Cardiovascular Research

Heart physiology

The interstitial matrix constitutes the framework for the individual cells of an organ as well as for the body as a whole. All hormones, nutrients and waste products going to and from the cells must pass the interstitial matrix.

During recent years it has become evident that the interstitial matrix is not merely a "passive" framework for the organs, but a structure which "actively" participates in the overall functions of the organs and therefore of the organism as a whole. The aim of our research group is to explore the function of the interstitial matrix by focusing on studies of the structure function relationship of the interstitial matrix and interstitial microvascular exchange under normal conditions as well as in experimental models of disease. Together, our studies address important physiological, biophysical and pathophysiological principles that could potentially form the basis from which medical treatment could be improved.