Research

The Tronstad Lab investigates how metabolic aberrancies affect cell physiology, and how this may mediate disease development. Cell metabolism is affected by many factors in the microenvironment, including nutrients and signaling molecules, as well as intracellular processes such as signal transduction, gene transcription and enzymatic regulation. In this regard, metabolic processes are tightly connected with the mitochondrial organelle, which serves as a major energy producer (ATP), as well as a hub for pathways that senses and coordinates vital responses in the cell.

We have established state-of-the-art methodologies in our lab to investigate cell metabolism and mitochondrial biology, and their interactions with signaling pathways. Through collaboration with our partners in other research laboratories and in the clinic, our goal is to contribute with knowledge that may lead to new and effective biomarkers and strategies for disease surveillance, prevention and treatment.