Hjem
Eystein Sverre Husebyes bilde

Eystein Sverre Husebye

Professor
  • E-postEystein.Husebye@uib.no
  • Telefon+47 55 97 30 78
  • Besøksadresse
    Jonas Liesvei 91
    5021 Bergen
  • Postadresse
    Postboks 7804
    5020 Bergen

Addison's sykdom (binyrebarksvikt)

Autoimmune polyendokrine syndromer

Hypoparathyroidisme

Hormonsykdommer

Bøker
  • Husebye, Eystein Sverre; Løvås, Kristian. 2017. Endokrinologi, en medisinsk lærebok. Gyldendal Akademisk. 245 sider. ISBN: 9788205502222.
Tidsskriftartikler
  • Eriksson, Daniel; Bacchetta, Rosa; Gunnarsson, Hörður Ingi; Chan, Alice; Barzaghi, Federica; Ehl, Stephan; Hallgren, Åsa; van Gool, Frederic; Sardh, Fabian; Lundqvist, Christina; Laakso, Saila M.; Rönnblom, Anders; Ekwall, Olov; Mäkitie, Outi; Bensing, Sophie; Husebye, Eystein Sverre; Anderson, Mark; Kämpe, Olle; Landegren, Nils. 2019. The autoimmune targets in IPEX are dominated by gut epithelial proteins. Journal of Allergy and Clinical Immunology. 144: 327-330.e8. doi: 10.1016/j.jaci.2019.02.031
  • Astor, Marianne; Zhu, Wendy; Björnsdóttir, Sigrídur; Bollerslev, Jens; Kämpe, Olle; Husebye, Eystein Sverre. 2018. Is there a need for an emergency card in hypoparathyroidism? Journal of Internal Medicine. 1-7. doi: 10.1111/joim.12865
  • Berglund, Agnethe; Cleemann, Line; Oftedal, Bergithe Eikeland; Holm, Kirsten; Husebye, Eystein Sverre; Gravholt, Claus H. 2018. 21-hydroxylase autoantibodies are more prevalent in Turner syndrome but without an association to the autoimmune polyendocrine syndrome type I. Clinical and Experimental Immunology. 1-5. doi: 10.1111/cei.13231
  • Bruserud, Øyvind; Costea, Daniela Elena; Laakso, Saila; Garty, Ben-Zion; Mathisen, Eirik; Mäkitie, Antti; Mäkitie, Outi; Husebye, Eystein Sverre. 2018. Oral tongue malignancies in Autoimmune polyendocrine syndrome type 1. Frontiers in Endocrinology. 9:463: 1-9. doi: 10.3389/fendo.2018.00463
  • Bruserud, Øyvind; Siddiqui, Huma; Cuida Marthinussen, Ileana Mihaela; Chen, Tsute; Jonsson, Roland; Oftedal, Bergithe Eikeland; Olsen, Ingar; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2018. Oral microbiota in autoimmune polyendocrine syndrome type 1. Journal of Oral Microbiology. 10:1442986: 1-10. doi: 10.1080/20002297.2018.1442986
  • Dahl, Sandra Rinne; Nermoen, Ingrid; Brønstad, Ingeborg; Husebye, Eystein Sverre; Løvås, Kristian; Thorsby, Per Medbøe. 2018. Assay of steroids by liquid chromatography-tandem mass spectrometry in monitoring 21-hydroxylase deficiency. Endocrine Connections. 7: 1542-1550. Publisert 2018-12-01. doi: 10.1530/EC-18-0453
  • Eriksson, Daniel; Dalin, Frida; Eriksson, Gabriel Nordling; Landegren, Nils; Bianchi, Matteo; Hallgren, Åsa; Dahlqvist, Per; Wahlberg, Jeanette; Ekwall, Olov; Winqvist, Ola; Catrina, Sergiu-Bogdan; Rönnelid, Johan; Hulting, Anna-Lena; Lindblad-Toh, Kerstin; Alimohammadi, Mohammad; Husebye, Eystein Sverre; Knappskog, Per; Pielberg, Gerli Rosengren; Bensing, Sophie; Kämpe, Olle. 2018. Cytokine autoantibody screening in the Swedish Addison Registry identifies patients with undiagnosed APS1. Journal of Clinical Endocrinology and Metabolism. 103: 179-186. doi: 10.1210/jc.2017-01957
  • Grytaas, Marianne; Sellevåg, Kjersti; Thordarson, Hrafnkell B; Husebye, Eystein Sverre; Løvås, Kristian; Larsen, Terje H. 2018. Cardiac magnetic resonance imaging of myocardial mass and fibrosis in primary aldosteronism. Endocrine Connections. 7: 413-424. doi: 10.1530/EC-18-0039
  • Hellesen, Alexander; Bratland, Eirik; Husebye, Eystein Sverre. 2018. Autoimmune Addison's disease – An update on pathogenesis. Annales d'Endocrinologie. 79: 157-163. doi: 10.1016/j.ando.2018.03.008
  • Hjellestad, Iren Drange; Softeland, Eirik; Husebye, Eystein Sverre; Jonung, Torbjörn. 2018. HbA1c predicts long-term postoperative mortality in patients with unknown glycemic status at admission for vascular surgery: An exploratory study. Journal of Diabetes. 1-11. doi: 10.1111/1753-0407.12873
  • Husebye, Eystein Sverre; Anderson, Mark S.; Kämpe, Olle. 2018. Autoimmune polyendocrine syndromes. New England Journal of Medicine. 378: 1132-1141. doi: 10.1056/NEJMra1713301
  • Penna-Martinez, Marissa; Filmann, Natalie; Bogdanou, Dimitra; Shoghi, Faroquhi; Huenecke, Sabine; Schubert, Ralf; Herrmann, Eva; Koehl, Ulrike; Husebye, Eystein Sverre; Badenhoop, Klaus. 2018. High-dose vitamin D in Addison's disease regulates T-cells and monocytes: A pilot trial. Nutrition - The International Journal of Applied and Basic Nutritional Sciences. 49: 66-73. doi: 10.1016/j.nut.2017.10.021
  • Sozaeva, Leila S.; Zilberman, Lubov I; Svetlova, Galina N; Andrianova, Ekaterina A; Kareva, Maria A.; Ivanova, Olga N.; Stepanova, Svetlana; Savelyeva, Larisa V; Mayorov, Alexander Y; Troshina, Ekaterina A; Orlova, Elizaveta M.; Husebye, Eystein Sverre; Peterkova, Valentina A. 2018. Clinical and immunological characteristics of diabetes mellitus in patients with autoimmune polyglandular syndrome type 1 in Russia. Sakharnyi Diabet. 21: 48-57. doi: 10.14341/DM9347
  • Ueland, Grethe Åstrøm; Husebye, Eystein Sverre. 2018. Metabolic complications in adrenal insufficiency. Frontiers of Hormone Research. 49: 104-113. doi: 10.1159/000486004
  • Ueland, Grethe Åstrøm; Methlie, Paal; Jøssang, Dag Eirik; Sagen, Jørn V.; Viste, Kristin; Thordarson, Hrafnkell B; Heie, Anette; Grytaas, Marianne; Løvås, Kristian; Biermann, Martin; Husebye, Eystein Sverre. 2018. Adrenal Venous Sampling for Assessment of Autonomous Cortisol Secretion. Journal of Clinical Endocrinology and Metabolism. 103: 4553-4560. doi: 10.1210/jc.2018-01198
  • Ueland, Grethe Åstrøm; Methlie, Paal; Øksnes, Marianne; Thordarson, Hrafnkell B; Sagen, Jørn V.; Kellmann, Ralf; Mellgren, Gunnar; Ræder, Maria B; Dahlqvist, Per; Dahl, Sandra Rinne; Thorsby, Per Medbøe; Løvås, Kristian; Husebye, Eystein Sverre. 2018. The short cosyntropin test revisited: new normal reference range using LC-MS/MS. Journal of Clinical Endocrinology and Metabolism. 103: 1696-1703. doi: 10.1210/jc.2017-02602
  • Vakkilainen, Svetlana; Makitie, Riikka; Klemetti, Paula; Valta, Helena; Taskinen, Mervi; Husebye, Eystein Sverre; Mäkitie, Outi. 2018. A wide spectrum of autoimmune manifestations and other symptoms suggesting immune dysregulation in patients with cartilage-hair hypoplasia. Frontiers in Immunology. 9. doi: 10.3389/fimmu.2018.02468
  • Fishman, Dmytro; Kisand, Kai; Hertel, Christina; Rothe, Mike; Remm, Anu; Pihlap, Maire; Adler, Priit; Vilo, Jaak; Peet, Aleksandr; Meloni, Antonella; Podkrajšek, Katarina Trebušak; Battelino, Tadej; Bruserud, Øyvind; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Kluger, Nicolas; Krohn, Kai; Ranki, Annamari; Peterson, Hedi; Hayday, Adrian; Peterson, Part. 2017. Autoantibody repertoire in APECED patients targets two distinct subgroups of proteins. Frontiers in Immunology. 8. doi: 10.3389/fimmu.2017.00976
  • Fishman, Dmytro; Kisand, Kai; Hertel, Christina; Rothe, Mike; Remm, Anu; Pihlap, Maire; Adler, Priit; Vilo, Jaak; Peet, Aleksandr; Meloni, Antonella; Podkrajšek, Katarina Trebušak; Battelino, Tadej; Bruserud, Øyvind; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Kluger, Nicolas; Krohn, Kai; Ranki, Annamari; Peterson, Hedi; Hayday, Adrian; Peterson, Pärt. 2017. Autoantibody Repertoire in APECED Patients Targets Two Distinct Subgroups of Proteins. Frontiers in Immunology. 8. doi: 10.3389/fimmu.2017.00976
