Nuclear lipids: biomolecular interactions and function

Main content

  • F Mazloumi Gavgani, T Karlsson, IL Tangen, A Papdiné Morovicz, V Smith Arnesen, D C Turcu, S Ninzima, K Spang, C Krakstad, J Guillermet-Guibert and AE Lewis (2021). Nuclear upregulation of class I phosphoinositide 3-kinase p110β correlates with increased 47S rRNA levels in cancer cells. Journal Cell Biology. 134(3):jcs246090. doi: 10.1242/jcs.246090. also in bioRxiv. DOI:10.1101/2019.12.20.884122.
  • RG Jacobsen, F Mazloumi Gavgani, AJ. Edson, M Goris, A Altanchimeg and AE Lewis (2019) Polyphosphoinositides in the nucleus: Roadmap of their effectors and mechanisms of interaction. Advances in Biological Regulation. 72: 7-21.

  • F Mazloumi Gavgani, V Smith Arnesen, RG Jacobsen, C Krakstad, EA Hoivik, AE Lewis (2018). Class I Phosphoinositide 3-Kinase PIK3CA/p110α and PIK3CB/p110β Isoforms in Endometrial Cancer. Int J Mol Sci. 19(12). pii: E3931. doi: 10.3390/ijms19123931.
  • T Karlsson, C Krakstad, IL Tangen, EA Hoivik, PM Pollock, HB Salvesen & AE Lewis (2017). Endometrial cancer cells exhibit high expression of p110b and variable response to both p110a and p110b inhibition on PI3K signalling, cell survival and proliferation. Oncotarget. 8:3881-94.
  • Mjos S, Werner HMJ, Birkeland E, Holst F, Berg A, Halle MK, Tangen IL, Kusonmano K, Mauland KK, Oyan AM, Kalland KH, Lewis AE, Mills GB, Krakstad C, Trovik J, Salvesen HB, Hoivik EA (2017). PIK3CA exon9 mutations associate with reduced survival, and are highly concordant between matching primary tumors and metastases in endometrial cancer. Sci. Reports. 7(1):10240. doi: 10.1038/s41598-017-10717-z.
  • Jacobsen RM, Gavgani FM, Mellgren G and AE Lewis (2016). DNA Topoisomerase IIa contributes to the early steps of adipogenesis in 3T3-L1 cells. Cellular Signalling. 28:1593-1603.
  • T Karlsson, A Altanchimeg, O Dobrovolska, DC Turcu and AE Lewis (2016). A polybasic motif in ErbB3-Binding-Protein 1 (EBP1) has key functions in nucleolar localisation and polyphosphoinositide interaction. Biochemical Journal. 473: 2033-47. DOI: 10.1042/BCJ20160274.
  • CS D’Santos and AE. Lewis (2012). Functional Proteomics: Mapping Lipid-Protein Interactomes. Book Chapter. Integrative Proteomics, Hon-Chiu Eastwood Leung (Ed.), ISBN: 978-953-51-0070-6, InTech, Available from: http://www.intechopen.com/articles/show/title/functional-proteomics-mapp...
  • AE Lewis, L Sommer, MØ Arntzen, Y Strahm, NA Morrice, N Divecha and CS D’Santos (2011). Identification of nuclear phosphatidylinositol 4,5-bisphosphate-interacting proteins by neomycin extraction. Molecular & Cellular Proteomics. 10(2):M110.003376. doi:10.1074/mcp.M110.003376.