- E-postAurora.Martinez@uib.no
- Telefon+47 55 58 64 27
- BesøksadresseJonas Lies vei 91
- PostadressePostboks 78045020 Bergen
Aurora Martinez er leder av forskningsgruppen Biorecognition som studerer sammenhengen mellom biomolekylær struktur og funksjon for å forstå og utvikle nye terapeutiske muligheter for genetiske sykdommer, spesielt neurometabolske forstyrrelser som fenylketonuri (PKU) og mangler i dopaminsyntese.
Aurora er også en partner i KG Jebsen-senteret for nevropsykiatriske lidelser. I tillegg er hun også en partner i prosjektet "Molekylær kontroll av Arc protein: Dekoding av en master regulator av synaptisk plastisitet og kognisjon", koordinert av Clive Bramham, som mottar støtte fra Toppforsk Programmet (NFR).
- 2021. Relevance of Electrostatics for the Interaction of Tyrosine Hydroxylase with Porous Silicon Nanoparticles. Molecular Pharmaceutics.
- 2020. Understanding the interaction between the co-chaperone DNAJC12 and tyrosine hydroxylase.
- 2020. Levalbuterol lowers the feedback inhibition by dopamine and delays misfolding and aggregation in tyrosine hydroxylase. Biochimie.
- 2020. G Protein-Gated Inwardly Rectifying Potassium Channel Subunit 3 Is Upregulated in Rat DRGs and Spinal Cord After Peripheral Nerve Injury . Journal of Pain Research. 419-429.
- 2019. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine-Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult Pah-Enu2 Mice. Nutrients.
- 2019. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine- Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult Pah-Enu2 Mice. Nutrients.
- 2019. Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proceedings of the National Academy of Sciences of the United States of America. 11229-11234.
- 2019. Phenylalanine hydroxylase variants interact with the co-chaperone DNAJC12. Human Mutation. 483-494.
- 2019. EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology. SLAS Discovery. 398-413.
- 2019. A Pharmacological Chaperone Therapy for Acute Intermittent Porphyria. Molecular Therapy.
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