  • Grytaas, Marianne Aardal; Strømsøy, Siri S.; Rørvik, Jarle; Arnes, Jarle; Heie, Anette; Arnesen, Thomas; Jørstad, Melissa Davidsen; Nedrebø, Bjørn Gunnar; Jøssang, Dag Eirik; Jensen, Dag Kjartan; Rørvik, Håvard D.; Sagen, Jørn V.; Mellgren, Gunnar; Thordarson, Hrafnkell B; Husebye, Eystein Sverre; Løvås, Kristian. 2017. Clinical Characteristics and Long-Term Outcome of Primary Aldosteronism in a Norwegian Population. Hormone and Metabolic Research. 49: 838-846. doi: 10.1055/s-0043-118909
  • Nermoen, Ingrid; Husebye, Eystein Sverre; Myhre, Anne Margrethe; Løvås, Kristian. 2017. Klassisk medfødt binyrebarkhyperplasi. Tidsskrift for Den norske legeforening. 137: 540-543. doi: 10.4045/tidsskr.16.0376
  • Orlova, Elizaveta M.; Sozaeva, Leila S.; Kareva, Maria A.; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Breivik, Lars Ertesvåg; Zakharova, Ekaterina Y.; Ivanova, Olga N.; Kämpe, Olle; Dedov, Ivan I.; Knappskog, Per; Peterkova, Valentina A.; Husebye, Eystein Sverre. 2017. Expanding the Phenotypic and Genotypic Landscape of Autoimmune Polyendocrine Syndrome Type 1. Journal of Pediatric Endocrinology & Metabolism (JPEM). 102: 3546-3556. doi: 10.1210/jc.2017-00139
  • Smith-Anttila, Casey J.A.; Bensing, Sophie; Alimohammadi, Mohammad; Dalin, Frida; Oscarson, Mikael; Zhang, Ming-Dong; Perheentupa, Jaakko; Husebye, Eystein Sverre; Gustafsson, Jan; Björklund, Peyman; Fransson, Anette; Nordmark, Gunnel; Rönnblom, Lars; Meloni, Antonella; Scott, Rodney J.; Hökfelt, Tomas; Crock, Patricia A.; Kämpe, Olle. 2017. Identification of endothelin-converting enzyme-2 as an autoantigen in autoimmune polyendocrine syndrome type 1. Autoimmunity. 50: 223-231. doi: 10.1080/08916934.2017.1332183
  • Sævik, Åse Bjorvatn; Åkerman, Anna Karin; Grønning, Kaja; Nermoen, Ingrid; Valland, Susanna Fonneland; Finnes, Trine Elisabeth; Isaksson, Magnus; Dahlqvist, Per; Bergthórsdóttir, Ragnhildur; Ekwall, Olov; Skov, Jakob; Nedrebø, Bjørn Gunnar; Hulting, Anne Lena; Wahlberg, Jeanette; Svartberg, Johan; Höybye, Charlotte; Bleskestad, Inger Hjørdis; Jørgensen, Anders Palmstrøm; Kämpe, Olle; Øksnes, Marianne; Bensing, Sophie; Husebye, Eystein Sverre. 2017. Clues for early detection of autoimmune Addison's disease - myths and realities. Journal of Internal Medicine. 283: 190-199. doi: 10.1111/joim.12699
  • Ueland, Grethe Åstrøm; Methlie, Paal; Kellmann, Ralf; Bjørgaas, Marit Ragnhild Rokne; Åsvold, Bjørn Olav; Thorstensen, Ketil; Kelp, Oskar; Thordarson, Hrafnkell B; Mellgren, Gunnar; Løvås, Kristian; Husebye, Eystein Sverre. 2017. Simultaneous assay of cortisol and dexamethasone improved diagnostic accuracy of the dexamethasone suppression test. European Journal of Endocrinology. 176: 705-713. doi: 10.1530/EJE-17-0078
  • Abramson, Jakub; Husebye, Eystein Sverre. 2016. Autoimmune regulator and self-tolerance - molecular and clinical aspects. Immunological Reviews. 271: 127-140. doi: 10.1111/imr.12419
  • Astor, Marianne; Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik Fink; Evang, Johan Arild; Fossum, Jan Christian; Fougner, Kristian J; Holte, Synnøve Emblem; Lima, Kari; Moe, Ragnar Bekkhus; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn Gunnar; Svartberg, Johan; Husebye, Eystein Sverre. 2016. Epidemiology and health-related quality of life in hypoparathyroidism in Norway. Journal of Clinical Endocrinology and Metabolism. 101: 3045-3053. doi: 10.1210/jc.2016-1477
  • Bensing, Sophie; Hulting, Anna-Lena; Husebye, Eystein Sverre; Kämpe, Olle; Løvås, Kristian. 2016. Management of endocrine disease - Epidemiology, quality of life and complications of primary adrenal insufficiency: A review. European Journal of Endocrinology. 175: R107-R116. doi: 10.1530/EJE-15-1242
  • Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Landegren, Nils; Erichsen, Martina Moter; Bratland, Eirik; Lima, Kari; Jørgensen, Anders Palmstrøm; Myhre, Anne Grethe; Svartberg, Johan; Fougner, Kristian J; Bakke, Åsne; Nedrebø, Bjørn Gunnar; Mella, Bjarne; Breivik, Lars Ertesvåg; Viken, Marte K; Knappskog, Per; Cuida Marthinussen, Ileana Mihaela; Løvås, Kristian; Kämpe, Olle; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2016. A longitudinal follow-up of autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 101: 2975-2983. doi: 10.1210/jc.2016-1821
  • Bruserud, Øyvind; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre. 2016. AIRE-mutations and autoimmune disease. Current Opinion in Immunology. 43: 8-15. doi: 10.1016/j.coi.2016.07.003
  • Edvardsen, Kine Susann Waade; Hellesen, Alexander; Husebye, Eystein Sverre; Bratland, Eirik. 2016. Analysis of cellular and humoral immune responses against cytomegalovirus in patients with autoimmune Addison's disease. Journal of Translational Medicine. 14:68. doi: 10.1186/s12967-016-0822-z
  • Hetemäki, Iivo; Jarva, Hanna; Kluger, Nicolas; Baldauf, Hanna-Mari; Laakso, Sini; Bratland, Eirik; Husebye, Eystein Sverre; Kisand, Kai; Ranki, Annamari; Peterson, Pärt; Arstila, T.Petteri. 2016. Anticommensal responses are associated with regulatory T cell defect in autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy patients. Journal of Immunology. 196: 2955-2964. doi: 10.4049/jimmunol.1500301
  • Hjellestad, Iren Drange; Søfteland, Eirik; Nilsen, Roy Miodini; Husebye, Eystein Sverre; Jonung, Torbjörn. 2016. Abdominal aortic aneurysms - glycaemic status and mortality. Journal of diabetes and its complications. 30: 438-443. doi: 10.1016/j.jdiacomp.2015.12.015
  • Landegren, Nils; Sharon, Donald; Freyhult, Eva; Hallgren, Åsa; Eriksson, Daniel; Edqvist, Per-Henrik D.; Bensing, Sophie; Wahlberg, Jeanette; Nelson, Lawrence M.; Gustafsson, Jan; Husebye, Eystein Sverre; Anderson, Mark S.; Snyder, Michael; Kämpe, Olle. 2016. Proteome-wide survey of the autoimmune target repertoire in autoimmune polyendocrine syndrome type 1. Scientific Reports. 6. doi: 10.1038/srep20104
  • Pazderska, Agnieszka; Oftedal, Bergithe Eikeland; Napier, Catherine M.; Ainsworth, Holly F.; Husebye, Eystein Sverre; Cordell, Heather J.; Pearce, Simon H.S.; Mitchell, Anna L. 2016. A variant in the BACH2 gene is associated with susceptibility to autoimmune addison's disease in humans. Journal of Clinical Endocrinology and Metabolism. 101: 3865-3869. doi: 10.1210/jc.2016-2368
  • Simunkova, Katerina; Husebye, Eystein Sverre. 2016. Adrenal insufficiency therapy: How to keep the balance between good quality of life and low risk for long-term side effects? Frontiers of Hormone Research. 46: 196-210. doi: 10.1159/000443920
  • Simunkova, Katerina; Jovanovic, Nevena; Rostrup, Espen; Methlie, Paal; Øksnes, Marianne; Nilsen, Roy Miodini; Hennø, Hanne; Tilseth, Mira; Godang, Kristin; Kovac, Ana; Løvås, Kristian; Husebye, Eystein Sverre. 2016. Effect of a pre-exercise hydrocortisone dose on short-term physical performance in female patients with primary adrenal failure. European Journal of Endocrinology. 174: 97-105. doi: 10.1530/EJE-15-0630
