Cell stress
Neuronal cell death

Fladmark Group

The group is using zebrafish as a model to study mechanisms of neurodegeneration.

Dagne Røise, UiB

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Our research is focused on mechanisms of how cellular stress leads to cell death and the ability of cells to protect themselves and neighboring cells from cell death. We are using zebrafish as an in vivo model to study cell death and protective mechanisms. Zebrafish models are emerging as a highly used model for human diseases. The development and function of organs are similar to humans and disease-related human genes have functional orthologs in zebrafish. Image: Zebrafish brain with neuronal mitochondria in red (Tg(NBTb-mitoDsRed2))