My on-going project is about improving performance and safety of clinical biomaterials.
Bergen retrieval center for implants is collecting and analyzing joint prostheses that have failed due to aseptic loosening, often in combination with osteolysis or other immunological reactions.
I have specialised in trace element analysis, mainly on clinically related samples. Main elements of interest are Co, Cr, Zr, Mo, Ni and Ti measured by ICP-MS.
- 2019. Corrosion and metal release from overlapping arterial stents under mechanical and electrochemical stress - An experimental study. Journal of The Mechanical Behavior of Biomedical Materials. 93: 31-35. doi: 10.1016/j.jmbbm.2019.02.001
- 2018. Novel nanoparticulate and ionic titanium antigens for hypersensitivity testing. International Journal of Molecular Sciences. 19:1101: 1-18. doi: 10.3390/ijms19041101
- 2017. Early aseptic loosening of a mobile-bearing total knee replacement: A case-control study with retrieval analyses. Acta Orthopaedica. 89: 77-83. Publisert 2017-11-06. doi: 10.1080/17453674.2017.1398012
- 2017. Impact of maternal selenium status on infant outcome during the first 6 months of life. Nutrients. 9. doi: 10.3390/nu9050486
- 2017. The impact of metal ion exposure on the cellular behavior of human osteoblasts and PBMCs: In vitro analyses of osteolytic processes. Materials. 10:734: 1-15. Publisert 2017-07-03. doi: 10.3390/ma10070734
- 2015. Wear particles and ions from cemented and uncemented titanium-based hip prostheses - A histological and chemical analysis of retrieval material. Journal of Biomedical Materials Research. Part B - Applied biomaterials. 103: 709-717. doi: 10.1002/jbm.b.33243
Bergen Implant Retrieval center for Implants
The overall goal of our projects is to improve the performance and safety of orthopaedic and other surgical implants by a clinic-laboratory interaction.
Clinical performance of artificial materials can be predicted and improved by investigation of the retrieved devices that have been in clinical use, by a translational research approach, addressing biocompatibility and assessment of physical behavior.