  • Astor, Marianne; Løvås, Kristian; Wolff, Anette Susanne Bøe; Nedrebø, Bjørn Gunnar; Bratland, Eirik; Steen-Johnsen, Jon; Husebye, Eystein Sverre. 2015. Hypomagnesemia and functional hypoparathyroidism due to novel mutations in the Mg-channel TRPM6. Endocrine Connections. 4: 215-222. doi: 10.1530/EC-15-0066
  • Björnsdottir, Sigridur; Øksnes, Marianne; Isaksson, Magnus; Methlie, Paal; Nilsen, Roy Miodini; Hustad, Simon Steinar; Kämpe, Olle; Hulting, Anna-Lena; Husebye, Eystein Sverre; Løvås, Kristian; Nyström, Thomas; Bensing, Sophie. 2015. Circadian hormone profiles and insulin sensitivity in patients with Addison's disease: a comparison of continuous subcutaneous hydrocortisone infusion with conventional glucocorticoid replacement therapy. Clinical Endocrinology. 83: 28-35. doi: 10.1111/cen.12670
  • Bruserud, Øyvind; Husebye, Eystein Sverre. 2015. En mann i 30-årene med diabetes og vitiligo. Tidsskrift for Den norske legeforening. 135: 763-766. doi: 10.4045/tidsskr.14.1113
  • Chuprin, Anna; Avin, Ayelet; Goldfarb, Yael; Herzig, Yonatan; Levi, Ben; Jacob, Adi; Sela, Asaf; Katz, Shir; Grossman, Moran; Guyon, Clotilde; Rathaus, Moran; Cohen, Haim Y.; Sagi, Irit; Giraud, Matthieu; McBurney, Michael W.; Husebye, Eystein Sverre; Abramson, Jakub. 2015. The deacetylase Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nature Immunology. 16: 737-745. doi: 10.1038/ni.3194
  • Edvardsen, Kine Susann Waade; Bjånesøy, Trine Elholm; Hellesen, Alexander; Breivik, Lars Ertesvåg; Bakke, Marit; Husebye, Eystein Sverre; Bratland, Eirik. 2015. Peripheral blood cells from patients with autoimmune Addison's disease poorly respond to interferons in vitro, despite elevated serum levels of interferon-inducible chemokines. Journal of Interferon and Cytokine Research. 35: 759-770. doi: 10.1089/jir.2014.0171
  • Falorni, Alberto; Bini, Vittorio; Betterle, Corrado; Brozzetti, Annalisa; Castaño, Luis; Fichna, Marta; Kämpe, Olle; Mellgren, Gunnar; Peterson, Pärt; Chen, Shu; Rönnelid, Johan; Seissler, Jochen; Tiberti, Claudio; Uibo, Raivo; Yu, Liping; Lernmark, Ake; Husebye, Eystein Sverre. 2015. Determination of 21-hydroxylase autoantibodies: Inter-laboratory concordance in the Euradrenal International Serum Exchange Program. Clinical Chemistry and Laboratory Medicine. 53: 1761-1770. doi: 10.1515/cclm-2014-1106
  • Fichna, Marta; Zurawek, Magdalena; Bratland, Eirik; Husebye, Eystein Sverre; Kasperlik-Zaluska, Anna; Czarnocka, Barbara; Januszkiewicz-Lewandowska, Danuta; Nowak, Jerzy. 2015. Interleukin-2 and subunit alpha of its soluble receptor in autoimmune Addison's disease - An association study and expression analysis. Autoimmunity. 48: 100-107. doi: 10.3109/08916934.2014.976628
  • Landegren, Nils; Sharon, Donald; Shum, Anthony K.; Khan, Imran S.; Fasano, Kayla J.; Hallgren, Åsa; Kampf, Caroline; Freyhult, Eva; Ardesjö-Lundgren, Brita; Alimohammadi, Mohammad; Rathsman, Sandra; Ludvigsson, Jonas F.; Lundh, Dan; Motrich, Ruben; Rivero, Virginia; Fong, Lawrence; Giwercman, Aleksander; Gustafsson, Jan; Perheentupa, Jaakko; Husebye, Eystein Sverre; Anderson, Mark S.; Snyder, Michael; Kämpe, Olle. 2015. Transglutaminase 4 as a prostate autoantigen in male subfertility. Science Translational Medicine. 7. doi: 10.1126/scitranslmed.aaa9186
  • Mitchell, Anna L.; Wolff, Anette Susanne Bøe; MacArthur, Katie; Weaver, Jolanta U.; Vaidya, Bijay; Bensing, Sophie; Erichsen, Martina Moter; Darlay, Rebecca; Husebye, Eystein Sverre; Cordell, Heather J.; Pearce, Simon H.S.; Ekwall, O; Hulting, AL; Kockum, I; Kämpe, O; Nordling-Eriksson, G; Wahlberg-Topp, J. 2015. Linkage analysis in autoimmune Addison's disease: NFATC1 as a potential novel susceptibility locus. PLOS ONE. 10:e0123550. doi: 10.1371/journal.pone.0123550
  • Oftedal, Bergithe Eikeland; Hellesen, Alexander; Erichsen, Martina Moter; Bratland, Eirik; Vardi, Ayelet; Perheentupa, Jaakko; Kemp, E. Helen; Fiskerstrand, Torunn; Viken, Marte K; Weetman, Anthony P.; Fleishman, Sarel J.; Banka, Siddharth; Newman, William G.; Sewell, William A. Carrock; Sozaeva, Leila S.; Zayats, Tetyana; Haugarvoll, Kristoffer; Orlova, Elizaveta M.; Haavik, Jan; Johansson, Stefan; Knappskog, Per; Løvås, Kristian; Wolff, Anette Susanne Bøe; Abramson, Jakub; Husebye, Eystein Sverre. 2015. Dominant mutations in the autoimmune regulator AIRE are associated with common organ-specific autoimmune diseases. Immunity. 42: 1185-1196. doi: 10.1016/j.immuni.2015.04.021
  • Quinkler, Marcus; Dahlqvist, Per; Husebye, Eystein Sverre; Kämpe, Olle. 2015. A European Emergency Card for adrenal insufficiency can save lives. European journal of internal medicine. 26: 75-76. doi: 10.1016/j.ejim.2014.11.006
  • Wolff, Anette Susanne Bøe; Mitchell, Anna L.; Cordell, Heather J.; Short, Andrea; Skinningsrud, Beate; Ollier, William; Badenhoop, Klaus; Meyer, Gesine; Falorni, Alberto; Kämpe, Olle; Undlien, Dag Erik; Pearce, Simon H.S.; Husebye, Eystein Sverre. 2015. CTLA-4 as a genetic determinant in autoimmune Addison's disease. Genes and Immunity. 16: 430-436. doi: 10.1038/gene.2015.27
  • Bjånesøy, Trine Elholm; Kulle, Bettina; Bratland, Eirik; Reiner, Andrew Henry; Islam, Shahinul; Husebye, Eystein Sverre; Bakke, Marit. 2014. Altered DNA methylation profile in Norwegian patients with Autoimmune Addison's Disease. Molecular Immunology. 59: 208-216. doi: 10.1016/j.molimm.2014.02.018
  • Breivik, Lars Ertesvåg; Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Orlova, Elizaveta M.; Husebye, Eystein Sverre. 2014. A novel cell-based assay for measuring neutralizing autoantibodies against type I interferons in patients with autoimmune polyendocrine syndrome type 1. Clinical Immunology. 153: 220-227. doi: 10.1016/j.clim.2014.04.013
  • Brønstad, Ingeborg; Breivik, Lars Ertesvåg; Methlie, Paal; Wolff, Anette Susanne Bøe; Bratland, Eirik; Nermoen, Ingrid; Løvås, Kristian; Husebye, Eystein Sverre. 2014. Functional studies of novel CYP21A2 mutations detected in Norwegian patients with congenital adrenal hyperplasia. Endocrine Connections. 15: 67-74. doi: 10.1530/EC-14-0032
  • Brønstad, Ingeborg; Skinningsrud, Beate; Bratland, Eirik; Løvås, Kristian; Undlien, Dag Erik; Husebye, Eystein Sverre; Wolff, Anette Susanne Bøe. 2014. CYP21A2 polymorphisms in patients with autoimmune Addison's disease, and linkage disequilibrium to HLA risk alleles. European Journal of Endocrinology. 171: 743-750. doi: 10.1530/EJE-14-0432
  • Dawoodji, Amina; Chen, Ji-Li; Shepherd, Dawn; Dalin, Frida; Tarlton, Andrea; Alimohammadi, Mohammad; Penna-Martinez, Marissa; Meyer, Gesine; Mitchell, Anna L.; Gan, Earn H.; Bratland, Eirik; Bensing, Sophie; Husebye, Eystein Sverre; Pearce, Simon H.; Badenhoop, Klaus; Kämpe, Olle; Cerundolo, Vincenzo. 2014. High frequency of cytolytic 21-hydroxylase-specific CD8+ T cells in autoimmune Addison's disease patients. Journal of Immunology. 193: 2118-2126. doi: 10.4049/jimmunol.1400056
  • Hegvik, Tor-Arne; Husebye, Eystein Sverre; Haavik, Jan. 2014. Autoantibodies targeting neurotransmitter biosynthetic enzymes in attention-deficit/hyperactivity disorder (ADHD). European Child and Adolescent Psychiatry. 23: 115-117. doi: 10.1007/s00787-013-0429-3
