Craniofacial Developmental Biology and Regeneration

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The aim of the group is to analyze general molecular signaling mechanisms regulating embryonic organ development in craniofacial and oral tissues.

We use mouse as a model system in order to understand how the mammalian cells form, organize, maintain, regenerate and repair the proper three-dimensional structures of tissues and organs. Knowledge of the molecular regulation of normal development forms a basis for understanding abnormal behavior of cells, for example malignant growth in adult mammalian systems. Our research provides also basic information for engineering biological tissues and organs to replace congenitally missing, damaged or removed cells, tissues or organs in man in the future.

Selected publications