Neuro-SysMed Seminar November 12, 2025
Welcome to the Neuro-SysMed monthly seminar series! Join us at the auditorium in Armauer Hansens Hus at 11:30 - 13:00 (lunch from 11:30 - 12:00). Invited speaker is Professor Trygve Holmøy, University of Oslo/AHUS.
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Speaker: Professor Trygve Holmøy, Chief Consultant at the Department of Neurology, Akershus University Hospital, and Professor at the Institute of Clinical Medicine, University of Oslo.
Topic: Neurofilament Light Chain as a Disease Marker and Outcome Measure in Neurological Diseases
Hosts: Kjell Morten Myhr/Øivind Torkildsen from Neuro-SysMed's MS Node (external link)
Registration through this link. (external link) Deadline if you'd like to join the lunch is November 10 at 11.00
Place: The auditorium in Armauer Hansens Hus
When: November 12, 2025, at 11:30 - 13:00 (lunch 11:30 - 12:00).
Abstract:
Neurofilament light chain (NFL) is a biomarker of neuroaxonal degeneration. Emerging evidence suggests that the NFL reflects and predicts disease activity in neuroinflammatory and neurodegenerative diseases like multiple sclerosis (MS) and amyotrophic lateral sclerosis (ALS). Previous hurdles for the widespread use of NFL in clinical studies and management of patients, such as invasive sampling methods and limited assay availability, are being overcome through the development and validation of blood-based assays. However, whereas the NFL has proven useful as an outcome measure in clinical trials and a disease marker in epidemiological studies, its role in clinical practice is still debated. The talk will give an overview of current knowledge on the NFL in clinical research and practice.