  • Hellesen, Richard Alexander; Edvardsen, Kine Susann Waade; Breivik, Lars Ertesvåg; Husebye, Eystein Sverre; Bratland, Eirik. 2014. The effect of types I and III interferons on adrenocortical cells and its possible implications for autoimmune Addison's disease. Clinical and Experimental Immunology. 176: 351-362. doi: 10.1111/cei.12291
  • Husebye, Eystein Sverre; Allolio, Bruno; Arlt, Wiebke; Badenhoop, Klaus; Bensing, Sophie; Betterle, Corrado; Falorni, Alberto; Gan, Earn H.; Hulting, Anna-Lena; Kasperlik-Zaluska, Anna A.; Kämpe, Olle; Løvås, Kristian; Meyer, Gesine; Pearce, Simon H. 2014. Consensus statement on the diagnosis, treatment and follow-up of patients with primary adrenal insufficiency. Journal of Internal Medicine. 275: 104-115. doi: 10.1111/joim.12162
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  • Brønstad, Ingeborg; Wolff, Anette Susanne Bøe; Løvås, Kristian; Knappskog, Per; Husebye, Eystein Sverre. 2011. Genome-wide copy number variation (CNV) in patients with autoimmune Addison's disease. BMC Medical Genetics. 12. 6 sider. doi: 10.1186/1471-2350-12-111
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  • Lima, Kari; Abrahamsen, Tore G; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Alimohammadi, Mohammad; Kämpe, Olle; Følling, Ivar. 2011. Hypoparathyroidism and autoimmunity in the 22q11.2 deletion syndrome. European Journal of Endocrinology. 165: 345-352. doi: 10.1530/EJE-10-1206
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  • Smith, Casey J.A.; Oscarson, Mikael; Rönnblom, Lars; Alimohammadi, Mohammad; Perheentupa, Jaako; Husebye, Eystein Sverre; Gustafsson, Jan; Nordmark, Gunnel; Meloni, Antonella; Crock, Patricia A.; Kämpe, Olle; Bensing, Sophie. 2011. TSGA10 – A target for autoantibodies in autoimmune polyendocrine syndrome Type 1 and systemic lupus erythematosus. Scandinavian Journal of Immunology. 73: 147-153. doi: 10.1111/j.1365-3083.2010.02486.x
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  • Cheng, M; Fan, U; Grewal, N; Barnes, M; Mehta, A; Taylor, S; Husebye, Eystein Sverre; Murphy, EJ; Anderson, MS. 2010. Acquired Autoimmune Polyglandular Syndrome, Thymoma, and an AIRE Defect. New England Journal of Medicine. 362: 764-766.
  • Erichsen, Eva Martina Moter; Husebye, Eystein Sverre; Michelsen, Trond Melbye; Dahl, Alv A; Løvås, Kristian. 2010. Sexuality and Fertility in Women with Addison's Disease. Journal of Clinical Endocrinology and Metabolism. 95: 4354-4360. doi: 10.1210/jc.2010-0445
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  • Hallgren, Åsa; Pourmousa, Mina; Skov, Jakob; Nilsson, Thomas; Gustafsson, Jan; Husebye, Eystein Sverre; Perheentupa, Jaako; Hagforsen, Eva; Rorsman, Fredrik; Kämpe, Olle. 2010. Immunoreactivity against kidney collecting ducts in patients with autoimmune polyendocrine syndrome type 1 and systemic hypertension. Endocrine journal. 57: S641-S641.
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  • Nermoen, Ingrid; Husebye, Eystein; Svartberg, Johan; Løvås, K. 2010. Subjective health status in men and women with congenital adrenal hyperplasia: a population-based survey in Norway. European Journal of Endocrinology. 163: 453-459. doi: 10.1530/EJE-10-0284
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  • Skinningsrud, Beate; Lie, Benedicte; Husebye, Eystein S; Kvien, Tore K; Førre, Øystein; Flatø, Berit; Stormyr, Alice; Joner, Geir; Njølstad, Pål R; Egeland, Thore; Undlien, Dag E. 2010. A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-cyclic citrullinated peptide antibody negative rheumatoid arthritis. Annals of the Rheumatic Diseases. 69: 1471-1474. doi: 10.1136/ard.2009.114934
  • Sørheim, Jan Inge; Husebye, Eystein Sverre; Nedrebø, Bjørn Gunnar; Svarstad, Einar; Lind, Jonas Anders; Boman, Helge; Løvås, Kristian. 2010. Phenotypic Variation in a Large Family with Autosomal Dominant Hypocalcaemia. Hypertension in Pregnancy. 74: 399-405. doi: 10.1159/000303188
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  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Kisand, Kai; Ersvær, Elisabeth; Lima, Kari; Husebye, Eystein Sverre. 2010. Flow cytometry study of blood cell subtypes reflects autoimmune and inflammatory processes in autoimmune polyendocrine syndrome type I. Scandinavian Journal of Immunology. 71: 459-467. doi: 10.1111/j.1365-3083.2010.02397.x
  • Alimohammadi, Mohammad; Dubois, Noémie; Sköldberg, Filip; Hallgren, Åsa; Tardivel, Isabelle; Hedstrand, Håkan; Haavik, Jan; Husebye, Eystein Sverre; Gustafsson, Jan; Rorsman, Fredrik; Meloni, Antonella; Janson, Christer; Vialettes, Bernard; Kajosaari, Merja; Egner, William; Sargur, Ravishankar; Pontén, Fredrik; Amoura, Zahir; Grimfeld, Alain; De Luca, Filippo; Betterle, Corrado; Perheentupa, Jaakko; Kämpe, Olle; Carel, Jean-Claude. 2009. Pulmonary autoimmunity as a feature of autoimmune polyendocrine syndrome type 1 and identification of KCNRG as a bronchial autoantigen. Proceedings of the National Academy of Sciences of the United States of America. 106: 4396-4411. doi: 10.1073/pnas.0809986106
  • Bratland, Eirik; Bredholt, Geir; Mellgren, Gunnar; Knappskog, Per; Mozes, Edna; Husebye, Eystein Sverre. 2009. The purification and application of biologically active recombinant steroid cytochrome P450 21-hydroxylase: The major autoantigen in autoimmune Addison's disease. Journal of Autoimmunity. 33: 58-67. doi: 10.1016/j.jaut.2009.02.018
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  • Løvås, Kristian; Curran, Suzanne; Øksnes, Marianne; Husebye, Eystein Sverre; Huppert, Felicia A.; Chatterjee, V.K. 2009. Development of a Disease-Specific Quality of Life Questionnaire in Addison’s Disease. Journal of Clinical Endocrinology and Metabolism. Publisert 2009-12-16. doi: 10.1210/jc.2009-1711
  • Løvås, Kristian; Gjesdal, Clara G; Christensen, Monica; Wolff, Anette; Almas, B; Almås, Bjørg; Svartberg, Johan; Fougner, Kristian J; Syversen, Unni; Bollerslev, Jens; Falch, Jan A; Falch, Jan Arvid; Hunt, Penelope; Chatterjee, V Krishna; Husebye, Eystein S. 2009. Glucocorticoid replacement therapy and pharmacogenetics in Addison's disease: effects on bone. European Journal of Endocrinology. 160: 993-1002. doi: 10.1530/EJE-08-0880
  • Løvås, Kristian; Lovas, K; Røst, Therese Halvorsen; Rost, TH; Skorve, Jon; Ulvik, Rune Johan; Gudbrandsen, Oddrun Anita; Bohov, Pavol; Wensaas, Andreas J.; Rustan, Arild C.; Berge, Rolf Kristian; Husebye, Eystein Sverre. 2009. Tetradecylthioacetic acid attenuates dyslipidaemia in male patients with type 2 diabetes mellitus, possibly by dual PPAR-alpha/delta activation and increased mitochondrial fatty acid oxidation. Diabetes, obesity and metabolism. 11: 304-314. doi: 10.1111/j.1463-1326.2008.00958.x
  • Magitta, Ng'weina Francis; Wolff, Anette Susanne Bøe; Johansson, Stefan; Skinningsrud, Beate; Lie, Benedicte A; Myhr, Kjell-Morten; Undlien, Dag Erik; Joner, Geir; Njølstad, Pål Rasmus; Kvien, Tore K.; Førre, Øystein; Knappskog, Per Morten; Husebye, Eystein Sverre. 2009. A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes. Genes and Immunity. 10: 120-124. doi: 10.1038/gene.2008.85
  • Mitchell, AL; Cordell, HJ; Soemedi, R; Owen, K; Skinningsrud, Beate; Wolff, AB; Ericksen, M; Undlien, Dag Erik; Husebye, Eystein; Pearce, SH. 2009. Programmed death ligand 1 (PD-L1) gene variants contribute to autoimmune Addison's disease and Graves' disease susceptibility. Journal of Clinical Endocrinology and Metabolism. 94: 5139-5145. doi: 10.1210/jc.2009-1404
