News archive for Biorecognition
New mental health project aims to uncover insulin-related mechanisms linking disorders of body and brain. (22.01.2020)
An important European-funded initiative has been launched to explore how common molecular mechanisms may link metabolic disorders, especially type 2 diabetes and obesity, with brain disorders such as Alzheimer's disease, obsessive-compulsive disorder, and autism spectrum disorders. Jan Haavik and Aurora Martinez from the Department of Biomedicine are the norwegian participants.
Martinez and collaborators are developing a pharmacological chaperone therapy for acute intermittent porphyria
Researchers from the Department of Biomedicine describe the atomic details responsible for the short length of actin filaments in the malaria parasite.
The Nor-Openscreen application for this year's infrastructure call scored the highest possible marks in all categories! To quote from the reviewer comments: "This is an excellent proposal to enlarge and update existing infrastructure and services in chemical biology in Norway". Despite the very favorable evaluation, the proposal was not funded. This means, there will unfortunately... Read more
Our new paper on entangling selectivity determining features and on how to use this knowledge to design selective ligands has been published in J Med Chem!
The structure of full-length phenylalanine hydroxylase in complex with the cofactor BH4 is presented in the most recent issue of PNAS. As the cofactor is also used as a therapy for PKU, this structure is of medical importance.
Researchers from the lab of Aurora Martinez describe a novel mechanism for the degradation of enzymes involved in phenylketonuria and other neurometabolic disorders.
Towards better computational approaches and responsible innovation strategies in early drug discovery (18.12.2018)
Together with Nathalie Reuter and Bengt-Erik Haug from the Chemistry Department and Alexander Lundervold from the Høgskulen på Vestlandet (HVL) we got funding for the project «Towards better computational approaches and responsible innovation strategies in early drug discovery: application to antibiotics and COPD» under the Centre for Digital Life umbrella. In this project, we are aiming toward... Read more
Our EXPLORE network application aiming at targeting the TPP riboswitch for hit discovery for new antibiotics will receive funding from JPI-AMR! Other partners in the network are Daniel Lafontaine (Université de Sherbrooke, Canada), Matthias Mack (Mannheim University of Applied Sciences, Germany), Petr Bartunek (CZ-OPENSCREEN, Czech Republic), Bengt Erik Haug (University of Bergen Norway) and... Read more
Researcher's Grand Prix-cadidate Illimar Hugo Rekand is working to keep us healthy. He is investigating new opportunities for making new medicines in a world where antibiotic resistance is an increasing challenge.
Ruth Brenk at The Department of biomedicine received a grant of 7 million NOK for research to discover new antibiotics. The work will be carried out with collaborators at the Indian Institute of Chemical Technology.
Researchers at the Department of Biomedicine participate in an international research project that has now found a promising compound which could turn into an effective drug against malaria.
About state-of the art of riboswitch ligand design and future perspectives.
Sarsia Seed recently announced their new seed funds in Bergen consisting of 300 million NOK. Initial investment can be in the biotechnology company Pluvia founded by Prof. Aurora Martinez according to Sarsia officials.
The Brenk lab will receive funding from NFR for developing future antibiotics acting via riboswitch binding. This project will fund two postdoc positions for three years, one in the lab of Bengt Erik Haug (Department of Chemistry) and one in the Brenk group. We are looking forward to continuing an exiting research project!
Biorecognition won the Faculty of Medicine and Dentistry prize for best research group.
In 2014 Ruth was awared nearly 60,000 Euros over two years from the Gutenberg Lehrkolleg for research oriented teaching.
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