• E-postPaul.Hol@uib.no
  • Telefon+47 55 58 54 43+47 404 66 729
  • Besøksadresse
    Biomatlab, Laboratoriebygget, 7. etg.
    5021 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen

My on-going project is about improving performance and safety of clinical biomaterials. 

Bergen retrieval center for implants is collecting and analyzing joint prostheses that have failed due to aseptic loosening, often in combination with osteolysis or other immunological reactions.

I have specialised in trace element analysis, mainly on clinically related samples. Main elements of interest are Co, Cr, Zr, Mo, Ni and Ti measured by ICP-MS.

Utvalgte publikasjoner
  • Høl, Paul Johan; Gjerdet, Nils Roar; Jonung, Torbjörn. 2019. Corrosion and metal release from overlapping arterial stents under mechanical and electrochemical stress - An experimental study. Journal of The Mechanical Behavior of Biomedical Materials. 93: 31-35. doi: 10.1016/j.jmbbm.2019.02.001
  • Høl, Paul Johan; Kristoffersen, Einar Klæboe; Gjerdet, Nils Roar; Pellowe, Amanda. 2018. Novel nanoparticulate and ionic titanium antigens for hypersensitivity testing. International Journal of Molecular Sciences. 19:1101: 1-18. doi: 10.3390/ijms19041101
  • Kutzner, Ines; Halland, Geir; Høl, Paul Johan; Furnes, Ove; Gøthesen, Øystein; Figved, Wender; Ellison, Peter. 2017. Early aseptic loosening of a mobile-bearing total knee replacement: A case-control study with retrieval analyses. Acta Orthopaedica. 89: 77-83. Publisert 2017-11-06. doi: 10.1080/17453674.2017.1398012
  • Varsi, Kristin; Bolann, Bjørn Johan; Torsvik, Ingrid Kristin; Eik, Tina Constanse Rosvold; Høl, Paul Johan; Monsen, Anne Lise Bjørke. 2017. Impact of maternal selenium status on infant outcome during the first 6 months of life. Nutrients. 9. doi: 10.3390/nu9050486
  • Jonitz-Heincke, Anika; Tillmann, Jenny; Klinder, Annett; Krüger, Simone; Kretzer, Jan Philippe; Høl, Paul Johan; Paulus, Alexander C.; Bader, Rainer. 2017. The impact of metal ion exposure on the cellular behavior of human osteoblasts and PBMCs: In vitro analyses of osteolytic processes. Materials. 10:734: 1-15. Publisert 2017-07-03. doi: 10.3390/ma10070734
  • Grosse, Susann; Haugland, Hans Kristian; Lilleng, Peer Kåre; Ellison, Peter; Hallan, Geir; Høl, Paul Johan. 2015. Wear particles and ions from cemented and uncemented titanium-based hip prostheses - A histological and chemical analysis of retrieval material. Journal of Biomedical Materials Research. Part B - Applied biomaterials. 103: 709-717. doi: 10.1002/jbm.b.33243

Bergen Implant Retrieval center for Implants

The overall goal of our projects is to improve the performance and safety of orthopaedic and other surgical implants by a clinic-laboratory interaction.

Clinical performance of artificial materials can be predicted and improved by investigation of the retrieved devices that have been in clinical use, by a translational research approach, addressing biocompatibility and assessment of physical behavior.

Read more: https://www.researchgate.net/project/Bergen-Retrieval-Center-for-Implants