  • Mitchell, Anna L.; Cordell, Heather J.; Soemedi, Rachel; Skinningsrud, Beate; Wolff, Anette Susanne Bøe; Ericksen, Martina; Undlien, Dag; Husebye, Eystein Sverre; Pearce, Simon H. 2009. Programmed Death Ligand 1 (PD-L1) Gene Variants Contribute to Autoimmune Addison’s Disease and Graves’ Disease Susceptibility. Journal of Clinical Endocrinology and Metabolism. 94: 5139-5145. doi: 10.1210/jc.2009-1404
  • Nermoen, Ingrid; Følling, Ivar; Vegge, Kjetil; Larmo, Arne; Nedrebø, Bjørn Gunnar; Husebye, Eystein Sverre; Løvås, Kristian. 2009. Two adults with adrenal myelolipoma and 21-hydroxylase deficiency. Clinical Medicine : Case Reports. 4 sider. Publisert 2009-08-13. doi: 10.1155/2009/916891
  • Skinningsrud, Beate; Husebye, Einar; Husebye, Eystein Sverre; Gilfillan, Gregor D; Frengen, Eirik; Erichsen, Aage; Gervin, Kristina; Gervin, Kristina; Ormerod, Eli; Ormerød, Eli; Egeland, Thore; Egeland, Thore; Undlien, Dag E. 2009. X-Linked Congenital Adrenal Hypoplasia with Hypogonadotropic Hypogonadism Caused by an Inversion Disrupting a Conserved Noncoding Element Upstream of the NR0B1 (DAX1) Gene. Journal of Clinical Endocrinology and Metabolism. 94: 4086-4093. doi: 10.1210/jc.2009-0923
  • Skinningsrud, Beate; Lie, Benedicte Alexandra; Husebye, Eystein; Kvien, TK; Førre, Øystein Thorleiv; Flatø, Berit; Stormyr, Alice; Joner, Geir; Njølstad, Pål R.; Egeland, Thore; Undlien, Dag Erik. 2009. A CLEC16A variant confers risk for juvenile idiopathic arthritis and anti-CCP negative rheumatoid arthritis. Annals of the Rheumatic Diseases. Publisert 2009-09-01. doi: 10.1136/ard.2009.114934
  • Aarhus, Mads; Bruland, Ove; Bredholt, Geir; Lybæk, Helle; Husebye, Eystein Sverre; Krossnes, Bård Kronen; Vedeler, Christian A.; Wester, Knut; Lund-Johansen, Morten; Knappskog, Per. 2008. Microarray analysis reveals down-regulation of the tumour suppressor gene WWOX and up-regulation of the oncogene TYMS in intracranial sporadic meningiomas. Journal of Neuro-Oncology. 88: 251-259. doi: 10.1007/s11060-008-9569-6
  • Alimohammadi, Mohammad; Björklund, Peyman; Hallgren, Åsa; Pöntynen, Nora; Szinnai, Gabor; Shikama, Noriko; Keller, Marcel P.; Ekwall, Olov; Kinkel, Sarah A.; Husebye, Eystein Sverre; Gustafsson, Jan; Rorsman, Fredrik; Peltonen, Leena; Betterle, Corrado; Perheentupa, Jaakko; Åkerström, Göran; Westin, Gunnar; Scott, Hamish S.; Holländer, Georg A.; Kämpe, Olle. 2008. Autoimmune polyendocrine syndrome type 1 and NALP5, parathyroid autoantigen. New England Journal of Medicine. 358: 1018-1028.
  • Bratland, Eirik; Husebye, Eystein Sverre. 2008. 21-hydroxylase as a T cell autoantigen in autoimmune Addison's disease. Scandinavian Journal of Immunology. 68: 191-191.
  • Husebye, Eystein Sverre. 2008. Endokrinologisk akuttmedisin. Tidsskrift for Den norske legeforening. 128: 574.
  • Kisand, Kai; Link, Maire; Wolff, Anette Susanne Bøe; Meager, A; Meager, Anthony; Tserel, Liina; Org, Tönis; Murumagi, Astrid; Uibo, Raivo; Willcox, Nick; Podkrajsek, Katarina Trebusak; Battelino, Tadej; Lobell, Anna; Kampe, O; Kämpe, Olle; Lima, Kari; Meloni, Antonella; Ergun-Longmire, Berrin; Maclaren, Noel K.; Perheentupa, Jaakko; Krohn, Kai J.E.; Scott, Hamish S.; Husebye, Eystein Sverre; Peterson, Pärt. 2008. Interferon autoantibodies associated with AIRE deficiency decrease the expression of IFN-stimulated genes. Blood. 112: 2657-2666. doi: 10.1182/blood-2008-03-144634
  • Løvås, Kristian; Husebye, Eystein Sverre. 2008. Replacement therapy for Addison's disease: recent developments. Expert Opinion on Investigational Drugs. 17: 497-509. doi: 10.1517/13543784.17.4.497
  • Magitta, Ng'weina Francis; Pura, Mikulás; Wolff, Anette Susanne Bøe; Vanuga, Peter; Meager, Anthony; Knappskog, Per; Husebye, Eystein Sverre. 2008. Autoimmune polyendocrine syndrome type I in Slovakia: relevance of screening patients with autoimmune Addison's disease. European Journal of Endocrinology. 158: 705-709. doi: 10.1530/EJE-07-0843
  • Magitta, Ng’weina Francis; Bøe, AS; Johansson, S; Skinningsrud, Beate; Lie, Benedicte Alexandra; Myhr, KM; Undlien, Dag Erik; Joner, Geir; Njølstad, Pål R.; Kvien, Tore Kristian; Førre, Øystein Thorleiv; Knappskog, P.M.; Husebye, Eystein. 2008. A coding polymorphism in NALP1 confers risk for autoimmune Addison's disease and type 1 diabetes. Genes and Immunity. doi: 10.1038/gene.2008.85
  • Meloni, Antonella; Furcas, Maria; Cetani, Filomena; Marcocci, Claudio; Falorni, Alberto; Perniola, Roberto; Pura, Mikulás; Wolff, Anette Susanne Bøe; Husebye, Eystein Sverre; Lilic, Desa; Ryan, Kelli R.; Gennery, Andrew R.; Cant, Andrew J.; Abinun, Mario; Spickett, Gavin P.; Arkwright, Peter D.; Denning, David; Costigan, Colm; Dominguez, Maria; McConnell, Vivienne; Willcox, Nick; Meager, Anthony. 2008. Autoantibodies against Type I Interferons as an Additional Diagnostic Criterion for Autoimmune Polyendocrine Syndrome Type I. Journal of Clinical Endocrinology and Metabolism. 93: 4389-4397. doi: 10.1210/jc.2008-0935
  • Oftedal, Bergithe Eikeland; Wolff, Anette Susanne Bøe; Bratland, Eirik; Kämpe, Olle; Perheentupa, Jaakko; Myhre, Anne Grethe; Meager, Anthony; Purushothaman, Radhika; Ten, Svetlana; Husebye, Eystein Sverre. 2008. Radioimmunoassay for autoantibodies against interferon omega; its use in the diagnosis of autoimmune polyendocrine syndrome type I. Clinical Immunology. 129: 163-169. doi: 10.1016/j.clim.2008.07.002
  • Skinningsrud, Beate; Husebye, Eystein Sverre; Gervin, Kristina; Løvås, Kristian; Lovas, K; Blomhoff, Anne; Wolff, Anette Susanne Bøe; Kemp, E. Helen; Egeland, Thore; Undlien, Dag E. 2008. Mutation screening of PTPN22: association of the 1858T-allele with Addison's disease. European Journal of Human Genetics. 16: 977-982. doi: 10.1038/ejhg.2008.33
  • Skinningsrud, Beate; Husebye, Eystein Sverre; Pearce, Simon H.; McDonald, David O.; Brandal, Kristin; Wolff, Anette Susanne Bøe; Løvås, Kristian; Lovas, K; Egeland, Thore; Egeland, Torstein; Undlien, Dag Erik. 2008. Polymorphisms in CLEC16A and CIITA at 16p13 are associated with primary adrenal insufficiency. Journal of Clinical Endocrinology and Metabolism. 93: 3310-3317. doi: 10.1210/jc.2008-0821
  • Wolff, Anette Susanne Bøe; Oftedal, Bergithe Eikeland; Johansson, Stefan; Bruland, Ove; Løvås, Kristian; Meager, Anthony; Pedersen, Carsten; Husebye, Eystein Sverre; Knappskog, Per. 2008. AIRE variations in Addison's disease and autoimmune polyendocrine syndromes (APS): partial gene deletions contribute to APS I. Genes and Immunity. 9: 130-136. doi: 10.1038/sj.gene.6364457
  • Bensing, Sophie; Fetissov, Sergueï O.; Mulder, Jan; Perheentupa, Jaakko; Gustafsson, Jan; Husebye, Eystein S.Junior; Oscarson, Mikael; Ekwall, Olov; Crock, Patricia A.; Hökfelt, Tomas; Hulting, Anna-Lena; Kämpe, Olle. 2007. Pituitary autoantibodies in autoimmune polyendocrine syndrome type 1. Proceedings of the National Academy of Sciences of the United States of America. 104: 949-954. doi: 10.1073/pnas.0610070104
