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Postgraduate course

Phylogenetic Methods

  • ECTS credits5
  • Teaching semesterAutumn
  • Course codeBIO332
  • Number of semesters1
  • Language

    English

  • Resources

Main content

ECTS Credits

5 ECTS

Level of Study

Master and phd.

Teaching semester

Autumn.

This course has a limited capacity, enrolment is based on application. The application deadline is Wednesday in week 33 for the autumn semester. Please see this page for more information. You will receive confirmation of whether you received a seat in Studentweb no later than Monday the week after the deadline.

It is compulsory to attend the first lecture/orientation meeting, or you risk losing your seat. If you are unable to attend the first lecture, you must contact the Study Section (<email>studie.bio@uib.no</email>). The time of the first lecture/orientation meeting can be found in the schedule on the course website or on Mitt UiB.

Place of Instruction

Bergen

Objectives and Content

The course provides a theoretical introduction to phylogenetic methods with topics that deal with different data types, characteristics of phylogenetic trees, models of evolutionary change, phylogenetic signal, model testing, parsimony, "likelihood", Bayesian methods, character reconstruction and phylogenetic hypothesis testing.

Through practical exercises students will gain experience with some of the most frequently used software applications in phylogenetic research. Students will learn to prepare their data and explore its characteristics. They will learn to actively assess alternative methods strengths and weakness and how to design and carry out phylogenetic and comparative studies including various forms of tree search and comparative analyses. Further, students will learn how to present their results with various graphics programs. Finally, students will actively apply learned skills to analyze a dataset, interpret the results and write a comprehensive scientific report.

Learning Outcomes

The course aims to enable students to be able to reproduce key parts of a phylogenetic analysis of a given research publication and to evaluate results and conclusions of such work. Having completed the course, a student is expected to be able to prepare and perform phylogenetic analysis by:

  • using appropriate software to align and compile DNA sequence data
    finding and using relevant "Gene Bank" information about homologous DNA sequences
  • finding the reading frame for a protein coding gene with a relevant codon table
  • concatenating different data sets in one file and defining different partitions of data
  • writing command files to include / exclude parts of the data in various operations
  • finding the best evolutionary models for different data sets and defining these models for use in the applied computer program
  • calculating the tree length and the "likelihood" of a given phylogenetic tree
  • using optimal methods for tree search with parsimony and "likelihood"
  • applying Bayesian methods to search for tree topology, calculation of the clade probability, branch lengths, and parameter values for a given model
  • using different molecular clocks
  • applying various digital graphic formats of phylogenetic trees for publication
  • demonstrating a good understanding of how different phylogenetic tree structures are interpreted as signatures of different evolutionary processes

Required Previous Knowledge

Bachelor's degree in Biology, or equivalent.

Recommended Previous Knowledge

BIO210 Evolutionary Biology (10 ECTS), or equivalent.

Access to the Course

In order to be admitted to the course, you must be admitted to a master¿s programme or the doctoral education (PhD) programme at the Faculty of Mathematics and Natural Sciences and fulfill required previous knowledge.

Compulsory Assignments and Attendance

Attendance at all teaching activities.

Approved compulsory activities are only valid for 1 semester; the semester of completion. Compulsory activities have to be passed in order to take the exam.

Forms of Assessment

Written report in a manuscript form (digital home exam).

Grading Scale

The grading scale used is A to F. Grade A is the highest passing grade, grade F is a fail.

Assessment Semester

The exam will be arranged only in semesters with teaching.

Course Evaluation

Students will evaluate the course in accordance with the quality assurance system at UiB and the Department. You can find course evaluations in the Quality Assurance Reports.

Contact

Contact the Study Section at the Department of Biological Sciences: studie.bio@uib.no">studie.bio@uib.no

Exam information