Tuberculosis Research Group
Tuberculosis (TB), one of the oldest known human diseases, is still one of the major causes of morbidity and mortality globally. Over 90% of TB cases occur in low- and middle-income countries that have fragile healthcare infrastructures and constrained resources.
Main content
The only currently available vaccine for TB was developed about a century ago. TB treatment is long-term and multi-drug resistance is an emerging threat. There is a great need to develop better preventive, diagnostic, and therapeutic tools to curb the epidemic.
Our main research topics are:
- Pathogenesis of human Post-Primary TB (by using the human archival tissue material of the pre-antibiotic era) to generate knowledge base for better vaccines and host-directed therapies
- Development of better diagnostic tests
- Feasibility of implementation of new diagnostic test/s in routine health system settings
- Development of better biomarkers for measurement of therapeutic response
- Disease transmission and infection risk
- Association between Tuberculosis and Obstructive Lung Diseases and Allergies
Current Projects
- Better health through partnership in higher education and bilateral student mobility: Collaboration between Pakistan and Norway (NORPART)
- Pathogenesis of human Post-Primary Tuberculosis: Novel insights from Norwegian archival tissue material of the pre-antibiotic era
- Risk of infection with Mycobacterium tuberculosis in a low tuberculosis prevalence setting
- Association between tuberculosis and obstructive lung diseases and allergies
- Biomarkers in tuberculosis: implications for improved diagnosis, monitoring treatment response, and host-directed therapies
- Proteomic and bioinformatic studies of the host therapeutic response to tuberculosis treatment
- Improving diagnosis of extrapulmonary tuberculosis by implementation of a sensitive and specific assay in routine tuberculosis diagnostics
- DATURA (EDCTP project in 5 African and 2 Asian countries)
Previous Projects
- Localization and characterization of dormant bacilli and host response in chronic tuberculosis and immune evasion strategies of mycobacteria
- Development of new diagnostic test for extrapulmonary tuberculosis
This picture is taken of the group's collaborating partner/institution in TB research in Pakistancollaborating partner/institution in TB research in Pakistan, the Tuberculosis DOTS unit at the Gulab Devi Chest Hospital Research Cell.
Group Members
The Tuberculosis Research Group is headed by Professor Tehmina Mustafa. Learn more.
Group Partners
The Tuberculosis Research Group has many National and International Partners. Learn more.
Publications
Learn more about the group’s publications.