  • Bratland, Eirik; Wolff, Anette Susanne Bøe; Haavik, Jan; Kämpe, Olle; Sköldberg, Filip; Perheentupa, Jaakko; Bredholt, Geir; Knappskog, Per; Husebye, Eystein S.Junior. 2007. Epitope mapping of human aromatic L-amino acid decarboxylase. Biochemical and Biophysical Research Communications - BBRC. 353: 692-698. doi: 10.1016/j.bbrc.2006.12.080
  • Bratland, Eirik; Wolff, Anette Susanne Bøe; Haavik, Jan; Kämpe, Olle; Sköldberg, Filip; Perheentupa, Jaakko; Bredholt, Geir; Knappskog, Per; Husebye, Eystein Sverre. 2007. Epitope mapping of human aromatic L-amino acid decarboxylase. Scandinavian Journal of Immunology. 65: 592-592.
  • Løvås, Kristian; Husebye, Eystein S.Junior. 2007. Continuous subcutaneous hydrocortisone infusion in Addison's disease. European Journal of Endocrinology. 157: 109-112. doi: 10.1530/EJE-07-0052
  • Sanaker, Petter Schandl; Husebye, Eystein S.Junior; Fondenes, Ove; Bindoff, Laurence. 2007. Clinical evolution of Kearns-Sayre syndrome with polyendocrinopathy and respiratory failure. Acta Neurologica Scandinavica. 115: 64-67. doi: 10.1111/j.1600-0404.2007.00850.x
  • Wolff, Anette Susanne Bøe; Erichsen, Martina Moter; Meager, Anthony; Magitta, Ng'weina Francis; Myhre, Anne Grethe; Bollerslev, Jens; Fougner, Kristian J; Lima, Kari; Knappskog, Per; Husebye, Eystein S.Junior. 2007. Autoimmune polyendocrine syndrome type 1 in Norway: Phenotypic variation, autoantibodies, and novel mutations in the autoimmune regulator gene. Journal of Clinical Endocrinology and Metabolism. 92: 595-603. doi: 10.1210/jc.2006-1873
  • Wolff, Anette Susanne Bøe; Myhr, Kjell-Morten; Vedeler, Christian A.; Husebye, Eystein S.Junior. 2007. Fc gamma receptor polymorphisms are not associated with autoimmune Addison's disease. Scandinavian Journal of Immunology. 65: 555-558. doi: 10.1111/j.1365-3083.2007.01932.x
  • Bredholt, Geir; Storstein, Anette Margrethe; Haugen, Monica; Krossnes, Bård Kronen; Husebye, Eystein S.Junior; Knappskog, Per; Vedeler, Christian A. 2006. Detection of autoantibodies to the BTB-kelch protein KLHL7 in cancer sera. Scandinavian Journal of Immunology. 64: 325-335. doi: 10.1111/j.1365-3083.2006.01821.x
  • Husebye, Eystein S.Junior; Bratland, Eirik; Bredholt, Geir; Fridkin, Mati; Dayan, Molly; Mozes, Edna. 2006. The substrate-binding domain of 21-hydroxylase, the main autoantigen in autoimmune Addison's disease, is an immunodominant T cell epitope. Endocrinology. 147: 2411-2416. doi: 10.1210/en.2006-0018
  • Løvås, Kristian; Thorsen, Thor Elias; Husebye, Eystein S.Junior. 2006. Saliva cortisol measurement: simple and reliable assessment of the glucocorticoid replacement therapy in Addison's disease. Journal of Endocrinological Investigation. 29: 727-731.
  • Meager, Anthony; Visvalingam, Kumuthini; Peterson, Pärt; Möll, Kaidi; Murumagi, Astrid; Krohn, Kai; Eskelin, Petra; Perheentupa, Jaakko; Husebye, Eystein S.Junior; Kadota, Yoshihisa; Willcox, Nick. 2006. Anti-interferon autoantibodies in autoimmune polyendocrinopathy syndrome type 1. PLoS Medicine. 3: 1152-1164. doi: 10.1371/journal.pmed.0030289
  • Blomhoff, Anne; Kemp, EH; Gawkrodger, DJ; Weetman, AP; Husebye, ES; Akselsen, Hanne Elisabeth; Lie, Benedicte Alexandra; Undlien, Dag Erik. 2005. CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Research. 18.
  • Blomhoff, Anne; Kemp, Helen; Gawkrodger, David J.; Weetman, Anthony P.; Husebye, Eystein S.Junior; Akselsen, Hanne E.; Lie, Benedicte A.; Undlien, Dag E. 2005. CTLA4 polymorphisms are associated with vitiligo, in patients with concomitant autoimmune diseases. Pigment Cell Research. 18: 55-58.
  • Husebye, Eystein S.Junior; Sthoeger, Zev M.; Dayan, Molly; Zinger, Heidy; Elbirt, Daniel; Levite, Mia; Mozes, Edna. 2005. Autoantibodies to a NR2A peptide of the glutamate/NMDA receptor in sera of patients with systemic lupus erythematosus. Annals of the Rheumatic Diseases. 64: 210-213. doi: 10.1136/ard.2004.029280
  • Løvås, K; Erichsen, Martina M.; Husebye, ES; Fougner, Kristian J.; Svartberg, Johan; Mella, Bjarne; Myhre, Anne Grethe; Berg, Jens Petter; Aarskog, Dagfinn. 2005. Primær binyrebarksvikt - årsaker, diagnostikk og behandling. Tidsskrift for Den norske legeforening. 125: 155-158.
  • Løvås, Kristian; Erichsen, Martina Moter; Husebye, Eystein S.Junior; Fougner, Kristian J; Svartberg, Johan; Mella, B; Myhre, Anne Grethe; Berg, Jens Petter; Aarskog, Dagfinn. 2005. Primær binyrebarksvikt - årsaker, diagnostikk og behandling (=Primary adrenal failure - Causes, diagnostics and therapy). Tidsskrift for Den norske legeforening. 125: 155-158.
  • Løvås, Kristian; Husebye, Eystein S.Junior. 2005. Addison's disease. The Lancet. 365: 2058-2061.
  • Blomhoff, Anne; Lie, Benedicte a.; Myhre, A.G.; Kemp, Helen; Weetman, Anthony P.; Akselsen, Hanne E.; Husebye, Eystein S.Junior; Undlien, Dag E. 2004. Polymorphisms in the cytotoxic T lymphocyte antigen-4 gene region confer susceptibility to Addison's disease. Journal of Clinical Endocrinology and Metabolism. 89: 3474-3476.
  • Bøe, Anette Susanne; Bredholt, G.; Knappskog, Per; Storstein, A.; Vedeler, Christian A.; Husebye, Eystein S.Junior. 2004. Pyridoxal phosphatase is a novel cancer autoantigen in the central nervous system. British Journal of Cancer. 91: 1508-1514.
  • Bøe, Anette Susanne; Bredholt, Geir; Knappskog, Per; Hjelmervik, Trond Ove; Mellgren, Gunnar; Winqvist, Ola; Kämpe, Olle; Husebye, Eystein S.Junior. 2004. Autoantibodies against 21-hydroxylase and side-chain cleavage enzyme in autoimmune Addison's disease are mainly immunoglobulin G1. European Journal of Endocrinology. 150: 49-56.
  • Løvås, Kristian; Husebye, Eystein S.Junior. 2004. Replacement therapy in Addison's disease. Expert Opinion on Pharmacotherapy. 4: 2145-2149.
  • Myhre, Anne Grethe; Stray-Pedersen, A.; Spangen, S.; Eide, E.; Veimo, D.; Knappskog, Per; Abrahamsen, T.G.; Husebye, Eystein S.Junior. 2004. Chronic mucocutaneous candidiasis and primary hypothyroidism in two families. European Journal of Pediatrics. 163: 604-611.
  • Myhre, Anne Grethe; Stray-Pedersen, Asbjørg; Eide, E; Veimo, D.; Knappskog, P.M.; Abrahamsen, Tore G; Husebye, ES. 2004. Chronic mucocutaneous candidiasis and primary hypothyroidism in two families. European Journal of Pediatrics. 163: 604-611.
  • Skoldberg, F.; Rorsman, F.; Perheentupa, J.; Landin-Olsson, M.; Husebye, Eystein S.Junior; Gustafsson, J.; Kämpe, O. 2004. Analysis of antibody reactivity against cysteine sulfinic acid decarboxylase, a pyridoxal phosphate-dependent enzyme, in endocrine autoimmune disease. Journal of Clinical Endocrinology and Metabolism. 89: 1636-1640.
  • Storstein, A.; Monstad, Sissel Evy; Nakkestad, Hanne Linda; Husebye, Eystein S.Junior; Vedeler, Christian A. 2004. Paraneoplastic antibodies against HuD detected by a sensitive radiobinding assay. Journal of Neurology. 251: 197-203.
  • Søderbergh, Annika; Myhre, A.G.; Ekwall, Olov; Gebre-Medhin, Gennet; Hedstrand, Håkan; Landgren, Eva; Miettinen, Aaro; Eskelin, Petra; Halonen, Maria; Tuomi, Tiinamaija; Gustafsson, Jan; Husebye, Eystein S.Junior; Perheentupa, J.; Gylling, Mikhail; Manns, Michael P.; Rorsmann, Fredrik; Kämpe, Olle; Nilsson, Thomas. 2004. Prevalence and clinical associations of 10 defined autoantibodies in autoimmune polyendocrine syndrome type I. Journal of Clinical Endocrinology and Metabolism. 89: 544-547.
