Professor Bruce Baguley - The vascular endothelial barrier: relevance to cancer therapy
CCBIO Special Seminar with Professor Bruce Baguley from the University of Auckland, title: "The vascular endothelial barrier: relevance to cancer therapy".
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Apart from the interesting talks, the CCBIO seminars are a good way to meet CCBIO members and associates. Please feel free to inform others about this seminar as all are welcome both to the lecture and the pizza get-together afterwards.
Invited speaker: Professor Bruce Baguley, University of Auckland, Auckland Cancer Research Centre, Medical Science, Faculty of Medical and Health Sciences, New Zealand
Title: "The vascular endothelial barrier: relevance to cancer therapy"
Time: May 15th 2017 at 14:30, Auditorium 4, BBB
Chairperson: Jim Lorens
Abstract:
The vascular and extravascular compartments are separated by vascular endothelial cells, which form a barrier that maintains distinct cellular and protein components. The increasing use of antibodies in cancer therapy raises the question of how therapeutic proteins cross this barrier. This talk examines the possible role of Axl, Gas6 and other proteins in the control of vascular permeability. It will also summarise clinical trials of a drug that was designed to disrupt this barrier.