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Paul Johan Høls bilde

Paul Johan Høl

Senioringeniør, Forsker og leder av Biomatlab
  • E-postPaul.Hol@uib.no
  • Telefon+47 55 58 54 43+47 404 66 729
  • Besøksadresse
    Biomatlab, Laboratoriebygget, 7. etg.
    5021 Bergen
    Rom 
    7332
  • Postadresse
    Postboks 7804
    5020 Bergen

My on-going project is about improving performance and safety of clinical biomaterials. 

Bergen retrieval center for implants is collecting and analyzing joint prostheses that have failed due to aseptic loosening, often in combination with osteolysis or other immunological reactions.

I have specialised in trace element analysis, mainly on clinically related samples. Main elements of interest are Co, Cr, Zr, Mo, Ni and Ti measured by ICP-MS.

Google scholar: https://scholar.google.no/citations?user=NfSE-qUAAAAJ

  • Vis forfatter(e) 2021. Metallionenivåer i blod fra pasienter med metall-mot-metall-hofteprotese. Tidsskrift for Den norske legeforening. 31-36.
  • Vis forfatter(e) 2020. Strength of side-to-side and step-cut repairs in tendon transfers: biomechanical testing of porcine flexor tendons. Journal of Hand Surgery (European Volume). 1-5.
  • Vis forfatter(e) 2019. Strength of Pulvertaft modifications: tensile testing of porcine flexor tendons. Journal of Hand Surgery (European Volume). 795-799.
  • Vis forfatter(e) 2019. Metals in orthopaedic implants: Mechanical, chemical and biological properties of titanium and stainless steel implants .
  • Vis forfatter(e) 2019. Mekanismer for aseptisk løsning av sementert Spectron EF hoftestamme med Reflection kopp - en retrievalstudie.
  • Vis forfatter(e) 2019. Kontrollen av medisinske implantater kan bli bedre. Dagens medisin. 1 sider.
  • Vis forfatter(e) 2019. Impact of TiNbN wear particles on osteoblastic differentiation capacity and induction of inflammatory reactions.
  • Vis forfatter(e) 2019. Corrosion and metal release from overlapping arterial stents under mechanical and electrochemical stress - An experimental study. Journal of The Mechanical Behavior of Biomedical Materials. 31-35.
  • Vis forfatter(e) 2019. Cementing technique for primary knee arthroplasty: a scoping review. Acta Orthopaedica. 582-589.
  • Vis forfatter(e) 2018. Novel titanium antigens and assessment of immune activation.
  • Vis forfatter(e) 2018. Novel nanoparticulate and ionic titanium antigens for hypersensitivity testing. International Journal of Molecular Sciences. 1-18.
  • Vis forfatter(e) 2018. Metallnivå i blod hos pasienter med hofteprotese.
  • Vis forfatter(e) 2018. Label-free monitoring of uptake and toxicity of endoprosthetic wear particles in human cell cultures. International Journal of Molecular Sciences. 1-14.
  • Vis forfatter(e) 2018. An individual patient outcome tool for joint replacement patients.
  • Vis forfatter(e) 2018. An individual patient outcome tool for joint replacement patients. Studies in Health Technology and Informatics. 129-132.
  • Vis forfatter(e) 2017. The impact of metal ion exposure on the cellular behavior of human osteoblasts and PBMCs: In vitro analyses of osteolytic processes. Materials. 1-15.
  • Vis forfatter(e) 2017. Impact of maternal selenium status on infant outcome during the first 6 months of life. Nutrients.
  • Vis forfatter(e) 2017. Early aseptic loosening of a mobile-bearing total knee replacement: A case-control study with retrieval analyses. Acta Orthopaedica. 77-83.
  • Vis forfatter(e) 2016. Sporelementer i morsmelk.
  • Vis forfatter(e) 2016. Metallionenivåer i blod over 5 år med "Birmingham resurfacing" hofteprotese.
  • Vis forfatter(e) 2016. Investigation of mechanisms leading to early loosening of hip prostheses. A retrieval study of 27 failed cases of cemented Spectron EF stem in combination with Reflection acetabular cup.
  • Vis forfatter(e) 2016. Can clinical radiographs be used for large scale monitoring of polyethylene wear?
  • Vis forfatter(e) 2015. Wear particles and ions from cemented and uncemented titanium-based hip prostheses - A histological and chemical analysis of retrieval material. Journal of Biomedical Materials Research. Part B - Applied biomaterials. 709-717.
  • Vis forfatter(e) 2015. The effect of blood protein adsorption on cellular uptake of anatase TiO2 nanoparticles. International Journal of Nanomedicine. 687-695.
  • Vis forfatter(e) 2015. Novel titanium antigens cause lymphocyte proliferation and activation of monocyte/macrophage type cytokines.
  • Vis forfatter(e) 2015. Analyse av metallfrigjøring fra medisinske implantater.
  • Vis forfatter(e) 2014. Early aseptic loosening of a mobile-bearing total knee replacement – a retrieval analysis.
  • Vis forfatter(e) 2014. Early aseptic loosening of a mobile-bearing total knee replacement – A retrieval analysis.
  • Vis forfatter(e) 2014. Corrosion and Metal Release from Arterial Stents (Single and Stent in Stent) under Mechanical and Electrochemical Stress – an Experimental Study.
  • Vis forfatter(e) 2014. COMPARISON OF WEAR PARTICLE EXPOSURE AND TISSUE REACTIONS IN PATIENTS WITH CEMENTED AND UNCEMENTED TITANIUM HIP PROSTHESES THAT FAILED DUE TO OSTEOLYSIS. Bone & Joint Journal Orthopaedic Proceedings Supplement. 41-41.

Se fullstendig oversikt over publikasjoner i CRIStin.

Bergen Implant Retrieval center for Implants

The overall goal of our projects is to improve the performance and safety of orthopaedic and other surgical implants by a clinic-laboratory interaction.

Clinical performance of artificial materials can be predicted and improved by investigation of the retrieved devices that have been in clinical use, by a translational research approach, addressing biocompatibility and assessment of physical behavior.

Read more: https://www.researchgate.net/project/Bergen-Retrieval-Center-for-Implants

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