21q22 amplifications in human sarcomas by CGH and molecular analysis.
  • Show author(s) (1996). Characterisation of 1q21-q22 amplifications in human sarcomas by CGH and molecular analysis.
  • Show author(s) (1996). Amplification of MDM2, CDK4 and HMGIC in human sarcomas.
  • Show author(s) (1996). Amplification of MAR-Derived Sequences, Including HMGI-c, in Human Sarcomas.
  • Show author(s) (1996). A new method for sensitive detection and characterisation of malignant cells in blood and bone marrow of advanced breast cancer patients.
Abstract
  • Show author(s) (2019). Deep profiling of genetic aberrations and clonal evolution in follicular lymphoma. Blood. 20-20.
  • Show author(s) (2018). Whole-Exome and mRNA Sequencing of Multiple Myeloma Reveal Transformation to a More High-Risk and Proliferative Tumor at Relapse. Blood.
  • Show author(s) (2012). Identification of Fusion Transcripts in Colorectal Cancer by Combined RNA-seq and Exon Microarray Analyses. European Journal of Cancer. S121-S121.
  • Show author(s) (2010). Integrative analysis of genome-wide genetic and epigenetic changes in human osteosarcomas. European Journal of Cancer. 200-200.
  • Show author(s) (2010). Integrated analysis reveals overexpression of miRNA clusters in osteosarcomas. European Journal of Cancer. 206-207.
  • Show author(s) (2010). Characterisation of LSAMP, a novel candidate tumour suppressor gene in osteosarcomas. European Journal of Cancer. 169-169.
  • Show author(s) (2005). Genome-Wide Screening of DNA Copy Number and Chromosomal Alterations in Oral Squamous Cell Carcinomas by Micro Array Comparative Genomic Hybridizations. European Journal of Medical Genetics. 513-514.
Academic literature review
  • Show author(s) (2016). The ENCCA-WP7/EuroSarc/EEC/PROVABES/EURAMOS 3rd European Bone Sarcoma Networking Meeting/Joint Workshop of EU Bone Sarcoma Translational Research Networks; Vienna, Austria, September 24-25, 2015. Workshop Report. Clinical Sarcoma Research.
  • Show author(s) (2015). Personalized cancer therapy for soft tissue sarcomas: progress and pitfalls. Personalized Medicine. 593-602.
  • Show author(s) (2014). Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes. Science.
  • Show author(s) (2012). Workshop report on the European Bone Sarcoma Networking Meeting: integration of clinical trials with tumor biology. Journal of Adolescent and Young Adult Oncology.

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