  • Løvås, Kristian; Cooper, J.G.; Thorsen, T.; Thordarson, H.; Husebye, Eystein. 2003. Døgnrytme til besvær. Tidsskrift for Den norske legeforening. 123: 1858-1859.
  • Løvås, Kristian; Husebye, Eystein. 2003. Replacement therapy in Addison's disease. Expert Opinion on Pharmacotherapy. 4: 2145-2149.
  • Løvås, Kristian; Trovik, Thor S; Fougner, Kristian J; Uhlving, Sverre; Nedrebø, Bjørn Gunnar; Myking, Ole Langeland; Husebye, Eystein. 2003. Replacement of Dehydroepiandrosterone in Adrenal Failure: No Benefit for Subjective Healt Status and Sexuality in a 9-Month, Randomized, Parallel Group Clinical Trial. Journal of Clinical Endocrinology and Metabolism. 88: 1112-1118.
  • Myhre, Anne Grethe; Aarsetøy, H.; Undlien, D.E.; Hovdenak, N.; Aksnes, L.; Husebye, Eystein. 2003. High frequency of coeliac disease among patients with autoimmune adrenocortical failure. Scandinavian Journal of Gastroenterology. 38: 511-515.
  • Sköldberg, Filip; Portela-Gomes, Guida M.; Grimelius, Lars; Nilsson, Gunnar; Perheentupa, Jaakko; Betterle, Corrado; Husebye, Eystein; Gustafsson, Jan; Rönnblom, Anders; Rorsman, Fredrik; kÄMPE, oLLE. 2003. Histidine decarboxylase, a pyridoxal phosphate-dependent enzyme, is an autoantigen of gastric enterochromaffin-like cells. Journal of Clinical Endocrinology and Metabolism. 88: 1445-1452.
  • Bøe, Anette Susanne; Knappskog, Per Morten; Myhre, Anne Grete; Sørheim, Jan I; Husebye, Eystein. 2002. Mutational analysis of the autoimmune regulator gene in sporadic autoimmune Addison`s disease can reveal patients with unidentified autoimmune polyendocrine syndrome type I. European Journal of Endocrinology. 146: 519-522.
  • Halonen, Maria; Bjørses, Petra; Myhre, Anne Grethe; Perheentupa, Jaako; Husebye, Eystein; kÄMPE, oLLE; Rorsman, Fredrik; Peltonen, Leena; Ulmanen, Ismo; Partanen, J. 2002. Autoimmune Regulator and Human Leucocyte Antigen Genotypes as Determinants of the Autoimmune Polyendocrinopathy-Candidiasis-Ectodermal Dystrophy Phenotype. Journal of Clinical Endocrinology and Metabolism. 87: 2568-2574.
  • Husebye, Eystein. 2002. Hypotyreose. Tidsskrift for Den norske legeforening. 122: 983-983.
  • Løvås, Kristian; Husebye, Eystein. 2002. High prevalence and increasing incidence of Addison's disease in western Norway. Clinical Endocrinology. 56: 787-791.
  • Løvås, Kristian; Loge, Jon Håvard; Husebye, Eystein. 2002. Subjective health status in Norwegian patients with Addison's disease. Clinical Endocrinology. 56: 581-588.
  • Myhre, Anne Grethe; Undlien, Dag Erik; Løvås, Kristian; Uhlving, Sverre; Nedrebø, Bjørn; Fougner, Kristian; Trovik, Thor; Sørheim, Jan Inge; Husebye, Eystein. 2002. Autoimmune adrenocortical failure in Norway. Autoantibodies and HLA class II associations related to clinical features. Journal of Clinical Endocrinology and Metabolism. 87: 618-623.
  • Nedrebø, Bjørn G; Holm, Pål Ivar; Uhlving, Sverre; Sørheim, Jan I; Skeie, Svein; Eide, Geir Egil; Husebye, Eystein; Lien, Ernst Asbjørn; Aanderud, Sylvi J. 2002. Predictors of outcome and comparison of different drug regimens for the prevention of relapse in patients with Graves' disease. European Journal of Endocrinology. 147: 583-589.
  • Nesje, Lars Birger; Varhaug, Jan Erik; Husebye, Eystein; Ødegaard, Svein. 2002. Endoscopic ultrasonography for preoperative diagnosis and localization of insulinomas. Scandinavian Journal of Gastroenterology. 37: 732-737.
  • Astuti, D.; Latif, F.; Dallol, A.; Dahia, P. L.; Douglas, F.; George, E.; Skoldberg, F.; Husebye, Eystein; Eng, C.; Maher, E. R. 2001. Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma. American Journal of Human Genetics. 69: 49-54.
  • Hedstrand, Håkan; Ekwall, Olov; Olsson, Mats J.; Landgren, Eva; Kemp, E. Helen; Weetman, Anthony P.; Perheentupa, Jaakko; Husebye, Eystein; Gustafsson, Jan; Betterle, Corrado; Kämpe, Olle; Rorsman, Fredrik. 2001. The transcription factors SOX9 and SOX10 are vitiligo autoantigens in autoimmune polyendocrine syndrome type I. Journal of Biological Chemistry. 276: 35390-35395.
  • Husebye, Eystein. 2001. Acute adrenal insufficiency--symptoms and treatment. Tidsskrift for Den norske legeforening. 121: 1260.
  • Myhre, Anne Grethe; Halonen, M.; Eskelin, P.; Ekwall, Olov; Hedstrand, Håkan; Rorsman, Fredrik; Kämpe, Olle; Husebye, Eystein. 2001. Autoimmune polyendocrine syndrome type 1 (APS I) in Norway. Clinical Endocrinology. 54: 211-217.
  • Ekwall, O; Hedstrand, HH; Haavik, Jan; Perheentupa, J; Betterle, C; Gustafsson, J; Husebye, Eystein S.Junior; Kämpe, O; Rorsman, F. 2000. Pteridin dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 85: 2944-2950.
  • Ekwall, Olov; Hedstrand, Håkan; Haavik, Jan; Perheentupa, Jaakko; Betterle, Corrado; Gustafsson, Jan; Husebye, Eystein; Rorsman, Fredrik; Këmpe, Olle. 2000. Pteridine-dependent hydroxylases as autoantigens in autoimmune polyendocrine syndrome type 1. Journal of Clinical Endocrinology and Metabolism. 85: 2944-2950.
  • Gebre-Medhin, S; Husebye, Eystein; Mallmin, H; Helström, L; Berne, C; Karlsson, FA; Kämpe, O. 2000. Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. Clinical Endocrinology. 52: 775-780.
  • Gebre-Medhin, [Mangler fornavn]; Husebye, Eystein S.Junior; Mallmin, H; Helström, L; Berne, C; Karlsson, FA; Kämpe, O. 2000. Oral dehydroepiandrosterone (DHEA) replacement therapy in women with Addison's disease. Clinical Endocrinology. 52: 775-780.
  • Hedstrand, HH; Ekwall, O; Haavik, Jan; Landgren, E; Betterle, J; Perheentupa, J; Gustafsson, J; Husebye, Eystein S.Junior; Rorsman, F; Kämpe, O. 2000. Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 267: 456-461.
  • Hedstrand, Håkan; Ekwall, Olov; Haavik, Jan; Landgren, E.; Betterle, Corrado; Perheentupa, Jaakko; Gustafsson, Jan; Husebye, Eystein; Rorsman, Fredrik; Këmpe, Olle. 2000. Identification of tyrosine hydroxylase as an autoantigen in autoimmune polyendocrine syndrome type I. Biochemical and Biophysical Research Communications - BBRC. 267: 456-461.
  • Husebye, Eystein S.Junior; Bøe, Anette Susanne; Rorsman, F; Kämpe, O; Aakvaag, A; Rygh, T; Flatmark, Torgeir; Haavik, Jan. 2000. Inhibition of aromatic 1-amino acid decarboxylase by human autoantibodies. Clinical and Experimental Immunology. 120: 420-423.
  • Husebye, Eystein; Bøe, Anette Susanne; Rorsman, Fredrik; Këmpe, Olle; Aakvaag, T.; Rygh, T.; Flatmark, Torgeir; Haavik, Jan. 2000. Inhibition of aromatic L-amino acid decarboxylase activity by human autoantibodies. Clinical and Experimental Immunology. 120: 420-423.
Rapporter/avhandlinger
  • Husebye, Eystein. 2000. Feokromocytom i Neuroindokrine tumorer, en veiledning til diagnostikk og behandling. MANGLER. 2 sider.
  • Husebye, Eystein S.Junior. 2000. Feokromocytom i Neuroindokrine tumorer, en veiledning til diagnostikk og behandling. Ukjent, Ukjent. 2 sider.
Bokkapitler
  • Husebye, Eystein Sverre. 2017. Binyresykdommer. 18, sider 219-230. I:
    • Birkeland, Kåre I.; Gullestad, Lars; Aabakken, Lars. 2017. Indremedisin I & II. 1056 sider. ISBN: 9788241207402.
  • Husebye, Eystein. 2003. Cushings syndrom. 49-56. I:
    • Johansen, Liv; Moene, Astrid; Huseth, Gerd Kari; Berg, Arnfinn. 2003. Livsboka. 151 sider. ISBN: 82-303-0058-5.

