Weight cycling promotes circadian shift and fat gain in C57BL/6J mice

Post doc Simon Dankel and Prof. Gunnar Mellgren in the Hormone Laboratory research group have contributed to a study on the mechanisms by which genetic variants promote type 2 diabetes.

Many genetic loci have been associated with risk of type 2 diabetes (T2D). However, it has remained a major challenge to go from these associations to the causal mechanisms that explain an individual’s risk. Understanding the mechanisms could help develop new effective strategies to prevent and treat T2D in a personalized manner.

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