Centre for Cancer Biomarkers CCBIO
Nordic pathology network

Scandinavian Pathology Seminar on August 30-31 2016

CCBIO Director Lars A. Akslen and CCBIO affiliated Arne Östman from Karolinska Institutet initiated and chaired The First Scandinavian Seminar on Translational Pathology. Approximately 50 cancer researchers gathered in the wild west of Sotra at Panorama Hotel outside of Bergen.

Sunset view of the surroundings of Panorama Hotel at Sotra outside of Bergen.
Panorama Hotel

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The intention of the meeting was to create a Scandinavian (or Nordic) network for researchers within tissue based research fields.

The symposium had talks by senior and junior researchers, company presentations and also a poster session. Among several exciting presentations (se program below), Octavian Bucur from Harvard Medical School talked about the new technique of expansion pathology, and the Vice Program Director of The Human Protein Atlas Fredrick Pontén (Uppsala) presented the publicly available database and its vision to include all human proteins. Monica Nistér from Karolinska Institutet presented her pediatric tumor biobank, and work done on brain tumors trying to identify genomic aberrations. Olli Carpén from the University of Turku discussed prognostic biomarkers in endometrial cancer and melanoma. Johan Hartman (Karolinska Institute) discussed the  phylogenetic reconstruction of metastatic breast cancer, whereas Johan Lundin (Helsinki) covered aspects of image analysis and deep learning.

The response after the meeting was very positive. It seems likely that there will be a similar event next year trying to connect Nordic researchers engaged in tissue based research.

The program was as follows:

Day 1: Tuesday - August 30, 2016

  • 09:00-10:00 Registration and Coffee
  • 10:00-10:15 Welcome and Introduction: Arne Östman and Lars A. Akslen

Chair: Arne Östman

  • 10:15-10:45 Fredrick Pontén: The Human Protein Atlas: implications for pathology and clinical medicine.
  • 10:45-11:15 Octavian Bucur: Expansion Pathology: physical tissue expansion in diagnostic pathology
  • 11:15-11:45 Therese Sørlie: Molecular analysis of breast cancer progression
  • 11:45-12:15 Johan Lundin: Deep learning for tissue analytics and outcome prediction in cancer
  • 12:15-12:25 Company presentation: Perkin Elmer

12:25-13:25 LUNCH

Chair: Elisabeth Wik

  • 13:25-13:55 Anna Bofin: Molecular subtypes of breast cancer: Exploiting archival tissue samples to solve the problems of today
  • 13:55-14:25 Patrick Micke: The specificity of lung cancer; targets beyond targeted therapy
  • 14:25-14:55 Olli Carpén: Novel prognostic biomarkers in endometrial cancer and melanoma
  • 14:55-15:25 Monica Nistér: The Pediatric Tumor Biobank
  • 15:25-15:35 Company presentation: Definiens

15:35-16:00 COFFEE

Chair: Therese Sørlie

  • 16:00-16:20 Artur Mezheyeuski: Image analysis of histo-morphological complexity predicts CRC prognosis and treatment response
  • 16:20-16:40 Elisabeth Wik: An angio-immunogenic profile of basal-like breast cancer; relevance of cancer testis antigens
  • 16:40-17:00 Teijo Pellinen: Multi-parametric immunohistochemistry
  • 17:00-17:20 Marit Valla: Molecular subtypes of breast cancer: Trends in incidence and prognosis
  • 17:20-17:30 Company presentation: Visio Pharm

18:00-19:00 POSTERS

19:15 DINNER


Day 2: Wednesday - August 31, 2016

Chair: Even Birkeland

  • 09:00-09:30 Arne Östman: Perivascular cell subsets predicts prognosis and response to treatment
  • 09:30-10:00 Hege Russnes: Intra-tumor heterogeneity in breast carcinomas - a clue to treatment resistance?
  • 10:00-10:30 Johan Hartman: Phylogenetic reconstruction of metastatic breast cancer
  • 10:30-11:00 Lars A. Akslen: Tissue derived markers of tumor-vascular interactions
  • 11:00-11:10 Company presentation: Offspring Biosciences

11:10-11:30 COFFEE

Chair: Lars A. Akslen

  • 11:30-11:50 Monica Engstrøm: HER2 gene copy number in breast cancer. Is CEP17 redundant?
  • 11:50-12:10 Even Birkeland: Proteomic analysis of paraffin embedded breast cancer tissue
  • 12:10-12:30 Per-Henrik Edqvist: The U-CAN biobank initiative; perspectives from first five years
  • 12:30-12:35 Closing remarks

12:35 LUNCH