Hjem
  • E-postAurora.Martinez@uib.no
  • Telefon+47 55 58 64 27
  • Besøksadresse
    Jonas Lies vei 91
  • Postadresse
    Postboks 7804
    5020 Bergen

Aurora Martinez er leder av forskningsgruppen Biorecognition som studerer sammenhengen mellom biomolekylær struktur og funksjon for å forstå og utvikle nye terapeutiske muligheter for genetiske sykdommer, spesielt neurometabolske forstyrrelser som fenylketonuri (PKU) og mangler i dopaminsyntese.

Aurora er også en partner i KG Jebsen-senteret for nevropsykiatriske lidelser. I tillegg er hun også en partner i prosjektet "Molekylær kontroll av Arc protein: Dekoding av en master regulator av synaptisk plastisitet og kognisjon", koordinert av Clive Bramham, som mottar støtte fra Toppforsk Programmet (NFR).

  • Van Vliet, Danique; van der Goot, Els; van Ginkel, Wiggert G; van Faassen, Martijn H J R; de Blaauw, Pim; Kema, Ido P.; Martinez, Aurora; Heiner-Fokkema, M Rebecca; van der Zee, Eddy A; van Spronsen, Francjan J. 2019. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine-Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult Pah-Enu2 Mice. Nutrients.
  • Van Vliet, Danique; van der Groot, Els; van Ginkel, Wiggert G; van Faassen, Martijn H J R; Blaauw, Pim; Kema, Ido P.; Martinez, Aurora; Heiner-Fokkema, Rebecca; van der Zee, Eddy A; van Spronsen, Francjan J. 2019. The Benefit of Large Neutral Amino Acid Supplementation to a Liberalized Phenylalanine- Restricted Diet in Adult Phenylketonuria Patients: Evidence from Adult Pah-Enu2 Mice. Nutrients.
  • Flydal, Marte Innselset; Alcorlo-Pagés, Martin; Johannessen, Fredrik Gullaksen; Martínez-Caballero, Siseth; Skjærven, Lars; Fernandez-Leiro, Rafael; Martinez, Aurora; Hermoso, Juan A. 2019. Structure of full-length human phenylalanine hydroxylase in complex with tetrahydrobiopterin. Proceedings of the National Academy of Sciences of the United States of America. 11229-11234.
  • K C, Kunwar Jung; Himmelreich, Nastassja; Prestegård, Karina Skjervheim; Shi, Tie-Jun; Scherer, Tanja; Ying, Ming; Jorge Finnigan, Ana; Thöny, Beat; Blau, Nenad; Martinez, Aurora. 2019. Phenylalanine hydroxylase variants interact with the co-chaperone DNAJC12. Human Mutation. 483-494.
  • Ji, Jianxiong; Xu, Ran; Ding, Kaikai; Bao, Guoqing; Zhang, Xin; Huang, Bin; Wang, Xinyu; Martinez, Aurora; Wang, Xiuying; Li, Gang; Miletic, Hrvoje; Thorsen, Frits; Bjerkvig, Rolf; Xiang, Lei; Han, Bo; Chen, Anjing; Li, Xingang; Wang, Jian. 2019. Long Noncoding RNA SChLAP1 Forms a Growth-Promoting Complex with HNRNPL in Human Glioblastoma through Stabilization of ACTN4 and Activation of NF-kappa B Signaling. Clinical Cancer Research. 6868-6881.
  • Brennecke, Philip; Rasina, Dace; Aubi Catevilla, Oscar; Herzog, Katja; Landskron, Johannes; Cautain, Bastien; Vicente, Francisca; Quintana, Jordi; Mestres, Jordi; Stechmann, Bahne; Ellinger, Bernhard; Brea, Jose; Kolanowski, Jacek L.; Pilarski, Radosław; Orzáez, Mar; Pineda-Lucena, Antonio; Laraia, Luca; Nami, Faranak; Zielenkiewicz, Piotr; Paruch, Kamil; Hansen, Espen; von Kries, Jens P.; Neuenschwander, Martin; Specker, Edgar; Bartunek, Petr; Šímová, Šárka; Leśnikowski, Zbigniew; Krauss, Stefan; Lehtiö, Lari; Bilitewski, Ursula; Brönstrup, Mark; Tasken, Kjetil; Jirgensons, Aigars; Lickert, Heiko; Clausen, Mads H.; Andersen, Jeanette hammer; Vicent, Maria J.; Genilloud, Olga; Martinez, Aurora; Nazaré, Marc; Fecke, Wolfgang; Gribbon, Philip. 2019. EU-OPENSCREEN: A novel collaborative approach to facilitate chemical biology. SLAS Discovery. 398-413.
  • Heggland, Erna Irene; Eichner, Christiane; Støve, Svein Isungset; Martinez, Aurora; Nilsen, Frank; Dondrup, Michael. 2019. A scavenger receptor B (CD36)-like protein is a potential mediator of intestinal heme absorption in the hematophagous ectoparasite Lepeophtheirus salmonis. Scientific Reports. 1-14.
  • Bustad, Helene J.; Toska, Karen; Schmitt, Caroline; Vorland, Marta; Skjærven, Lars; Kallio, Juha Pekka; Simonin, Sylvie; Lettéron, Philippe; Underhaug, Jarl; Sandberg, Sverre; Martinez, Aurora. 2019. A Pharmacological Chaperone Therapy for Acute Intermittent Porphyria. Molecular Therapy.
  • Ghorbani, Sadaf. 2018. On the protein complex between 14-3-3 proteins and tyrosine hydroxylase –Isoform differences and modulation of phosphorylation states.
  • Winn, Shelley R; Scherer, Tanja; Thöny, Beat; Ying, Ming; Martinez, Aurora; Weber, Sydney; Raber, Jacob; Harding, Cary O. 2018. Blood phenylalanine reduction corrects CNS dopamine and serotonin deficiencies and partially improves behavioral performance in adult phenylketonuric mice. Molecular Genetics and Metabolism. 6-20.

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