Se fullstendig oversikt over publikasjoner i CRIStin.

Ten papers of special significance

1. Ueland GÅ, Methlie P, Jøssang DE, Sagen JV, Viste K, Thordarson HB, Heie A, Grytaas M, Løvås K, Biermann M, Husebye ES. Adrenal Venous Sampling for Assessment of Autonomous Cortisol Secretion. J Clin Endocrinol Metab. 2018 Dec 1;103(12):4553-4560. First major study showing the importance of adrenal venous sampling in the evaluation of adrenal Cushing’s syndrome.

2. Ueland GÅ, Methlie P, Øksnes M, Thordarson HB, Sagen J, Kellmann R, Mellgren G, Ræder M, Dahlqvist P, Dahl SR, Thorsby PM, Løvås K, Husebye ES. The short cosyntropintest revisited - new normal reference range using LCMSMS. J Clin Endocrinol Metab. 2018 Feb 14. doi: 10.1210/jc.2017-02602. [Epub ahead of print]. First major re-evaluation of the short synacthen test using LCMSMS.

3. Husebye ES, Anderson MS, Kämpe O. Autoimmune polyendocrine syndromes. New Engl.J Med, 378, 1132-41, 2018 (IF 72.4). Invited review that summarizes the current status on polyendocrine syndromes.

4. Orlova EM, Sozaeva LS, Kareva MA, Oftedal BE, Wolff ASB, Breivik L, Zakharova EY, Ivanova ON, Kämpe O, Dedov II, Knappskog PM, Peterkova VA, and Husebye ES. Expanding the phenotypic and genotypic landscape of autoimmune polyendocrine syndrome type-1. J Clin Endocrinol Metabol 102, 3546-56, 2017 (IF 5.5). Clinical and immunological characterization of the hitherto largest cohort of patients with autoimmune polyendocrine syndrome type 1 in the world.

5. Landegren N, Sharon D, Shum AK, Khan IS, Fasano K, Hallgren Å, Kampf C, Freyhult E, Ardesjö-Lundgren B, Alimohammadi M, Rathsman S, Ludvigsson JF, Hedelin H, Lundh D, Motrich R, Rivero V, Fong L, Giwercman A, Gustafsson J, Perheentupa J, Husebye ES, Anderson MS, Snyder M, Kämpe O. Prostatic transglutaminase 4 as a male-specific autoantigen. Science Trans Med 2015 7(292):292ra101. (IF 16.8). Identification of transglutaminase 4 as the first geneder-specific autoantigen assosiated with autoimmune prostatitis. Transglutaminase 4 is an autoantigen in both humans and in autoimmune regulator knockout mice. Furthermore it was demonstrated that transglutaminase 4 belows to the family of aire-regulated genes.

6. Chuprin C, Avin A, Goldfarb Y, Herzig Y, Levi B, Jacob A, Sela A, Katz S1, Grossman M, Guyon C, Rathaus M, Cohen H, Sagi I, Giraud M, McBurney M, Husebye ES, Abramson J. Sirt1 is essential for Aire-mediated induction of central immunological tolerance. Sirt1 is an essential regulator of Aire-mediated induction of central immunological tolerance. Nature Immunology 16,737-45, 2015, (IF 21.5). Demonstration of Sirtuin-1 as a key regulator of AIRE by deacetylation using mouse models. Sirt1-mutations have been described in monogenic autoimmune diabetes mellitus type 1

7. Oftedal BE, Hellesen A, Erichsen MM, Bratland B, Vardi A, Perheentupa J, Kemp EH, Fiskerstrand T, Viken MK, Weetman AP, Fleishman SJ, Banka S, Newman WG, Sewell WAC, Sozaeva LG, Zayats T, Haugarvoll K, Orlova EM, Haavik J Johansson S, Knappskog PM, Løvås L, Wolff ASB, Abramson J, Husebye ES. Dominant Autoimmune Regulator mutations associated with common organ-specific autoimmune diseases. Immunity 42,1185-96, 2015. (IF 22.8). Identification of a new mechanism for familial autoimmunity by identification of several dominant negative mutations in the autoimmune regulator gene. The study includes clinical and immunological characterization of patients as well as functional studies of the mutants demonstrating the dominant negative effect. The paper was accompanied by an editorial and front page cover illustration (June issue).

8. Dawoodji A, Chen JL, Shepherd D, Dalin F, Tarlton A, Alimohammadi M, Penna-Martinez M, Meyer G, Mitchell AL, Gan EH, Bratland E, Bensing S, Husebye ES, Pearce SH, Badenhoop K, Kämpe O, Cerundolo V. High Frequency of Cytolytic 21-Hydroxylase-Specific CD8+ T Cells in Autoimmune Addison's Disease Patients. J Immunol 193, 2118-26, 2014 (IF 4.8). Demonstration of both CD8 and CD4 T cell reativity against 21-hydroxylase and identification of distinct epitopes, building on previous observation by us Bratland et al JCEM, 2009 and Husebye et al, Endocrinology, 2005.

9. Mitchell AL, Macarthur KD, Gan EH, Baggott LE, Wolff AS, Skinningsrud B, Platt H, Short A, Lobell A, Kämpe O, Bensing S, Betterle C, Kasperlik-Zaluska A, Zurawek M, Fichna M, Kockum I, Nordling Eriksson G, Ekwall O, Wahlberg J, Dahlqvist P, Hulting AL, Penna-Martinez M, Meyer G, Kahles H, Badenhoop K, Hahner S, Quinkler M, Falorni A, Phipps-Green A, Merriman TR, Ollier W, Cordell HJ, Undlien D, Czarnocka B, Husebye ES, Pearce SH. Association of autoimmune Addison's disease with alleles of STAT4 and GATA3 in European cohorts. Plos One, 9(3):e88991. doi: 10.1371/journal.pone.0088991. eCollection 2014. (IF 3.5). Results of a FP7-Euradrenal (coordinator Husebye) to find novel disease associations in autoimmune Addison’s disease involving Addison cohorts from 6 European countries totalling over 2000 patients with autoimmune Addison’s disease. Several novel associations were found including GATA3 and STAT4

10. Oksnes M, Björnsdottir S, Isaksson M, Methlie P, Carlsen S, Nilsen RM, Broman JE, Triebner K, Kämpe O, Hulting AL, Bensing S, Husebye ES, Løvås K. Continuous Subcutaneous Hydrocortisone Infusion versus Oral Hydrocortisone Replacement for Treatment of Addison's Disease: A Randomized Clinical Trial. J Clin Endocrinol Metabol 99,1665-74, 2014. (IF 5.5). Clinical study of circadian cortisol treatment first introduced by us. Using subcutaneous cintinous infusion of cortisol by an insulin pump we were able to restore circadian levels of cortisol. The preatment was safe and patients reported improved quality of life.

Spesialist i endokrinologi og indremedisin

Leder K.G. Jebsen-senter for autoimmune sykdommer

Koordinator av H2020 Ultradian