CCBIO904 – Biomarkers and tumor biology in clinical practice
CCBIO904 covers tumor biological aspects important for the understanding of why cancer develops and which mechanisms are important for tumor growth, metastases and morbidity in patients.
When: May 25-27, 2020
Program: Available here (Subject to changes.)
Where: Digital event through Zoom. Access links will be provided to the registered participants.
Who: Mainly intended for PhD candidates, but open to all.
Registration: Through this link.
Responsible: Oddbjørn Straume has the academic responsibility, and Reidun Kopperud is the coordinator.
The 4 ECTS course covers broad tumor biological topics that are important for understanding how cancer occurs, the mechanisms that control tumor growth, proliferation and morbidity. The course will focus especially on tumor biological changes that may have or already have significance for personalized cancer treatment and clinical trial studies of new diagnostics and treatment
The course includes lectures, demonstrations, curriculum and a written exam, and aims to give PhD candidates who does cancer research, a broad understanding of all aspects of tumor biology based on updated knowledge. The PhD candidates will also gain deeper insight into how knowledge about tumor biological changes affects our strategies to customize assessment and treatment for this group of patients.
Registration of ECTS: You need to be registered as a student at the University of Bergen to get the ECTS registered. If you are not, please contact firstname.lastname@example.org to be guided on how to apply for guest student status. If you don't need the ECTS registered as part of an education/degree, and just want a course diploma, you don't need to apply for guest student status.
Upon completing this course the candidate should have:
- Evaluation of the purpose and advantage of using methods to detect molecular changes in malignant lesions.
- Deeper insight into:
- Tumor biological aspects of cancer.
- Oncogenes, tumor-suppressor genes, gene re-arrangements, DNA repair, apoptosis and growth factors.
- Different methods applied for "Gen-mapping". DNA analysis and sequencing.
- Principals for cytokine therapy, gene therapy, rational "drug design," monoclonal antibodies and protein engineering.
- The interaction between tumor cells and microenvironment.
- Relevant methods for specimen collection in the clinical setting for use of molecular techniques.
- Can formulate problems and suggest research of molecular biological aspects in cancer and cancer development in order to map tumor biological mechanisms.
- Be able to critically assess the expediency and challenges of using different methods for researching molecular biological aspects of cancer.
- Be able to select relevant literature that deals with molecular aspects important in cancer.
- Be able to evaluate how knowledge about molecular changes in cancer may provide a better and more precise diagnosis.
- Be able to propose new strategies for development of more targeted therapies and testing of cancer drugs.
- Be able to understand challenges and possibilities for introducing more targeted therapies and better follow up of cancer patients.
Who can participate
The course is primarily intended for PhD candidates who are affiliated with the Centre for Cancer Biomarkers (CCBIO), but is also open to other students, PhD candidates and students attending the designated Medical Student Research Program (forskerlinjen) and other interested researchers. This is a 4 credits course. Others not interested in the ECTS, might also attend. The course is free of charge.