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Mathematical modeling and systems biology explain the evolutionary transition from a four-step to a two-step pathway for the synthesis of NAD from vitamin B3.
Researchers at the University of Florence had been looking for an new anti-cancer drug, when they realized the old rat poison called Vacor could be the answer to their searches
This week, researchers Nick Love, Nadine Pollak, Christian Dölle and Marc Niere from the Ziegler group report their discovery that the final step in the conversion of vitamin B3 to a molecule called NADP is critical for the embryonic development of animals.